CN101625369B - Intelligent sample processor - Google Patents
Intelligent sample processor Download PDFInfo
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- CN101625369B CN101625369B CN 200810029387 CN200810029387A CN101625369B CN 101625369 B CN101625369 B CN 101625369B CN 200810029387 CN200810029387 CN 200810029387 CN 200810029387 A CN200810029387 A CN 200810029387A CN 101625369 B CN101625369 B CN 101625369B
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Abstract
The invention discloses an intelligent sample processor, and in particular relates to a medical instrument capable of helping doctors to finish certain mechanical work. The intelligent sample processor comprises a system control device, a pipette device, sample transfer equipment and a sample transfer frame, wherein a user drives the pipette device to perform related operation through a command input through the system control device; the pipette device comprises a large hand, a small hand, a supporting plate and two fleeing prevention pressing plates, wherein the large hand, the small hand and the supporting plate cooperate with each other to finish the pipetting operation; the sample transfer equipment comprises a pipette, a sample bottle and a centrifuge tube; and the sample transfer frame comprises a pipette limit hole, a sample bottle limit hole, a centrifuge tube limit hole and a transfer frame limit hole. The intelligent sample processor is suitable to be used in large hospitals when sampled liquid of patients is transferred so as to avoid excessive personnel input in the mechanical work.
Description
Technical field
The invention belongs to medical instruments field, specifically, relate to a kind of instrument that can help the doctor to complete some machine works.
Background technology
To needing the biological sample that the sample layering is processed to shift, by artificial suction method, there were like this problems such as speed is inhomogeneous, layered effect is undesirable, labor intensive material resources fully in the past.Also there are in recent years some similar products of thinking head it off to come out, too high but existence requires pipettor physical dimension, otherwise folder is tight or pipettor pushes away to enter; Thickness to the Sample preservation bottle cap is extremely strict, and is thicker a little, and the most advanced and sophisticated just thorn of pipettor is not worn bottle cap; Complete machine structure is unreasonable, operate loaded down with trivial details, and the easy problem of card-maker phenomenon etc.This intelligent sample disposal machine adopts the intelligent microcomputer disposal system, high-precision photoelectric positioning system carries out accurate motion control to guide rail, adjustable pipettor clamp device adapts to dissimilar pipettor, the program of plug bottle has better solved the problem of the plug bottle difficulty of sample bottle cap became uneven in batches, said device features rational structure, simple to operate.The automatic batch of having realized sample shifts.Be mainly used in cervical cell and centrifugal in earlier stage process, with the sample in specimen bottle carry out quantitatively, being transferred in centrifuge tube at the uniform velocity.Make reagent and sample form the best centrifugal effect of layering, guarantee that centrifugal rear collection has the cell of diagnostic value, removes the interfering components in sample simultaneously.
Summary of the invention
The invention discloses a kind of intelligent sample processor, it comprises system control device, pipette device, sample transfer equipment and specimen transferring frame.
Described system control device comprises a Switching Power Supply, 3 drivers, 3 motors, a relay, 2 Timing Belts, display screen and keyboards, and the order that system control device is mainly inputted by the user drives pipette device and carries out associative operation.Wherein Switching Power Supply is two-phase gauge tap power supply, and one is 24v driving, another 5v signal driver power supply; Driver, motor,, relay, a Timing Belt and large palmistry connect, control large hand and do vertical movement; A driver, a motor, a Timing Belt and little palmistry connect, and control little hand and do vertical movement; A driver, a motor are connected with supporting plate, control supporting plate and move horizontally; Its repeat circuit is to prevent in the situation that have a power failure, and large hand can vertically fall; Keyboard comprise withdraw from, increase, arrange, move, a left side, minimizing, the right side and Pause key.
Described pipette device comprises that a large hand, little hand, supporting plate and two only alter pressing plate, pipette device accept system control device signal, carry out pipetting.
