CN101647435A - Synthetical sterilization composition - Google Patents
Synthetical sterilization composition Download PDFInfo
- Publication number
- CN101647435A CN101647435A CN200910159605A CN200910159605A CN101647435A CN 101647435 A CN101647435 A CN 101647435A CN 200910159605 A CN200910159605 A CN 200910159605A CN 200910159605 A CN200910159605 A CN 200910159605A CN 101647435 A CN101647435 A CN 101647435A
- Authority
- CN
- China
- Prior art keywords
- metalaxyl
- zoxamide
- agent
- bactericidal composition
- control efficiency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a sterilization composition which is characterized by using zoxamide (A) as an effective component and using one (B) of the phenyl amide bactericides of metalaxyl, metalaxyl-m, benalaxyl, efficient benalaxyl and oxadixyl as another effective component, wherein the mass ratio of the effective component A and the effective component B is 50:1-1:80. The zoxamide has obvious synergetic effect by matching with any one of the phenyl amide bactericides according to a certain proportion and can be used for preventing and treating diseases on plants such as vegetables, fruit trees and grains, particularly oomycete disease.
Description
Technical field
The present invention relates to a kind of bactericidal composition, especially a kind of combination sterilization composition that contains zoxamide.
Background technology
The major measure of preventing and treating disease at present remains chemical control.Yet in recent years owing to single drug and other unscientific application method, various crop pathogen such as late disease bacteria, Pseudoperonospora cubensis etc. have produced resistance to some medicaments commonly used, become a great problem of chemical control.Germ develops immunity to drugs, and causes pharmacy control efficacy to descend, and the disease wildness causes drug cost to increase and increasing environmental pollution thereupon causing frequent dispenser again.According to the literature, late disease bacteria and Pseudoperonospora cubensis have produced resistance to medicaments such as metalaxyls.Therefore, the agriculture chemical compounding kind of development of new, to avoid germ to produce resistance, suspension of pesticide resistance generation speed and to prolong the service life of existing pesticide species resource and satisfy people, all significant to food security and the more and more higher requirement of living environment.
Zoxamide (Zoxamide) is a kind of acid amide fungicides of protectiveness efficiently, has long and good resistance of rainwater washing against performance of lasting period, and its mechanism of action uniqueness is by suppressing the sclerotium division in conjunction with tubulin β-subunit and destruction microtubule cytoskeleton.It is mainly used in prevents and treats Oomycete disease such as eqpidemic disease, downy mildew, also effective to gray mold, powdery mildew.But its use cost height.
Summary of the invention
The purpose of this invention is to provide a kind of efficient, environmental protection and help the combination sterilization composition that contains zoxamide of germ resistance management.
Combination sterilization composition of the present invention, it is characterized in that with zoxamide (A) be an active ingredient, with phenylamide fungicide metalaxyl, Metalaxyl-M, M 9834, efficient M 9834 with a kind of (B) in the spirit of Evil frost is another active ingredient, the mass ratio of A and B is 50: 1～1: 80, and all the other are to allow in the agricultural chemicals to use and the acceptable auxiliary element.
As a kind of formulation optimization of the present invention, the mass ratio of effective constituents A and B is preferred 10: 1～1: 20 in the described bactericidal composition.
Phenyl amide series bactericidal agent of the present invention is specially:
Metalaxyl (Metalaxyl), Metalaxyl-M (Metalaxyl-M), M 9834 (Benalaxyl) ， Evil frost spirit (Oxadixyl), or, efficient M 9834 (Benalaxyl-M).
Above-mentioned active component all is bactericide well known in the art, can buy by various commercial channel.
Except active component zoxamide and phenyl amide series bactericidal agent, comprise also in the bactericidal composition of the present invention that auxiliary agent such as solvent, dispersant, emulsifier, stabilizing agent, antifreezing agent, wetting agent and other are of value to the known substance of active ingredient stable and drug effect performance in preparation, all be the various compositions of using or allow use in the pesticidal preparations always, be not particularly limited, concrete composition and consumption require to determine by simple experiment according to prescription.
