CN101631850B - 增加和转移造血干细胞的方法 - Google Patents
增加和转移造血干细胞的方法 Download PDFInfo
- Publication number
- CN101631850B CN101631850B CN2008800077612A CN200880007761A CN101631850B CN 101631850 B CN101631850 B CN 101631850B CN 2008800077612 A CN2008800077612 A CN 2008800077612A CN 200880007761 A CN200880007761 A CN 200880007761A CN 101631850 B CN101631850 B CN 101631850B
- Authority
- CN
- China
- Prior art keywords
- hours
- cells
- application
- hscs
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 *C(C(C*CC(COC(*)=O)OC(*)=O)N*)=O Chemical compound *C(C(C*CC(COC(*)=O)OC(*)=O)N*)=O 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88416207P | 2007-01-09 | 2007-01-09 | |
| US60/884,162 | 2007-01-09 | ||
| US88989307P | 2007-02-14 | 2007-02-14 | |
| US60/889,893 | 2007-02-14 | ||
| US93856407P | 2007-05-17 | 2007-05-17 | |
| US60/938,564 | 2007-05-17 | ||
| US1324307P | 2007-12-12 | 2007-12-12 | |
| US61/013,243 | 2007-12-12 | ||
| PCT/US2008/050644 WO2008086426A2 (en) | 2007-01-09 | 2008-01-09 | Methods for increasing and mobilizing hematopoietic stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101631850A CN101631850A (zh) | 2010-01-20 |
| CN101631850B true CN101631850B (zh) | 2013-12-04 |
Family
ID=39609361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008800077612A Expired - Fee Related CN101631850B (zh) | 2007-01-09 | 2008-01-09 | 增加和转移造血干细胞的方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20100055077A1 (enExample) |
| EP (1) | EP2115124B1 (enExample) |
| JP (1) | JP5389666B2 (enExample) |
| KR (1) | KR101493474B1 (enExample) |
| CN (1) | CN101631850B (enExample) |
| BR (1) | BRPI0806557A2 (enExample) |
| CA (1) | CA2675032A1 (enExample) |
| EA (1) | EA018983B1 (enExample) |
| IL (1) | IL199766A (enExample) |
| MX (1) | MX2009007391A (enExample) |
| NZ (2) | NZ578928A (enExample) |
| SG (1) | SG177959A1 (enExample) |
| WO (1) | WO2008086426A2 (enExample) |
| ZA (1) | ZA200905378B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2612102C (en) | 2005-06-13 | 2016-02-09 | Cleveland Biolabs, Inc. | Methods of protecting against apoptosis using lipopeptides |
| DK2032701T3 (da) * | 2006-06-23 | 2014-02-10 | Alethia Biotherapeutics Inc | Polynukleotider og polypeptider, der er inddraget i cancer |
| JP5781932B2 (ja) | 2008-11-03 | 2015-09-24 | アレシア・バイオセラピューティクス・インコーポレーテッド | 腫瘍抗原の生物活性を特異的にブロックする抗体 |
| US20130039882A1 (en) * | 2009-10-28 | 2013-02-14 | Henry Ford Health System | Method to mitigate injury from radiation exposure |
| EP2338521A1 (en) * | 2009-12-28 | 2011-06-29 | Helmholtz-Zentrum für Infektionsforschung GmbH | Lipopeptide- and lipoprotein-conjugates and its use |
| US20130230580A1 (en) * | 2010-09-14 | 2013-09-05 | Paul S. Frenette | Administration of SNS Neuroprotective Agents to Promote Hematopoietic Regeneration |
| EP2691421B1 (en) | 2011-03-31 | 2016-11-09 | Alethia Biotherapeutics Inc. | Antibodies against kidney associated antigen 1 and antigen binding fragments thereof |
| EA201992513A1 (ru) | 2012-01-09 | 2020-05-31 | Адс Терапьютикс Са | Способ лечения рака груди |
