CN101647920B - Medicament for treating scar and preparation method thereof - Google Patents

Medicament for treating scar and preparation method thereof Download PDF

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Publication number
CN101647920B
CN101647920B CN2009101692136A CN200910169213A CN101647920B CN 101647920 B CN101647920 B CN 101647920B CN 2009101692136 A CN2009101692136 A CN 2009101692136A CN 200910169213 A CN200910169213 A CN 200910169213A CN 101647920 B CN101647920 B CN 101647920B
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grams
medicine
oleum sesami
olibanum
radix salviae
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CN101647920A (en
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吕松新
吕新旺
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Liu Yue
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Abstract

The invention discloses a medicament for treating scar, which is a pure Chinese medicine ointment preparation prepared from salvia miltiorrhiza, safflower, frankincense, turtle shell, crinis ustus, dragon's blood, leech, calamine, sesame oil, white wax and beeswax according to a certain weight proportion. The medicament has the efficacy of promoting blood circulation by removing blood stasis, inducing meastruation to relieve menalgia, dissipating blood stasis to induce qi, nourishing yin, tonifying yang, relaxing muscles and tonifying blood and has the advantages of quick effect on treating scar and high treating effect.

Description

A kind of medicine of treating cicatrix and preparation method thereof
Technical field
The present invention relates to a kind of medicine of treating cicatrix and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Cicatrix belongs to operation, disease occurred frequently after wound, burn and scald recover from injury.Clinical with scar hyperplasia, contracture, twinge is scratchy is characteristic.Outbreak influences work, sleep often because of environmental stimuli causes violent painful itching, and severe patient causes contracture, causes dysfunction.The medicine for external use of this disease of present treatment, these product expense height of cicatrix subsides, weak effect, the course of treatment that the Kang Ruibao that Germany produces, Shanghai produce are long.
Summary of the invention
The purpose of this invention is to provide a kind of more effective treatment cicatrix Chinese medicine composition.
Another object of the present invention provides the method for preparing of this Chinese medicine composition.
The present invention selects: Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Carapax Trionycis, Crinis Carbonisatus, Sanguis Draxonis, white beeswax, Cera Flava, Oleum Sesami make up.With these drug regimens, make the effect of each medicine produce mutual synergism, thereby treat scar hyperplasia and contracture effectively.The present invention selects for use:
Radix Salviae Miltiorrhizae, Flos Carthami, GUIXIN, lung, Liver Channel, blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia.
Olibanum, Sanguis Draxonis, GUIXIN, liver, spleen channel, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.
Carapax Trionycis, Crinis Carbonisatus are returned liver,spleen,kidney, stomach warp, nourishing YIN for suppressing the hyperactive YANG, hemostasis hard masses softening and resolving.
The effect of all medicine compatibilities: blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, detumescence are active, hard masses softening and resolving, YIN nourishing and YANG strengthening, Shujin are enriched blood; Promote cicatrix flatten deliquescing, antalgesic-antipruritic, near skin color.
In order to obtain better therapeutic, medicine of the present invention can also add water traitor, Calamina on above-mentioned basis.
Wherein the salty hardship of Hirudo nature and flavor is flat, returns the liver urinary bladder channel, blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia.Calamina: nature and flavor are sweet flat, return liver spleen lung meridian, expelling pus and promoting granulation, the antipruritic pain relieving of removing dampness.
The invention provides a kind of medicine of treating cicatrix, its crude drug is: 500 milliliters of Radix Salviae Miltiorrhizae 30~50 grams, Flos Carthami 40~60 grams, Olibanum 30~40 grams, Carapax Trionycis 30~45 grams, Crinis Carbonisatus 15~20 grams, Sanguis Draxonis 30~40 grams, white beeswax 60~75 grams, Cera Flava 25~35 grams, Hirudo 20~30 grams, Calamina 15~30 grams, Oleum Sesami.
The method for preparing of this medicine for example can comprise the following steps:
A) take by weighing each material medicine: Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Carapax Trionycis, Crinis Carbonisatus, Sanguis Draxonis, Hirudo, Calamina, Oleum Sesami are subsequent use.
B) Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Calamina, the Hirudo of said weight proportion added decocting and endure twice, each amount of water was not advisable to have medicine, decocted 1/4th of original water, merged decocting liquid twice.Cross and filter filtrating, make dry extract 1 60~70 ℃ of following dryings.
C) Sanguis Draxonis of said weight proportion is added 90~95% ethanol and purifies, with extracting solution ethanol at 60~70 ℃ of dry down dry extracts 2.
D) Oleum Sesami of said weight proportion is endured to 200 ℃, added Carapax Trionycis, Crinis Carbonisatus fried 15 minutes.Collect and filter Oleum Sesami cold to 80 ℃, add the fine powder of white beeswax, Cera Flava, dry extract 1 and dry extract 2.With its even active ingredient that makes medicine of the present invention that is in harmonious proportion.