Bactericidal composition of the present invention can be prepared into known method and be fit to any one formulation that agricultural is used, and reasonable formulation is wetting powder, missible oil, suspending agent, water dispersible granules, aqueous emulsion and microemulsion.
Product described in the invention (composition) can the finished product preparation form provide, and promptly each material mixes in the composition, and the composition of composition also can provide with single agent form, directly directly mixes in bucket or jar before the use, is diluted to required concentration then.
Bactericidal composition of the present invention can be used to prevent and treat the disease on the various crop such as cereal class, vegetables, cotton, fruit tree, is particularly useful for preventing and treating the oomycetes disease.
Composition of the present invention can be used by common method, and as cast, seed dressing, spraying, dusting or be fuming, its amount of application is with weather condition or crop state variation.
Compared with prior art, beneficial effect of the present invention is: 1. composition is made up of two kinds of different active ingredients of mechanism of action, have obvious role in synergism with certain proportion after composite, improved control efficiency, also help overcoming simultaneously and delay the drug-fast generation of germ; 2. medicament is mixed and has reduced dosage, thereby has reduced cost and the pollution that has alleviated environment.
Embodiment
The active ingredient of different agricultural chemicals is made up, and is a kind of mode effectively and efficiently of avoiding that phytopathogen produces that resistance and delaying drug resistance produce speed.By test, screening obtains compound synergic and well fills a prescription, and not only can obviously improve actual control efficiency, reduces the usage amount of agricultural chemicals, also helps to delay the drug-fast generation speed of germ.
The inventor is by a large amount of tests that is mixed, find that the combination of zoxamide and a kind of selected phenyl amide series bactericidal agent has remarkable role in synergy to Pseudoperonospora cubensis and late disease bacteria, and be not only the simple addition of two kinds of medicaments, specifically describe with following biologicall test example.
Biologicall test example 1: the composite Toxicity Determination of zoxamide and metalaxyl to cucumber downy mildew
Subjects: the bacterium of downy mildew of cucumber (Pseudoperonospora cubensis) that picks up from the field
Test method: with reference to " the agricultural industry criteria NY/T1156.7-2006 of the People's Republic of China (PRC) ", pot-culture method.Dip in the sporangium that the distilled water of getting about 10 ℃ washes the cucumber leaves back side that has Pseudoperonospora cubensis of picking up from the field with writing brush, be made into 3 * 10
5The suspension of individual sporangium/mL.Choose two leaf period cucumber seedlings of growing way unanimity, each processing selects for use 5 basins for examination melon seedling, sprays the about 5mL soup of every processing under 50PSI pressure with the Potter spray tower.Each medicament is provided with 5 concentration gradients, is blank with what spray the equivalent clear water.24h spray inoculation bacterium of downy mildew of cucumber after the chemicals treatment, place climatic cabinate (relative moisture 100%, temperature 15-20 ℃) to cultivate cucumber seedling after the inoculation, keep 15-24 ℃ of temperature, relative moisture about 90% to preserve moisture and bring out behind the 24h, 5d " Invest, Then Investigate " disease index, and calculate control efficiency.
Control efficiency is converted into probability value (y), and liquor strength (μ g/ml) converts logarithm value (x) to, calculates concentration EC in virulence equation and the inhibition with method of least squares
50, according to the toxicity index and the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun medicament.
Actual measurement toxicity index (ATI)=(standard medicament EC
50/ reagent agent EC
50) * 100
The percentage composition of B in percentage composition+B medicament toxicity index * mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (the ATI)/theoretical toxicity index (TTI) of mixture] * 100
When CTC≤80, then the composition performance is for antagonism, and when 80＜CTC＜120, then the composition performance is for summation action, and when CTC 〉=120, then the composition performance is synergistic effect.Toxicity test the results are shown in Table 1.
