CN101624616B - 用于检测大肠癌的基因组合及其基因芯片 - Google Patents
用于检测大肠癌的基因组合及其基因芯片 Download PDFInfo
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- CN101624616B CN101624616B CN2007101957941A CN200710195794A CN101624616B CN 101624616 B CN101624616 B CN 101624616B CN 2007101957941 A CN2007101957941 A CN 2007101957941A CN 200710195794 A CN200710195794 A CN 200710195794A CN 101624616 B CN101624616 B CN 101624616B
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- large bowel
- colorectal cancer
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编号 | 名称 | 引物(5’-3’) | 基因片段长 度(bp) |
1 | VIP | CTCCTTGTGCTCCTGAC | 200 |
CTGCTCCTCTTTCCATTC | |||
2 | C2 | TGCTCCTGGACTGTTCG | 395 |
GCTTCACTCCTGTGGGT | |||
3 | Survivin | AGGTGCCTGTTGAATCTG | 318 |
GACGCTTCCTATCACTCTATT | |||
4 | IL-2 | AAGACCCAGGGACTT | 280 |
GGTTGCTGTCTCATCA | |||
5 | Granulysin | CTGCGTGATGAGGAGAAA | 400 |
GGGTCGCAGCATT | |||
6 | FAK | TCCACCAAAGAAACCG | 500 |
TCTGTGCCATCTCAATCT | |||
7 | IL-1 | CGCCTGACAGAAACCA | 300 |
GCGAATGACAGAGGGT | |||
8 | IL-8 | CAGCCTTCCTGATTTC | 300 |
AACCCTCTGCACCCA | |||
9 | Cox-1 | ATCCAGAAACAGTGGCTCG | 248 |
CAACCAATGGCGTG | |||
10 | C-myc | ACGCCGCTCGGAAGGAAT | 300 |
TCCACCGTGACCACATCG | |||
11 | VEGF | CCCACCCACATACATACA | 230 |
CCTCCCAACTCAAGTCC | |||
12 | Stufen | GCTGCGAAACACGATGCT | 300 |
CTGGGCCAGTCGGCTAAT | |||
13 | C10orf46 | TTTGGCTCCGCTTTCTCG | 550 |
CTCCCAGTTGTTGTGGTTCT | |||
14 | Ki-67 | TTGCCTCCTAATACGC | 280 |
CTTCCGAAGCACCACT | |||
15 | Granulysin | CTGCGTGATGAGGAGAAA | 320 |
GGGTCGCAGCATT | |||
16 | top2B | GACAATGCCCTCACC | 500 |
CCAGGCTCCTTCTTC | |||
17 | MTHFR | ACCGCCGTGAACTACTGT | 350 |
GCCTCCCTCCTCCTCTT | |||
18 | PCNA | CAAGGACCTCATCAACG | 400 |
ACTTTCTCCTGGTTTGG | |||
19 | P15 | TGGACCTGGTGGCTACGAAT | 200 |
肿瘤种类 | 统计数量(例) | 隐血实验阳性 | 芯片检测阳性 |
咽喉相关肿瘤 | 3 | 0 | 0 |
食管癌 | 5 | 0 | 1 |
贲门癌 | 1 | 0 | 0 |
胃间质癌肝转 | 1 | 0 | 0 |
原发性肝癌 | 1 | 0 | 0 |
种类 | 统计数量(例) | 隐血实验阳性 | 芯片检测阳性 |
正常人群1(低危人群) | 20 | 0 | 0 |
正常人群2(高危人群) | 28 | 2 | 1 |
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CN2007101957941A CN101624616B (zh) | 2007-12-17 | 2007-12-17 | 用于检测大肠癌的基因组合及其基因芯片 |
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CN101624616A CN101624616A (zh) | 2010-01-13 |
CN101624616B true CN101624616B (zh) | 2012-01-04 |
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CN102747155A (zh) * | 2012-07-09 | 2012-10-24 | 南京大学 | 毒理基因组学指数预警饮用水源水致癌风险的方法 |
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Denomination of invention: Novel gene combination for detecting colorectal cancer and gene chip thereof Effective date of registration: 20150428 Granted publication date: 20120104 Pledgee: Bank of China, Limited by Share Ltd, Lanzhou hi tech Zone subbranch Pledgor: Lanzhou Baiyuan Gene Technology Co., Ltd. Registration number: 2015990000331 |
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