CN102397117A - Artificial lens, manufacturing method for artificial lens and method for treating cataract by using artificial lens - Google Patents

Artificial lens, manufacturing method for artificial lens and method for treating cataract by using artificial lens Download PDF

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CN102397117A
CN102397117A CN2010102779178A CN201010277917A CN102397117A CN 102397117 A CN102397117 A CN 102397117A CN 2010102779178 A CN2010102779178 A CN 2010102779178A CN 201010277917 A CN201010277917 A CN 201010277917A CN 102397117 A CN102397117 A CN 102397117A
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cornea
diopter
corneal
curvature
analyst coverage
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CN102397117B (en
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郑泽钧
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Abstract

The invention provides a method for manufacturing an artificial lens. The method comprises the following steps of: measuring the front surface curvature of the cornea of an eye in a first analysis range, and measuring the back surface curvature of the cornea in a second analysis range, wherein the first analysis range and the second analysis range have a same center point; measuring the thickness of the cornea at the center point; calculating the diopter of the cornea through an equation; measuring an axis oculi; calculating an effective lens position from the back surface curvature of the cornea; calculating the dioper of the artificial lens according to the dioper of the cornea, the axis oculi and the effective lens position; and manufacturing the artificial lens according to the dioper of the artificial lens. The invention also provides the artificial lens manufactured by the method. The invention also provides a method for treating cataract by using the artificial lens.

Description

Artificial intraocular lenses and manufacturing approach thereof and use artificial intraocular lenses treat cataractous method
Technical field
The present invention relates to a kind of artificial intraocular lenses and manufacturing approach thereof, relate to a kind of artificial intraocular lenses and manufacturing approach of making according to the radian of anterior surface of cornea and posterior surface of cornea thereof especially.
Background technology
Before patient was carried out cataract operation, the doctor must calculate artificial intraocular lenses's radian and the position of putting earlier.Wherein, artificial intraocular lenses's radian is to be calculated by the radian of patient's eyes cornea.Traditional method only is to use an estimative figure to calculate the radian of cornea., accepted the strong philtrum of looking of refractive surgery such as laser once, it is inaccurate that this estimative figure can become.
Summary of the invention
The technical problem that the present invention will solve is, rectifys the philtrum of looking once accepting refractive surgery such as laser, and the calculating of existing computational methods corneal curvature is inaccurate.
For solving the problems of the technologies described above, the present invention provides a kind of manufacture of intraocular crystalline method on the one hand, may further comprise the steps:
Measure eye's cornea front surface curvature in first analyst coverage,
Surface curvature after second analyst coverage is measured eye's cornea, this first analyst coverage and second analyst coverage have same central point,
Measure the thickness of cornea at said central point,
Calculate corneal diopter through following equality:
K = P 1 + P 2 - d n 1 P 1 P 2
Wherein, K is a corneal diopter; P1 is the anterior surface of cornea diopter, and promptly P2 is the posterior surface of cornea diopter, i.e. the corneal thickness of
Figure BSA00000265154900013
d for using ultrasonic corneal pachymeter to measure; N0 is the dioptric coefficient of air; N1 is the dioptric coefficient of cornea, and n2 is the dioptric coefficient of aqueous humor, and r1 is an anterior surface of cornea curvature; R2 is a posterior surface of cornea curvature
Measure axis oculi,
Calculate effective crystal position from said posterior surface of cornea curvature,
According to said corneal diopter, axis oculi and the effective said artificial intraocular lenses's of crystal position calculation diopter and
Make said artificial intraocular lenses with said diopter.
In one embodiment of the invention, said first analyst coverage is the circle of 3 millimeters of diameters.
In one embodiment of the invention, said second analyst coverage is that overall diameter is 10 millimeters, and interior diameter is 7 millimeters a annulus.
In one embodiment of the invention, said central point is the central point of pupil.
Another aspect of the present invention is a kind of artificial intraocular lenses who processes according to said method, and said artificial intraocular lenses's diopter is according to corneal diopter, and axis oculi comes out with effective crystal position calculation, wherein:
Corneal diopter is according to the anterior surface of cornea curvature of measuring out in first analyst coverage, and posterior surface of cornea curvature of measuring out in second analyst coverage and the corneal thickness that uses ultrasonic corneal pachymeter to measure out calculate through following equality:
K = P 1 + P 2 - d n 1 P 1 P 2
Wherein, K is a corneal diopter; P1 is the anterior surface of cornea diopter, and promptly
Figure BSA00000265154900022
P2 is the posterior surface of cornea diopter, i.e. the corneal thickness of
Figure BSA00000265154900023
d for using ultrasonic corneal pachymeter to measure; N0 is the dioptric coefficient of air; N1 is the dioptric coefficient of cornea, and n2 is the dioptric coefficient of aqueous humor, and r1 is an anterior surface of cornea curvature; R2 be posterior surface of cornea curvature and
Effectively calculate through said posterior surface of cornea curvature the crystal position.
Another aspect of the present invention be a kind of use artificial intraocular lenses to treat cataractous method, may further comprise the steps:
Measure eye's cornea front surface curvature in first analyst coverage,
Surface curvature after second analyst coverage is measured cornea, this first analyst coverage and second analyst coverage have same central point,
Measure the thickness of cornea at said central point,
Calculate corneal diopter through following equality:
K = P 1 + P 2 - d n 1 P 1 P 2
Wherein, K is a corneal diopter; P1 is the anterior surface of cornea diopter, and promptly
Figure BSA00000265154900032
P2 is the posterior surface of cornea diopter, i.e. the corneal thickness of
Figure BSA00000265154900033
d for using ultrasonic corneal pachymeter to measure; N0 is the dioptric coefficient of air; N1 is the dioptric coefficient of cornea, and n2 is the dioptric coefficient of aqueous humor, and r1 is an anterior surface of cornea curvature; R2 is a posterior surface of cornea curvature
Measure axis oculi,
Calculate effective crystal position from said posterior surface of cornea curvature,
According to said corneal diopter, axis oculi and effective said artificial intraocular lenses's of crystal position calculation diopter,
Make said artificial intraocular lenses with said diopter,
Extract cataract patient crystal and
Said artificial intraocular lenses is implanted in said effective crystal position of patient's ophthalmic.
The invention has the beneficial effects as follows: rectified and to look operation no matter whether patient carries out refractive surgery such as laser in the past; Can calculate artificial intraocular lenses's radian and the position of putting exactly, thereby lower the probability that causes the artificial intraocular lenses to implant the permanent hypermetropia of appearance behind the cataract patient because of artificial intraocular lenses's diopter mistake.The contrast prior art, the present invention once carried out the cataract patient of cornea refractive surgery to those, and was more accurate in the calculating of corneal diopter and effective crystal position.
Wherein, curvature and thickness that utilization of the present invention is measured out by instrument calculate the diopter of anterior surface of cornea and posterior surface of cornea respectively, and the required adjustment of making of distance between two surfaces, thereby can calculate corneal diopter more accurately.The posterior surface of cornea curvature of using the cornea periphery scope that performs an analysis to measure also can be estimated more accurately that refractive surgery such as laser are rectified and look preoperative corneal diopter, to calculate effective crystal position more accurately.
Description of drawings
Remaining part and accompanying drawing with reference to this description can be done further to understand to performance of the present invention and advantage; The label of same assembly is identical in these accompanying drawings.In some cases, sub-labelling is placed in certain label and hyphen back to represent one of them of many similar assemblies.When mentioning certain label but when not writing some existing sub-labellings especially exactly, just be meant all these similar assemblies.
Fig. 1 a is the simplification cross-sectional view of normal human subject eyes.
To be human eyes rectify and look perioperative simplification cross-sectional view carrying out laser Fig. 1 b.The variation of postoperative anterior surface of cornea is represented by dotted lines.
Fig. 2 is according to one embodiment of the invention, the flow chart of the crystalline method of a kind of manufacture of intraocular.
Fig. 3 is according to one embodiment of the invention, a kind of flow chart that obtains the method for corneal diopter.
Fig. 4 a is the front view of anterior surface of cornea, shows the strong relation that looking the scope of operation influence of first analyst coverage and laser.
Fig. 4 b is the front view of posterior surface of cornea, shows the strong relation that looking the scope of operation influence of second analyst coverage and laser.
Fig. 5 a is for to use Orbscan to measure the view of cornea surface curvature as central point with corneal vertex.
Fig. 5 b is for to use Orbscan to measure the view of cornea surface curvature as central point with pupil center.
The specific embodiment
With reference to Fig. 1 a, this figure is the simplification cross-sectional view of human eyes 20 earlier.Cornea 30 is the most external of eyes 20.In cornea 30 outsides is air 28, and is aqueous humor 32 between cornea 30 and the crystal 26.Light is from outer entering, and the dioptric through cornea 30 and crystal 26 focuses on the retina 31 at last.
Existing with reference to Fig. 1 b, this figure has shown that eyes are carrying out the for example strong front and back contrast of looking operation of myopia property laser of cornea refractive surgery.Cornea 30 has anterior surface of cornea 22 and posterior surface of cornea 24.Before carrying out refractive surgery, anterior surface of cornea 22 is approximately spherical with posterior surface of cornea.Partly in operation, can be cut or polished in the middle of the anterior surface of cornea 22, thereby become flat, formed the new anterior surface of cornea 34 in operation back.
Fig. 2 has shown the flow chart of a manufacture of intraocular crystal method.This method comprises acquisition corneal diopter (step 36); Measure axis oculi (step 38) and calculate effective crystal position (step 40); And according to above-mentioned diopter; Axis oculi and effective said artificial intraocular lenses's of crystal position calculation diopter (step 42) is made said artificial intraocular lenses (step 44) with this diopter again.
Can learn from the flow chart of Fig. 2; Want the manufacture of intraocular crystal will know corneal diopter earlier; And in traditional corneal curvature appearance; The diopter of the cornea that calculates for
Figure BSA00000265154900051
wherein r be the curvature of the anterior surface of cornea measuring out, and n is a single dioptric coefficient 1.3375 of being fabricated according to the eye model of Gullstrand.The curvature that behind one of them of this numeral is assumed to be anterior surface of cornea 22 and posterior surface of cornea 24 becomes a fixed ratio (6.8: 7.7), so anterior surface of cornea is taken as single surperficial calculating with posterior surface of cornea in this model.Rectify when looking operation carrying out myopia property laser, because the curvature of anterior surface of cornea 34 reduces and cornea partly thickness attenuation in the centre, above-mentioned hypothesis is no longer set up, so error can appear in the corneal diopter that uses above-mentioned imaginary numerical calculation to come out.
Fig. 3 is for removing to obtain the flow chart of the method for corneal diopter (step 36) according to one embodiment of the invention.This method at first first analyst coverage measure eye's cornea front surface curvature and after second analyst coverage is measured cornea surface curvature (step 46), this first analyst coverage and second analyst coverage have same central point.Measure the thickness (step 48) of cornea then at said central point, i.e. distance between anterior surface of cornea and the posterior surface of cornea.After obtaining these parameters, this method is calculated corneal diopter (step 50) through following equality:
K = P 1 + P 2 - d n 1 P 1 P 2 [equality (1)]
Wherein, K is a corneal diopter; P1 is the anterior surface of cornea diopter; Promptly
Figure BSA00000265154900062
P2 is the posterior surface of cornea diopter; Promptly
Figure BSA00000265154900063
d is the corneal thickness that uses ultrasonic corneal pachymeter to measure; N0 is the dioptric coefficient (1.0) of air, and n1 is the dioptric coefficient (1.376) of cornea, and n2 is the dioptric coefficient (1.336) of aqueous humor; R1 is anterior surface of cornea curvature (millimeter), and r2 is posterior surface of cornea curvature (millimeter).
Using said method to calculate corneal diopter compared with only using the numerical calculation of fabricating to come more accurately, is a fixed ratio because this method is not supposed anterior surface of cornea curvature and posterior surface of cornea curvature by error.Said method uses the curvature r1 that measures out; R2 and thickness d, elder generation calculates the diopter P1 of anterior surface of cornea and posterior surface of cornea, P2 respectively; And the required adjustment of making of distance between two surfaces, corneal diopter just can calculate from equality (1) exactly.
The selection of analyst coverage can produce great influence to the accuracy of said method.Because the curvature of measuring out in different analyst coverages has difference.In one embodiment of the invention, first analyst coverage is the circle 52 of 3 millimeters of diameters shown in Fig. 4 a.The reason of selecting 3 millimeters is that all carry out laser and rectify the patient's look operation anterior surface of cornea and all can in this scope, become flat.If 3 millimeters of diameter serious offenses, when particularly being bigger than 5 millimeters, the edge of scope possibly break away from laser and rectify the scope (with broken circle 54 expressions) of looking the operation influence.This can cause the curvature of scope center and peripheral different, and causes that error appears in the result who draws at last.In another embodiment, the diameter of first analyst coverage be 5 millimeters or below.
Compared with anterior surface of cornea, measuring of posterior surface of cornea curvature more is prone to error, and reason is that corneal curvature appearance such as Orbscan II must just can measure the data of posterior surface of cornea earlier through the refraction of anterior surface of cornea.There is document to be logged into Orbscan II and once carries out the inaccuracy that laser is rectified the posterior surface of cornea curvature look surgical patient measuring.Laser is rectified and is looked curvature and the thickness that operation can change the middle part of anterior surface of cornea, thereby the posterior surface of cornea ratio of curvature practical situation that order is measured out is high.
In one embodiment of the invention, second analyst coverage is the circle of 10 millimeters of diameters.These 10 millimeters is the size of about whole cornea, and because the relation that the deviation measured mainly partly takes place in the centre, and the error of therefore measuring whole cornea and being drawn is low compared with the data of only using mid portion to draw.In another embodiment of the present invention, show that like Fig. 4 b second analyst coverage is the periphery of cornea.Surround circularly outward, the diameter of the cylindrical 58 of annulus 56 is the same 10 millimeters of the face of catching up with, and the diameter of interior circle 60 is 7 millimeters.Rectify at myopia property laser and to look in the operation less because anterior surface of cornea is rectified the influence of looking operation in this scope Stimulated Light, so the hypothesis of cornea front and rear surfaces curvature ratio still come into force, thereby improve the accuracy of calculating.It is intermediary about 5-6 millimeter basically that laser is rectified the scope look the operation influence, and the circle of 5 millimeters of diameters is with broken circle 54 expressions.Basically only using the peripheral data that draw is accurately compared with using whole cornea.Some corneal curvature appearance such as Orbscan II can freely select analyst coverage, therefore can only use peripheral measuring.If other corneal curvature appearance can not be accomplished this point, then need use whole cornea scope so that error is reduced to minimum.
The calculating of tradition corneal curvature is all with optical center, or the summit 62 of cornea is a central point.Fig. 5 a is for to use Orbscan to remove to measure the view of one of them surface power of cornea as central point with corneal vertex., light must could arrive retina through pupil earlier, and the center of pupil might not be overlapping with the summit of cornea.If use the central point of the summit of cornea as analyst coverage, the curvature of measuring out possibly not be best suited for patient's.As shown in Fig. 5 a, white point is represented pupil center, and white circle is for being the circle in the center of circle with the pupil center.Visible white circle has departed from concentric black circle from figure, promptly is the circle in the center of circle with the corneal vertex.Therefore, the curvature of measuring out from black circle is not optimal to patient.