Measurement result (table 1) shows that zoxamide and metalaxyl have synergistic effect to bacterium of downy mildew of cucumber between proportioning 50: 1～1: 80, and especially between 10: 1～1: 20, synergistic effect is obvious, and co-toxicity coefficient is more than 170.
The composite pot experiment measurement result of table 1 zoxamide and metalaxyl to bacterium of downy mildew of cucumber
| Handle | ??EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| Metalaxyl | ??51.24 | ??100.0 | ||
| Zoxamide | ??1.36 | ??3767.6 | ||
| Zoxamide 50: metalaxyl 1 | ??24.57 | ??208.5 | ??171.9 | ??121.3 |
| Zoxamide 30: metalaxyl 1 | ??16.78 | ??305.4 | ??218.3 | ??139.9 |
| Zoxamide 10: metalaxyl 1 | ??6.77 | ??756.9 | ??433.4 | ??174.6 |
| Zoxamide 3: metalaxyl 1 | ??2.31 | ??2218.2 | ??1016.9 | ??218.1 |
| Zoxamide 1: metalaxyl 1 | ??1.25 | ??4099.2 | ??1933.8 | ??212.0 |
| Zoxamide 1: metalaxyl 6 | ??0.81 | ??6325.9 | ??3243.7 | ??195.0 |
| Zoxamide 1: metalaxyl 10 | ??0.81 | ??6325.9 | ??3434.2 | ??184.2 |
| Zoxamide 1: metalaxyl 20 | ??0.83 | ??6173.5 | ??3593.0 | ??171.8 |
| Zoxamide 1: metalaxyl 40 | ??1.05 | ??4880.0 | ??3678.2 | ??132.7 |
| Zoxamide 1: metalaxyl 80 | ??1.14 | ??4494.7 | ??3722.4 | ??120.7 |
Metalaxyl in the top example can replace with M 9834, between proportioning 50: 1～1: 80, bacterium of downy mildew of cucumber is had synergistic effect, and co-toxicity coefficient all more than 120, sees Table 2.
The composite pot experiment measurement result of table 2 zoxamide and M 9834 to bacterium of downy mildew of cucumber
| Handle | EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| M 9834 | ??35.04 | ??100.0 | ||
| Zoxamide | ??1.36 | ??2576.5 |
| Zoxamide 50: M 9834 1 | ??19.24 | ??182.1 | ??148.6 | ??122.6 |
| Zoxamide 30: M 9834 1 | ??14.23 | ??246.2 | ??179.9 | ??136.9 |
| Zoxamide 10: M 9834 1 | ??6.09 | ??575.4 | ??325.1 | ??177.0 |
| Zoxamide 3: M 9834 1 | ??2.34 | ??1497.4 | ??719.1 | ??208.2 |
| Zoxamide 1: M 9834 1 | ??1.21 | ??2895.9 | ??1338.2 | ??216.4 |
| Zoxamide 1: M 9834 6 | ??0.78 | ??4492.3 | ??2222.7 | ??202.1 |
| Zoxamide 1: M 9834 10 | ??0.80 | ??4380.0 | ??2351.3 | ??186.3 |
| Zoxamide 1: M 9834 20 | ??0.81 | ??4325.9 | ??2458.5 | ??176.0 |
| Zoxamide 1: M 9834 40 | ??0.99 | ??3539.4 | ??2516.1 | ??140.7 |
| Zoxamide 1: M 9834 80 | ??1.11 | ??3156.8 | ??2545.9 | ??124.0 |
Biologicall test example 2: the composite Toxicity Determination of zoxamide and Metalaxyl-M to the tomato late blight bacterium
Subjects: the tomato late blight bacterium (Phytophthora infestans) of picking up from the field
Test method: with reference to " the agricultural industry criteria NY/T1156.2-2006 of the People's Republic of China (PRC) ", the mycelial growth rate method.The tomato late blight bacterium is used the PDA medium culture, when treating that bacterium colony has just covered with culture dish, is that the card punch of 7mm punches from the edge with internal diameter, and the mycelia piece that breaks into is as inoculum.Get the soup 5mL for preparing and quantitative 75mL sterilising medium respectively and mix, make 4 pastille flat boards, be mixed into contrast with equivalent sterile water and medium.The inversion of mycelia piece is connected to dull and stereotyped central authorities, and in 28 ℃ of incubators, cultivates.Behind the 7d, measure colony diameter, calculate and respectively handle the clean amount of growth of colony diameter, mycelial growth inhibition rate with the right-angled intersection method.
