CN112957004A - IOLMASter image-based crystalline lens curvature and diopter acquisition method and system - Google Patents
IOLMASter image-based crystalline lens curvature and diopter acquisition method and system Download PDFInfo
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- CN112957004A CN112957004A CN202110136724.9A CN202110136724A CN112957004A CN 112957004 A CN112957004 A CN 112957004A CN 202110136724 A CN202110136724 A CN 202110136724A CN 112957004 A CN112957004 A CN 112957004A
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- 238000000034 method Methods 0.000 title claims abstract description 26
- 210000000695 crystalline len Anatomy 0.000 title description 150
- 210000004087 cornea Anatomy 0.000 claims abstract description 22
- 210000001742 aqueous humor Anatomy 0.000 claims description 6
- 210000004127 vitreous body Anatomy 0.000 claims description 6
- 238000004364 calculation method Methods 0.000 claims description 2
- 238000000691 measurement method Methods 0.000 claims 4
- 230000000877 morphologic effect Effects 0.000 claims 1
- 238000011160 research Methods 0.000 abstract description 3
- 238000005259 measurement Methods 0.000 description 5
- 210000001508 eye Anatomy 0.000 description 4
- 210000005252 bulbus oculi Anatomy 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 208000002177 Cataract Diseases 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 210000002159 anterior chamber Anatomy 0.000 description 1
- 230000004323 axial length Effects 0.000 description 1
- 230000001886 ciliary effect Effects 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000004379 myopia Effects 0.000 description 1
- 208000001491 myopia Diseases 0.000 description 1
- 230000004423 myopia development Effects 0.000 description 1
- 238000012014 optical coherence tomography Methods 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/1005—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring distances inside the eye, e.g. thickness of the cornea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/103—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/107—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining the shape or measuring the curvature of the cornea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/117—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
- A61B3/1173—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes for examining the eye lens
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Abstract
本发明涉及一种基于IOLMaster图像的晶状体曲率和屈光度获取方法与系统，所述系统用于执行如下方法：获取角膜前表面曲率半径与晶状体厚度值、对应的晶状体形态图片；获取角膜前表面像素、晶状体前表面像素、晶状体后表面像素；输出晶状体前表面曲率半径值及晶状体后表面曲率半径值，其中，所述角膜前表面曲率半径与晶状体前表面曲率半径值之比等于角膜前表面像素与晶状体前表面像素之比、所述角膜前表面曲率半径与晶状体后表面曲率半径之比等于角膜前表面像素与晶状体后表面像素之比；输出晶状体前、后表面屈光力、晶状体总屈光力；其能基于IOLMaster图像直观获取晶状体参数，极大的提升了相应研究的高效性。
The invention relates to a method and system for acquiring lens curvature and diopter based on an IOLMaster image. The system is used to execute the following methods: acquiring the corneal anterior surface curvature radius and lens thickness values, and corresponding lens morphology pictures; acquiring corneal anterior surface pixels, Lens anterior surface pixel, lens posterior surface pixel; output lens anterior surface curvature radius value and lens posterior surface curvature radius value, wherein, the ratio of the corneal anterior surface curvature radius to the lens anterior surface curvature radius value is equal to the corneal anterior surface surface pixel and the lens The ratio of anterior surface pixels, the ratio of the radius of curvature of the anterior surface of the cornea to the radius of curvature of the posterior surface of the lens is equal to the ratio of the pixels of the anterior surface of the cornea to the pixels of the posterior surface of the lens; output the refractive power of the anterior and posterior surfaces of the lens, and the total refractive power of the lens; it can be based on IOLMaster The lens parameters can be obtained intuitively from the image, which greatly improves the efficiency of the corresponding research.
Description
Technical Field
The present invention relates to a method and system for lens parameter calculation based on IOLMmaster images and a computer program product configured to implement the method.
Background
The lens is a biconvex transparent tissue, is fixedly suspended behind the iris in front of the vitreous body, is one of important refraction interstitials in the eyeball, and has the most important function of changing the diopter through contraction or relaxation of ciliary muscles, so that the focusing point of the eyeball can be accurately positioned on the retina when the eyeball looks far or near. The change of diopter is valuable for analyzing the refractive change and development trend of eyes, and particularly in the development of myopia, the influence of the change of the lens shape on the myopia is a worthy subject to be researched. However, no instrument can directly measure the change of the radian and the diopter of the crystalline lens at present, so the method for measuring, calculating and measuring the radian and the diopter of the crystalline lens is sought by utilizing the existing detection technology and combining the computer operation technology and the optical principle.
