CN101637172B - Insecticidal/acaricidal composition having lufenuron and tebufenozide - Google Patents
Insecticidal/acaricidal composition having lufenuron and tebufenozide Download PDFInfo
- Publication number
- CN101637172B CN101637172B CN 200910146853 CN200910146853A CN101637172B CN 101637172 B CN101637172 B CN 101637172B CN 200910146853 CN200910146853 CN 200910146853 CN 200910146853 A CN200910146853 A CN 200910146853A CN 101637172 B CN101637172 B CN 101637172B
- Authority
- CN
- China
- Prior art keywords
- lufenuron
- insecticidal
- composition
- worm hydrazides
- acaricidal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000005912 Lufenuron Substances 0.000 title claims abstract description 95
- PWPJGUXAGUPAHP-UHFFFAOYSA-N lufenuron Chemical compound C1=C(Cl)C(OC(F)(F)C(C(F)(F)F)F)=CC(Cl)=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F PWPJGUXAGUPAHP-UHFFFAOYSA-N 0.000 title claims abstract description 95
- 229960000521 lufenuron Drugs 0.000 title claims abstract description 95
- 239000000203 mixture Substances 0.000 title claims abstract description 39
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 16
- 230000000895 acaricidal effect Effects 0.000 title claims abstract description 14
- 239000005937 Tebufenozide Substances 0.000 title abstract description 8
- QYPNKSZPJQQLRK-UHFFFAOYSA-N tebufenozide Chemical compound C1=CC(CC)=CC=C1C(=O)NN(C(C)(C)C)C(=O)C1=CC(C)=CC(C)=C1 QYPNKSZPJQQLRK-UHFFFAOYSA-N 0.000 title abstract description 8
- 241000500437 Plutella xylostella Species 0.000 claims abstract description 22
- 239000004530 micro-emulsion Substances 0.000 claims abstract description 16
- 239000000375 suspending agent Substances 0.000 claims abstract description 11
- 241000985245 Spodoptera litura Species 0.000 claims abstract description 6
- 241001414989 Thysanoptera Species 0.000 claims abstract description 6
- 241000018137 Trialeurodes vaporariorum Species 0.000 claims abstract description 5
- 239000000839 emulsion Substances 0.000 claims abstract description 5
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims abstract description 5
- 238000009736 wetting Methods 0.000 claims abstract description 5
- 239000000843 powder Substances 0.000 claims abstract description 4
- 241000255777 Lepidoptera Species 0.000 claims abstract description 3
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 3
- 241000238876 Acari Species 0.000 claims abstract 2
- 241000258937 Hemiptera Species 0.000 claims abstract 2
- 229940042795 hydrazides for tuberculosis treatment Drugs 0.000 claims description 79
- 241000238631 Hexapoda Species 0.000 claims description 14
- 241000256247 Spodoptera exigua Species 0.000 claims description 11
- 241000255969 Pieris brassicae Species 0.000 claims description 6
- 241000255967 Helicoverpa zea Species 0.000 claims description 5
- 241001486250 Etiella zinckenella Species 0.000 claims description 3
- 240000001307 Myosotis scorpioides Species 0.000 claims description 3
- 241000426497 Chilo suppressalis Species 0.000 claims description 2
- 241001046947 Ectropis obliqua Species 0.000 claims description 2
- 241000510199 Helicoverpa assulta Species 0.000 claims description 2
- 244000269722 Thea sinensis Species 0.000 claims description 2
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 43
- 241000607479 Yersinia pestis Species 0.000 abstract description 14
- 239000000575 pesticide Substances 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 8
- 229940079593 drug Drugs 0.000 abstract description 7
- 239000004615 ingredient Substances 0.000 abstract description 3
- 239000000546 pharmaceutical excipient Substances 0.000 abstract description 3
- 238000001228 spectrum Methods 0.000 abstract description 2
- 241000934067 Acarus Species 0.000 abstract 1
- 239000000447 pesticide residue Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 24
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 24
- 238000010790 dilution Methods 0.000 description 19
- 239000012895 dilution Substances 0.000 description 19
- -1 alkyl phenol formaldehyde resin Chemical compound 0.000 description 16
- 238000012360 testing method Methods 0.000 description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
- 230000002195 synergetic effect Effects 0.000 description 10
- 235000013311 vegetables Nutrition 0.000 description 10
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 239000003795 chemical substances by application Substances 0.000 description 9
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 8
- 239000008367 deionised water Substances 0.000 description 8
- 229910021641 deionized water Inorganic materials 0.000 description 8
- 238000002360 preparation method Methods 0.000 description 8
- 239000007921 spray Substances 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 239000002202 Polyethylene glycol Substances 0.000 description 6
- 235000011187 glycerol Nutrition 0.000 description 6
- 239000002917 insecticide Substances 0.000 description 6
- PHTQWCKDNZKARW-UHFFFAOYSA-N isoamylol Chemical compound CC(C)CCO PHTQWCKDNZKARW-UHFFFAOYSA-N 0.000 description 6
- 230000002045 lasting effect Effects 0.000 description 6
- 229920001223 polyethylene glycol Polymers 0.000 description 6
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 6
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- 235000014113 dietary fatty acids Nutrition 0.000 description 5
- 238000009313 farming Methods 0.000 description 5
- 239000000194 fatty acid Substances 0.000 description 5
- 229930195729 fatty acid Natural products 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000005711 Benzoic acid Substances 0.000 description 4
- 239000004372 Polyvinyl alcohol Substances 0.000 description 4
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 239000012752 auxiliary agent Substances 0.000 description 4
- 235000010233 benzoic acid Nutrition 0.000 description 4
- 239000004359 castor oil Substances 0.000 description 4
- 235000019438 castor oil Nutrition 0.000 description 4
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 4
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 4
- 150000002170 ethers Chemical class 0.000 description 4
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 4
- 235000010234 sodium benzoate Nutrition 0.000 description 4
- 239000004299 sodium benzoate Substances 0.000 description 4
- 239000003381 stabilizer Substances 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- HVLLSGMXQDNUAL-UHFFFAOYSA-N triphenyl phosphite Chemical compound C=1C=CC=CC=1OP(OC=1C=CC=CC=1)OC1=CC=CC=C1 HVLLSGMXQDNUAL-UHFFFAOYSA-N 0.000 description 4
