CN101653562B

CN101653562B - Traditional Chinese medicine for treating erythrodermic psoriasis

Info

Publication number: CN101653562B
Application number: CN2009100661535A
Authority: CN
Inventors: 周大红
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-09-15
Filing date: 2009-09-15
Publication date: 2011-08-31
Anticipated expiration: 2029-09-15
Also published as: CN101653562A

Abstract

The invention belongs to the traditional Chinese medicine field, in particular to a traditional Chinese medicine for treating erythrodermic psoriasis. The active ingredient of the traditional Chinese medicine is made by the following raw materials: crow snake, scorpio, cicada ecdysis, root of rehmannia, root of common peony, the root bark of the peony tree, the stem of noble dendrobium, honeysuckle, lithospermum, salvia miltiorrhiza, Tuckahoe, angelica, vine of multiflower knotweed, suberect spatholobus stem, ophiopogon root, fresh liquorice and chilopod. The traditional Chinese medicine of the invention has reasonable compatibility and effective treatment without side effect.

Description

The psoriasic Chinese medicine of a kind of treatment erythrodermic

(1) technical field

The invention belongs to motherland's medical domain, the psoriasic Chinese medicine of particularly a kind of treatment erythrodermic.

(2) background technology

The erythrodermic psoriasis, account for psoriasic 1.62%, how improper and cause by the homeliness type curing psoriasis, as at the strong medicine of the phase of carrying out external zest, as mustard gas, the salicylic acid preparation of high concentration, the hydrargyrum arsenic preparation, or it is long-time, heavy dose of immunosuppressant such as inferior lung of second of using, bimolane and hormone medicine are as prednisone, cause that erythra is just sent out the extremity of being everlasting and bent side after the drug withdrawals such as ground Sai Zhusong suddenly, the limitation erythema takes place, expand rapidly and prolong whole body, be extensive flushing, a large amount of then desquamations, be the furfur shape, often with heating, fear of cold, headache, General Symptomies such as arthralgia, treatment are obstinate, are easy to recurrence.

The psoriasic method of treatment erythrodermic commonly used at present is interior with 17-hydroxy-11-dehydrocorticosterone or whole body supporting treatment or medicine for external use processing, but the many curative effects of above method are very little and some also has side effect.

(3) summary of the invention

The object of the present invention is to provide psoriasic Chinese medicine of a kind of treatment erythrodermic and preparation method thereof, described treatment by Chinese herbs is effective, has no side effect.

The technical solution used in the present invention is as follows:

The psoriasic Chinese medicine of a kind of treatment erythrodermic, its effective ingredient is made by the raw material of following weight portion:

Zaocys 10-20 Scorpio 3-9 Periostracum Cicadae 5-15 Radix Rehmanniae 10-20 Radix Paeoniae Rubra 5-15

Cortex Moutan 5-15 Herba Dendrobii 5-15 Flos Lonicerae 10-20 Radix Arnebiae (Radix Lithospermi) 10-20 Radix Salviae Miltiorrhizae 20-40

Poria 10-20 Radix Angelicae Sinensis 10-20 Caulis Polygoni Multiflori 10-20 Caulis Spatholobi 20-40 5-15 Radix Ophiopogonis

Radix Glycyrrhizae 3-9 Scolopendra; When above each raw material weight unit was g, the amount of Scolopendra was two.

Further, described raw materials in part by weight is as follows:

Zaocys 15 Scorpio 6 Periostracum Cicadaes 10 Radix Rehmanniae 15 Radix Paeoniae Rubra 10 Cortex Moutans 10 Herba Dendrobiis 10 Flos Lonicerae 15

30 Radix Ophiopogonis 10 of Radix Arnebiae (Radix Lithospermi) 15 Radix Salviae Miltiorrhizaes 30 Poria 15 Radix Angelicae Sinensis 15 Caulis Polygoni Multiflori 15 Caulis Spatholobis

Radix Glycyrrhizae 6.

Described Chinese medicine can be made into pharmaceutically acceptable dosage form arbitrarily for oral administration, and the present invention preferably makes decoction or honeyed pill, gets final product according to the conventional method preparation, repeats no more.