Clean amount of growth (mm)=measurement colony diameter-7
Mycelial growth inhibition rate (%)=[(the clean amount of growth of the clean amount of growth-processed group of control group)/clean amount of growth of control group] * 100
Mycelial growth inhibition rate is converted into probability value (y), and liquor strength (μ g/ml) converts logarithm value (x) to, calculates concentration EC in virulence equation and the inhibition with method of least squares
50, according to the toxicity index and the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun medicament.Toxicity test the results are shown in Table 3.
Result's (table 3) shows that zoxamide and Metalaxyl-M have synergistic effect to the tomato late blight bacterium between proportioning 50: 1～1: 80, and especially between 10: 1～1: 20, co-toxicity coefficient is more than 180.
The composite Toxicity Determination result of table 3 zoxamide and Metalaxyl-M to the tomato late blight bacterium
| Handle | ??EC 50(μg/mL) | ??ATI | ??TTI | Co-toxicity coefficient CTC |
| Metalaxyl-M | ??12.28 | ??100.0 | ||
| Zoxamide | ??1.22 | ??1006.6 | ||
| Zoxamide 50: Metalaxyl-M 1 | ??8.54 | ??143.8 | ??117.8 | ??122.1 |
| Zoxamide 30: Metalaxyl-M 1 | ??7.11 | ??172.7 | ??129.2 | ??133.6 |
| Zoxamide 10: Metalaxyl-M 1 | ??3.55 | ??345.9 | ??182.4 | ??189.6 |
| Zoxamide 3: Metalaxyl-M 1 | ??1.85 | ??663.8 | ??326.6 | ??203.2 |
| Zoxamide 1: Metalaxyl-M 1 | ??0.98 | ??1253.1 | ??553.3 | ??226.5 |
| Zoxamide 1: Metalaxyl-M 6 | ??0.65 | ??1889.2 | ??877.0 | ??215.4 |
| Zoxamide 1: Metalaxyl-M 10 | ??0.68 | ??1805.9 | ??924.1 | ??195.4 |
| Zoxamide 1: Metalaxyl-M 20 | ??0.69 | ??1779.7 | ??963.4 | ??184.7 |
| Zoxamide 1: Metalaxyl-M 40 | ??0.88 | ??1395.5 | ??984.4 | ??141.8 |
| Zoxamide 1: Metalaxyl-M 80 | ??1.02 | ??1203.9 | ??995.4 | ??121.0 |
Composition pesticide of the present invention can be prepared into known method and be fit to any one formulation that agricultural is used, and reasonable formulation is wetting powder, missible oil, suspending agent, water dispersible granules, aqueous emulsion and microemulsion.
In order to make purpose of the present invention, technical scheme and advantage clearer, the present invention describes with following specific embodiment, but the present invention is limited to these examples absolutely not.The following stated only is the present invention embodiment preferably, only in order to explain the present invention, can not therefore be interpreted as the restriction to claim of the present invention.Should be pointed out that all any modifications of being made within the spirit and principles in the present invention, be equal to replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.Percentage all is weight percentage in all prescriptions.The processing technology of the various preparations of the present composition is prior art, can change to some extent according to different situations.
The related activity composition that relates in following examples is the former medicine of 98% zoxamide, the former medicine of 98% metalaxyl, the former medicine of 90% Metalaxyl-M, the former medicine of 96% M 9834 and the clever former medicine of 96% Evil frost.