- LRWZZZWJMFNZIK-UHFFFAOYSA-N 2-chloro-3-methyloxirane Chemical compound CC1OC1Cl LRWZZZWJMFNZIK-UHFFFAOYSA-N 0.000 description 3
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 244000068988 Glycine max Species 0.000 description 3
- 235000010469 Glycine max Nutrition 0.000 description 3
- 244000299507 Gossypium hirsutum Species 0.000 description 3
- 241000124008 Mammalia Species 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 239000004283 Sodium sorbate Substances 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 239000003995 emulsifying agent Substances 0.000 description 3
- 239000003630 growth substance Substances 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 238000011835 investigation Methods 0.000 description 3
- 231100000053 low toxicity Toxicity 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 235000019198 oils Nutrition 0.000 description 3
- 229940051841 polyoxyethylene ether Drugs 0.000 description 3
- 229920000056 polyoxyethylene ether Polymers 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- LROWVYNUWKVTCU-STWYSWDKSA-M sodium sorbate Chemical compound [Na+].C\C=C\C=C\C([O-])=O LROWVYNUWKVTCU-STWYSWDKSA-M 0.000 description 3
- 235000019250 sodium sorbate Nutrition 0.000 description 3
- 229910052938 sodium sulfate Inorganic materials 0.000 description 3
- 235000011152 sodium sulphate Nutrition 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 2
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 2
- BWDBEAQIHAEVLV-UHFFFAOYSA-N 6-methylheptan-1-ol Chemical compound CC(C)CCCCCO BWDBEAQIHAEVLV-UHFFFAOYSA-N 0.000 description 2
- 244000215068 Acacia senegal Species 0.000 description 2
- 241001124076 Aphididae Species 0.000 description 2
- 241000256844 Apis mellifera Species 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 2
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 2
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 2
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- 229920000084 Gum arabic Polymers 0.000 description 2
- 239000005639 Lauric acid Substances 0.000 description 2
- 229920001732 Lignosulfonate Polymers 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 2
- 240000007594 Oryza sativa Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 244000061456 Solanum tuberosum Species 0.000 description 2
- 235000002595 Solanum tuberosum Nutrition 0.000 description 2
- 235000021355 Stearic acid Nutrition 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 235000009754 Vitis X bourquina Nutrition 0.000 description 2
- 235000012333 Vitis X labruscana Nutrition 0.000 description 2
- 240000006365 Vitis vinifera Species 0.000 description 2
- 235000014787 Vitis vinifera Nutrition 0.000 description 2
- 240000008042 Zea mays Species 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 235000010489 acacia gum Nutrition 0.000 description 2
- 239000000205 acacia gum Substances 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- 239000013530 defoamer Substances 0.000 description 2
- 239000002270 dispersing agent Substances 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 230000010534 mechanism of action Effects 0.000 description 2
- 229920000609 methyl cellulose Polymers 0.000 description 2
- 239000001923 methylcellulose Substances 0.000 description 2
- 235000010981 methylcellulose Nutrition 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- IXQGCWUGDFDQMF-UHFFFAOYSA-N o-Hydroxyethylbenzene Natural products CCC1=CC=CC=C1O IXQGCWUGDFDQMF-UHFFFAOYSA-N 0.000 description 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 230000003151 ovacidal effect Effects 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 229920001451 polypropylene glycol Polymers 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 230000003449 preventive effect Effects 0.000 description 2
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 2
- 239000002728 pyrethroid Substances 0.000 description 2
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 239000010668 rosemary oil Substances 0.000 description 2
- 229940058206 rosemary oil Drugs 0.000 description 2
- 229960004889 salicylic acid Drugs 0.000 description 2
- 235000010413 sodium alginate Nutrition 0.000 description 2
- 239000000661 sodium alginate Substances 0.000 description 2
- 229940005550 sodium alginate Drugs 0.000 description 2
- 235000010199 sorbic acid Nutrition 0.000 description 2
- 239000004334 sorbic acid Substances 0.000 description 2
- 229940075582 sorbic acid Drugs 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000008117 stearic acid Substances 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 125000003944 tolyl group Chemical group 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 1
- QWUWMCYKGHVNAV-UHFFFAOYSA-N 1,2-dihydrostilbene Chemical group C=1C=CC=CC=1CCC1=CC=CC=C1 QWUWMCYKGHVNAV-UHFFFAOYSA-N 0.000 description 1
- 150000005208 1,4-dihydroxybenzenes Chemical class 0.000 description 1
- 150000004782 1-naphthols Chemical class 0.000 description 1
- YSUQLAYJZDEMOT-UHFFFAOYSA-N 2-(butoxymethyl)oxirane Chemical compound CCCCOCC1CO1 YSUQLAYJZDEMOT-UHFFFAOYSA-N 0.000 description 1
- CUFXMPWHOWYNSO-UHFFFAOYSA-N 2-[(4-methylphenoxy)methyl]oxirane Chemical compound C1=CC(C)=CC=C1OCC1OC1 CUFXMPWHOWYNSO-UHFFFAOYSA-N 0.000 description 1
- AOBIOSPNXBMOAT-UHFFFAOYSA-N 2-[2-(oxiran-2-ylmethoxy)ethoxymethyl]oxirane Chemical compound C1OC1COCCOCC1CO1 AOBIOSPNXBMOAT-UHFFFAOYSA-N 0.000 description 1
- 241000238421 Arthropoda Species 0.000 description 1
- 241000193388 Bacillus thuringiensis Species 0.000 description 1
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 235000006008 Brassica napus var napus Nutrition 0.000 description 1
- 240000007124 Brassica oleracea Species 0.000 description 1
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 1
- 244000178937 Brassica oleracea var. capitata Species 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 241001674939 Caulanthus Species 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 241000675108 Citrus tangerina Species 0.000 description 1
- 241001498622 Cixius wagneri Species 0.000 description 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 1
- 229920005682 EO-PO block copolymer Polymers 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 description 1
- 240000001624 Espostoa lanata Species 0.000 description 1
- 235000009161 Espostoa lanata Nutrition 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- HSRJKNPTNIJEKV-UHFFFAOYSA-N Guaifenesin Chemical compound COC1=CC=CC=C1OCC(O)CO HSRJKNPTNIJEKV-UHFFFAOYSA-N 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- 241001325860 Lacanobia oleracea Species 0.000 description 1
