CN1951340A - Artificial crystal design based on personalized human's eye model - Google Patents
Artificial crystal design based on personalized human's eye model Download PDFInfo
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- CN1951340A CN1951340A CN 200510015419 CN200510015419A CN1951340A CN 1951340 A CN1951340 A CN 1951340A CN 200510015419 CN200510015419 CN 200510015419 CN 200510015419 A CN200510015419 A CN 200510015419A CN 1951340 A CN1951340 A CN 1951340A
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Abstract
The invention is based on personal eye mode, with crystal eye (PIOL) structure to improve the view function. Wherein, it uses the tested eye wave-front aberration, cornea character parameter and axial distances of eye elements to build the eye mode; then arranges artificial crystal into the mode, to correct the eye aberration; and uses zemax software to guide in aspheric surface. The invention can predict the aberration accurately, and evaluate the eccentric condition of PIOL on the view function.
Description
Technical field
The invention belongs to the vision correcting technical field.
Background technology
The ametropia of correcting human eye is the research focus of ophthalmology in recent years.Laser in Situ Keratomileusis (LASIK) is applicable to the rectification low myopia, and for high myopia, because the cornea tissue of cutting is too much, the cornea loss of stability, the predictability of lasik surgery reduces greatly, and tangible visual disorder is arranged under the half-light.Crystal eye artificial intraocular lenses is arranged, and (Phakic Intraocular lens, PIOL) implanting advantages such as the method for correcting high myopia is few with its post-operative complication, effect stability more and more is that people pay close attention to.
Van der Heijde formula medically commonly used at present calculates the diopter of PIOL:
S.E.=R
d+ R
a/ 2 formula 3
In the formula 1, K is a corneal curvature, and unit is D;
ELP is effective artificial intraocular lenses's position, and promptly anterior chamber depth deducts the distance between PIOL and the iris, and unit is m.
R
cFor the artificial intraocular lenses at the planar diopter of corneal vertex, unit is D;
In the formula 2, V is the mirror point distance when measuring the human eye diopter, and value is 0.012m usually;
S.E is the equivalent diopter of sphere;
In the formula 3, R
dAnd R
aBe respectively the out of focus and astigmatism that are got by optometry before the art, unit is D;
Bring the cross curvature and the longitudinal curvature of cornea into theoretical formula 1 respectively, calculate the diopter of PIOL at both direction, both differences are the astigmatism diopter of required PIOL.Laterally diopter is the out of focus diopter of required PIOL.This formula is not considered the wavefront aberration data of actual human eye in the calculating of out of focus and astigmatism, thereby defectiveness.
Because of the particularity of opthalmic optics system, spherical aberration is the most obvious to the influence that PIOL inserts back human eye image quality.At present less for the trial of correcting the human eye spherical aberration with aspheric artificial intraocular lenses, only limit to draw the meansigma methods of the cornea spherical aberration on the statistical significance by the cornea shape data that measure, the spherical aberration of PIOL is introduced negative value compensate with it, thereby can't accurately correct according to the actual optical characteristics of individual human eye.
Summary of the invention
The purpose of this patent is that human eyes wave-front optical aberration, cornea characteristic parameter and the ophthalmic each several part axial spacing data with actual measurement are the fundamental construction lens structure, thereby further make up personalized human-eye model, in this human-eye model, insert PIOL, optimizational function by Zemax software, design the structure of individual human eye PIOL, improve the visual function of human eye.
This invention has following function and advantage:
Function one, the wavefront aberration data of known actual human eye, cornea characteristic parameter and ophthalmic each several part axial spacing data, utilization optical design software Zemax makes up personalized human-eye model.
Function two, known PIOL position within the eye, the structure of optimization PIOL reaches the purpose of correcting human eye out of focus and astigmatism in the human-eye model that makes up.
Function three, because of the particularity of opthalmic optics system, spherical aberration is the most obvious to the influence that PIOL inserts back human eye image quality.Based on personalized human-eye model, utilize the optimizational function of Zemax software, introduce non-spherical structure, overcome the influence of spherical aberration to the human eye visual function.
Function four, after analyzing the artificial intraocular lenses and insert with personalized human-eye model, the off-centre that produces in individual human eye is to the influence of human eye visual function.Produce rotation displacement that eccentric possible factor comprises PIOL, along the axial displacement of human eye, longitudinally displacement and PIOL face shape mismachining tolerance etc.
Concrete technical scheme
The technical scheme of this invention comprises following main aspect:
One is accurately measured the cornea front and rear surfaces shape of individual human eye by the medical cornea activity mapping instrument, carries out the shape match with the high order aspheric surface function and is placed in the eye model; Measure the axial width of each several parts such as human eye's anterior chamber, crystalline lens, vitreous body with medical A-mode ultrasonic wave technology, these thickness are imported in the eye model as optical interval; Lenticular surface configuration is optimized, makes the wave aberration of full eye equate with the actual wave aberration that personnel selection glances wavefront aberrometer measures.
Its two, between cornea and iris, insert PIOL, optimize the face structure of PIOL, correct the out of focus and the astigmatism of full eye.
Its three, based on the human-eye model that makes up, in Zemax, introduce secondary aspherical, optimize the PIOL structure with the rectification spherical aberration.
Its four, on the basis of personalized human-eye model, the eccentric influence that the human eye visual function is produced is analyzed in simulation PIOL displacement within the eye.
Description of drawings
Accompanying drawing 1 is the artificial intraocular lenses's design flow diagram that the present invention is based on personalized eye model.
Accompanying drawing 2 is the present invention's human-eye model structural representations after inserting PIOL.
Specify embodiments of the present invention below in conjunction with accompanying drawing.
Concrete embodiment
As shown in Figure 1, Hartmann-Shack Wavefront sensor [1] is used for measuring the wave front aberration of human eye, the aberration data of individual human eye is joined in the majorized function of optical design software Zemax, defines the actual aberration of human eye with this.
Corneal topographer Orbscan II[2] be used for measuring corneal curvature and cornea front and rear surfaces height value with respect to the reference sphere.Anterior corneal surface is converted into vertically difference in height along the difference in height of radius vector direction, simulates the non-spherical surface of cornea with the high order aspheric surface function.
A-mode ultrasonic calibrator [3] is used for measuring the each several part spacing of axis oculi, comprises cornea front and rear surfaces spacing, the camera oculi anterior degree of depth, lens thickness and Vitrea thickness.
The ophthalmic optical system comprises cornea, aqueous humor, crystalline lens and Vitrea medium refraction index [4] The data Gullstrand eye model numerical value.
The face type of crystalline lens [5] is set to Ze Nike rise face, optimizes lenticular front and rear surfaces, makes the wave aberration of full eye equate with the actual wave aberration that personnel selection glances wavefront aberrometer measures.Personalized human-eye model [6] made up and finished this moment.
With PIOL[7] place between cornea and the iris, optimize its face structure, promptly obtain inserting the human-eye model [8] behind the PIOL.
As shown in Figure 2, the personalized human-eye model that has made up comprises anterior surface of cornea [1], posterior surface of cornea [2], crystalline lens front surface [5], crystalline lens rear surface [6] and retina [7].
The front surface of PIOL [3] is set to super ring curved surface and sphere respectively with rear surface [4], optimizes the front and rear surfaces of PIOL, corrects the out of focus and the astigmatism of human eye.
Introduce aspheric surface on the basis of personalized PIOL design, the spherical aberration of human eye is set to zero in the majorized function, corrects spherical aberration by the optimizational function of Zemax.
On the basis of personalized PIOL design, introduce certain offset, analyze the influence of PIOL off-centre displacement within the eye, comprise modulation transfer function (MTF) and point spread function (PSF) etc. the human eye visual function.
Claims (4)
1. the artificial intraocular lenses's design based on personalized human-eye model comprises cornea, built-in artificial intraocular lenses (PIOL), crystalline lens and amphiblestroid structure.It is characterized in that: the wave front aberration by personalized human-eye model full aberration that gets and the actual human eye that measures with wavefront analyzer equates.
2. require described artificial intraocular lenses's design according to right 1 based on personalized human-eye model, it is characterized in that: can correct the out of focus and the astigmatism of human eye by Zemax to the optimization of PIOL structure, the optimization of PIOL structure has comprised the individual lenticular feature based on wavefront aberration data.
3. require described artificial intraocular lenses's design according to right 1, it is characterized in that: introduce aspheric surface and optimize the spherical aberration that the PIOL structure can be corrected human eye based on personalized human-eye model.
4. require described artificial intraocular lenses's design according to right 1, it is characterized in that: in personalized human-eye model, introduce certain offset, can analyze the influence of PIOL off-centre displacement within the eye the human eye visual function based on personalized human-eye model.
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| CN100589780C (en) * | 2007-12-28 | 2010-02-17 | 中国科学院光电技术研究所 | Reflection type artificial crystal optical aberration hartmann measuring apparatus |
| CN101199437B (en) * | 2006-05-17 | 2010-12-08 | 爱尔康制造有限公司 | Correction of higher order aberratons in intraocular lenses |
| CN101957502A (en) * | 2010-08-31 | 2011-01-26 | 吉林大学 | Design method of individualized cornea contact lens |
| CN101972135A (en) * | 2010-11-02 | 2011-02-16 | 吉林大学 | Detection method of individual lenticular surface shape data |
| CN102467612A (en) * | 2010-11-18 | 2012-05-23 | 沈阳理工大学 | Method for constructing individual eye optical model |
| US9335563B2 (en) | 2012-08-31 | 2016-05-10 | Amo Groningen B.V. | Multi-ring lens, systems and methods for extended depth of focus |
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| CN100589780C (en) * | 2007-12-28 | 2010-02-17 | 中国科学院光电技术研究所 | Reflection type artificial crystal optical aberration hartmann measuring apparatus |
| US10197815B2 (en) | 2008-05-13 | 2019-02-05 | Amo Groningen B.V. | Multi-ring lens, systems and methods for extended depth of focus |
| CN101957502A (en) * | 2010-08-31 | 2011-01-26 | 吉林大学 | Design method of individualized cornea contact lens |
| CN101972135A (en) * | 2010-11-02 | 2011-02-16 | 吉林大学 | Detection method of individual lenticular surface shape data |
| CN102467612A (en) * | 2010-11-18 | 2012-05-23 | 沈阳理工大学 | Method for constructing individual eye optical model |
| US10136805B2 (en) | 2010-12-15 | 2018-11-27 | Amo Groningen B.V. | Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration |
| US10456026B2 (en) | 2010-12-15 | 2019-10-29 | Amo Wavefront Sciences, Llc | Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration |
| US9335563B2 (en) | 2012-08-31 | 2016-05-10 | Amo Groningen B.V. | Multi-ring lens, systems and methods for extended depth of focus |
| US11022815B2 (en) | 2012-08-31 | 2021-06-01 | Amo Groningen B.V. | Multi-ring lens, systems and methods for extended depth of focus |
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| WO2017180914A1 (en) * | 2016-04-13 | 2017-10-19 | Amo Wavefront Sciences, Llc | Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration |
| CN106420110A (en) * | 2016-08-24 | 2017-02-22 | 滕植鑫 | Pediatric intraocular lens degree prediction method |
| CN110087585A (en) * | 2016-09-29 | 2019-08-02 | 司斐股份有限公司 | Lens for astigmatism |
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| US11523897B2 (en) | 2017-06-23 | 2022-12-13 | Amo Groningen B.V. | Intraocular lenses for presbyopia treatment |
| US11262598B2 (en) | 2017-06-28 | 2022-03-01 | Amo Groningen, B.V. | Diffractive lenses and related intraocular lenses for presbyopia treatment |
| US11156853B2 (en) | 2017-06-28 | 2021-10-26 | Amo Groningen B.V. | Extended range and related intraocular lenses for presbyopia treatment |
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| US11327210B2 (en) | 2017-06-30 | 2022-05-10 | Amo Groningen B.V. | Non-repeating echelettes and related intraocular lenses for presbyopia treatment |
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| CN116071522A (en) * | 2023-02-24 | 2023-05-05 | 首都医科大学宣武医院 | Method for establishing individual artificial lens model eye |
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