The IOLMASTER eye biological measuring instrument is an optical biological measuring instrument using non-contact technology, and accurately measures the axial length of the eye, the corneal curvature and the anterior chamber depth of a patient; the problem of accurately measuring the biological parameters of the eyes and accurately predicting the intraocular lens (IOL) to be implanted before cataract operation is innovatively solved, and the device is a high-precision instrument; IOLMASTER 700 is based on the measurement principle of optical coherence tomography, has a central wavelength of 1055mm, can scan from 6 angles, and can clearly display the parameters of the shape curve and thickness of the anterior and posterior surfaces of the cornea, the shape curve and thickness of the anterior and posterior surfaces of the crystalline lens, and the like; IOLMASTER 700 can image a full lens and has been able to directly measure values related to the curvature of the cornea and lens thickness, but has not been able to obtain the radius of curvature of the anterior and posterior surfaces of the lens; measurement of the curvature of the anterior and posterior surfaces of the lens is currently a challenge.
In view of the foregoing, there is a need for a method of acquiring lens curvature and diopter that enables intuitive acquisition of lens parameters based on IOLMmaster images.
Disclosure of Invention
The invention aims to provide a lens curvature and diopter acquisition method capable of visually acquiring lens parameters based on IOLMASter images.
In order to achieve the purpose, the invention adopts the technical scheme that:
a lens curvature and diopter acquisition method based on an IOLMaster image, comprising: acquiring the curvature radius of the front surface of the cornea, the thickness value of the crystalline lens and a corresponding crystalline lens shape picture; acquiring cornea front surface pixels, lens front surface pixels and lens rear surface pixels, wherein the lens front surface pixels, the lens rear surface pixels and the cornea front surface pixels are obtained by analyzing a lens form picture;
outputting a lens anterior surface radius of curvature value and a lens posterior surface radius of curvature value, wherein a ratio of the corneal anterior surface radius of curvature to the lens anterior surface radius of curvature value is equal to a ratio of corneal anterior surface pixels to lens anterior surface pixels and a ratio of corneal anterior surface radius of curvature to lens posterior surface radius of curvature is equal to a ratio of corneal anterior surface pixels to lens posterior surface pixels; outputting an anterior lens surface power and a posterior lens surface power; the total refractive power of the lens is output.
As a preferred technical solution, the value of the curvature radius of the anterior surface of the cornea and the thickness of the crystalline lens is measured by IOLMaster 700; the lens morphology picture is generated by IOLMaster 700.
As a preferable technical scheme, the lens morphology picture is analyzed by matlab to obtain corneal anterior surface pixels, lens anterior surface pixels and lens posterior surface pixels.
As a preferable technical scheme, the refractive power of the front surface of the lens is obtained by calculating the refractive index of the aqueous humor, the refractive index of the lens, the refractive index of the vitreous body, the curvature radius of the front surface of the lens and the curvature radius of the rear surface of the lens: anterior lens surface power: fa ═ (n 2-n 1)/Ca; lens posterior surface refractive power: fb ═ (n 3-n 2)/Cp; wherein the refractive index of the aqueous humor is n1, the refractive index of the lens is n2, the refractive index of the vitreous body is n3, and the value of the radius of curvature of the anterior surface of the lens, Ca, and the value of the radius of curvature of the posterior surface of the lens, Cp, are both in meters.
As a preferable technical scheme, the total refractive power of the lens is obtained by calculating the front surface refractive power of the lens, the back surface refractive power of the lens, the thickness of the lens and the refractive index of the lens: total refractive power of lens: ft is Fa + Fb-LT × Fa × Fb/n 2; wherein the lens thickness is LT in meters.
It is another object of the present invention to provide a lens curvature and diopter acquisition system capable of visually acquiring lens parameters based on IOLMMaster images.
In order to achieve the purpose, the invention adopts the technical scheme that:
a lens curvature and diopter acquisition system based on an IOLMaster image comprising: an acquisition module: the device is used for acquiring the curvature radius of the front surface of the cornea, the thickness value of the crystalline lens, a corresponding crystalline lens shape picture and parameter information of pixels of the front surface of the cornea, pixels of the front surface of the crystalline lens and pixels of the rear surface of the crystalline lens; an output module: the lens front surface refractive power, the lens back surface refractive power and the total refractive power of the lens are output; the IOLMASTER image-based lens curvature and diopter acquisition system executes the IOLMASTER image-based lens curvature and diopter acquisition method of any one of claims 1 to 5.
The invention also provides a storage medium which comprises a stored program, wherein when the program runs, the equipment on which the storage medium is arranged is controlled to execute the IOLMmaster image-based lens curvature and diopter acquisition method.
The invention also provides a processor for running a program, wherein the program runs to execute the IOLMmaster image-based lens curvature and diopter acquisition method.
The invention has the advantages that:
the method and the system for obtaining the lens curvature and the diopter based on the IOLMMaster image realize the application of intuitively obtaining the lens parameters based on the IOLMMaster image, can directly feed back the measurement result of the lens, directly output the curvature radius value of the front surface of the lens and the curvature radius value of the rear surface of the lens, and further directly output the front surface refractive power of the lens, the rear surface refractive power of the lens and the total refractive power of the lens.
Drawings
FIG. 1 is a flow chart of a method for obtaining lens curvature and diopter based on IOLMmaster image.
FIG. 2 is a block diagram of a lens curvature and diopter acquisition system based on an IOLMmaster image according to the present invention.
Detailed Description
The invention will be further illustrated with reference to specific embodiments. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that various changes and modifications can be made by those skilled in the art after reading the disclosure of the present invention, and equivalents fall within the scope of the appended claims.
The reference numerals and components referred to in the drawings are as follows:
22. acquisition module 24 output module
Example 1
Referring to fig. 1, fig. 1 is a flow chart of a method for obtaining curvature and diopter of a lens based on an IOLMaster image according to the present invention. A method for obtaining lens curvature and diopter based on IOLMaster images, the method at least comprising the steps of:
step S100: acquiring the curvature radius of the front surface of the cornea, the thickness value of the crystalline lens and a corresponding crystalline lens shape picture;
in some embodiments of the present application, the anterior corneal surface radius of curvature and lens thickness values are measured by IOLMASTER 700; a lens morphology picture is also generated by iolmmaster 700;
step S102: acquiring cornea front surface pixels, lens front surface pixels and lens rear surface pixels, wherein the lens front surface pixels, the lens rear surface pixels and the cornea front surface pixels are obtained by analyzing a lens form picture;
in some embodiments of the present application, the lens morphology picture is imported into matlab software, and the matlab software is used for analyzing to obtain corneal anterior surface pixels, lens anterior surface pixels and lens posterior surface pixels respectively;
step S104: outputting a lens anterior surface radius of curvature value and a lens posterior surface radius of curvature value, wherein a ratio of the corneal anterior surface radius of curvature to the lens anterior surface radius of curvature value is equal to a ratio of corneal anterior surface pixels to lens anterior surface pixels and a ratio of corneal anterior surface radius of curvature to lens posterior surface radius of curvature is equal to a ratio of corneal anterior surface pixels to lens posterior surface pixels;
step S106: outputting an anterior lens surface power and a posterior lens surface power;
in some embodiments of the present application, the refractive powers of the anterior and posterior surfaces of the lens are obtained by matlab software based on the aqueous refractive index, lens refractive index, vitreous refractive index, and anterior and posterior lens surface radii of curvature:
anterior lens surface power: fa ═ (n 2-n 1)/Ca;
lens posterior surface refractive power: fb ═ (n 3-n 2)/Cp;
wherein the refractive index of the aqueous humor is n1, the refractive index of the crystalline lens is n2, the refractive index of the vitreous body is n3, and the front surface curvature radius value Ca and the rear surface curvature radius value Cp of the crystalline lens are both in meters;
step S108: outputting a total refractive power of the lens;
in some embodiments of the present application, the anterior lens surface power, the posterior lens surface power, the lens thickness, the lens refractive index are input and obtained by matlab software:
total refractive power of lens: ft + Fa + Fb-LT x Fa x Fb/n2
Wherein the lens thickness is LT in meters.
It should be noted that: according to the IOLMmaster image-based crystalline lens curvature and diopter obtaining method, the front surface curvature radius value Ca and the rear surface curvature radius value Cp of the crystalline lens are obtained through pixel comparison, so that the front surface curvature radius value Ca and the rear surface curvature radius value Cp of the crystalline lens can be directly obtained by using the IOLMmaster image, rapidness, high efficiency and high correspondence are achieved, the front surface refractive power and the rear surface refractive power of the crystalline lens and the total refractive power of the crystalline lens can be directly obtained, the direct measurement of the crystalline lens form and diopter is achieved, and the research on the crystalline lens and the related application research are enhanced.
Referring to fig. 2, fig. 2 is a block diagram of a lens curvature and diopter acquisition system based on an IOLMaster image according to the present invention. A lens curvature and diopter acquisition system based on an IOLMaster image comprising:
the acquisition module 22: the device is used for acquiring parameter information of the curvature radius of the front surface of the cornea, the thickness value of the crystalline lens, a corresponding crystalline lens shape picture, pixels of the front surface of the cornea, pixels of the front surface of the crystalline lens and pixels of the rear surface of the crystalline lens;
the output module 24: the lens front surface refractive power, the lens back surface refractive power and the total refractive power of the lens are output; the IOLMASTER image-based lens curvature and diopter acquisition system can execute the IOLMASTER image-based lens curvature and diopter acquisition method, and can realize direct reading of the lens measurement result by an instrument.
It should be noted that: the protection scope of the present invention also includes a processor executing the IOLMmaster image-based lens curvature and diopter acquisition method, an operation program thereof, and a storage medium storing the operation program thereof.
Example 2
The present embodiment will be described with reference to specific data:
obtaining a measured lens shape picture through an IOLMmaster 700, and obtaining a measured cornea front surface curvature radius of 7.80mm and a pixel of 252; while the anterior lens surface pixel is 410 and the posterior lens surface pixel is 240; according to the pixel comparison: the cornea anterior surface radius of curvature/lens anterior surface radius of curvature is 252/410, and the value of the lens anterior surface radius of curvature Ca is obtained: 12.69 mm; the anterior corneal surface radius of curvature/posterior lens surface radius of curvature is 252/240, and the value of posterior lens surface radius of curvature Cp is obtained: 7.43 mm.
The refractive index of the aqueous humor is n 1-1.3333, the refractive index of the lens is n 2-1.4160, the refractive index of the vitreous body is n 3-1.3333, and the lens thickness LT is 3.34 mm.
Anterior lens surface power: fa ═ (n 2-n 1)/Ca (where Ca is in meters);
and (3) outputting: anterior lens surface power: fa 6.52D
Lens posterior surface refractive power: fb ═ n 3-n 2/Cp (where Cp is in meters);
and (3) outputting: lens posterior surface refractive power: Fb-11.13D
Total refractive power of lens: ft is Fa + Fb-LT × Fa × Fb/n2 (where LT is in meters);
and (3) outputting: total refractive power of lens: ft is 17.82D
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and additions can be made without departing from the principle of the present invention, and these should also be considered as the protection scope of the present invention.
Claims (8)
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114027883A (en) * | 2021-11-08 | 2022-02-11 | 中山大学中山眼科中心 | Method, device and system for measuring biological parameters of lens |
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| WO2005030044A1 (en) * | 2003-09-23 | 2005-04-07 | Carl Zeiss Meditec Ag | Method for measuring an intraocular lens |
| CN101617966A (en) * | 2008-07-02 | 2010-01-06 | 南开大学 | After-cornea refractive surgery artificial lens design |
| CN110123488A (en) * | 2019-05-27 | 2019-08-16 | 中国计量科学研究院 | Intraocular lens' diopter Test lenses and valued methods |
| CN111653364A (en) * | 2020-07-09 | 2020-09-11 | 王世明 | Intraocular lens refractive power calculation method and device |
| CN112120666A (en) * | 2020-10-14 | 2020-12-25 | 上海爱尔眼科医院有限公司 | Lens refractive power measuring and calculating method, device, equipment and storage medium |
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- 2021-02-01 CN CN202110136724.9A patent/CN112957004B/en active Active
Patent Citations (5)
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| WO2005030044A1 (en) * | 2003-09-23 | 2005-04-07 | Carl Zeiss Meditec Ag | Method for measuring an intraocular lens |
| CN101617966A (en) * | 2008-07-02 | 2010-01-06 | 南开大学 | After-cornea refractive surgery artificial lens design |
| CN110123488A (en) * | 2019-05-27 | 2019-08-16 | 中国计量科学研究院 | Intraocular lens' diopter Test lenses and valued methods |
| CN111653364A (en) * | 2020-07-09 | 2020-09-11 | 王世明 | Intraocular lens refractive power calculation method and device |
| CN112120666A (en) * | 2020-10-14 | 2020-12-25 | 上海爱尔眼科医院有限公司 | Lens refractive power measuring and calculating method, device, equipment and storage medium |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114027883A (en) * | 2021-11-08 | 2022-02-11 | 中山大学中山眼科中心 | Method, device and system for measuring biological parameters of lens |
| CN114027883B (en) * | 2021-11-08 | 2023-06-23 | 中山大学中山眼科中心 | Method, device and system for measuring biological parameters of crystalline lens |
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