The present invention provides the medicine of another kind of treatment cicatrix, and its crude drug is: 500 milliliters of Radix Salviae Miltiorrhizae 40 grams, Flos Carthami 50 grams, Olibanum 35 grams, Carapax Trionycis 40 grams, Crinis Carbonisatus 35 grams, Sanguis Draxonis 35 grams, white beeswax 70 grams, Cera Flava 30 grams, Oleum Sesami.
The method for preparing of this medicine for example can comprise the following steps:
A) take by weighing each crude drug: Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Carapax Trionycis, Sanguis Draxonis, Crinis Carbonisatus, white beeswax, Cera Flava, Oleum Sesami are subsequent use;
B) with Radix Salviae Miltiorrhizae, Olibanum, the Flos Carthami decocte with water twice of said weight, add water at every turn and be not advisable to have medicine, decoct 1/4th of original water, merge decocting liquid twice.Cross and filter filtrating, make dry extract 1 60~70 ℃ of following dryings;
C) Sanguis Draxonis with said weight proportion carries out reflux, extract, at 90~95% ethanol, with extracting the ethanol dry dry extracts 2 that get under 60~70 ℃ that reclaim;
D) Oleum Sesami of said weight proportion is endured to 200 ℃, added Carapax Trionycis, Crinis Carbonisatus boiled 15 minutes.It is cool to 80 ℃ to collect filtrate Oleum Sesami, adds the fine powder of white beeswax, Cera Flava, dry extract 1 and dry extract 2; With its even active component that makes medicine of the present invention that is in harmonious proportion.
The present invention has the effect that blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, removing blood stasis circulation of qi promoting, YIN nourishing and YANG strengthening, Shujin are enriched blood.Be used to treat cicatrix.
The specific embodiment
Accept out-patient's totally 30 examples for medical treatment, wherein male 20 examples, women 15 examples, men and women's ratio 2: 1. the cicatrix area is below 2%, and Common Shape is a point-like, streak, butterfly-shaped.
Therapeutic Method
Medicine is evenly smeared on the cicatrix, massaged every day 1~2 time.Be a course of treatment half a year.
Model case
The patient, Zhao XX, woman, 15 years old, Hengshui City people.The back of the hand portion scalding healing formed shallow table cicatrix in three months, and area is 1%.Smear medicine of the present invention after six months, the painful elimination of itching of cicatrix, the deliquescing that flattens is near skin color.
The patient, horse XX, woman, 21 years old, Hengshui City people from Gucheng.Form dish shape addiction trace behind two first quarter moons of cervical region scalding healing, its area is 1.5%.Smeared medicine of the present invention 1 year, the painful elimination of itching of cicatrix, the deliquescing that flattens is near skin color.
The patient, Liu XX, man, 15 years old, Hengshui City people.Facial skin-grafting back forms the contracture cicatrix, and its area is about 4X4 centimetre.Smeared medicine of the present invention after half a year 3 months, cicatrix is atrophy no longer, and the deliquescing that flattens in 15 months is near skin peptide color.
Embodiment 1
A) it is subsequent use to take by weighing each crude drug Radix Salviae Miltiorrhizae 40 grams, Flos Carthami 50 grams, Olibanum 35 grams, Carapax Trionycis 40 grams, Sanguis Draxonis 35 grams, Crinis Carbonisatus 35 grams, white beeswax 70 grams, Cera Flava 30 grams, 500 milliliters in Oleum Sesami.
B) with Radix Salviae Miltiorrhizae, Olibanum, the Flos Carthami decocte with water twice of said weight, add water at every turn and be not advisable to have medicine, decoct 1/4th of original water, merge decocting liquid twice.Cross and filter filtrating, at 60~70 ℃ of dry down dry extracts 1 of making.
C) Sanguis Draxonis with said weight proportion carries out reflux, extract, at 90~95% ethanol, with extracting the ethanol dry dry extracts 2 that get under 60~70 ℃ that reclaim.
D) Oleum Sesami of said weight proportion is endured to 200 ℃, added Carapax Trionycis, Crinis Carbonisatus boiled 15 minutes.It is cool to 80 ℃ to collect filtrate Oleum Sesami, adds the fine powder of white beeswax, Cera Flava, dry extract 1 and dry extract 2.With its even active component that makes medicine of the present invention that is in harmonious proportion.
Embodiment 2
A) take by weighing each material medicine: Radix Salviae Miltiorrhizae 40 restrains, Flos Carthami 50 restrains, Olibanum 35 restrains, Carapax Trionycis 40 restrains, Crinis Carbonisatus 35 restrains, Sanguis Draxonis 35 restrains, Hirudo 20 restrains, Calamina 15 restrains, 500 milliliters in Oleum Sesami is subsequent use.
B) Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Calamina, the Hirudo of said weight proportion added decocting and endure twice, each amount of water was not advisable to have medicine, decocted 1/4th of original water, merged decocting liquid twice.Cross and filter filtrating, at 60~70 ℃ of dry down dry extracts 1 of making.
C) Sanguis Draxonis of said weight proportion is added 90~95% ethanol and purifies, with extracting solution ethanol at 60~70 ℃ of exsiccant dry extracts 2 down.
D) Oleum Sesami of said weight proportion is endured to 200 ℃, added Carapax Trionycis, Crinis Carbonisatus fried 15 minutes.Collect and filter Oleum Sesami cold to 80 ℃, add the fine powder of white beeswax, Cera Flava, dry extract 1 and dry extract 2.With its even active ingredient that makes medicine of the present invention that is in harmonious proportion.