Large hand comprises again large hand support, 2 large hand sliding eyes, 2 little hand guide rods, pipettor clamp device, 4 trimmers and 4 location spiral pins, large hand is controlled on large hand guide rod by Timing Belt does vertical movement, and can be fit to pipettor with different-diameter by trimmer and location spiral pin and pipettor clamp device; Little hand comprises little hand sliding eye, little hand pressure board and 223 belt hooks, and little hand is done vertical movement by Timing Belt on little hand guide rod, and when the pipettor height is inconsistent, can be consistent by the extruding downwards of little hand pressure board; Two effects of only altering pressing plate are: after pipettor inserted specimen bottle, another pushed down specimen bottle between 3,4 specimen bottles between 1,2 specimen bottles only to alter one of pressing plate, prevents specimen bottle pull-up together; Supporting plate comprises slightly with one of location stopper slot.
Described sample transfer equipment comprises pipettor, specimen bottle and centrifuge tube.
Described specimen transferring frame comprises pipettor spacing hole, specimen bottle spacing hole, centrifuge tube spacing hole and shifts the frame spacing hole, and specimen transferring frame is by transfer frame spacing hole and supporting plate) on stopper slot be fixed on supporting plate.4 spacing holes are drawn together in the every package of specimen transferring frame, every row comprise 9 spacing holes, every 3 spacing holes are one group, each group comprises again a pipettor spacing hole, specimen bottle spacing hole and centrifuge tube spacing hole, and the every row pipettor of every row spacing hole, specimen bottle spacing hole are consistent with the height of centrifuge tube spacing hole.Specimen transferring frame is done tangential movement together by supporting plate.
The driver that described specimen bottle movable stand connects is programmed to: after pipettor injects the centrifuge tube center, moving 0 to 6mm distance after the specimen bottle movable stand can regulate, purpose makes the outlet of pipettor be close to the tube wall of centrifuge tube, sample is flowed down along the tube wall of centrifuge tube, rather than enter centrifuge tube to drip the shape form.
All right every row is inconsistent for the height of the specimen bottle spacing hole of described specimen transferring frame, and every row are consistent, and every row's difference in height is within 5 millimeters.
The transfer frame spacing hole of described specimen transferring frame can also adopt diplopore and lock plate structure, and specimen transferring frame can not moved with working direction up and down
Beneficial effect of the present invention: because syringe clamping part of the present invention is provided with parts 211 trimmers that can regulate, reach even the diameter of syringe has the difference of positive and negative 1mm also can regulate this clamping part the effect that clamps syringe; The present invention is provided with the little hand pressure board 221 of syringe, even the push rod of syringe does not push over reference position (when having more syringe to dispatch from the factory, push rod does not push over reference position), little hand pressure board just begins to carry out later program after also can first pushing over reference position to it; Because being provided with, the present invention only alters pressing plate, so after pipettor inserted specimen bottle, another pushed down specimen bottle between 3,4 specimen bottles between 1,2 specimen bottles only to alter one of pressing plate, prevents specimen bottle pull-up together; Pipettor of the present invention is after injecting the centrifuge tube center, move 0 to 6mm distance (can regulate) after software-driven specimen bottle movable stand, purpose makes the outlet of pipettor be close to the tube wall of centrifuge tube, sample is flowed down along the tube wall of centrifuge tube, rather than entering centrifuge tube to drip the shape form, this is conducive to improve the layered effect of sample.
Description of drawings
Fig. 1 is the intelligent sample processor system architecture diagram;
Fig. 2 a, b are the intelligent sample processor schematic diagram;
Fig. 3 is large hand structural drawing;
Fig. 4 is little hand structural drawing;
Fig. 5 is lock plate structure figure;
Fig. 6 is display screen and button schematic diagram;
Fig. 7 is sample jump operation process flow diagram.
Embodiment
Below in conjunction with accompanying drawing, the present invention is further set forth.
As shown in Figure 1, the invention discloses a kind of intelligent sample processor, it comprises system control device 1, pipette device 2 and sample transfer equipment 4 and specimen transferring frame 3.
System control device 1 comprises a Switching Power Supply 11,3 drivers 121/122/123,3 motors 131/132/133, a relay 14,2 Timing Belts 151/152, display screen 16 and keyboards 17, the order that system control device 1 is mainly inputted on button 17 by the user drives pipette device 2 and carries out associative operation.Wherein Switching Power Supply 11 is two-phase gauge tap power supply, and one is 24v power drive power supply, another 5v signal driver power supply; Driver 121, motor 131, relay 14, Timing Belt 151 and large hand 21 are connected, and control large hand 21 and do vertical movement; Driver 122, motor 132, Timing Belt 152 and little hand 22 are connected, and control little hand 22 and do vertical movement; Driver 123, motor 132 and supporting plate 24 are connected, and control supporting plate 24 and move horizontally; In the situation that has a power failure, hand 21 can vertically fall its repeat circuit 14 greatly in order to prevent; As shown in Figure 6 keyboard comprise withdraw from, increase, arrange, move, a left side, minimizing, the right side and Pause key.
