CN101637578A

CN101637578A - Medicinal preparation for treating acnes, whelks and folliculitis and preparation method thereof

Info

Publication number: CN101637578A
Application number: CN200910100553A
Authority: CN
Inventors: 朱建华
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-07-07
Filing date: 2009-07-07
Publication date: 2010-02-03

Abstract

The invention discloses a medicinal preparation for treating acnes, whelks and folliculitis and a preparation method thereof. The medicinal preparation is mainly prepared from fructus forsythiae, honeysuckle, scutellaria baicalensis, radix sophorae flavescentis, spina gleditsiae, isatis roots, Paris polyphylla, loquat leaves, angelica sinensis, radix salviae miltiorrhizae, amur corktree barks, rhizoma coptidis, flos chrysanthemi indici, dark plum fruit, mint, sticky rice and cavings by adopting a conventional fermentation process of adding Chinese yeast, lump mold cultures and yeast. The medicinal preparation has the effects of oil control, antibiosis and inflammation diminishing, and proved by clinical experiments, the medicinal preparation has unique curative effect on the acnes, the whelks and the folliculitis. Generally, the medicinal preparation can get effective after being taken for three days and has no side effect after long-term use. The medicinal preparation has wide medicine source, simple preparation, remarkable curative effect and worthy popularization.

Description

A kind of pharmaceutical preparation for the treatment of acne, comedo, folliculitis and preparation method thereof

Technical field:

The present invention relates to a kind of pharmaceutical preparation for the treatment of acne, comedo, folliculitis, the invention still further relates to the preparation method of this medicine, belong to Chinese medicine ferment making field.

Background technology:

Acne vulgaris (abbreviation acne) is a kind of pilosebaceous chronic inflammatory disease dermatosis that betides.Another name has: acne, whelk, comedo, skin sore etc.Be common in positions such as face, shirtfront, back and blackhead, hoary hair's acne, pustule, cyst, areolar tissue etc. occur.The traditional Chinese medical science is called the lung-wind syndrome whelk, thinks relevant with " hot, strongly fragrant, wet, the stasis of blood ".Western medicine thinks that the mechanism of primary disease includes following four morbidity links.1: androgen and sebaceous gland hyperfunctioning.2: infundibulum of hair follicle portion hyperkeratosis.3: action of microorganisms in the pilosebaceous unit.4: inflammation and host's immunoreation.Wherein active is that sebum secretion increases, and the growth of sebaceous gland and secretion are subjected to androgenic domination, androgen also can make pilosebaceous unit epithelium generation keratinization and make the channel narrows of draining sebum, too much sebum row is not gone out, savings is in the pilosebaceous unit system, original normal flora imbalance in the sebaceous gland at this moment, the enzyme that decomposes sebum can be bred and produce to the skin ulcer propionibacterium of fullying recover from an illness wherein in a large number.After sebum decomposed, the free fatty of generation stimulated also damage surrounding tissue, causes the inflammatory reaction based on sebaceous gland and follicular orifice, and this has just formed sebum and has increased, and----arranging fat-----bacterial infection that is obstructed is the acne pathogenesis in axle center.Certainly, also also have many other risk factors: also in action as Personal hygiene, skin type, living habit and overall health of patients.

Though the external medicine preparation kind of treatment acne, folliculitis is more at present, has many drawbacks, as weak curative effect, the relapse rate height; It is many that medicine is formed with Western medicine, and shortcoming is that zest is strong, and side effect is bigger, and the improper use meeting increases the weight of the state of an illness.

Summary of the invention:

Purpose of the present invention is exactly at the prior art deficiency, and the pharmaceutical preparation of a kind of easy to use, determined curative effect, treatment acne that toxic and side effects is little, comedo, folliculitis is provided for society.

Another object of the present invention just provides the preparation method of the pharmaceutical preparation of this treatment acne, comedo, folliculitis.