Embodiment 1:51% zoxamide metalaxyl wetting powder
Zoxamide 51.02g
Metalaxyl 1.02g
Lauryl sodium sulfate (wetting agent) 2g
Sodium lignin sulfonate (dispersant) 5g
White carbon black (filler) 10g
Kaolin (filler) complements to 100g.
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, after ultrafine crusher is pulverized, promptly get 51% zoxamide metalaxyl wetting powder.
Metalaxyl in the present embodiment is replaceable to be phenyl amide series bactericidal agents such as Metalaxyl-M, M 9834, efficient M 9834 and the spirit of Evil frost, forms new embodiment.
This embodiment is applied to prevent and treat cucumber downy mildew.51% zoxamide metalaxyl wetting powder is pressed the spraying of 200ga.i./ha thin up, and 7 days control efficiency is 92.8% behind the medicine.200ga.i./ha pressed by 24% zoxamide suspending agent and 25% metalaxyl wetting powder is pressed 1500g a.i./ha, the thin up spraying, and 7 days control efficiency is respectively 88.4% and 78.5% behind the medicine.The synergistic effect of the composite back of zoxamide and metalaxyl is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the control efficiency of cucumber downy mildew, thereby has reduced cost and alleviated pollution to environment.
Embodiment 2:62% zoxamide Metalaxyl-M water dispersible granules
Zoxamide 61.22g
Metalaxyl-M 2.22g
Negel (dispersant) 5g
Sodium lignin sulfonate (dispersant) 7g
Lauryl sodium sulfate (wetting agent) 2g
Ammonium sulfate (disintegrant) 5g
Precipitated calcium carbonate (filler) complements to 100g.
Active component, dispersant, wetting agent, disintegrant and the filler ratio in prescription is mixed, become wetting powder through comminution by gas stream, add a certain amount of water mixing extruding again and make material, obtain 62% zoxamide Metalaxyl-M water-dispersible granules after the drying screening.
Metalaxyl-M in the present embodiment is replaceable to be phenyl amide series bactericidal agents such as metalaxyl, M 9834, efficient M 9834 and the spirit of Evil frost, forms new embodiment.
This embodiment is applied to prevent and treat downy mildew of garpe.62% zoxamide Metalaxyl-M water-dispersible granules is pressed the spraying of 150g a.i./ha thin up, and 7 days control efficiency is 93.7% behind the medicine.150g a.i./ha pressed by 24% zoxamide suspending agent and 12% Metalaxyl-M wetting powder is pressed 600g a.i./ha, the thin up spraying, and 7 days control efficiency is respectively 88.7% and 84.3% behind the medicine.The synergistic effect of the composite back of zoxamide and Metalaxyl-M is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the control efficiency of downy mildew of garpe.
Embodiment 3:33% zoxamide M 9834 suspending agent
Zoxamide 30.61g
M 9834 3.13g
Methyl naphthalene sulfonate formaldehyde condensate (wetting dispersing agent) 6g
Xanthans (thickener) 2g
Bentonite (thickener) 1g
Glycerine (antifreeze) 5g
Water complements to 100g.
The ratio of each component such as active component, wetting agent, dispersant, thickener, antifreeze and water in prescription mixed, after grinding and/or high speed shear, obtain 33% zoxamide M 9834 suspending agent.
M 9834 in the present embodiment is replaceable to be phenyl amide series bactericidal agents such as metalaxyl, Metalaxyl-M, efficient M 9834 and the spirit of Evil frost, forms new embodiment.
This embodiment is applied to prevent and treat tomato late blight.33% zoxamide M 9834 suspending agent is pressed the spraying of 200g a.i./ha thin up, and 7 days control efficiency is 95.8% behind the medicine.200g a.i./ha pressed by 24% zoxamide suspending agent and 25% M 9834 wetting powder is pressed 1500g a.i./ha, the thin up spraying, and 7 days control efficiency is respectively 90.3% and 80.5% behind the medicine.The synergistic effect of the composite back of zoxamide and M 9834 is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the control efficiency of tomato late blight.
Embodiment 4:8% zoxamide metalaxyl aqueous emulsion
Zoxamide 6.12g
Metalaxyl 2.04g
N-Methyl pyrrolidone (solvent) 10g
Calcium dodecyl benzene sulfonate (emulsifier) 5g
Farming newborn 600# (emulsifier) 5g
Water complements to 100g.
Former medicine, solvent, emulsifier are added together, make and be dissolved into even oil phase; With water-soluble component and the mixed water that gets of water; Under high-speed stirred, oil phase is mixed with water, make 8% zoxamide metalaxyl aqueous emulsion.
Metalaxyl in the present embodiment is replaceable to be phenyl amide series bactericidal agents such as Metalaxyl-M, M 9834, efficient M 9834 and the spirit of Evil frost, forms new embodiment.
This embodiment is applied to prevent and treat potato late blight.8% zoxamide metalaxyl aqueous emulsion is pressed the spraying of 200ga.i./ha thin up, and 7 days control efficiency is 94.9% behind the medicine.200ga.i./ha pressed by 24% zoxamide suspending agent and 25% metalaxyl wetting powder is pressed 1500g a.i./ha, the thin up spraying, and 7 days control efficiency is respectively 88.8% and 82.5% behind the medicine.The synergistic effect of the composite back of zoxamide and metalaxyl is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the control efficiency of potato late blight, thereby has reduced cost and alleviated pollution to environment.
Embodiment 5:15% zoxamide Metalaxyl-M microemulsion
Zoxamide 7.65g
Metalaxyl-M 8.33g
N-Methyl pyrrolidone (solvent) 10g
Isopropyl alcohol (solvent) 15g
Farming newborn 600# (emulsifier) 5g
Farming newborn 1601# (emulsifier) 5g
Water complements to 100g.
Former medicine, solvent, emulsifier are added together, make and be dissolved into even oil phase; With water-soluble component and the mixed water that gets of water; Under high-speed stirred, oil phase is mixed with water, make 15% zoxamide Metalaxyl-M microemulsion.
Metalaxyl-M in the present embodiment is replaceable to be phenyl amide series bactericidal agents such as metalaxyl, M 9834, efficient M 9834 and the spirit of Evil frost, forms new embodiment.
This embodiment is applied to prevent and treat peronophythora litchi.15% zoxamide Metalaxyl-M microemulsion is pressed the spraying of 200ga.i./ha thin up, and 7 days control efficiency is 95.6% behind the medicine.200ga.i./ha pressed by 24% zoxamide suspending agent and 12% Metalaxyl-M wetting powder is pressed 600g a.i./ha, the thin up spraying, and 7 days control efficiency is respectively 89.7% and 83.8% behind the medicine.The synergistic effect of the composite back of zoxamide and Metalaxyl-M is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the control efficiency of peronophythora litchi, thereby has reduced use cost and alleviated pollution to environment.
Embodiment 6:21% zoxamide metalaxyl missible oil
Zoxamide 3.06g
Metalaxyl 18.37g
N-Methyl pyrrolidone (cosolvent) 10g
Farming newborn 1601# (emulsifier) 5g
Farming newborn 500# (emulsifier) 5g
Dimethylbenzene (solvent) complements to 100g.
Active component, emulsifier and the auxiliary agent ratio in prescription is added in the mixing kettle successively, stir, make 21% zoxamide metalaxyl missible oil.
Metalaxyl in the present embodiment is replaceable to be phenyl amide series bactericidal agents such as Metalaxyl-M, M 9834, efficient M 9834 and the spirit of Evil frost, forms new embodiment.
This embodiment is applied to prevent and treat the cotton eqpidemic disease.21% zoxamide metalaxyl missible oil is pressed the spraying of 500g a.i./ha thin up, and 7 days control efficiency is 93.6% behind the medicine.250g a.i./ha pressed by 24% zoxamide suspending agent and 25% metalaxyl wetting powder is pressed 2000g a.i./ha, the thin up spraying, and 7 days control efficiency is respectively 89.1% and 81.5% behind the medicine.The synergistic effect of the composite back of zoxamide and metalaxyl is obvious, to the control efficiency of cotton eqpidemic disease significantly better than single agent; Because the pharmacy effect raising obviously reduces when the amount ratio of active ingredient uses separately in the compound drug, thereby also alleviated pollution to environment.
The clever suspending agent of embodiment 7:42% benzoyl Jun An Evil frost
Zoxamide 2.04g
The clever 41.67g of Evil frost
Methyl naphthalene sulfonate formaldehyde condensate (wetting dispersing agent) 6g
Xanthans (thickener) 2g
Bentonite (thickener) 1g
Glycerine (antifreeze) 5g
Water complements to 100g.
The ratio of each component such as active component, wetting agent, dispersant, thickener, antifreeze and water in prescription mixed, after grinding and/or high speed shear, obtain the clever suspending agent of 42% benzoyl Jun An Evil frost.
Evil frost spirit in the present embodiment is replaceable to be phenyl amide series bactericidal agents such as Metalaxyl-M, M 9834, efficient M 9834 and metalaxyl, forms new embodiment.
This embodiment is applied to prevent and treat cauliflower downy mildew.The clever suspending agent of 42% benzoyl Jun An Evil frost is pressed the spraying of 450ga.i./ha thin up, and 7 days control efficiency is 93.1% behind the medicine.200ga.i./ha pressed by 24% zoxamide suspending agent and the clever wetting powder of 25% Evil frost is pressed 1500g a.i./ha, the thin up spraying, and 7 days control efficiency is respectively 88.3% and 80.5% behind the medicine.Zoxamide is Yu the composite back synergistic effect of Evil frost spirit is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the control efficiency of cauliflower downy mildew, thereby reduced use cost and alleviated pollution to environment.
Embodiment 8:81% zoxamide Metalaxyl-M wetting powder
Zoxamide 1.02g
Metalaxyl-M 88.89g
Lauryl sodium sulfate (wetting agent) 2g
Sodium lignin sulfonate (dispersant) 5g
White carbon black (filler) 10g
Kaolin (filler) complements to 100g.
Active component, various auxiliary agent and filler etc. are fully mixed in the ratio of prescription, after ultrafine crusher is pulverized, promptly get 81% zoxamide Metalaxyl-M wetting powder.
Metalaxyl-M in the present embodiment is replaceable to be phenyl amide series bactericidal agents such as metalaxyl, M 9834, efficient M 9834 and the spirit of Evil frost, forms new embodiment.
This embodiment is applied to prevent and treat capsicum epidemic disease.81% zoxamide Metalaxyl-M wetting powder is pressed the spraying of 600ga.i./ha thin up, and 7 days control efficiency is 90.8% behind the medicine.200ga.i./ha pressed by 24% zoxamide suspending agent and 12% Metalaxyl-M wetting powder is pressed 1000g a.i./ha, the thin up spraying, and 7 days control efficiency is respectively 88.4% and 81.5% behind the medicine.The synergistic effect of the composite back of zoxamide and Metalaxyl-M is obvious, and significantly better than single agent, and the consumption of active ingredient obviously reduces to the control efficiency of capsicum epidemic disease, thereby has reduced cost and alleviated pollution to environment.
Claims (7)
1, a kind of bactericidal composition is characterized in that: its active ingredient is zoxamide (A) and a kind of phenyl amide series bactericidal agent (B).
2, according to claim 1, it is characterized in that: described phenyl amide series bactericidal agent is a kind of in metalaxyl, Metalaxyl-M, M 9834, efficient M 9834 and the spirit of Evil frost.
3, bactericidal composition according to claim 1 and 2 is characterized in that: the mass ratio of effective constituents A and B is 50: 1～1: 80.
4, bactericidal composition according to claim 3 is characterized in that: the mass ratio of effective constituents A and B is 10: 1～1: 20.
5, bactericidal composition according to claim 1 and 2 is characterized in that: the formulation of described bactericidal composition is wetting powder, suspending agent, missible oil, aqueous emulsion, microemulsion and water dispersible granules.