In one embodiment of the invention, shown in Fig. 5 b, the central point of first and second analyst coverage is made as the central point of pupil.Because all are measured is the center with the pupil all, do not depart from the wrong and correction that corneal vertex causes so do not need to comprehend again pupil, and the result who draws is best suited for patient's.It is the function of analyst coverage central point that some corneal curvature appearance such as Orbscan II have the selection pupil.
Mention as above, calculate artificial intraocular lenses's diopter,, also will measure axis oculi and calculate effective crystal position except obtaining corneal diopter.Axis oculi can be measured for example A-mode ultrasonic ripple scanning etc. through known method.Effectively the calculating of crystal position can be calculated through the double-K method.Two K here are respectively and do refractive surgery such as strong corneal diopter and the postoperative corneal diopter looked preoperative of laser.If before operation, have no the data of corneal diopter, just need to estimate that this diopter is to make to calculate purposes.
In one embodiment of the invention, preoperative corneal diopter is estimated from postoperative posterior surface of cornea diopter.The method uses above-mentioned method to remove to measure the diopter of posterior surface of cornea as analyst coverage with the periphery earlier.Because of known posterior surface of cornea the place ahead is that the cornea tissue rear is an aqueous humor; And know their dioptric coefficient; The diopter of posterior surface of cornea just can use
Figure BSA00000265154900081
to be calculated; N1 wherein, the definition of n2 and r2 is with above the same.Value is multiplied by the diopter that a constant just can be learnt anterior surface of cornea more thus, and substitution equality (1) just can draw preoperative corneal diopter again.To rectify the influence of looking operation minimum because of the peripheral Stimulated Light of posterior surface of cornea, the corneal diopter that more than the calculates corneal diopter of can estimating more accurately to perform the operation.
Postoperative corneal diopter can obtain according to the described method of Fig. 3 or other method.After learning these two numerical value, effectively the crystal position can be calculated through the double-K method.
Obtaining corneal diopter, behind axis oculi and the effective crystal position, artificial intraocular lenses's diopter can use known method to calculate, and for example Holladay 1, and Holladay 2, Haigis, SRK/T, Hoffer Q method etc.
Another aspect of the present invention is a kind of artificial intraocular lenses, and artificial intraocular lenses's diopter is according to corneal diopter, and axis oculi comes out with effective crystal position calculation.The anterior surface of cornea curvature of corneal diopter from measuring out in first analyst coverage; The posterior surface of cornea curvature of measuring out in second analyst coverage; With the corneal thickness that uses ultrasonic corneal pachymeter to measure out, calculate corneal diopter through above-mentioned equality (1).Effectively calculate through said posterior surface of cornea curvature the crystal position.
In a preferred embodiment, said corneal diopter obtains through Fig. 2 and method shown in Figure 3.
Another aspect of the present invention is that a kind of use artificial intraocular lenses is to treat cataractous method.This method elder generation obtains corneal diopter, measure axis oculi and calculate effective crystal position, and according to above-mentioned diopter, axis oculi and effective said artificial intraocular lenses's of crystal position calculation diopter is made said artificial intraocular lenses with this diopter again.The method that obtains said corneal diopter be at first first analyst coverage measure eye's cornea front surface curvature and after second analyst coverage is measured cornea surface curvature, this first analyst coverage and second analyst coverage have same center.Measure the thickness of cornea then at said center, i.e. distance between anterior surface of cornea and the posterior surface of cornea.After obtaining these parameters, this method is calculated corneal diopter through above-mentioned equality (1).Effectively calculate through said posterior surface of cornea curvature the crystal position.
Made after the artificial intraocular lenses, this method also comprises the crystal of extracing cataract patient, then said artificial intraocular lenses is implanted in said effective crystal position.
Above content is to combine concrete embodiment to the further explain that the present invention did, and can not assert that practical implementation of the present invention is confined to these explanations.For the those of ordinary skill of technical field under the present invention, under the prerequisite that does not break away from the present invention's design, can also make some simple deduction or replace, all should be regarded as belonging to protection scope of the present invention.