Pipette device 2 comprises a large hand 21, little hand 22, only alters pressing plate 23 and a supporting plate 24, pipette device 2 accept system control device 1 signal, carry out pipetting.
As shown in Figure 3, large hand 21 comprises again large hand support 214,2 large hand sliding eyes 212,2 little hand guide rods 213, pipettor clamp device 215,4 trimmers 211 and 4 location spiral pins 216, large hand 21 is controlled on large hand guide rod by Timing Belt 151 does vertical movement, and can be fit to pipettor with different-diameter by trimmer 211 and location spiral pin 216 and pipettor clamp device 215; As shown in Figure 4, little hand 22 comprises little hand sliding eye 222, little hand pressure board 221 and (223 belt hook), little hand 22 is done vertical movement by Timing Belt 152 on little hand guide rod 213, and when pipettor 31 is highly inconsistent, can be consistent by the extruding downwards of little hand pressure board; What only alter pressing plate 23 employings is U-shaped two structure that refers to, after pipettor inserts specimen bottle, only alters pressing plate between 1,2 specimen bottles for one, and another pushes down specimen bottle between 3,4 specimen bottles, prevent specimen bottle pull-up together; Supporting plate comprise a location slightly 241, base plate 243 and a stopper slot 242 (as shown in Figure 2).
The sample transfer equipment comprises pipettor 31, specimen bottle 32 and centrifuge tube 33.
Based on above-mentioned explanation, specimen transferring frame can also adopt every row specimen bottle height consistent, the highly inconsistent structure of every row, dynamics when can reduce like this syringe insertion specimen bottle sampling basis, thereby reduce requirement and loss to motor, the difference in height of every row's specimen bottle is within 5 millimeters.
Because specimen transferring frame adopts the spacing pore structure of above-mentioned single hole, in the larger situation that meets obstructions, easily come off, therefore the present invention also is provided with other diplopore in conjunction with lock plate structure, as shown in Figure 5, and when inserting locking plate 442, when register pin 441 is fixed on hole 444, just can shift frame by fixed sample.
The above-mentioned explanation that is based on hardware, design the present invention of software mainly realizes by be written into different drivers on driver, and be that instrument work the time all first is kept in computer to each control procedure information, fall suddenly restore electricity again after, instrument can be followed last final step and complete remaining operation, software also can be arranged to keep last final step after restoring electricity, and is processed by demand by operating personnel.
Be illustrated in figure 7 as sample jump operation process flow diagram.
The driver that the specimen bottle movable stand connects is programmed to: after pipettor injects the centrifuge tube center, moving 0 to 6mm distance after the specimen bottle movable stand can regulate, purpose makes the outlet of pipettor be close to the tube wall of centrifuge tube, sample is flowed down along the tube wall of centrifuge tube, rather than enter centrifuge tube to drip the shape form.
