CN101618128B - Medicine for treating hemorrhoid and preparation method thereof - Google Patents
Medicine for treating hemorrhoid and preparation method thereof Download PDFInfo
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- CN101618128B CN101618128B CN2009100751404A CN200910075140A CN101618128B CN 101618128 B CN101618128 B CN 101618128B CN 2009100751404 A CN2009100751404 A CN 2009100751404A CN 200910075140 A CN200910075140 A CN 200910075140A CN 101618128 B CN101618128 B CN 101618128B
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Abstract
The invention relates to a medicine for treating hemorrhoid. A preparation method of the medicine comprises the following steps: mixing and grinding angelica, red phaseolus beans and burned sanguisorba into powder; grinding sanguis draconis and borneol into powder; adding the powder into medical powder to evenly mix; and capsuling the powder to prepare the medicine for treating hemorrhoids. The medicine for treating hemorrhoid has the effects of fever reduction, detoxification, blood circulation promotion, blood stasis removal, necrosis removal, granulation promotion, astringency, hemostasis, detumescence and pain alleviation, is used for treating the diseases of defecation bleeding, crissum pain, and the like of hemorrhoids, is especially suitable for damp-heat pouring downward internal hemorrhoid and has determined curative effect, no toxic side effect, and the like. The clinical efficacy observation of 60 patients shows that the total effective rate can reach 98.3 percent.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of hemorrhoids disease, particularly relating to a kind of is the medicine of the treatment hemorrhoid of feedstock production with Chinese medicine.The invention still further relates to the preparation method of this medicine.
Background technology
Hemorrhoid are up and down agglomerates of causing of venous plexus cirso-of tooth trace both sides rectum, and produce hemorrhage, thromboembolism thus or agglomerate is deviate from, and have another name called hemorrhoid, blood stasis, hemorrhoid disease, haemorrhoids etc.According to the difference at position, hemorrhoid place, be divided into three types of internal hemorrhoid, external hemorrhoid and mixed hemorrhoids again.Hemorrhoid are human distinctive commonly encountered diseases, frequently-occurring disease, show according to relevant reconnaissance information, and the sickness rate of anorectal disease is 59.1%, and hemorrhoid account for 87.25% of all anal and intestinal diseases, and are wherein common with internal hemorrhoid again, account for 52.19% of all anal and intestinal diseases.The hemorrhoid majority is in static, asymptomatic state.Once because of long-time defecation, sitting standing for a long time and the pungent irritable food of surfeit or other bring out, increase the weight of the factor of hemorrhoid, when symptom such as defecation is hemorrhage, the hemorrhoid piece is deviate from, pain occurring, then need active treatment.Even treat successfully, also easily recurrence.Therefore hemorrhoid belong to a kind of refractory disease clinically.
Though the western medical treatment hemorrhoid adopt medicine oral administration and externally, injection treatment, cryotherapy, operative therapy etc. often at present, first of treatment hemorrhoid select to remain the employing non-operative treatment.The emphasis of its treatment is to eliminate symptom, rather than hemorrhoid itself, and short of tangible symptom and sign can be treated, and the symptom is arranged, and symptom and sign disappear can reach therapeutic purposes.These Therapeutic Method just alleviate or make transference cure, local organization is restored to the original state as far as possible or the pathological change disappearance, anal orifice and rectal intestine lower end, anal canal, konstantinovich's vein clump are no longer deposited, crooked, varicose becomes the vein agglomerate but can not make, and therefore are easy to cause the hemorrhoid recurrence.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of hemorrhoid, this medicine has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, and removing the necrotic tissue and promoting granulation, astringing to arrest bleeding, the reducing swelling and alleviating pain effect, treatment hemorrhoid effect is remarkable, and relapse rate is low.
A kind of manufacturing method for above mentioned medicine is provided, and is another goal of the invention of the present invention.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Sanguis Draxonis 1～5 Radix Angelicae Sinensis 10～30
Semen Phaseoli 20～60 burnt Radix Sanguisorbaes 10～30
Borneolum Syntheticum 0.3～3
Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is a capsule.
The concrete preparation method of above-mentioned each component being made capsule of the present invention is:
According to above-mentioned parts by weight, get Radix Angelicae Sinensis, Semen Phaseoli, burnt Radix Sanguisorbae mixing after, it is standby to be ground into 100～120 purpose fine powders; Be ground into 100～120 fine powder after getting Sanguis Draxonis, Borneolum Syntheticum mix homogeneously, with said medicine fine powder mix homogeneously, in incapsulating, sterilization makes the capsule product.