| WO2013149064A1 (en) * | 2012-03-30 | 2013-10-03 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Uridine diphosphate compounds as mobilizers of hematopoietic progenitor cells |
| EP2838614B1 (en) | 2012-04-20 | 2019-09-11 | GB006, Inc. | Compositions for regulating integrins |
| CN104027791B (zh) * | 2013-03-06 | 2016-08-10 | 浙江海正药业股份有限公司 | 药物组合物 |
| JP2016518415A (ja) * | 2013-10-21 | 2016-06-23 | アドバンスド ニューロリジェネレイティブ セラピーズ エルエルシー | 加齢と疾患免疫機能障害と細胞老化とをリンパ球系幹細胞で修復する方法、及び治療使用のためのそれらの再適用する方法 |
| CN104744563B (zh) * | 2013-12-27 | 2019-02-26 | 中国人民解放军军事医学科学院毒物药物研究所 | 端基具有亲脂性结构的线性脂肽、其制备方法及用途 |
| WO2016073733A1 (en) * | 2014-11-06 | 2016-05-12 | Cleveland Biolabs, Inc. | Methods of treating cancer using lipopeptides |
| US20210189344A1 (en) * | 2018-08-30 | 2021-06-24 | The Regents Of The University Of California | Mobilization and collection of peripheral blood hematopoietic stem cells from deceased donors |
| CN112851755B (zh) * | 2021-01-13 | 2023-09-01 | 中国人民解放军军事科学院军事医学研究院 | 一种线性脂肽化合物及其制备方法与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US5192553A (en) * | 1987-11-12 | 1993-03-09 | Biocyte Corporation | Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use |
| DE19822820A1 (de) * | 1998-05-20 | 1999-11-25 | Biotechnolog Forschung Gmbh | Pharmazeutisches Präparat zur Wundbehandlung |
| CA2612102C (en) * | 2005-06-13 | 2016-02-09 | Cleveland Biolabs, Inc. | Methods of protecting against apoptosis using lipopeptides |
| CA2659337A1 (en) * | 2006-08-07 | 2008-02-14 | Genzyme Corporation | Combination therapy |
-
2008
- 2008-01-09 NZ NZ578928A patent/NZ578928A/xx not_active IP Right Cessation
- 2008-01-09 WO PCT/US2008/050644 patent/WO2008086426A2/en not_active Ceased
- 2008-01-09 EP EP08705809.5A patent/EP2115124B1/en not_active Not-in-force
- 2008-01-09 SG SG2012001392A patent/SG177959A1/en unknown
- 2008-01-09 CN CN2008800077612A patent/CN101631850B/zh not_active Expired - Fee Related
- 2008-01-09 KR KR20097016496A patent/KR101493474B1/ko not_active Expired - Fee Related
- 2008-01-09 EA EA200900806A patent/EA018983B1/ru not_active IP Right Cessation
- 2008-01-09 JP JP2009545662A patent/JP5389666B2/ja not_active Expired - Fee Related
- 2008-01-09 MX MX2009007391A patent/MX2009007391A/es active IP Right Grant
- 2008-01-09 BR BRPI0806557-8A2A patent/BRPI0806557A2/pt active Search and Examination
- 2008-01-09 CA CA002675032A patent/CA2675032A1/en not_active Abandoned
- 2008-01-09 US US12/522,606 patent/US20100055077A1/en not_active Abandoned
- 2008-01-09 NZ NZ603805A patent/NZ603805A/en not_active IP Right Cessation
-
2009
- 2009-07-08 IL IL199766A patent/IL199766A/en not_active IP Right Cessation
- 2009-07-31 ZA ZA200905378A patent/ZA200905378B/xx unknown
-
2013
- 2013-07-02 US US13/933,954 patent/US20140045747A1/en not_active Abandoned
-
2015
- 2015-03-04 US US14/638,888 patent/US20150174195A1/en not_active Abandoned
Non-Patent Citations (1)
| Title |
|---|
| 胡晶等.当归多糖对小鼠外周血造血干细胞动员作用的研究.《中草药》.2006,第37卷(第12期),摘要. * |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ578928A (en) | 2013-03-28 |