Keypress function is introduced:
| Button | Running status | Coordinate arranges |
| RUN | Beginning | Point to next step |
| SET | Arrange/be kept at interface of main menu and press SET and enter setup menu and press the SET key at the setup menu state and preserve parameter, | Point to next step, and preserve coordinate figure |
| Return to master menu | ||
| ESC | Withdraw from/reset | Cancel the parameter of Set For Current, return to master menu |
| PAUSE | Suspend | Suspend |
| INC | Increase: the conversion between ON/OFF | On move: Y1, Y2, when the X3 coordinate arranges |
| DEC | Reduce: the conversion between ON/OFF | Move down: Y1, Y2, when the X3 coordinate arranges |
| left | Move to left: cursor movement is to a upper row | Retreat: X0, when the X3 coordinate arranges |
| right | Move to right: cursor movement is to next row | Advance: X0, when the X3 coordinate arranges |
Claims (5)
1. intelligent sample processor, it comprises system control device (1), pipette device (2), sample transfer equipment (3) and specimen transferring frame (4); System control device (1) comprises a Switching Power Supply (11), 3 drivers (121,122,123), 3 motors (131,132,133), a relay (14), 2 Timing Belts (151,152), display screen (16) and keyboard (17), the order that system control device is mainly inputted by the user drives pipette device (2) and carries out associative operation; Pipette device (2) comprises that a large hand (21), a little hand (22), two only alter pressing plate (23) and a supporting plate (24), and pipette device (2) is accepted signal, the executable operations of system control device; Sample transfer equipment (3) comprises pipettor (31), specimen bottle (32) and centrifuge tube (33); Specimen transferring frame (4) comprises pipettor spacing hole (41), specimen bottle spacing hole (42), centrifuge tube spacing hole (43) and shifts frame spacing hole (44), specimen transferring frame (4) is fixed on supporting plate by pickup groove (242) and spacing slightly (241) of shifting on frame spacing hole (44) and supporting plate (24), 4 spacing holes are drawn together in the every package of specimen transferring frame, every row comprise 9 spacing holes, every 3 spacing holes are one group, and each group comprises again a pipettor spacing hole, specimen bottle spacing hole and centrifuge tube spacing hole; It is characterized in that, only alter pressing plate for described two, one between 1,2 row specimen bottles, another are between 3,4 row specimen bottles.
2. intelligent sample processor according to claim 1, it is characterized in that, the every row pipettor of the every row spacing hole (41) of described specimen transferring frame (4), specimen bottle spacing hole (42), centrifuge tube spacing hole (43) are consistent with the height that shifts frame spacing hole (44).
3. intelligent sample processor according to claim 1, is characterized in that, the every row of height of the specimen bottle spacing hole (42) of described specimen transferring frame (4) is inconsistent, and every row are consistent, and every row's difference in height is within 5 millimeters.
4. intelligent sample processor according to claim 1, is characterized in that, the transfer frame spacing hole (44) of described specimen transferring frame (4) adopts diplopore and lock plate structure.
5. intelligent sample processor according to claim 1, is characterized in that, the keyboard (17) of described system control device (1) comprise withdraw from, increase, arrange, move, a left side, minimizing, the right side and Pause key.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810029387 CN101625369B (en) | 2008-07-11 | 2008-07-11 | Intelligent sample processor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200810029387 CN101625369B (en) | 2008-07-11 | 2008-07-11 | Intelligent sample processor |
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| CN101625369A CN101625369A (en) | 2010-01-13 |
| CN101625369B true CN101625369B (en) | 2013-06-19 |
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| CN 200810029387 Active CN101625369B (en) | 2008-07-11 | 2008-07-11 | Intelligent sample processor |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI481845B (en) * | 2012-12-27 | 2015-04-21 | Ind Tech Res Inst | Processing device for testing sample |
| CN105013551B (en) * | 2015-08-18 | 2017-01-25 | 苏州大学 | Intelligent pipettor support |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2655230Y (en) * | 2003-11-20 | 2004-11-10 | 陈玉昆 | Chemical reactor for multi-element automatic chemical analyzer |
| CN101021455A (en) * | 2007-03-22 | 2007-08-22 | 广州安必平医药科技有限公司 | Slide-making staining machine and method for slide-making staining method |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2655230Y (en) * | 2003-11-20 | 2004-11-10 | 陈玉昆 | Chemical reactor for multi-element automatic chemical analyzer |
| CN101021455A (en) * | 2007-03-22 | 2007-08-22 | 广州安必平医药科技有限公司 | Slide-making staining machine and method for slide-making staining method |
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| CN101625369A (en) | 2010-01-13 |
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Owner name: GUANGZHOU LBP MEDICINE SCIENCE + TECHNOLOGY CO., L Free format text: FORMER NAME: GUANGZHOU ANBIPING MEDICAL SCIENCE + TECHNOLOGY CO., LTD. |
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Address after: Three road 510665 in Guangdong Province, Guangzhou Nanxiang high tech Industrial Development Zone No. 11 self building 7 Patentee after: Guangzhou LBP Medicine Science & Technology Co., Ltd. Address before: 2804, room 510300, B, Hua Ting, 1026 Binjiang East Road, Guangzhou, Guangdong Patentee before: Guangzhou Anbiping Medical Science & Technology Co., Ltd. |