CN101642530B - Externally applied ointment for treating surgery diseases and preparation method thereof - Google Patents

Externally applied ointment for treating surgery diseases and preparation method thereof Download PDF

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CN101642530B
CN101642530B CN2008101460651A CN200810146065A CN101642530B CN 101642530 B CN101642530 B CN 101642530B CN 2008101460651 A CN2008101460651 A CN 2008101460651A CN 200810146065 A CN200810146065 A CN 200810146065A CN 101642530 B CN101642530 B CN 101642530B
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diseases
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冀长杰
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Abstract

The invention relates to externally applied ointment for treating skin ulceration diseases and a preparation method thereof. The medicament is prepared from rosin, sesame oil, bees wax, frankincense powder, myrrh powder, Japanese ampelopsis root, bletilla, Indian iphigenia bulb, heartleaf houttuynia herb, lightyellow sophora root and densefruit pittany root-bark in a certain weight ratio. The preparation method for the medicament comprises the following steps: in the eleven Chinese medicinal herbs, soaking seven Chinese medicaments of the sesame oil, the Japanese ampelopsis root, the bletilla, the Indian iphigenia bulb, the heartleaf houttuynia herb, the lightyellow sophora root and the densefruit pittany root-bark in the ratio in a pan together at normal temperature, soaking for seven days if in winter, and soaking for three days if in summer; and then decocting the seven soaked Chinese medicaments with fire until decoction is slightly dry, removing dregs in the decoction for filtration, then putting the rosin and the bees wax in the ratio, after fully dissolving the rosin and the bees wax, removing the fire, putting the frankincense powder and the myrrh powder when the temperature is reduced to 40 DEG C, fully stirring, and cooling thoroughly into the ointment. The ointment has obvious curative effect on skin and flesh fester, skin and external diseases and virus infection caused by external injuries, diabetic foot induced by diabetes and other diseases.