| AU2008204836A1 (en) | 2008-07-17 |
| WO2008086426A8 (en) | 2009-07-30 |
| KR101493474B1 (ko) | 2015-02-16 |
| EA018983B1 (ru) | 2013-12-30 |
| US20100055077A1 (en) | 2010-03-04 |
| SG177959A1 (en) | 2012-02-28 |
| BRPI0806557A2 (pt) | 2014-04-15 |
| US20140045747A1 (en) | 2014-02-13 |
| IL199766A (en) | 2015-01-29 |
| EA200900806A1 (ru) | 2010-08-30 |
| EP2115124A2 (en) | 2009-11-11 |
| WO2008086426A2 (en) | 2008-07-17 |
| ZA200905378B (en) | 2010-05-26 |
| WO2008086426A3 (en) | 2008-12-18 |
| CA2675032A1 (en) | 2008-07-17 |
| JP5389666B2 (ja) | 2014-01-15 |
| KR20090108703A (ko) | 2009-10-16 |
| MX2009007391A (es) | 2009-08-13 |
| NZ603805A (en) | 2014-03-28 |
| JP2010515748A (ja) | 2010-05-13 |
| US20150174195A1 (en) | 2015-06-25 |
| HK1134835A1 (en) | 2010-05-14 |
| EP2115124A4 (en) | 2012-05-30 |
| EP2115124B1 (en) | 2016-03-16 |
| CN101631850A (zh) | 2010-01-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101631850B (zh) | 增加和转移造血干细胞的方法 | |
| EP2566954B1 (en) | Immunotherapy using redirected allogeneic cells | |
| Merluzzi et al. | Expansion of cyclophosphamide-resistant cytotoxic precursors in vitro and in vivo by purified human interleukin 2. | |
| JP2022088551A (ja) | 増殖造血幹細胞/前駆細胞集団の利用 | |
| AU2179392A (en) | Method for improving autologous transplantation | |
| EP1030675A2 (en) | Treatment of hematologic disorders | |
| BR112020011186A2 (pt) | regimes de dosagem para a mobilização de células-tronco e progenitoras hematopoiéticas | |
| Basser et al. | Rapid hematopoietic recovery after multicycle high-dose chemotherapy: enhancement of filgrastim-induced progenitor-cell mobilization by recombinant human stem-cell factor. | |
| JP2023505192A (ja) | 養子細胞療法としての遺伝子操作された二重陰性t細胞 | |
| US5637323A (en) | Method of mobilizing pluripotential hematopoietic stem cells with IL-7 | |
| HK1134835B (en) | Methods for increasing and mobilizing hematopoietic stem cells | |
| AU2008204836B2 (en) | Methods for increasing and mobilizing hematopoietic stem cells | |
| US20220401481A1 (en) | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells | |
| JP4106488B2 (ja) | 同種移植片に対する免疫寛容の誘導および/または白血病処置のための、幹細胞およびcd6枯渇幹細胞の使用 | |
| EP4308694A1 (en) | Dosing regimens for hematopoietic stem cell mobilization for stem cell transplants in multiple myeloma patients | |
| Corbí | Pathogen recognition by dendritic cells: Role of C-type lectins | |
| Macintyre et al. | Splenic natural cytotoxic activity is enhanced during growth of a murine fibrosarcoma | |
| Safa et al. | Salt Augments the Alloimmune Response and Accelerates Allograft Rejection.: Abstract# D2788 | |
| Khanna et al. | Hematopoietic growth factors in transplantation: Biology and applications |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1134835 Country of ref document: HK |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1134835 Country of ref document: HK |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131204 Termination date: 20170109 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |