CN101617966A - After-cornea refractive surgery artificial lens design - Google Patents

After-cornea refractive surgery artificial lens design Download PDF

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Publication number
CN101617966A
CN101617966A CN200810053731A CN200810053731A CN101617966A CN 101617966 A CN101617966 A CN 101617966A CN 200810053731 A CN200810053731 A CN 200810053731A CN 200810053731 A CN200810053731 A CN 200810053731A CN 101617966 A CN101617966 A CN 101617966A
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refractive surgery
cornea
eye
cornea refractive
eye model
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CN200810053731A
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Chinese (zh)
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王肇圻
饶丰
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Nankai University
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Nankai University
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Abstract

The invention belongs to the technical field of vision correction and cataract vision therapy. A before-refractive surgery individualized eye model is built by using ZEMAX optical design software according to a corneal topography, an axial distance between components in an eye and a wavefront aberration which are obtained before the cornea refractive surgery; an after-refractive surgery individualized eye model is built by combining an wavefront aberration actually measured after the cornea refractive surgery; and, finally, a bispherical artificial lens for correcting defocusing and a spherical column-shaped artificial lens for correcting a defocusing and astigmation are designed by using the model.

Description

The lenticular design of after-cornea refractive surgery artificial
Technical field
The invention belongs to vision correcting and cataract therapy technical field.
Background technology
Since eighties of last century since the eighties, cornea refractive surgery is accepted by people gradually, and worldwide carries out widely.With age, cataract has much taken place in the human eye of (abbreviation postoperative) behind the first generation cornea refractive surgery.At present, be used for clinically calculating the postoperative intraocular lens (Intraocular Lens, IOL) method of the number of degrees mainly contains:
(1) the clinical medical history method of Holladay J T proposition, (before being called for short art) diopter of cornea deducted the diopter of operation change before promptly the corneal diopter of postoperative equaled cornea refractive surgery, calculated the number of degrees of IOL then with classical formulas.
(2) the IOL number of degrees are adjusted method, comprise that Feiz-Mannis adjusts method and Masket adjusts method, the former utilizes the corneal diopter before the art to calculate the needed IOL number of degrees, the diopter that changes with cornea refractive surgery obtains the number of degrees adjusted value that IOL needs divided by 0.7 then, and the two subtracts each other and has promptly obtained the needed IOL number of degrees of postoperative; The latter thinks that the number of degrees that the number of degrees that IOL adjusts and cornea refractive surgery remove are linear, and for axis oculi greater than 23mm, adopt the Holladay-I formula, less than 23mm, the number of degrees of IOL after the employing Hoffer-Q formula logistic.
(3) people such as Walter K A has proposed cornea the method for bypass, and the target refractive status that the number of degrees that cornea refractive surgery is removed are reserved as postcataract calculates the number of degrees of IOL with classical formulas.
(4) the Pntacam direct method of measurement is directly measured the diopter of post-operative cornea central area, and the substitution classical formulas is calculated.
The IOL diopter calculates classical formulas:
IOL = 1336 AL - ELP - 1336 1336 1000 1000 Dpost - V + K - ELP
Wherein, AL represents axiallength, and ELP represents artificial intraocular lenses's active position, it is the distance that corneal vertex arrives intraocular lens's front principal plane, K represents corneal diopter, and V represents the distance that the perioperatively corneal vertex moves, and Dpost represents the corneal vertex diopter behind the cornea refractive surgery.
Although method is numerous, find that the number of degrees that calculate are inaccurate (error can reach 5D) in clinical, cause occurring behind the cataract operation ametropia in various degree.In addition, present method also can't astigmatism.
Summary of the invention
The purpose of this patent is that with human eyes wave-front optical aberration, cornea refractive surgery cornea topographic map data and ophthalmic each several part axial spacing data before and after the cornea refractive surgery of actual measurement be fundamental construction postoperative personalized eye model.In this eye model, add the intraocular lens then,, design intraocular lens's structure of individual human eye, improve the visual quality of human eye by the optimizational function of optical design software Zemax.
This invention has following function and advantage:
Function one, wavefront aberration data, cornea characteristic parameter and ophthalmic each several part axial spacing data before the cornea refractive surgery of known actual human eye, utilization optical design software Zemax makes up the personalized eye model before the cornea refractive surgery, then in conjunction with the wave front aberration behind the cornea refractive surgery, make up personalized eye model behind the cornea refractive surgery.
Function two adds two sphere intraocular lenss, optimizes intraocular lens's front and rear surfaces curvature behind the cornea refractive surgery that makes up in the personalized eye model, reaches the rectification burnt purpose of having hallucinations entirely.
Function three adds the goalpost intraocular lens, optimizes intraocular lens's front and rear surfaces curvature and astigmatic angle behind the cornea refractive surgery that makes up in the personalized eye model, reaches and corrects have hallucinations entirely burnt and scattered-light purpose simultaneously.
Concrete technical scheme
The technical scheme of this invention comprises following main aspect:
One is accurately measured the cornea front and rear surfaces shape of individual human eye by the medical cornea activity mapping instrument, carries out the shape match with the high order aspheric surface function and is placed in the eye model; Measure the axial width of each several parts such as human eye's anterior chamber, crystalline lens, vitreous body with medical A-mode ultrasonic wave technology, these thickness as in the optical interval input eye model; Lenticular surface configuration is optimized, makes the wave front aberration of the actual measurement that wave front aberration and the cornea refractive surgery of full eye is preceding equate.
Its two, corneal front surface face type is optimized, and makes that the wave front aberration of actual measurement equates behind wave front aberration and the cornea refractive surgery of full eye.
Its three, behind cornea refractive surgery, add two sphere intraocular lenss in the personalized eye model, optimize its face structure, correct the out of focus of full eye.
Its four, behind cornea refractive surgery, add the goalpost intraocular lens in the personalized eye model, optimize its curvature and astigmatic angle, correct the out of focus and the astigmatism of full eye.
Description of drawings
Accompanying drawing 1 is the flow chart of the lenticular design of after-cornea refractive surgery artificial of the present invention.
Specify embodiments of the present invention below in conjunction with accompanying drawing 1.
Concrete embodiment
As shown in Figure 1, corneal topographer Orbscan II[1] be used for measuring cornea front and rear surfaces curvature and with respect to the height value of reference sphere.Anterior corneal surface is converted into difference in height along optical axis direction along the difference in height of radius vector direction, simulates the non-spherical surface [2] of cornea with the high order aspheric surface function.
BMF-200A type audigage [3] is used for measuring each component axial spacing of axis oculi, comprises corneal thickness, anterior chamber depth, lens thickness and vitreous body thickness [4].
Wavescan II wavefront analyzer [5] is used for measuring the wave front aberration [6] of human eye, the aberration data of individual human eye is added in the majorized function of optical design software Zemax, defines the actual aberration of human eye with this.
The ophthalmic optical system comprises cornea, aqueous humor, crystalline lens and Vitrea medium refraction index and Abbe number [7] The data Gullstrand le-grand eye model numerical value.
The face type of crystalline lens [8] is set to Ze Nike rise face, optimizes lenticular front and rear surfaces parameter, makes the wave front aberration of full eye equate with the wave front aberration that obtains with actual measurement.The preceding personalized eye model [9] of operation on cornea this moment has made up to be finished.
Measure the wave front aberration [11] of human eye behind the cornea refractive surgery with Wavescan II wavefront analyzer [5], and it is added in the majorized function of optical design software Zemax, define the actual aberration of human eye behind the cornea refractive surgery with this.Anterior surface of cornea is defined as variable,, makes the wave front aberration of full eye equate with the preceding aberration of the operation postwave of actual measurement by optimizing.Personalized human-eye model [10] has made up and has finished behind this moment operation on cornea.
Intraocular lens [12] is placed on the position of ophthalmic cataract operation requirement, optimizes its face structure to correct out of focus [13] or out of focus and astigmatism [14].

Claims (3)

1. the structure of personalized eye model behind the cornea refractive surgery.It is characterized in that: the wave front aberration by personalized eye model behind the refractive surgery full aberration that gets and the actual human eye that measures with wavefront analyzer equates, posterior surface of cornea changes before and after crystalline lens and the axis oculi refractive surgery and disregards.
2. based on two sphere intraocular lenss' of personalized eye model behind the cornea refractive surgery design, it is characterized in that: the out of focus that can correct full eye by Zemax software to the optimization of intraocular lens's structure.
3. based on the goalpost intraocular lens's of personalized eye model behind the cornea refractive surgery design, it is characterized in that: out of focus and the astigmatism that can correct full eye by Zemax software to the optimization of intraocular lens's structure.
CN200810053731A 2008-07-02 2008-07-02 After-cornea refractive surgery artificial lens design Pending CN101617966A (en)

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Application Number Priority Date Filing Date Title
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397117A (en) * 2010-09-07 2012-04-04 郑泽钧 Artificial lens, manufacturing method for artificial lens and method for treating cataract by using artificial lens
CN102551654A (en) * 2012-01-20 2012-07-11 王毅 Optical coherence biological measurer and method for biologically measuring eyes
CN106901873A (en) * 2017-03-09 2017-06-30 首都医科大学附属北京同仁医院 The preparation method of intraocular lens
CN112957004A (en) * 2021-02-01 2021-06-15 复旦大学附属眼耳鼻喉科医院 IOLMASter image-based crystalline lens curvature and diopter acquisition method and system
CN114587775A (en) * 2020-12-04 2022-06-07 艾维斯技术有限责任公司 Customized ablation for correcting vision ametropia
CN114748242A (en) * 2022-04-13 2022-07-15 南开大学 Cornea ablation design method and device for wavefront-guided refractive surgery

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397117A (en) * 2010-09-07 2012-04-04 郑泽钧 Artificial lens, manufacturing method for artificial lens and method for treating cataract by using artificial lens
CN102397117B (en) * 2010-09-07 2014-03-12 郑泽钧 Artificial lens, manufacturing method for artificial lens and method for treating cataract by using artificial lens
CN102551654A (en) * 2012-01-20 2012-07-11 王毅 Optical coherence biological measurer and method for biologically measuring eyes
CN102551654B (en) * 2012-01-20 2013-09-18 王毅 Optical coherence biological measurer and method for biologically measuring eyes
CN106901873A (en) * 2017-03-09 2017-06-30 首都医科大学附属北京同仁医院 The preparation method of intraocular lens
CN114587775A (en) * 2020-12-04 2022-06-07 艾维斯技术有限责任公司 Customized ablation for correcting vision ametropia
CN112957004A (en) * 2021-02-01 2021-06-15 复旦大学附属眼耳鼻喉科医院 IOLMASter image-based crystalline lens curvature and diopter acquisition method and system
CN112957004B (en) * 2021-02-01 2023-12-19 复旦大学附属眼耳鼻喉科医院 Lens curvature and diopter acquisition method and system based on IOLMaster image
CN114748242A (en) * 2022-04-13 2022-07-15 南开大学 Cornea ablation design method and device for wavefront-guided refractive surgery
CN114748242B (en) * 2022-04-13 2023-01-10 南开大学 Corneal ablation design method and device for wavefront-guided refractive surgery

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Open date: 20100106