It is at the theory of Chinese medicine about acne that the solution of the object of the invention adopts, and based on motherland's medical science pathogenetic understanding of acne and Therapeutic Principle is filtered out tens of kinds of medicines, realizes with the following method:

Raw material in the pharmaceutical preparation of the present invention comes from natural plants: Oryza glutinosa, bran coat, Fructus Forsythiae, Flos Lonicerae, Radix Scutellariae, Radix Sophorae Flavescentis, Spina Gleditsiae, Radix Isatidis, Rhizoma Paridis, Folium Eriobotryae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Rhizoma Coptidis, Flos Chrysanthemi Indici, Fructus Mume, Herba Menthae, have no side effect at no hormone.The medicament composing prescription principle is:

Fructus Forsythiae: heat clearing away, detoxifcation, eliminating stagnation, detumescence;

Flos Lonicerae: heat-clearing and toxic substances removing, dispelling wind collateral dredging;

Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication is doublely gone into blood system, can removing heat from blood and stop blooding;

Radix Sophorae Flavescentis: heat clearing and damp drying, killing parasites for relieving itching;

Spina Gleditsiae: detumescence poison holding, evacuation of pus, parasite killing;

Radix Isatidis: heat clearing away, detoxifcation, removing heat from blood;

Rhizoma Paridis: heat-clearing and toxic substances removing, reducing swelling and alleviating pain;

Folium Eriobotryae: clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI;

Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, loosening bowel to relieve constipation;

Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle;

Cortex Phellodendri: heat clearing and damp drying, eliminating fire and detoxication;

Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication;

Flos Chrysanthemi Indici: heat-clearing and toxic substances removing;

Fructus Mume: astringe the lung, promote the production of body fluid;

Herba Menthae: saturating dermexanthesis poison.

All medicines cooperate, and respectively execute the chief, and synergism is evident in efficacy.By pharmaceutical properties, pharmacological action after the fermenting process of preparing a series of variations take place, the effect of its control oils and fats anti-inflammation is better.

Each raw material consumption is respectively (by weight) among the present invention:

1000 parts of system liquor raw materials (Oryza glutinosa, bran coat, yeast for brewing rice wine, piece song, yeast etc.), 10 parts of Fructus Forsythiaes, 10 parts of Flos Lonicerae, 10 parts of Radix Scutellariaes, 10 parts of Radix Sophorae Flavescentiss, 10 parts of Spina Gleditsiaes, 10 parts of Radix Isatidis, 10 parts of Rhizoma Paridis, 10 parts of Folium Eriobotryaes, 30 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts of Cortex Phellodendris, 10 parts of Rhizoma Coptidis, 10 parts of Flos Chrysanthemi Indicis, 10 parts of Fructus Mumes, 10 parts of Herba Menthaes

The preparation method of pharmaceutical preparation of the present invention is as follows:

1: 10 parts the chopping back is standby respectively for 10 parts of Fructus Forsythiaes, 10 parts of Flos Lonicerae, 10 parts of Radix Scutellariaes, 10 parts of Radix Sophorae Flavescentiss, 10 parts of Spina Gleditsiaes, 10 parts of Radix Isatidis, 10 parts of Rhizoma Paridis, 10 parts of Folium Eriobotryaes, 30 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts of Cortex Phellodendris, 10 parts of Rhizoma Coptidis, 10 parts of Flos Chrysanthemi Indicis, 10 parts of Fructus Mumes, Herba Menthae.

2: get to pulverize and join after 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of 15 parts of 15 parts of 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of Fructus Forsythiaes, Flos Lonicerae, Radix Scutellariaes, Radix Sophorae Flavescentiss, Spina Gleditsiaes, Radix Isatidis, Rhizoma Paridis, Folium Eriobotryaes, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizaes, Cortex Phellodendris, Rhizoma Coptidis, Flos Chrysanthemi Indicis, Fructus Mumes, Herba Menthaes later cook in 1000 parts of system liquor raw materials, pour big wine jar after stirring into, smooth out with the fingers flat, dig a little pool in central authorities, putting the bamboo beach wormwood seals wine vat then, the temperature for the treatment of fermentation materials reaches 24-28 ℃, keeps 5 days.

After 3:5 days, the long-pending full fermented glutinous rice of bamboo beach wormwood in the intermediary little pool of wine vat, get and pulverize 5 parts of Fructus Forsythiaes later, 5 parts of Flos Lonicerae, 5 parts of Radix Scutellariaes, 5 parts of Radix Sophorae Flavescentiss, 5 parts of Spina Gleditsiaes, 5 parts of Radix Isatidis, 5 parts of Rhizoma Paridis, 5 parts of Folium Eriobotryaes, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Salviae Miltiorrhizaes, 5 parts of Cortex Phellodendris, 5 parts of Rhizoma Coptidis, 5 parts of Flos Chrysanthemi Indicis, 5 parts of Fructus Mumes, 5 parts of Herba Menthaes cook the back and add by step 2 and obtain fermenting in the material of back, and cold water poured in the cylinder for 2000 parts, flood material, after mixing evenly, the cylinder cap of filling a wine cup for again sternly continues fermentation, the temperature of fermentation materials can rise to 38-39 ℃, about the 5th day, temperature is reduced to 33-35 ℃, shows that alcohol fermentation finishes.

4: material after the fermentation that will obtain by step 3, take out and put into steaming kier and distill, the steam that comes out from steaming kier is through cooling, and the gained filling liquid is promptly.

Through clinical verification, show that this medical instrument has: suppress the effect of sebaceous gland hyperfunctioning, anti-sebum dyskeratosis, inhibition growth of microorganism, inflammation-inhibiting.Acne, comedo, folliculitis are had unique curative effect, and general 3 days take effect, and life-time service is free from side effects, and the medicine source is extensive, and preparation is simple, and determined curative effect is worthy to be popularized.

Specific embodiment 1:

(1) it is standby that Fructus Forsythiae 10kg, Flos Lonicerae 10kg, Radix Scutellariae 10kg, Radix Sophorae Flavescentis 10kg, Spina Gleditsiae 10kg, Radix Isatidis 10kg, Rhizoma Paridis 10kg, Folium Eriobotryae 10kg, Radix Angelicae Sinensis 30kg, Radix Salviae Miltiorrhizae 30kg, Cortex Phellodendri 10kg, Rhizoma Coptidis 10kg, Flos Chrysanthemi Indici 10kg, Fructus Mume 10kg, Herba Menthae 10kg shred the back respectively.

(2) get to pulverize and join after Fructus Forsythiae 5kg, Flos Lonicerae 5kg, Radix Scutellariae 5kg, Radix Sophorae Flavescentis 5kg, Spina Gleditsiae 5kg, Radix Isatidis 5kg, Rhizoma Paridis 5kg, Folium Eriobotryae 5kg, Radix Angelicae Sinensis 15kg, Radix Salviae Miltiorrhizae 15kg, Cortex Phellodendri 5kg, Rhizoma Coptidis 5kg, Flos Chrysanthemi Indici 5kg, Fructus Mume 5kg, Herba Menthae 5kg later cooks in the 1000kg system liquor raw material, pour big wine jar after stirring into, smooth out with the fingers flat, dig a little pool in central authorities, putting the bamboo beach wormwood seals wine vat then, the temperature for the treatment of fermentation materials reaches 24-28 ℃, keeps 5 days.

After (3) 5 days, the long-pending full fermented glutinous rice of bamboo beach wormwood in the intermediary little pool of wine vat, get and pulverize Fructus Forsythiae 5kg later, Flos Lonicerae 5kg, Radix Scutellariae 5kg, Radix Sophorae Flavescentis 5kg, Spina Gleditsiae 5kg, Radix Isatidis 5kg, Rhizoma Paridis 5kg, Folium Eriobotryae 5kg, Radix Angelicae Sinensis 15kg, Radix Salviae Miltiorrhizae 15kg, Cortex Phellodendri 5kg, Rhizoma Coptidis 5kg, Flos Chrysanthemi Indici 5kg, Fructus Mume 5kg, Herba Menthae 5kg cooks the back and adds by step 2 and obtain fermenting in the material of back, and cold water 2000kg poured in the cylinder, flood material, after mixing evenly, the cylinder cap of filling a wine cup for again sternly continues fermentation, the temperature of fermentation materials can rise to 38-39 ℃, about the 5th day, temperature is reduced to 33-35 ℃, shows that alcohol fermentation finishes.

(4) material after the fermentation that will be obtained by step (3) takes out and puts into steaming kier and distill, and the steam that comes out from steaming kier is through cooling, and the gained filling liquid promptly.

Claims

1 one kinds of pharmaceutical preparatioies for the treatment of acne, comedo, folliculitis.It is characterized in that containing following composition and consumption thereof (by weight):

1000 parts of system liquor raw materials (Oryza glutinosa, bran coat, yeast for brewing rice wine, piece song, yeast etc.), 10 parts of Fructus Forsythiaes, 10 parts of Flos Lonicerae, 10 parts of Radix Scutellariaes, 10 parts of Radix Sophorae Flavescentiss, 10 parts of Fructus Gleditsia, 10 parts of Radix Isatidis, 10 parts of Rhizoma Paridis, 10 parts of Folium Eriobotryaes, 30 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts of Cortex Phellodendris, 10 parts of Rhizoma Coptidis, 10 parts of Flos Chrysanthemi Indicis, 10 parts of Fructus Mumes, 10 parts of Herba Menthaes.

2, a kind of preparation method for the treatment of the pharmaceutical preparation of acne, comedo, folliculitis.It is characterized in that:

A: 10 parts the chopping back is standby respectively for 10 parts of Fructus Forsythiaes, 10 parts of Flos Lonicerae, 10 parts of Radix Scutellariaes, 10 parts of Radix Sophorae Flavescentiss, 10 parts of Fructus Gleditsia, 10 parts of Radix Isatidis, 10 parts of Rhizoma Paridis, 10 parts of Folium Eriobotryaes, 30 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts of Cortex Phellodendris, 10 parts of Rhizoma Coptidis, 10 parts of Flos Chrysanthemi Indicis, 10 parts of Fructus Mumes, Herba Menthae.

B: get to pulverize and join after 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of 15 parts of 15 parts of 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of 5 parts of Fructus Forsythiaes, Flos Lonicerae, Radix Scutellariaes, Radix Sophorae Flavescentiss, Fructus Gleditsia, Radix Isatidis, Rhizoma Paridis, Folium Eriobotryaes, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizaes, Cortex Phellodendris, Rhizoma Coptidis, Flos Chrysanthemi Indicis, Fructus Mumes, Herba Menthaes later cook in 1000 parts of system liquor raw materials, pour big wine jar after stirring into, smooth out with the fingers flat, dig a little pool in central authorities, putting the bamboo beach wormwood seals wine vat then, the temperature for the treatment of fermentation materials reaches 24-28 ℃, keeps 5 days.

After C:5 days, the long-pending full fermented glutinous rice of bamboo beach wormwood in the intermediary little pool of wine vat, get and pulverize 5 parts of Fructus Forsythiaes later, 5 parts of Flos Lonicerae, 5 parts of Radix Scutellariaes, 5 parts of Radix Sophorae Flavescentiss, 5 parts of Fructus Gleditsia, 5 parts of Radix Isatidis, 5 parts of Rhizoma Paridis, 5 parts of Folium Eriobotryaes, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Salviae Miltiorrhizaes, 5 parts of Cortex Phellodendris, 5 parts of Rhizoma Coptidis, 5 parts of Flos Chrysanthemi Indicis, 5 parts of Fructus Mumes, 5 parts of Herba Menthaes cook the back and add by step B and obtain fermenting in the material of back, and cold water poured in the cylinder for 2000 parts, flood material, after mixing evenly, the cylinder cap of filling a wine cup for again sternly continues fermentation, the temperature of fermentation materials can rise to 38-39 ℃, about the 5th day, temperature is reduced to 33-35 ℃, shows that alcohol fermentation finishes.

D: material after the fermentation that will obtain by step C, take out and put into steaming kier and distill, the steam that comes out from steaming kier is through cooling, and the gained filling liquid is promptly.