Claims (4)

1. medicine of treating cicatrix; It is characterized in that its crude drug is: 500 milliliters of Radix Salviae Miltiorrhizae 30~50 grams, Flos Carthami 40~60 grams, Olibanum 30~40 grams, Carapax Trionycis 30~45 grams, Crinis Carbonisatus 15~20 grams, Sanguis Draxonis 30~40 grams, white beeswax 60~75 grams, Cera Flava 25~35 grams, Hirudo 20~30 grams, Calamina 15~30 grams, Oleum Sesami.
2. according to the method for preparing of the said medicine of claim 1, it comprises the following steps:
A) take by weighing each crude drug: Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Carapax Trionycis, Crinis Carbonisatus, Sanguis Draxonis, Hirudo, Calamina, Oleum Sesami are subsequent use;
B) Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Calamina, the Hirudo of said weight proportion being added decocting endures twice; Each amount of water was not advisable to have medicine, fried in shallow oil 1/4th of original water, merged decocting liquid twice; Cross and filter filtrating, make dry extract 1 60~70 ℃ of following dryings;
C) Sanguis Draxonis of said weight proportion is added 90~95% ethanol and purifies, with extracting solution ethanol at 60~70 ℃ of dry down dry extracts 2;
D) Oleum Sesami of said weight proportion is endured to 200 ℃, added Carapax Trionycis, Crinis Carbonisatus fried 15 minutes, collect and filter Oleum Sesami cold to 80 ℃, add the fine powder of white beeswax, Cera Flava, dry extract 1 and dry extract 2, it evenly is in harmonious proportion the active ingredient that makes medicine of the present invention.
3. a medicine of treating cicatrix is characterized in that, its crude drug is: 500 milliliters of Radix Salviae Miltiorrhizae 40 grams, Flos Carthami 50 grams, Olibanum 35 grams, Carapax Trionycis 40 grams, Crinis Carbonisatus 35 grams, Sanguis Draxonis 35 grams, white beeswax 70 grams, Cera Flava 30 grams, Oleum Sesami.
4. according to the method for preparing of the said medicine of claim 3, it comprises the following steps:
A) take by weighing each crude drug: Radix Salviae Miltiorrhizae, Flos Carthami, Olibanum, Carapax Trionycis, Sanguis Draxonis, Crinis Carbonisatus, white beeswax, Cera Flava, Oleum Sesami are subsequent use;
B) with Radix Salviae Miltiorrhizae, Olibanum, the Flos Carthami decocte with water twice of said weight, add water at every turn and be not advisable to have medicine, decoct 1/4th of original water, merge decocting liquid twice.Cross and filter filtrating, make dry extract 1 60~70 ℃ of following dryings;
C) Sanguis Draxonis with said weight proportion carries out reflux, extract, at 90~95% ethanol, with extracting the ethanol dry dry extracts 2 that get under 60~70 ℃ that reclaim;
D) Oleum Sesami of said weight proportion is endured to 200 ℃, added Carapax Trionycis, Crinis Carbonisatus boiled 15 minutes.It is cool to 80 ℃ to collect filtrate Oleum Sesami, adds the fine powder of white beeswax, Cera Flava, dry extract 1 and dry extract 2; With its even active component that makes medicine of the present invention that is in harmonious proportion.
CN2009101692136A 2009-08-24 2009-08-24 Medicament for treating scar and preparation method thereof Expired - Fee Related CN101647920B (en)

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Application Number Priority Date Filing Date Title
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CN104758857A (en) * 2015-04-29 2015-07-08 赵振荣 Unguent for treating skin scar stasis toxin coalescence symptom and preparing method thereof

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