Description

A kind of external-applied ointment for the treatment of surgical diseases and preparation method thereof
[technical field] the present invention relates to a kind of external used medicine for the treatment of surgical diseases, specifically a kind ofly treat that the skin and flesh that external injury causes festers, the external-applied ointments such as diabetic foot of suppuration, skin infection (skin infection comprises facial area furuncle, hard furuncle on hand and foot, acute superficial lymphangitis, gas gangrene, cutaneous anthrax, below omits) viral infection diabetes-induced.
[background technology] existing " loose liana removing toxic substances and promoting tissue regeneration ointment " is my secret prescription handed down in the family from generation to generation pure Chinese medicinal preparation, is raw material with natural Chinese medicine, and the medicine source is extensive, and raw material is easy to get, no side effects, and clinical efficacy is remarkable, executes with this medicine that to control above-mentioned disease well received.But in clinical use for many years, find to cause that in the treatment wound abnormal phenomenas such as pimple, vesicle, pruritus appearred in disease processes such as skin and flesh festers, suppuration, skin infection.Through looking in October, 1980 second edition " the 40th page of record of the clinical handbook of surgery of Chinese medicine of Gu Baihua chief editor
" skin infection uses plaster may cause the red or pimpling of Ju portion Pi Fu inflammation sometimes or vesicle takes place, very then wet phenomenon such as mashed, and this is because due to the skin allergy, forms contact dermatitis from plaster, all this kind situations can be used ointment instead." but " loose liana Myogenic ointment of of removing toxic substances " itself is exactly ointment, executes when controlling clinical, the contact dermatitis from plaster phenomenon still occurred.
[summary of the invention] the objective of the invention is to provide in order to overcome above-mentioned technical deficiency a kind of and reaches and suppress and a kind of surgical diseases external-applied ointments such as the skin and flesh that the treatment wound of drug effect causes festers, suppuration, skin infection, the sick foot of viral infection and preparation method thereof take place obviously to strengthen simultaneously prevention contact dermatitis from plaster phenomenon by increasing Radix Sophorae Flavescentis, Cortex Dictamni two herbal medicines.
The present invention be address the above problem the scheme that is adopted be the design a kind of external-applied ointment for the treatment of surgical diseases, this medicine by following ten simply Chinese herbal medicine be that raw material is made (weight) according to a certain weight ratio
Figure GSB00000516640100021
The preparation method of medicine of the present invention is:
At first the Oleum Sesami in the Chinese herbal medicine, Radix Ampelopsis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Pseudobulbus cremastrae seu pleiones, Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Dictamni seven flavor Chinese medicines are together put into pot in proportion and are soaked at normal temperatures simply with ten, soaked winter seven, soaked summer three, then soaked seven flavor Chinese medicines are lit a fire and boil, wait to boil littlely witheredly put into Colophonium immediately in proportion after going short, bristly hair or beard to filter medicinal liquid, Cera Flava is treated fully to dissolve recession from burning things which may cause a fire disaster, when temperature is reduced to 40 ℃, put into Olibanum, Myrrha fully stir cool completely into cream medicine of the present invention, last sterilization packaging gets final product.
Pharmaceutical dosage form of the present invention is a unguentum.Character is yellow, bitter in the mouth, is slightly cold.
Packing specification, getting the flexible flexible plastic of 2 millimeters thick, to make diameter be 45 millimeters, long, 130 millimeters drum, outer vent is made long 10 millimeters, wide 5 millimeters, high 12 millimeters long square cylinders, outer vent is rectangle, extrude mastic and be flat, cover and be buckle closure, by the paste filling machine ointment of packing into, every barrel is 80 grams, stifled with heat-sealing machine sealing back then.Standby behind the sterilization in 15 ℃ of preservations above freezing.During use, after the sterilization of skin ulcer face, ointment is squeezed on the skin ulcer face, thickness is advisable at the 3-4 millimeter, gauze wrapping, immobilization with adhesive tape.Heavy patient changed dressings once in 8 hours, and light patient changed dressings once in 24 hours.The patient of this medicine of application, fasting maror during medication.
Medicine of the present invention has heat-clearing and toxic substances removing, the heat clearing and damp drying evacuation of pus of drawing out pus by applying a plaster to the affected part, dispersing swelling and dissipating binds, putrefaction-removing granulation-promoting, pain relieving, analgesic therapy, blood circulation promoting and blood stasis dispelling, blood circulation promoting, accelerate effects such as ulcer surface reparation, particularly external injury is caused skin and flesh fester suppuration, skin infection, the skin and flesh such as diabetic foot of the viral infection diabetes-induced disease of festering has significant curative effect.
Clinical drug case observation therapeutic effect of the present invention:
Above disease belongs to the category of motherland's medical science surgical diseases
1, paathogenic factor: the evil poison of (1) diseases caused by exogenous pathogenic factor six climate exopathogens; (2) the special evil poison of impression; (3) external injury; (4) feelings will internal injury; (5) diet is not understood.
2, cause of disease mechanism: (1) function is not normal; (2) coagulation of QI-blood; (3) meridians block.
The thousands of examples of the above-mentioned sufferer of Drug therapy of the present invention, select 194 examples and treat group and compare with matched group, wherein external injury causes that skin and flesh festers, suppuration patient 102 examples, skin infection patient 60 examples, viral infection diabetes, patient with diabetic feet 32 examples of bringing out.
Through contrasting and statistical procedures, prove that it is evident in efficacy through clinical observation with matched group, existing that the clinical case visual report is as follows;
One, clinical data: outpatient service is made a definite diagnosis, external injury causes that skin and flesh festers, the diabetic foot of suppuration, skin infection, viral infection diabetes-induced, and the patient amounts to 194 examples, and the man is more than the woman, and the age, 45 years old mean age, various diseases were divided into two groups in 20-70 year.
Medicine of the present invention is the treatment group: various sick 97 examples
With western medicine is matched group: various sick 97 examples
1, cause skin and flesh fester suppuration, skin infection with western medicine, external injury, give anti-infectives, antibiotics, sulfonamides, vitamin B, C etc., external rivanol gauze wrapping skin ulcer face is treated.
2, medicine Main Ingredients and Appearance of the present invention: Colophonium, Oleum Sesami, Cera Flava, Olibanum, Myrrha, Radix Ampelopsis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Pseudobulbus cremastrae seu pleiones, Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Dictamni ten Chinese herbal medicine are simply formed, and boil through high temperature sterilize and form pure Chinese medicine unguentum.
According to the medication of skin ulcer face size, thickness 3-4 millimeter is advisable and is applied on the skin ulcer face during clinical practice, and 10 days is a course of treatment, observes therapeutic effect 1-2 the course of treatment, observes 30 days time limits.