- 150000007945 N-acyl ureas Chemical class 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- FQYUMYWMJTYZTK-UHFFFAOYSA-N Phenyl glycidyl ether Chemical compound C1OC1COC1=CC=CC=C1 FQYUMYWMJTYZTK-UHFFFAOYSA-N 0.000 description 1
- 241001525654 Phyllocnistis citrella Species 0.000 description 1
- 244000082204 Phyllostachys viridis Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 241000176086 Sogatella furcifera Species 0.000 description 1
- 208000031320 Teratogenesis Diseases 0.000 description 1
- 241001454293 Tetranychus urticae Species 0.000 description 1
- 241000256856 Vespidae Species 0.000 description 1
- ABUGVBRDFWGJRD-CHOYNLESSA-N [9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-methyloxolan-2-yl]-2-(2,4-dinitrophenyl)sulfanylpurin-6-yl] [hydroxy(phosphonooxy)phosphoryl] hydrogen phosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](C)O[C@H]1N1C2=NC(SC=3C(=CC(=CC=3)[N+]([O-])=O)[N+]([O-])=O)=NC(OP(O)(=O)OP(O)(=O)OP(O)(O)=O)=C2N=C1 ABUGVBRDFWGJRD-CHOYNLESSA-N 0.000 description 1
- OASZCUUPKKGVSG-UHFFFAOYSA-N [O].NC(O)=N Chemical compound [O].NC(O)=N OASZCUUPKKGVSG-UHFFFAOYSA-N 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 150000008052 alkyl sulfonates Chemical class 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 229940097012 bacillus thuringiensis Drugs 0.000 description 1
- 238000000498 ball milling Methods 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 229960004365 benzoic acid Drugs 0.000 description 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 231100000315 carcinogenic Toxicity 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 239000000679 carrageenan Substances 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 229940113118 carrageenan Drugs 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 239000002734 clay mineral Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 239000007859 condensation product Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000002283 diesel fuel Substances 0.000 description 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 239000010440 gypsum Substances 0.000 description 1
- 229910052602 gypsum Inorganic materials 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000001418 larval effect Effects 0.000 description 1
- 239000008141 laxative Substances 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 231100000225 lethality Toxicity 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical group O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 229960002900 methylcellulose Drugs 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000005405 multipole Effects 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- RLLPVAHGXHCWKJ-UHFFFAOYSA-N permethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-UHFFFAOYSA-N 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 229940079877 pyrogallol Drugs 0.000 description 1
- 150000004040 pyrrolidinones Chemical class 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to an insecticidal (acaricidal) composition having lufenuron and tebufenozide and application thereof. The insecticidal (acaricidal) composition mainly comprises the lufenuron and the tebufenozide and comprises an accessory ingredient and excipients, wherein the mass part ratio of the lufenuron to the tebufenozide is 10:1-1:50. The composition can be prepared into microemulsion, a suspending agent, aqueous emulsion, water dispersible granules, wetting powder or missible oil. The insecticidal (acaricidal) composition has a synergy effect, broadens pest prevention spectra, overcomes and stays the drug fastness of the pest, prolongs the service life of pesticides, and reduces the cost and the pesticide residue. The composition can prevent and treat Lepidoptera, Homoptera, Thysanoptera, Acarina pest (acarus) on crops, especially can prevent and treat diamond back moth, spodoptera litura, trialeurodes vaporariorum, rust mite and the like. The effect of the composition is obviously better than that of two pesticides used separately.
Description
Technical field
The present invention relates to a kind of agriculture chemical compounding composition, be specifically related to a kind of insecticidal/acaricidal composition take lufenuron and worm hydrazides as main active.
Background technology
Lufenuron (Lufenuron), another name: chlorine is fragrant new, Lufenuron, fluorine the third oxygen urea, chemical name: N-[[[2,5-two chloro-4-(1,1,2,3,3,3-hexafluoro the third oxygen) phenyl] amino] carboxyl]-2, the 6-difluorobenzamide.Trade name: U.S.A removes.
Lufenuron belongs to the benzoyl area kind Insecticidal and acaricidal agent, is a kind of insect growth regulator, IGR, and its mechanism of action is suppress insect chitin synthetic, affects the formation of insect cuticle and reaches the insecticidal action purpose, has stomach toxicity and action of contace poison.
Lufenuron is mainly used in the crops such as corn, grape, soybean and vegetables.Lufenuron can be used to prevent and treat diamond-back moth, prodenia litura, cabbage caterpillar, beet armyworm, tomato moth, cotton bollworm, thrips, lima bean pod borer, rust mite, plant hopper, citrus leaf-miner etc., this product has outstanding preventive effect to food leaf caterpillars such as fruit trees, thrips, rust mite, trialeurodes vaporariorum there are unique mechanism of killing, are applicable to control pyrethroid and organophosphorous pesticide are produced resistant insect.The lasting period of lufenuron is long, is conducive to reduce the laxative number of times; To crop safety, corn, vegetables, oranges and tangerines, cotton, potato, grape, Soybean and Other Crops all can be used, and are suitable for Integrated pest and administer and Agricultural product without pollution.Lufenuron can not cause that sucking pest is rampant again, to the adult of beneficial insect and pounce on feeding habits mite action temperature and.The lasting medicine of lufenuron, resistance of rainwater washing against has selectivity to useful arthropods adult.Lufenuron has preferably ovicidal effect, can kill new product worm's ovum, 2～3 days visual effects after the dispenser.Lufenuron, can use during honeybee producting honey the mammal low toxicity honeybee and hornet low toxicity, and is relatively more safer than organic phosphor, carbamate chemicals for agriculture, can be used as good mixed agent and uses, and lepidoptera pest is had good control efficiency.
Worm hydrazides (Tebufenozide), chemical name: N-tertiary butyl-N '-(4-ethylamino benzonitrile acyl group)-3,5-dimethyl benzene hydrazides.Trade name: rice is full.
The worm hydrazides is the on-steroidal Novel insect growth regulator of U.S. rom Haars Co., Ltd nineteen ninety research and development, and its mechanism of action is to cast off a skin in the time should not casting off a skin behind the larval feeding, not exclusively causes larva dehydration, hungry and dead owing to casting off a skin.
The worm hydrazides is mainly used in preventing and treating the crops such as citrus, cotton, ornamental crops, potato, soybean, tobacco, fruit tree and vegetables.Tebufenozide pesticide is active high, and selectivity is strong, and speed of action is fast, and is all effective to all lepidopterous larvaes, and antagonism insect diamond-back moth, cotton bollworm, cabbage caterpillar, beet armyworm etc. have special efficacy, and extremely strong ovicidal activity is arranged, and be safer to non-target organism.The worm hydrazides is to eyes and skin nonirritant, and is without teratogenesis, carcinogenic, mutagenesis, all fool proof to mammal, birds, natural enemy to higher mammal.
The lufenuron shortcoming is that desinsection speed is slower, and the insecticide of needs and desinsection speed uses simultaneously.In addition, the lufenuron cost is higher, can not be applied to widely the crop pests control.
The long-term continuous single use of lufenuron or worm hydrazides easily causes pest resistance to insecticide, causes the pesticide resistance of insect more and more stronger, even causes pest resurgence, causes dosage to increase, and has so both increased cost accounting, has polluted again environment, has reduced crop quality.In recent years, some primary pests such as diamond-back moth, prodenia litura, beet armyworm, cabbage caterpillar, vegetable aphid, Trialeurodes vaporariorum Westwood etc. on China vegetables, rice field primary pest rice fulgorid and cotton primary pest aphid, two spotted spider mite, cotton bollworm etc., some conventional pesticide kinds have generally been produced resistance, caused that control efficiency obviously descends, pest resurgence.According to incompletely statistics, diamond-back moth produces resistance to more than the 50 kind of insecticide such as organochlorine, organic phosphor, carbamate, acylureas, bacillus thuringiensis,Bt, comprises growth regulator has also been produced resistance as pressing down hooligan, UC 62644 etc.; Prodenia litura all develops immunity to drugs to insecticides such as organochlorine, organic phosphor, carbamates, pyrethroid and Bt preparations.Therefore, development is efficient, low toxicity, low-residual complex preparation, helps to prevent and overcome pest to develop immunity to drugs, and helps to prolong the service life of pesticide species.
Summary of the invention
The object of the present invention is to provide a kind of synergistic composition that contains lufenuron and worm hydrazides.
The present invention a kind ofly is characterized in that take lufenuron and worm hydrazides as desinsection (mite) composition and the application thereof of main active effective ingredient is comprised of lufenuron and worm hydrazides, and its ratio of quality and the number of copies is 10: 1～1: 50, is preferably 1: 1～1: 20.Described active ingredient is present in the composition with the synergy effective dose, and the better mass fraction of effective ingredient lufenuron is 1%～10%, the better mass fraction of worm acyl calf is 1%～50%, and all the other are insecticides adjuvant and excipients (or filler).
The present invention can be used for preventing and treating the insects (mite) such as diamond-back moth, beet armyworm, striped rice borer, cabbage caterpillar, prodenia litura, lima bean pod borer, cotton bollworm, oriental tobacco budworm, tea geometrid, tea caterpillar, trialeurodes vaporariorum, thrips, rust mite take lufenuron and worm hydrazides as desinsection (mite) synergistic composition of primary activity composition.
The present invention is take active ingredient lufenuron and worm hydrazides as main, is mixed with microemulsion, suspending agent, aqueous emulsion, water dispersible granules, wetting powder or missible oil with suitable insecticides adjuvant, excipients (or filler).Described auxiliary agent determines that according to formulation the present invention conducts in-depth research the auxiliary agent of microemulsion and suspending agent, and scheme is respectively:
(1) when the preparation microemulsion, its auxiliary agent is: by quality of the pharmaceutical preparations emulsifier 5%～12%, solvent 3%～30%, stabilizing agent 0.1%～10%, antifreezing agent 0.1%～2%.Described emulsifier is NaLS, calcium dodecyl benzene sulfonate (agricultural newborn 500#), neopelex, lignosulfonates, carboxymethyl cellulose, Nongru-700 # (alkyl phenol formaldehyde resin polyoxyethylene ether), the newborn 400# of farming, the newborn 2201# of farming, TX-10 (Nonyl pheno (10) ether), triphen ethyl-phenol polyoxyethylene polyoxypropylene block polymer, phenethyl phenol polyethenoxy ethers (such as newborn 600# series of farming etc.), dibenzyl xenol polyethenoxy ether class (such as the newborn 300# of farming), castor oil polyoxyethylene ether is (such as the By emulsifier, peaceful breast 130 etc.), the EO-PO block copolymer, sorbitan fatty acid ester APEO (such as tween series), sorbitan fatty acid ester (such as Span series), Polypropylene Glycol Glycerin Ether, the mixture of one or more in the glycerin polyoxyethylene ether polyoxypropylene ether fatty acid ester; Described solvent is one or more the mixture in dimethylbenzene, toluene, methyl alcohol, ethanol, n-butanol, ethylene glycol, acetone, cyclohexanone, pyrrolidones, diesel oil, solvent naphtha (S-150, S-180, S-200), dimethyl formamide, dimethyl sulfoxide (DMSO), cyclohexane, the ethyl acetate, use when multiple, total usage amount can not be greater than the maximum of deal; Described stabilizing agent is one or more the mixture in methyl alcohol, benzinum, urea, wettable starch, triphenyl phosphite, epoxychloropropane, aceticanhydride, the tolyl glycidic alcohol; Described antifreezing agent is one or more the mixture in glycerine, propane diols, ethylene glycol, sodium chloride, sorbierite, the sorbic acid.
(2) when the preparation suspending agent, its auxiliary agent is: by quality of the pharmaceutical preparations wetting dispersing agent 1%～40%, thickener 0.1%～10%, defoamer 0.5%～10%, stabilizing agent 0%～10%, preservative 0%～5%, antifreezing agent 0.1%～5%.Described wetting dispersing agent is that alkylphenol polyoxyethylene formaldehyde condensation products sodium sulphate is (such as SOPA230,235 etc.), lauryl alcohol polyethylene glycol oxide base ether sodium sulfate, alkylnaphthalene sulfonate (pulling open powder etc.), dialkyl succinylsuccinate sulfonate, alkylphosphonic, alkylnaphthalene sulfonate, alkylsulfonate, the alkylaryl naphthalene sulfonate, aliphatic alcohol sulfate, lignin and derivative sulfonate thereof, sorbitan fatty acid ester polyoxyethylene ether--tween series, the glycerin polyoxyethylene polyethenoxy ether, alkylphenol polyoxyethylene, fatty alcohol polyethenoxy ether class (such as JFC), phenethyl phenol polyethenoxy ethers, the polyoxyethylene poly-oxygen propylene aether block copolymer, the alkylpolyoxyethylene phosphate, starch, gelatin, polyvinyl alcohol etc. can be one or more mixtures; Described thickener is xanthans, pectin, gelatin, gum Arabic, guar gum, polyvinyl alcohol, the basic cellulose of hydroxyl first (second), methylcellulose, sodium alginate, carrageenan, clay mineral (such as bentonite), Magnesiumaluminumsilicate, soluble starch, dispersed silica gel, gaseous state silica, gypsum etc. can be one or more mixtures; Described defoamer is higher alcohol (such as isooctanol, isoamyl alcohol etc.), fatty acid (lauric acid, stearic acid etc.), silicone etc., can be one or more mixture; Described stabilizing agent is xanthan gum, pyrogallol, salicylic acid, ascorbic acid, sodium sorbate, Sodium Benzoate, butyl glycidyl ether, phenyl glycidyl ether, cresyl glycidyl ether, polyethylene glycol diglycidyl ether, chloropropylene oxide, hydroquinones, bisnaphthol, 1-naphthols salicylic acid, benzoic acid, rosemary oil, epoxidized soybean oil, castor oil, olive oil, linseed oil, Magnesiumaluminumsilicate etc., can be one or more mixture; Described preservative is formaldehyde, benzoic acid, Sodium Benzoate etc., can be one or more mixture; Described antifreezing agent is ethylene glycol, propane diols, glycerine, urea, diethylene glycol (DEG), polyethylene glycol, sorbierite etc., can be one or more mixture.
After the invention has the advantages that lufenuron and worm hydrazides are mixed, the one, can widen control of insect spectrum, can be in a drug doublely control crop growth two or more simultaneous insects in the phase; The 2nd, can save the labour, reduce cost accounting; The 3rd, improve preventive effect or prolong the longevity of residure; The 4th, can overcome and delay insect and develop immunity to drugs, prolong the service life of pesticide species; The 5th, green pesticide form, environmental contamination reduction has alleviated toxicity.
Embodiment
The inventor is by a large amount of Seiving Tests, and discovery lufenuron and worm hydrazides are mixed diamond-back moth, beet armyworm, cabbage caterpillar are had synergistic function, and field test results shows that also the effect of mixture preparation is better than the use of single dose.
In order better to understand essence of an invention, below in conjunction with example technology contents of the present invention is described in detail, but content of the present invention do not limit to so, can not therefore be interpreted as the restriction to claim of the present invention.
The former medicine effective content of lufenuron used in following examples is 95%, and the former medicine effective content of used worm hydrazides is 95%.
Embodiment 1:
Prepare 5% lufenuron worm hydrazides (1% lufenuron+4% worm hydrazides) microemulsion:
Take by weighing the former medicine 1.06g of lufenuron, the former medicine 4.22g of worm hydrazides, agricultural newborn 2201#8g, dimethyl sulfoxide (DMSO) 10g, acetone 5g, epoxychloropropane 6g, sorbierite 1g, surplus deionized water.
Preparation process:
Former medicine, dimethyl sulfoxide (DMSO) and acetone are added together, make and be dissolved into even oil phase; The newborn 2201# of farming, epoxychloropropane, sorbierite and deionized water are dropped in the emulsion dispersion still, under high-speed stirred, form water; Then oil phase is dropped in the emulsion dispersion still, begin to stir under 500～15000 rev/mins rotating speed, mixing time is 0.5～1.5 hour, makes homogeneous, transparent, stable 5% lufenuron worm hydrazides microemulsion through high speed shear.
It is similar to Example 1 that following examples prepare the process of microemulsion.
Embodiment 2:
Prepare 20% lufenuron worm hydrazides (1% lufenuron+19% worm hydrazides) microemulsion, the mass ratio of each component is respectively:
The former medicine 1.06g of lufenuron, the former medicine 21.04g of worm hydrazides, lignosulfonates 10g, dimethyl sulfoxide (DMSO) 20g, acetone 5g, triphenyl phosphite 6g, glycerine 0.5g, surplus deionized water.
Embodiment 3:
Prepare 20% lufenuron worm hydrazides (0.4% lufenuron+19.6% worm hydrazides) microemulsion, the mass ratio of each component is respectively:
The former medicine 0.42g of lufenuron, the former medicine 20.63g of worm hydrazides, calcium dodecyl benzene sulfonate 10g, dimethyl sulfoxide (DMSO) 20g, cyclohexanone 10g, tolyl glycidic alcohol 6g, benzinum 1g, surplus deionized water.
Embodiment 4:
Prepare 5% lufenuron worm hydrazides (4.5% lufenuron+0.5% worm hydrazides) microemulsion, the mass ratio of each component is respectively:
The former medicine 4.74g of lufenuron, the former medicine 0.53g of worm hydrazides, agricultural newborn 400#8g, acetone 5g, dimethyl sulfoxide (DMSO) 5g, methyl alcohol 6g, sorbic acid 0.5g, surplus deionized water.