6, the described bactericidal composition of claim 1, the application on control of crop disease.
7, the application of bactericidal composition according to claim 6 is characterized in that: described disease is the oomycetes disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910159605A CN101647435A (en) | 2009-07-21 | 2009-07-21 | Synthetical sterilization composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910159605A CN101647435A (en) | 2009-07-21 | 2009-07-21 | Synthetical sterilization composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101647435A true CN101647435A (en) | 2010-02-17 |
Family
ID=41669848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200910159605A Pending CN101647435A (en) | 2009-07-21 | 2009-07-21 | Synthetical sterilization composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101647435A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104710024A (en) * | 2013-12-11 | 2015-06-17 | 中国石油化工股份有限公司 | Phosphorus-free water treatment agent composition and application thereof |
| CN104738078A (en) * | 2015-03-25 | 2015-07-01 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Bactericidal composition containing zoxamide and silthiopham |
| CN106035379A (en) * | 2016-06-27 | 2016-10-26 | 中国烟草总公司郑州烟草研究院 | Bactericide composition containing phenylamide and benzamide bactericides and biocontrol bacterium, preparation and applications |
-
2009
- 2009-07-21 CN CN200910159605A patent/CN101647435A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104710024A (en) * | 2013-12-11 | 2015-06-17 | 中国石油化工股份有限公司 | Phosphorus-free water treatment agent composition and application thereof |
| CN104710024B (en) * | 2013-12-11 | 2017-04-26 | 中国石油化工股份有限公司 | Phosphorus-free water treatment agent composition and application thereof |
| CN104738078A (en) * | 2015-03-25 | 2015-07-01 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Bactericidal composition containing zoxamide and silthiopham |
| CN106035379A (en) * | 2016-06-27 | 2016-10-26 | 中国烟草总公司郑州烟草研究院 | Bactericide composition containing phenylamide and benzamide bactericides and biocontrol bacterium, preparation and applications |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102172240B (en) | A kind of bactericidal composition containing benziothiazolinone and methoxy acrylic bactericide | |
| CN101642126B (en) | Compound bactericidal composition containing fludioxonil | |
| CN101595882B (en) | Pesticide composition containing methoxyl acrylic ester bactericide | |
| CN101690480B (en) | Pesticide composition containing methoxy acrylic bactericide and application thereof | |
| CN101690483B (en) | Bactericidal composition containing triazole class compounds | |
| CN101653118B (en) | Compound synergistic bactericidal composition | |
| CN101595887A (en) | A kind of bactericidal composition that contains Prochloraz | |
| CN101617657A (en) | Pesticide composition | |
| CN101647441B (en) | Sterilization combination containing azoxystrobin and application thereof | |
| CN101658177A (en) | Complex bactericidal composition containing cyazofamid | |
| CN101642104A (en) | Sterilization composition containing fenoxanil | |
| CN102630679A (en) | Pesticide composition containing orysastrobin | |
| CN101642120A (en) | Pesticide composition containing dyson fungicides | |
| CN101595889A (en) | A kind of bactericidal composition that contains iprodione | |
| CN101647451A (en) | Sterilization combination containing cyazofamid | |
| CN101669485B (en) | Compound bactericidal composition containing fludioxonil | |
| CN101658175A (en) | Pesticide composition and application thereof | |
| CN101647435A (en) | Synthetical sterilization composition | |
| CN101653128A (en) | Bactericidal composition containing dimethomorph | |
| CN103190420B (en) | Propiconazole-containing bactericidal composition | |
| CN101669495A (en) | Bactericidal composition containing kresoxim-methyl phenylate | |
| CN101627770A (en) | Sterilizing composition | |
| CN102972410A (en) | Pesticide composition containing prothioconazole and methoxyl acrylic ester bactericides | |
| CN101647447B (en) | Sterilizing composition | |
| CN101849546A (en) | Pesticide composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100217 |