Observational technique: index and curative effect judging standard, observe indexs such as patient's symptom and sign weekly, curative effect is divided into: effectively, produce effects, recovery from illness, invalid level Four, recovery from illness with effectively add up to effectively.
After the medication, pus is excessive more, and congestion and swelling pain gradually gently is effective.Redness disappears, and pus rareness, slough hold in the palm outward, pain disappears is produce effects.No congestion and swelling pain does not have pus, granulation, skin ulcer face calm down for the recovery from illness, with the subjective symptoms no change, the skin ulcer face do not have change into invalid.
3, the results are shown in Table:
Figure GSB00000516640100041
As can be seen from the table, treatment group and matched group exist significant difference, and medication therapy groups produce effects of the present invention is fast, and curative effect is good, is better than matched group, western medicine.
4, model case: (three kinds of diseases are a case each)
Good fortune is closed strange: the man, and 28 years old, Zhejiang Yong Jiaxian people, examine private prosecution May 2 calendar year 2001: do woodwork, by electric saw the right hand according to wound, wound is long 7 centimetres, dark 5 millimeters, through western medical treatment, suppurating sore suppurates after 7 days, it is excessive that palm of the hand skin is the peony pus that festers, the back of the hand swelling pain, limitation of activity.
Diagnosis: be " external injury cause skin and flesh fester suppuration ".
Treatment: through using Drug therapy of the present invention 10 days, pus goes out to the greatest extent, and swelling pain disappears, and skin color is light red, and 20 days skin ulcer face granulations, skin color recover normal.25 days skin ulcer faces calm down recovery from illness, give one of inventor's board.
Lin Mingjiang: man, 65 years old, the over one hundred village people in Xifeng County, Liaoning, examined private prosecution on August 5th, 2005: in bed by mosquito bite left foot face, find the place of biting water outlet, swollen, pain after 3 days, itch, pushed that through western medical treatment 7 days, the place's of biting nothing was clearly better with hands, it is heavier that instep portion is swollen with the pain gargalesthesia, can not walk.Through using 7 days congestion and swelling pains of Drug therapy of the present invention, be clearly better, malicious water is excessive more, and gargalesthesia is taken a favourable turn, and continues medication 10 days, and all diseases disappear.
Ma Desheng: man, 42 years old, Siping City people from Tiedong District, examined private prosecution on October 15th, 2006: diabetes 3 years, recent months is found the suppuration of festering of right sufficient face, 6 centimetres of sizes of the skin ulcer of festering face 7 cm x, dark 6 millimeters, swelling pain, surrounding skin is aubergine, slough is clearly visible, pus is excessive, and difficulty in walking does not have through western medical treatment and to be clearly better, hear that therapeutic effect is good herein, examined since the institute.
Three grades of diabetic foots that bring out for the viral infection type ii diabetes after diagnosing, used Drug therapy of the present invention 1 month, swelling, pain are obviously taken a favourable turn, and pus is excessive more, and the outer holder of slough obviously, continuing 2 months skin colors of medication replys normal, swelling pain disappears, and no pus, no slough exist, the granulation growth, the disappearance of all diseases was fully recovered in 3 months, and walking freely.
His private prosecution: orally-taken blood sugar reducing medicine not substantially, blood glucose is balance relatively.
5, discuss: external injury causes the fester diseases such as diabetic foot of suppuration, skin infection, viral infection diabetes-induced of skin and flesh, belongs to the category of motherland's medical science surgical diseases, be morbidity anxious, cure slow sufferer.
Though above disease is distinguished to some extent, because of pathogenesis identical, so method of treatment is identical.Only in clinical according to the patient hinder weight, concrete handle just passable.
What mainly discuss is through more than 20 year clinical experience of inventor, and to three grades of diabetic foots of due to illness poison infection, III type diabetes-induced, further discussion, research are found to some extent.
We can say that virus is eliminated from the open sore part and discharged, blood glucose is relatively also with regard to balance, and virus is grown and spread unchecked, natural blood sugar increasing, has a strong impact on insulin and normally secretes, and various symptoms occur, as numbness of hands and feet, urinary tract infection, myocarditis, diabetic foot etc.
More than three kinds of diseases, treatment should heat-clearing and toxic substances removing, heat clearing and damp drying, the evacuation of pus of drawing out pus by applying a plaster to the affected part, edema eliminating stagnation, putrefaction-removing granulation-promoting, pain relieving analgesic therapy, blood circulation promoting and blood stasis dispelling, blood circulation promoting, the reparation of quickening ulcer surface.
In the side: Colophonium, Radix Ampelopsis, Pseudobulbus Bletillae (Rhizoma Bletillae) heat-clearing and toxic substances removing, dampness, draw out pus by applying a plaster to the affected part, evacuation of pus, granulation promoting, pain relieving, analgesic therapy, liana skin ulcer.
Oleum Sesami, Cera Flava, detoxifcation, granulation promoting.
Pseudobulbus cremastrae seu pleiones, Herba Houttuyniae, heat-clearing and toxic substances removing, removing blood stasis and expelling pus, detumescence, analgesic therapy, eliminating stagnation.
Olibanum, Myrrha, blood circulation promoting and blood stasis dispelling, circulation of qi promoting, subduing swelling and relieving pain, pain relieving.
Radix Sophorae Flavescentis, Cortex Dictamni, heat clearing and damp drying, noxious dampness skin infection, skin pruritus, blood tinea corporis skin ulcer, rubella, eczema, mashed bad, the impetigo of strong wind brothers.
All medicines share, and Baconic consolidates, strengthening vital QI to eliminate pathogenic factors, and soothing liver-QI for relieving depression, the gentle wood of nourishing the liver, QI and blood regulating, the effect of nourishing the liver and kidney, treating both the principal and secondary aspects of a disease embodies the treatment skin and flesh disease of festering; The Therapeutic Principle who disappears, holds in the palm, mends, just middle pathogenesis, all disease spontaneous recovery.
[specific embodiment] is described in detail below with reference to embodiments of the invention
Medicine of the present invention at first with ten simply 20 part of seven flavor of 20 parts of 16 parts of 15 parts of 15 parts of 30 parts of 60 parts in Oleum Sesami, Radix Ampelopsis, the Pseudobulbus Bletillae (Rhizoma Bletillae)s, Pseudobulbus cremastrae seu pleiones, Herba Houttuyniae, Radix Sophorae Flavescentiss, the Cortex Dictamni in Chinese medicine Chinese medicine together put into pot and soak at normal temperatures, soak seven days, summer winter and soaked three.Then soaked seven flavor Chinese medicines are lit a fire and boil, wait to boil little withered medicinal liquid is removed slag and put into 50 parts of Colophonium immediately after filtering, Cera Flava is withdrawn burning things which may cause a fire disaster after treating for 45 parts fully to dissolve, when temperature is reduced to 40 ℃, put into 5 parts of Olibanums, 7 parts of Myrrhas fully stir cool completely into cream medicine of the present invention.

Claims (2)

1. the skin and flesh that causes of the external injury of the treatment external-applied ointment of disease that festers is characterized in that it is made by the raw material of following weight parts
2. a kind of fester preparation method of external-applied ointment of disease of skin and flesh that external injury causes for the treatment of according to claim 1, it is characterized in that its preparation method may further comprise the steps, at first with ten Oleum Sesami in the Chinese herbal medicine simply, Radix Ampelopsis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Pseudobulbus cremastrae seu pleiones, Herba Houttuyniae, Radix Sophorae Flavescentis, Cortex Dictamni seven flavor Chinese medicines are together put into pot in proportion and are soaked at normal temperatures, soaked winter seven, soaked summer three, then soaked seven flavor Chinese medicines are lit a fire and boil, wait to boil little withered with medicinal liquid remove slag filter after, put into Colophonium immediately by weight proportion, after Cera Flava is treated fully to dissolve, withdraw burning things which may cause a fire disaster, when temperature is reduced to 40 ℃, put into frankincense powder, do not have medicated powder fully to stir and cool completely into cream, last sterilization packaging gets final product.
CN2008101460651A 2008-08-07 2008-08-07 Externally applied ointment for treating surgery diseases and preparation method thereof Expired - Fee Related CN101642530B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101229322A (en) * 2007-11-26 2008-07-30 倪建忠 External medicine for treating surgery and dermatology department diseases and preparing method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101229322A (en) * 2007-11-26 2008-07-30 倪建忠 External medicine for treating surgery and dermatology department diseases and preparing method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
兰海梅.中医药治疗小腿溃疡概况.《时珍国医国药》.2006,第17卷(第3期),第420-421页. *
宋兆友.常用皮肤病中药外用制剂介绍.《皮肤病与性病》.2006,第28卷(第1期),第23-25页. *

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