Embodiment 5:
Prepare 5% lufenuron worm hydrazides (1% lufenuron+4% worm hydrazides) suspending agent, the mass ratio of each component is respectively:
Take by weighing the former medicine 1.06g of lufenuron, the former medicine 4.22g of worm hydrazides, alkylnaphthalene sulfonate 5g, polyvinyl alcohol 4g, isoamyl alcohol 4g, castor oil 5g, Sodium Benzoate 0.2g, polyethylene glycol 0.5g, surplus deionized water.
Preparation process:
The former medicine that will contain first lufenuron and worm hydrazides mixes, adding in proportion alkylnaphthalene sulfonate fully stirs again, then adding successively each component such as polyvinyl alcohol, isoamyl alcohol, castor oil, Sodium Benzoate, polyethylene glycol, deionized water in the ratio of filling a prescription mixes, stir while adding evenly, ball milling is 2.0～4.0 hours in ball mill, so that the particle diameter of lufenuron and worm hydrazides all gets 5% lufenuron Tebufenozide suspending agent when 4 μ m are following.
It is similar to Example 5 that following examples prepare the process of suspending agent.
Embodiment 6:
Prepare 20% lufenuron worm hydrazides (1% lufenuron+19% worm hydrazides) suspending agent, the mass ratio of each component is respectively:
The former medicine 1.06g of lufenuron, the former medicine 21.04g of worm hydrazides, aliphatic alcohol sulfate 15g, sodium alginate 5g, isooctanol 4g, sodium sorbate 5g, benzoic acid 0.2g, sorbierite 0.5g, surplus running water.
Embodiment 7:
Prepare 20% lufenuron worm hydrazides (0.4% lufenuron+19.6% worm hydrazides) suspending agent, the mass ratio of each component is respectively:
The former medicine 0.42g of lufenuron, the former medicine 20.63g of worm hydrazides, lauryl alcohol polyethylene glycol oxide base ether sodium sulfate 15g, gum Arabic 5g, lauric acid 4g, rosemary oil 5g, formaldehyde 0.1g, ethylene glycol 0.5g, surplus deionized water.
Embodiment 8:
Prepare 5% lufenuron worm hydrazides (4.5% lufenuron+0.5% worm hydrazides) suspending agent, the mass ratio of each component is respectively:
The former medicine 4.74g of lufenuron, the former medicine 0.53g of worm hydrazides, alkylphenol polyoxyethylene 10g, methylcellulose 5g, stearic acid 4g, sodium sorbate 5g, benzoic acid 0.1g, glycerine 0.1g, surplus running water.
Determination of activity example 1: subjects is diamond-back moth (Plutella xylostella L) larva
Test method: with reference to People's Republic of China's agricultural industry criteria (" farm-chemical indoor determination test rule " insecticidal n Y/T1154.9-2008.
Carry out first preliminary experiment, according to the concentration range of the consequence devised reagent agent of preliminary experiment.Each single dose and preparation are established respectively 5 concentration, take 3 diamond-back moth in age (Plutella xylostella L) larvas as subjects.
The Potter spray-on process is adopted in this test.Filter paper is put into the culture dish that diameter is 9cm, add an amount of distilled water, make filter paper moistening, but ponding can not be arranged, get rid of the air between filter paper and the culture dish, it is for subsequent use to make filter paper be close to the culture dish bottom, with the moisturizing of moisturizing cotton balls.The atomisation pressure of Potter spray tower is stabilized in 1.47 * 10
5Pa, fog-spray nozzle clean 2 times with acetone first, clean 2 times with distilled water again.Utilize the Potter spray tower quantitatively to spray, spray value is 1mL, and 15 diamond-back moth 3 instar larvaes of every repetition take out diamond-back moth behind the sedimentation 1min after the spraying, put into the culture dish of fresh cabbage leaves and raise, and every ware is 1 repetition, and every concentration is established 4 repetitions.Contrast is processed with the aqueous acetone solution with amount.After processing, cleans 2 times with acetone, distilled water the complete drug concentration of every spray.At last culture dish is put into constant incubator (temperature: 25 ℃, relative moisture: 70%, periodicity of illumination L: D=16: 8h).72h investigation examination worm death condition after processing.
According to the data of investigation, calculate the lethality that each is processed, calculate the corrected mortality that each is processed with the AbbottShi formula, ask for virulence regression equation with DPS software, calculate LC
50, LC
95And LC
5095% confidence limit.According to the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun built agent, relatively the insecticidal effect of each mixture is estimated its synergistic effect.The common poison of built agent is that (CTC) 〉=120 show as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
Each single dose of table 1 and mixture thereof are to the toxicity test result of diamond-back moth 3 instar larvae 72h
According to the Toxicity Determination result, lufenuron: the worm hydrazides is 10: 1 to 1: 50 o'clock, co-toxicity coefficient (CTC) is all greater than 120, illustrate that each proportioning all has synergistic effect, especially lufenuron: the worm hydrazides is 1: 1 to 1: 19 o'clock, and co-toxicity coefficient (CTC) is all greater than 200, synergistic effect is obvious, lufenuron particularly: the worm hydrazides is 1: 19 o'clock, and co-toxicity coefficient (CTC) is greater than 300, and synergistic effect is obvious especially.
Determination of activity example 2: subjects is beet armyworm (Spodoptera exigua H ü bner) larva
Test method is with determination of activity example 1, and described examination worm is beet armyworm 3 instar larvaes.
Each single dose of table 2 and mixture thereof are to the toxicity test result of beet armyworm 3 instar larvae 72h
According to the Toxicity Determination result, lufenuron and worm hydrazides are to 72 hours LC of beet armyworm 3 instar larvaes
50Be respectively: 2.14,5.31mg/L.Lufenuron: the worm hydrazides is 10: 1 to 1: 50 o'clock, co-toxicity coefficient (CTC) shows to have synergistic effect, wherein lufenuron all greater than 120: the worm hydrazides is 1: 4,1: 10,1: 19 o'clock, co-toxicity coefficient (CTC) shows that all greater than 200 synergistic effect is obvious.