Motherland's medical science think hemorrhoid be damp and hot due to, damp-heat in the large intestine should at will be discharged, and is not smooth as discharging, and accumulates with the passing of time, anal orifice and rectal intestine is done harm to by it, then generates hemorrhoid.Control suitable heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis, reducing swelling and alleviating pain.In the prescription of the present invention, burnt Radix Sanguisorbae bitter in the mouth, acid, cold nature, the energy cooling blood for hemostasis, skin ulcer is held back in detoxifcation, is principal agent in the side, is apt to control the inferior burnt heat in blood and has blood in stool; Ministerial drug Semen Phaseoli sweet in the mouth, acid, property is flat, and property is kind descending, the energy clearing away heat-damp and promoting diuresis, the promoting the circulation of blood detumescence, tonneau urine makes damp and hot heresy go out from urine; Radix Angelicae Sinensis sweet in the mouth, suffering, warm in nature, the energy blood-supplementing blood-nourishing, promoting blood circulation and stopping pain, Sanguis Draxonis sweet in the mouth, salty, property is flat, the analgesic therapy of invigorating blood circulation, hemostasia and promoting granulation is apt to control stagnation of blood stasis and is had a pain, and skin infection does not close up for a long time, and Borneolum Syntheticum heat-clearing and toxic substances removing, reducing swelling and alleviating pain, three medicines are adjuvant drug altogether.Full monarch's side one minister one, assistant three, all medicine compatibilities are played heat-clearing and toxic substances removing altogether, blood circulation promoting and blood stasis dispelling, removing the necrotic tissue and promoting granulation, astringing to arrest bleeding, the merit of reducing swelling and alleviating pain, diseases such as the hemorrhoid stool is hemorrhage in order to treat, crissum pain are adapted to the damp heat downward flowing type internal hemorrhoid especially.
For further investigating the clinical efficacy and the safety of medicine of the present invention, select 60 routine hemorrhoid patients that the curative effect of Drug therapy hemorrhoid of the present invention has been carried out clinical observation.
60 routine patients are the out-patient, wherein male 21 examples, women 39 examples, 42.7 years old mean age.
Diagnostic criteria: I phase internal hemorrhoid: have blood in stool, color is scarlet, or asymptomatic, and the anus microscopy is seen tooth trace top mucosal protrusion, and surplus color is light red.II phase internal hemorrhoid: have blood in stool, color is scarlet, deviates from anus with swollen thing, after an action of the bowels can be from horizontal reset, and the anus microscopy is seen tooth trace top mucosal protrusion, surplus color is dark red.
Chinese medical discrimination standard: damp heat downward flowing type: the hemorrhoid surplus color is scarlet or livid purple, and it is hemorrhage to rub during often because of stool, a line such as arrow when hemorrhage, or drop is endlessly, the hemorrhoid piece is not deviate from outside the anus, or deviates from outside the anus just the time, and very fast after an action of the bowels answer has persistence to have an intense pain, red tongue, yellow fur, wiry and frequent pulse.
Therapeutic Method: oral medicine of the present invention, 3 times on the one, each 3.2 weeks were 1 course of treatment, evaluated curative effect after 2 courses of treatment.
Criterion of therapeutical effect:
Recovery from illness: clinical symptom disappearance, check and see that the hemorrhoid piece disappears;
Produce effects: clinical symptom disappearance, check and see that the hemorrhoid piece obviously dwindles;
Effectively: clinical symptoms is improved, and checks that seeing that the hemorrhoid piece has dwindles;
Invalid: hemorrhoid piece no change is seen in clinical symptoms and inspection.
60 routine patients are after treatment, and 56 examples of fully recovering account for 93.3%, and produce effects 2 examples account for 3.3%; Effective 1 example accounts for 1.7%; Invalid 1 example accounts for 1.7%.Total effective rate is 98.3%.
The specific embodiment
Embodiment 1
Get Sanguis Draxonis 50g, Radix Angelicae Sinensis 300g, Semen Phaseoli 600g choose most impurity, clean screening, dry the back mix homogeneously, and it is standby to be ground into 120 order fine powders.