Erythrodermic psoriasis Chinese medical discrimination is that pyretic toxicity is joined the army, stifling skin; Control suitable removing pathogenic heat from blood and toxic substance from the body, assistant is with nourishing yin and activating blood.In the prescription of the present invention, Zaocys, sweet, flat, return Liver Channel; Dispel the wind collateral dredging, relieving convulsion.Scorpio, hot, flat, poisonous, return Liver Channel; Spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain relieve dizziness, high fever, infantile convulsions, epilepsy, etc.Periostracum Cicadae, sweet, cold, return lung, Liver Channel; Diffusing wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.The Radix Rehmanniae, sweet in the mouth, hardship, cold in nature, GUIXIN, liver, lung meridian; Heat clearing and blood cooling, enriching yin and nourishing kidney, promoting the production of body fluid to quench thirst.Radix Paeoniae Rubra, hardship is slightly cold, and returns Liver Channel; Clearing away heat and cooling blood, eliminating stasis to stop pain.Cortex Moutan, hot, bitter, be slightly cold; Clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Herba Dendrobii, sweet, be slightly cold, return stomach, kidney channel; Reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Flos Lonicerae, sweet, cold, return lung, the heart, stomach warp; Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Radix Arnebiae (Radix Lithospermi), sweet, one-tenth, cold; GUIXIN, Liver Channel; Removing heat from blood is invigorated blood circulation, the detoxifcation rash.Radix Salviae Miltiorrhizae, hardship is slightly cold, GUIXIN, Liver Channel; Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Poria, bitter, hot, be slightly cold; Return spleen, stomach, liver, gallbladder meridian; Clearing away damp-heat, the jaundice eliminating subcutaneous ulcer.Radix Angelicae Sinensis, sweet, hot, temperature; Return liver, the heart, spleen channel; Enrich blood and invigorate blood circulation, pain relieving, loosening bowel to relieve constipation.Caulis Polygoni Multiflori, sweet, flat, GUIXIN, Liver Channel; Nourishing blood to tranquillize the mind, dispelling wind and removing obstruction in the collateral.Caulis Spatholobi, bitter, sweet, warm; Return liver, kidney channel; Enrich blood, invigorate blood circulation, collateral dredging.Radix Ophiopogonis, sweet, little hardship is slightly cold; GUIXIN, lung, stomach warp; YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Scolopendra, one-tenth, suffering, temperature, poisonous; Return liver, spleen, lung meridian; Relieve internal heat anticancer, relieving spasm by calming endogenous wind, move back inflammation and control skin ulcer.Radix Glycyrrhizae, sweet, flat, GUIXIN, lung, spleen, stomach warp; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.The effect that above each side medicine cooperates concurrence removing heat from blood, yin nourishing, invigorates blood circulation, detoxifies.

The present invention has following advantage with respect to prior art:

Drug matching of the present invention is reasonable, and is evident in efficacy, has no side effect.

(4) specific embodiment:

Below with specific embodiment technical scheme of the present invention is described, but protection scope of the present invention is not limited thereto:

Embodiment 1

The psoriasic Chinese medicine of treatment erythrodermic, raw material is composed as follows:

Zaocys 10g Scorpio 3g Periostracum Cicadae 5g Radix Rehmanniae 10g Radix Paeoniae Rubra 5g

Cortex Moutan 5g Herba Dendrobii 5g Flos Lonicerae 10g Radix Arnebiae (Radix Lithospermi) 10g Radix Salviae Miltiorrhizae 20g

Poria 10g Radix Angelicae Sinensis 10g Caulis Polygoni Multiflori 10g Caulis Spatholobi 20g 5g Radix Ophiopogonis

Two of Radix Glycyrrhizae 3g Scolopendras.

After above each raw material was smalls altogether, processed with honey was a ball.

Embodiment 2

Zaocys 12g Scorpio 5g Periostracum Cicadae 7.5g Radix Rehmanniae 12g Radix Paeoniae Rubra 7.5g

Cortex Moutan 7.5g Herba Dendrobii 7.5g Flos Lonicerae 12g Radix Arnebiae (Radix Lithospermi) 12g Radix Salviae Miltiorrhizae 25g

Poria 12g Radix Angelicae Sinensis 12g Caulis Polygoni Multiflori 12g Caulis Spatholobi 25g 7.5g Radix Ophiopogonis

Two of Radix Glycyrrhizae 5g Scolopendras.

Embodiment 3

Zaocys 15g Scorpio 6g Periostracum Cicadae 10g Radix Rehmanniae 15g Radix Paeoniae Rubra 10g

Cortex Moutan 10g Herba Dendrobii 10g Flos Lonicerae 15g Radix Arnebiae (Radix Lithospermi) 15g Radix Salviae Miltiorrhizae 30g

Poria 15g Radix Angelicae Sinensis 15g Caulis Polygoni Multiflori 15g Caulis Spatholobi 30g 10g Radix Ophiopogonis

Two of Radix Glycyrrhizae 6g Scolopendras.