Determination of activity example 3:
Utilize among the embodiment 1,2 institute's preparaton to do following field control effectiveness test:
1, dispenser object
Diamond-back moth (Plutellaxylostella L) on the brassicaceous vegetable wild cabbage (Brassica oleracea var.capitata).
2, concentration design
1000,1500,2000 times of 5% lufenuron worm hydrazides ME dilutions; 1000,1500,2000 times of 20% lufenuron worm hydrazides ME dilutions; 1500 times of contrast medicament 5% lufenuron ME dilutions, 1500 times of 20% worm hydrazides ME dilutions.
3, test method
With reference to People's Republic of China's agricultural industry criteria (" pesticide field efficacy medicine test criterion (one) " GB/T17980.13---2000.
This test is experimental field carried out in Shenzhen Nuopuxin Agricultural Chemical Co., Ltd, and 4 repetitions are established in every processing, totally 36 residential quarters, every residential quarter area 10m
2, by at random district's group arrangement.5 points of parallel great-jump-forward sampling survey are adopted in every residential quarter, and every with bamboo let fixation mark 4 strains, investigate altogether 20 strains.Treat that diamond-back moth is that 2-3 sprays medicine and processes during age, every residential quarter spraying liquid 0.75kg, spray date is on April 7th, 2009, investigation insect population radix before the medicine was investigated residual borer population on the the 1st, 3,7,14 day behind the medicine.Adopt insect population decline rate methods analyst control efficiency, the new multipole of Deng Kenshi poor (DMRT) method is adopted in significance test, carries out significance analysis with DPS software.
4, results and analysis
(1) 5% lufenuron worm hydrazides microemulsion the results are shown in Table 3 to the field control effectiveness test 5% lufenuron worm hydrazides microemulsion of brassicaceous vegetable diamond-back moth to the field control effectiveness test of brassicaceous vegetable diamond-back moth, after the dispenser 1,3 day, the control efficiency that 5% lufenuron worm hydrazides ME dilution is 1500 times was in same level with the control efficiency of 1500 times of contrast medicament 5% lufenuron ME dilutions; After the dispenser 7,14 days, the control efficiency that 5% lufenuron worm hydrazides ME dilution is 1000 times is significantly higher than the control efficiency same period of 1500 times of contrast medicament 20% lufenuron ME dilutions, and the control efficiency that 5% lufenuron worm hydrazides ME dilution is 1500 times is not obvious with the control efficiency difference of 1500 times of contrast medicament 5% lufenuron ME dilutions, be in same level with the control efficiency same period of contrast medicament 20% worm hydrazides ME.
According to result of the test, the quick-acting of 5% lufenuron worm hydrazides ME is good, and is suitable with the quick-acting of 20% worm hydrazides ME; The lasting effect of 5% lufenuron worm hydrazides ME and 5% lufenuron ME difference are not obvious, but significantly better than the lasting effect of 20% worm hydrazides ME.
(2) 20% lufenuron worm hydrazides microemulsions are to the field control effectiveness test of brassicaceous vegetable diamond-back moth
20% lufenuron worm hydrazides microemulsion the results are shown in Table 4 to the field control effectiveness test of brassicaceous vegetable diamond-back moth, after the dispenser 1 day, the control efficiency that 20% lufenuron worm hydrazides ME dilution is 1000 times was significantly higher than the control efficiency of 1500 times of contrast medicament 5% lufenuron ME dilutions; After the dispenser 3 days, the control efficiency that 20% lufenuron worm hydrazides ME dilution is 1000 times was significantly higher than the control efficiency that 1500 times of contrast medicament 5% lufenuron ME dilutions and 20% worm hydrazides ME dilute 1500 times; After the dispenser 7,14 days, the control efficiency that 20% lufenuron worm hydrazides ME dilution is 1000 times is significantly higher than the control efficiency same period that 1500 times of contrast medicament 5% lufenuron ME dilutions and 20% worm hydrazides ME dilute 1500 times, the control efficiency that 20% lufenuron worm hydrazides ME dilution is 1500 times is not obvious with the control efficiency difference same period of 1500 times of contrast medicament 5% lufenuron ME dilutions, is in same level with the control efficiency same period that contrasts 1500 times of medicament 20% worm hydrazides ME dilutions.
According to result of the test, the quick-acting of 20% lufenuron worm hydrazides ME is good, and is suitable with the quick-acting of 20% worm hydrazides ME; The lasting effect of 20% lufenuron worm hydrazides ME is significantly better than the lasting effect of contrast medicament 5% lufenuron ME difference and 20% worm hydrazides ME.
Comprehensive above-mentioned field control effectiveness test result shows that institute's preparaton 5% lufenuron worm hydrazides ME, 20% lufenuron worm hydrazides ME among the embodiment 1,2 are better than the use of single dose in actual applications, can prolong drug effect, reduces the medication number of times; In addition, institute's preparaton is microemulsion, and used organic solvent is less, has reduced the pollution of organic solvent to environment, has alleviated penetrating odor, to the also greatly raising of safety of crop.
Claims (5)
1. insecticidal/acaricidal composition is characterized in that: it is equipped with additive compound and forms take lufenuron and worm hydrazides as active component, and wherein the ratio of quality and the number of copies of lufenuron and worm hydrazides is 10: 1～1: 50.
2. described insecticidal/acaricidal composition according to claim 1, it is characterized in that: the ratio of quality and the number of copies of lufenuron and worm hydrazides is 1: 1～1: 20 in the composition.
3. claim 1 or 2 described insecticidal/acaricidal compositions, it is characterized in that: composition is mixed with microemulsion, suspending agent, aqueous emulsion, water dispersible granules, wetting powder or missible oil.
4. insecticidal/acaricidal composition according to claim 3, insecticidal/acaricidal composition are used for insect or the evil mite on control Lepidoptera, Homoptera, thrips, the Acarina.