With burnt Radix Sanguisorbae 300g, Borneolum Syntheticum 30g is ground into 100 purpose fine powders, and with above-mentioned medicated powder mixing, in incapsulating, sterilization makes the capsule product.
Embodiment 2
Get Sanguis Draxonis 50g, Radix Angelicae Sinensis 1000g, Semen Phaseoli 1000g choose most impurity, clean screening, dry the back mix homogeneously, and it is standby to be ground into 120 order fine powders.
With burnt Radix Sanguisorbae 750g, Borneolum Syntheticum 25g is ground into 100 purpose fine powders, and with above-mentioned medicated powder mixing, in incapsulating, sterilization makes the capsule product.
Embodiment 3
Get Sanguis Draxonis 25g, Radix Angelicae Sinensis 150g, Semen Phaseoli 300g choose most impurity, clean screening, dry the back mix homogeneously, and it is standby to be ground into 120 order fine powders.
With burnt Radix Sanguisorbae 150g, Borneolum Syntheticum 15g is ground into 100 purpose fine powders, and with above-mentioned medicated powder mixing, in incapsulating, sterilization makes the capsule product.
Embodiment 4
Get Sanguis Draxonis 75g, Radix Angelicae Sinensis 500g, Semen Phaseoli 600g choose most impurity, clean screening, dry the back mix homogeneously, and it is standby to be ground into 120 order fine powders.
With burnt Radix Sanguisorbae 450g, Borneolum Syntheticum 45g is ground into 100 purpose fine powders, and with above-mentioned medicated powder mixing, in incapsulating, sterilization makes the capsule product.
Claims (3)
1. medicine for the treatment of the damp heat downward flowing type internal hemorrhoid is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Sanguis Draxonis 1～5 Radix Angelicae Sinensis 10～30
Semen Phaseoli 20～60 burnt Radix Sanguisorbaes 10～30
Borneolum Syntheticum 0.3～3.
2. the medicine of treatment damp heat downward flowing type internal hemorrhoid according to claim 1 is characterized in that described medicine is made capsule.
3. the preparation method of the medicine of the described treatment damp heat downward flowing type of claim 2 internal hemorrhoid is according to above-mentioned parts by weight, get Radix Angelicae Sinensis, Semen Phaseoli, burnt Radix Sanguisorbae mixing after, it is standby to be ground into 100～120 purpose fine powders; Be ground into 100～120 purpose fine powders after getting Sanguis Draxonis, Borneolum Syntheticum mix homogeneously, with said medicine fine powder mix homogeneously, sterilization makes the capsule product in incapsulating.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009100751404A CN101618128B (en) | 2009-08-12 | 2009-08-12 | Medicine for treating hemorrhoid and preparation method thereof |
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| CN2009100751404A CN101618128B (en) | 2009-08-12 | 2009-08-12 | Medicine for treating hemorrhoid and preparation method thereof |
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| CN101618128A CN101618128A (en) | 2010-01-06 |
| CN101618128B true CN101618128B (en) | 2011-06-22 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105233209A (en) * | 2015-10-24 | 2016-01-13 | 孙桂芝 | Suppository for treating hemorrhoids with syndrome of downward flow of damp heat |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1442167A (en) * | 2003-04-12 | 2003-09-17 | 程祥荣 | Making method of capsule for treating hemorrhoid |
| CN1589860A (en) * | 2003-08-27 | 2005-03-09 | 陈帮映 | Chinese medicinal composition for treating hemorrhoid |
| CN101455771A (en) * | 2008-12-25 | 2009-06-17 | 赵建良 | External traditional Chinese medicine ointment for treating hemorrhoid |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1442167A (en) * | 2003-04-12 | 2003-09-17 | 程祥荣 | Making method of capsule for treating hemorrhoid |
| CN1589860A (en) * | 2003-08-27 | 2005-03-09 | 陈帮映 | Chinese medicinal composition for treating hemorrhoid |
| CN101455771A (en) * | 2008-12-25 | 2009-06-17 | 赵建良 | External traditional Chinese medicine ointment for treating hemorrhoid |
Non-Patent Citations (2)
| Title |
|---|
| 田静.辨证治疗内痔出血28例.《实用中医药杂志》.2005,第21卷(第12期),724-725. * |
| 魏照洲.从瘀论治痔疮.《四川中医》.2006,第24卷(第11期),76-77. * |
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Granted publication date: 20110622 Termination date: 20120812 |