Embodiment 4

Zaocys 17g Scorpio 8g Periostracum Cicadae 12.5g Radix Rehmanniae 17g Radix Paeoniae Rubra 12.5g

Cortex Moutan 12.5g Herba Dendrobii 12.5g Flos Lonicerae 17g Radix Arnebiae (Radix Lithospermi) 17g Radix Salviae Miltiorrhizae 35g

Poria 17g Radix Angelicae Sinensis 17g Caulis Polygoni Multiflori 17g Caulis Spatholobi 35g 12.5g Radix Ophiopogonis

Two of Radix Glycyrrhizae 8g Scolopendras.

Above each raw material is added water 750ml decoct 1h, get decoction liquor.

Embodiment 5

Zaocys 20g Scorpio 9g Periostracum Cicadae 15g Radix Rehmanniae 20g Radix Paeoniae Rubra 15g

Cortex Moutan 15g Herba Dendrobii 15g Flos Lonicerae 20g Radix Arnebiae (Radix Lithospermi) 20g Radix Salviae Miltiorrhizae 40g

Poria 20g Radix Angelicae Sinensis 20g Caulis Polygoni Multiflori 20g Caulis Spatholobi 40g 15g Radix Ophiopogonis

Two of Radix Glycyrrhizae 9g Scolopendras.

Above each raw material is added water 800ml decoct 2h, get decoction liquor.

Model case

Zhu, the woman, 16 years old, red macule half a year appearred in the whole body, the adularescent squama, scratching has the petechia after grabbing, and very itches.Find patient's skin lesion kermesinus when examining, a large amount of desquamations do not have heating fear of cold phenomenon.Be diagnosed as the erythrodermic psoriasis.Take the embodiment of the invention 3 honeyed pill, obey 6g at every turn, sooner or later respectively once; Treat recovery from illness after three months, follow up a case by regular visits to so far not recurrence.

Clinical effectiveness:

Clinical disease

Whole skin diffusivity flushing, purplish red, even swelling infiltration, a large amount of desquamations only have minority lamellar skin normal, just as being distributed in the island in the ocean.With palm sole of the foot keratinization, refer to that (toe) first thickens.Whole body is with symptoms such as shiver with cold hyperpyrexia, arthralgia, headache, fear of cold, constipation with dry stool, yellowish or reddish urine, yellow and greasy fur, deep red tongue, stringy and rolling pulse numbers.The state of an illness is shown effect repeatedly, often delays several months or longer time.

Efficacy evaluation

Cure: skin lesion disappears fully, or disappears more than 95%.

Take a turn for the better: skin lesion disappears more than 50%.

Do not heal: the skin lesion less than 50% that disappears.

Statistical result:

Clinical patients is totally 282 people, wherein male 180 people, and women 102 people respectively are divided into two groups; One group is used honeyed pill of the present invention, every day sooner or later each once, each 6g; Another group is taken decoction liquor, every day potion, each approximately 250ml; After 1 to 3 months, take the honeyed pill group, produce effects 83 people, effective 47 people, invalid 11 people, total effective rate is 92.2%; Take the decoction liquor group, produce effects person 95 people, improvement person 34 people, nonresponder 12 people, effective percentage is 91.5%.Follow up a case by regular visits to after 1 year, the responder does not have recurrence.

Claims

1. treat the psoriasic Chinese medicine of erythrodermic for one kind, it is characterized in that its effective ingredient is made by following raw materials in weight:

Zaocys 10-20g Scorpio 3-9g Periostracum Cicadae 5-15g Radix Rehmanniae 10-20g Radix Paeoniae Rubra 5-15g

Cortex Moutan 5-15g Herba Dendrobii 5-15g Flos Lonicerae 10-20g Radix Arnebiae (Radix Lithospermi) 10-20g Radix Salviae Miltiorrhizae 20-40g

Poria 10-20g Radix Angelicae Sinensis 10-20g Caulis Polygoni Multiflori 10-20g Caulis Spatholobi 20-40g Radix Ophiopogonis

Two of 5-15g Radix Glycyrrhizae 3-9g Scolopendras.

2. the psoriasic Chinese medicine of treatment erythrodermic as claimed in claim 1 is characterized in that described raw materials in part by weight is as follows:

Zaocys 15g Scorpio 6g Periostracum Cicadae 10g Radix Rehmanniae 15g Radix Paeoniae Rubra 10g Cortex Moutan 10g Herba Dendrobii 10g

Flos Lonicerae 15g Radix Arnebiae (Radix Lithospermi) 15g Radix Salviae Miltiorrhizae 30g Poria 15g Radix Angelicae Sinensis 15g Caulis Polygoni Multiflori 15g Caulis Spatholobi

30g 10g Radix Ophiopogonis Radix Glycyrrhizae 6g.

3. the psoriasic Chinese medicine of treatment erythrodermic as claimed in claim 1 or 2 is characterized in that described Chinese medicine is decoction or honeyed pill.