Claims (12)

1. the crystalline method of manufacture of intraocular is characterized in that, may further comprise the steps:
Measure eye's cornea front surface curvature in first analyst coverage,
Surface curvature after second analyst coverage is measured eye's cornea, this first analyst coverage and second analyst coverage have same central point,
Measure the thickness of cornea at said central point,
Calculate corneal diopter through following equality:
K = P 1 + P 2 - d n 1 P 1 P 2
Wherein, K is a corneal diopter; P1 is the anterior surface of cornea diopter; Promptly
Figure FSA00000265154800012
P2 is the posterior surface of cornea diopter; Promptly
Figure FSA00000265154800013
d is the corneal thickness that uses ultrasonic corneal pachymeter to measure, and n0 is the dioptric coefficient of air, and n1 is the dioptric coefficient of cornea; N2 is the dioptric coefficient of aqueous humor; R1 is an anterior surface of cornea curvature, and r2 is a posterior surface of cornea curvature
Measure axis oculi,
Calculate effective crystal position from said posterior surface of cornea curvature,
According to said corneal diopter, axis oculi and the effective said artificial intraocular lenses's of crystal position calculation diopter and
Make said artificial intraocular lenses with said diopter.
2. the method for claim 1 is characterized in that, said first analyst coverage is the circle of 3 millimeters of diameters.
3. the method for claim 1 is characterized in that, said second analyst coverage is the circle of 10 millimeters of diameters.
4. the method for claim 1 is characterized in that, said second analyst coverage is that overall diameter is 10 millimeters, and interior diameter is 7 millimeters a annulus.
5. the method for claim 1 is characterized in that, said central point is the central point of pupil.
6. artificial intraocular lenses who makes like each method among the claim 1-5, said artificial intraocular lenses's diopter is according to corneal diopter, and axis oculi comes out with effective crystal position calculation, wherein:
Corneal diopter is according to the anterior surface of cornea curvature of measuring out in first analyst coverage, and posterior surface of cornea curvature of measuring out in second analyst coverage and the corneal thickness that uses ultrasonic corneal pachymeter to measure out calculate through following equality:
K = P 1 + P 2 - d n 1 P 1 P 2
Wherein, K is a corneal diopter; P1 is the anterior surface of cornea diopter; Promptly
Figure FSA00000265154800022
P2 is the posterior surface of cornea diopter; Promptly
Figure FSA00000265154800023
d is the corneal thickness that uses ultrasonic corneal pachymeter to measure, and n0 is the dioptric coefficient of air, and n1 is the dioptric coefficient of cornea; N2 is the dioptric coefficient of aqueous humor; R1 is an anterior surface of cornea curvature, r2 be posterior surface of cornea curvature and
Effectively calculate through said posterior surface of cornea curvature the crystal position.
7. one kind is used the artificial intraocular lenses to treat cataractous method, it is characterized in that, may further comprise the steps:
Measure eye's cornea front surface curvature in first analyst coverage,
Surface curvature after second analyst coverage is measured cornea, this first analyst coverage and second analyst coverage have same central point,
Measure the thickness of cornea at said central point,
Calculate corneal diopter through following equality:
Figure FSA00000265154800024
Wherein, P1 is the anterior surface of cornea diopter; Promptly
Figure FSA00000265154800025
P2 is the posterior surface of cornea diopter; Promptly
Figure FSA00000265154800026
d is the corneal thickness that uses ultrasonic corneal pachymeter to measure, and n0 is the dioptric coefficient of air, and n1 is the dioptric coefficient of cornea; N2 is the dioptric coefficient of aqueous humor; R1 is an anterior surface of cornea curvature, and r2 is a posterior surface of cornea curvature
Measure axis oculi,
Calculate effective crystal position from said posterior surface of cornea curvature,
According to said corneal diopter, axis oculi and effective said artificial intraocular lenses's of crystal position calculation diopter,
Make said artificial intraocular lenses with said diopter,
Extract cataract patient crystal and
Said artificial intraocular lenses is implanted in said effective crystal position of patient's ophthalmic.
8. purposes as claimed in claim 7 is characterized in that, said first analyst coverage is the circle of 3 millimeters of diameters.
9. purposes as claimed in claim 7 is characterized in that, said second analyst coverage is the circle of 10 millimeters of diameters.
10. purposes as claimed in claim 7 is characterized in that, said second analyst coverage is that overall diameter is 10 millimeters, and interior diameter is 7 millimeters a annulus.
11. purposes as claimed in claim 7 is characterized in that, said central point is the central point of pupil.
12. a dioptric method of calculating the artificial intraocular lenses is characterized in that, may further comprise the steps:
Measure eye's cornea front surface curvature in first analyst coverage,
Surface curvature after second analyst coverage is measured eye's cornea, this first analyst coverage and second analyst coverage have same central point,
Measure the thickness of cornea at said central point,
Calculate corneal diopter through following equality:
K = P 1 + P 2 - d n 1 P 1 P 2
Wherein, K is a corneal diopter; P1 is the anterior surface of cornea diopter; Promptly
Figure FSA00000265154800032
P2 is the posterior surface of cornea diopter; Promptly
Figure FSA00000265154800033
d is the corneal thickness that uses ultrasonic corneal pachymeter to measure, and n0 is the dioptric coefficient of air, and n1 is the dioptric coefficient of cornea; N2 is the dioptric coefficient of aqueous humor; R1 is an anterior surface of cornea curvature, and r2 is a posterior surface of cornea curvature
Measure axis oculi,
From said posterior surface of cornea curvature calculate effective crystal position and
According to said corneal diopter, axis oculi and effective said artificial intraocular lenses's of crystal position calculation diopter.
CN201010277917.8A 2010-09-07 2010-09-07 Artificial lens, manufacturing method for artificial lens and method for treating cataract by using artificial lens Expired - Fee Related CN102397117B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106901873A (en) * 2017-03-09 2017-06-30 首都医科大学附属北京同仁医院 The preparation method of intraocular lens

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US20030033013A1 (en) * 1997-08-20 2003-02-13 Callahan Wayne B. Method of using a small incision lens
US6811256B1 (en) * 2000-12-08 2004-11-02 Paul Douglas Becherer Post-ophthalmologic procedure lenses and methods
CN1553783A (en) * 2001-09-10 2004-12-08 ʿ Intraocular lens derivation system
CN101617966A (en) * 2008-07-02 2010-01-06 南开大学 After-cornea refractive surgery artificial lens design

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030033013A1 (en) * 1997-08-20 2003-02-13 Callahan Wayne B. Method of using a small incision lens
US6811256B1 (en) * 2000-12-08 2004-11-02 Paul Douglas Becherer Post-ophthalmologic procedure lenses and methods
CN1553783A (en) * 2001-09-10 2004-12-08 ʿ Intraocular lens derivation system
CN101617966A (en) * 2008-07-02 2010-01-06 南开大学 After-cornea refractive surgery artificial lens design

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106901873A (en) * 2017-03-09 2017-06-30 首都医科大学附属北京同仁医院 The preparation method of intraocular lens

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