5. insecticidal/acaricidal composition according to claim 4, insecticidal/acaricidal composition are used for control diamond-back moth, beet armyworm, striped rice borer, cabbage caterpillar, prodenia litura, lima bean pod borer, cotton bollworm, oriental tobacco budworm, tea geometrid, tea caterpillar, trialeurodes vaporariorum, thrips, rust mite.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200910146853 CN101637172B (en) | 2009-06-12 | 2009-06-12 | Insecticidal/acaricidal composition having lufenuron and tebufenozide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200910146853 CN101637172B (en) | 2009-06-12 | 2009-06-12 | Insecticidal/acaricidal composition having lufenuron and tebufenozide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101637172A CN101637172A (en) | 2010-02-03 |
| CN101637172B true CN101637172B (en) | 2013-03-27 |
Family
ID=41612497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200910146853 Active CN101637172B (en) | 2009-06-12 | 2009-06-12 | Insecticidal/acaricidal composition having lufenuron and tebufenozide |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101637172B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106172402A (en) * | 2012-03-14 | 2016-12-07 | 陕西韦尔奇作物保护有限公司 | A kind of composition pesticide of containing chromafenozide |
| CN104419559A (en) * | 2013-08-22 | 2015-03-18 | 南通恒鼎重型机床有限公司 | Detergent specially used for removing acarids |
| GB201416633D0 (en) * | 2014-09-19 | 2014-11-05 | Pharmaq As | Formulation |
| CN107646837A (en) * | 2016-07-26 | 2018-02-02 | 北京易丰源生物科技有限公司 | A kind of green and environment-friendly pesticide spray adjuvantses composition |
| CN107646838A (en) * | 2016-07-26 | 2018-02-02 | 北京易丰源生物科技有限公司 | A kind of edible glue class pesticide spray assistant composition |
| CN110583653A (en) * | 2019-10-15 | 2019-12-20 | 中国农业科学院棉花研究所 | Insecticidal composition and application thereof |
| CN111990398A (en) * | 2020-07-27 | 2020-11-27 | 南京太化化工有限公司 | Auxiliary agent for suspending agent and cyromazine suspending agent |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1364413A (en) * | 2002-02-07 | 2002-08-21 | 江苏省农药研究所 | Composition with pesticide and miticide actility |
| CN1788560A (en) * | 1995-05-24 | 2006-06-21 | 拜尔公司 | Pesticide combination |
| CN101018482A (en) * | 2004-07-20 | 2007-08-15 | 拜尔农作物科学股份公司 | Insecticidal agents based on selected insecticides and safeners |
-
2009
- 2009-06-12 CN CN 200910146853 patent/CN101637172B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1788560A (en) * | 1995-05-24 | 2006-06-21 | 拜尔公司 | Pesticide combination |
| CN1364413A (en) * | 2002-02-07 | 2002-08-21 | 江苏省农药研究所 | Composition with pesticide and miticide actility |
| CN101018482A (en) * | 2004-07-20 | 2007-08-15 | 拜尔农作物科学股份公司 | Insecticidal agents based on selected insecticides and safeners |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101637172A (en) | 2010-02-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101637172B (en) | Insecticidal/acaricidal composition having lufenuron and tebufenozide | |
| CN101836641B (en) | Oil-suspending agent disinfestation composition containing spinosyns and emamectin benzoate | |
| CN101817711A (en) | Emamectin benzoate-algae slow release type water dispersible granular insecticide and preparation method | |
| CN105532714A (en) | Safe, environment-friendly and efficient insecticidal composition and use thereof | |
| CN102113509B (en) | Insecticidal composition containing bifenthrin and emamectin benzoate | |
| CN101984828A (en) | Compound pesticide | |
| CN102228044B (en) | Insecticidal composition containing sufluoxime | |
| CN102228056B (en) | Pesticide composition containing sulfur-fluorine oxime ether and part of organophosphorus pesticides | |
| CN102484994B (en) | Synergy composition of matrine and chlorantraniliprole | |
| CN101731228A (en) | Fenazaquin-containing acaricidal composition | |
| CN101406199A (en) | Insecticidal composition containing emamectin-benzoate | |
| CN101485329A (en) | Agricultural chemical composition for disinsection and use thereof | |
| CN102630676B (en) | A kind of Efficient insecticidal composition | |
| CN102334488B (en) | Insect-killing and disease-preventing suspension seed coating formulation | |
| CN101653126B (en) | Mite-killing composition containing fenazaquin | |
| CN104522006B (en) | A kind of preventing and treating Lepidoptera and homoptera pest compositions | |
| CN102792961B (en) | Insecticidal composition and insecticidal pesticide | |
| CN102484991B (en) | Synergic farm pesticide composition of ivermectin and tea saponin | |
| CN109042657A (en) | A kind of compound acaricide and its preparation method and application controlling phytophagous harmful mite | |
| CN104082323B (en) | There is the insect-killing composition of synergism | |
| CN109805031A (en) | The bollworm virus Pesticidal combination and agricultural insecticide of containing chlorantraniliprole | |
| CN101543224B (en) | Insecticidal composition containing triaguron and chlorpyrifos | |
| CN102217596A (en) | Blended pesticide preparation of TDS and tebufenozide | |
| CN101653134A (en) | Mite-killing composition containing fenazaquin | |
| CN105340950A (en) | Insecticide composition containing o-phenylenediamine pesticide and efficient cyhalothrin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang Patentee after: Shenzhen Novozon Crop Science Co.,Ltd. Country or region after: China Address before: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang Patentee before: SHENZHEN NOPOSION AGROCHEMICALS Co.,Ltd. Country or region before: China |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240307 Address after: 266000 Qianduobu Village, Jiangshan Town, Laixi City, Qingdao, Shandong Province (Busan Industrial Park) Patentee after: QINGDAO STAR CROPSCIENCE Co.,Ltd. Country or region after: China Address before: 518102 No. 113 Reservoir Road, Baoan District, Guangdong, Shenzhen, Xixiang Patentee before: Shenzhen Novozon Crop Science Co.,Ltd. Country or region before: China |