CN101612290A - A kind of pharmaceutical composition for the treatment of burn and scald and preparation method thereof - Google Patents
A kind of pharmaceutical composition for the treatment of burn and scald and preparation method thereof Download PDFInfo
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- CN101612290A CN101612290A CN200810115749A CN200810115749A CN101612290A CN 101612290 A CN101612290 A CN 101612290A CN 200810115749 A CN200810115749 A CN 200810115749A CN 200810115749 A CN200810115749 A CN 200810115749A CN 101612290 A CN101612290 A CN 101612290A
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Abstract
The present invention discloses a kind of pharmaceutical composition for the treatment of burn and scald, and said composition is made up of first group of medicine Radix Arnebiae (Radix Lithospermi), Radix Ilicis Pubescentis, Radix Sanguisorbae, Flos Lonicerae, Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Mel and second group of medicine Gypsum Fibrosum Preparatum, the Pseudobulbus Bletillae (Rhizoma Bletillae), Borneolum Syntheticum.Pharmaceutical composition of the present invention adds the exterior-applied formulation that conventional adjuvant is made clinical acceptance by practice of pharmacy, as spray, emplastrum, ointment, powder or liniment etc.Pharmaceutical composition of the present invention has anti-inflammatory analgetic, heat-clearing and toxic substances removing, and activating blood circulation to dissipate blood stasis, granulation promoting is held back the effect of skin, has easy to usely, and curative effect is fast, need not wrap up and make skin graft, do not have cicatrix or cicatrix is not obvious, characteristics such as no scratchiness.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition and preparation method thereof, particularly relate to a kind of pharmaceutical composition for the treatment of burn and scald and preparation method thereof.
Background technology
Burn and to scald be one of disease of serious harm human health, be by action of chemicals such as flame, hot water, steam, electric current, lonizing radiation, laser, strong acid or highly basic in the caused damage of human body, clinical common, Therapeutic Method is varied.Burn and scald mostly occur in the skin surface and the deep tissues of human body, can be divided into I, II, III degree by burning the degree of depth, burn and scald causes very easily that skin table bacterial infection, body fluid exosmose, skin deformation, leave over cicatrix, and serious can cause hyperpyrexia, shock, threat to life even.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition for the treatment of burn and scald.
Another purpose of the present invention is to provide a kind of preparation of drug combination method and purposes for the treatment of burn and scald.
The present invention is achieved through the following technical solutions:
The crude drug of pharmaceutical composition of the present invention consists of:
First group:
Radix Arnebiae (Radix Lithospermi) 75-225 weight portion Radix Ilicis Pubescentis 150-450 weight portion Radix Sanguisorbae 150-450 weight portion
Flos Lonicerae 100-300 weight portion Rhizoma Coptidis 50-150 weight portion Cortex Phellodendri 50-150 weight portion
Radix Et Rhizoma Rhei 60-180 weight portion
Second group:
Gypsum Fibrosum Preparatum 150-450 weight portion Pseudobulbus Bletillae (Rhizoma Bletillae) 50-150 weight portion Borneolum Syntheticum 12-37 weight portion.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
First group:
Radix Arnebiae (Radix Lithospermi) 150 weight portion Radix Ilicis Pubescentiss 300 weight portion Radix Sanguisorbaes 300 weight portions
Flos Lonicerae 200 weight portion Rhizoma Coptidis 100 weight portion Cortex Phellodendris 100 weight portions
Radix Et Rhizoma Rhei 120 weight portions
Second group:
The Gypsum Fibrosum Preparatum 300 weight portion Pseudobulbus Bletillae (Rhizoma Bletillae)s 100 weight portion Borneolum Syntheticums 25 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
First group:
Radix Arnebiae (Radix Lithospermi) 80 weight portion Radix Ilicis Pubescentiss 440 weight portion Radix Sanguisorbaes 160 weight portions
Flos Lonicerae 290 weight portion Rhizoma Coptidis 60 weight portion Cortex Phellodendris 140 weight portions
Radix Et Rhizoma Rhei 70 weight portions
Second group:
The Gypsum Fibrosum Preparatum 160 weight portion Pseudobulbus Bletillae (Rhizoma Bletillae)s 140 weight portion Borneolum Syntheticums 16 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
First group:
Radix Arnebiae (Radix Lithospermi) 215 weight portion Radix Ilicis Pubescentiss 160 weight portion Radix Sanguisorbaes 440 weight portions
Flos Lonicerae 110 weight portion Rhizoma Coptidis 140 weight portion Cortex Phellodendris 60 weight portions
Radix Et Rhizoma Rhei 160 weight portions
Second group:
The Gypsum Fibrosum Preparatum 440 weight portion Pseudobulbus Bletillae (Rhizoma Bletillae)s 60 weight portion Borneolum Syntheticums 33 weight portions.
Pharmaceutical composition of the present invention adds the exterior-applied formulation that conventional adjuvant is made clinical acceptance by practice of pharmacy: spray, emplastrum, ointment, powder or liniment.
Preparation of drug combination method of the present invention is: first group of crude drug adds water 8000-12000 weight portion, put into the pot boiled after, removed slag in 2-4 at a simmer hour, again the continuation shorten 4000-6000 weight portion medicinal liquid into at a simmer inspissating, add 150-450 weight portion Mel, mix thoroughly; Second group of crude drug porphyrize is placed in the container that disinfects, first group of medicinal liquid of making poured in the container, stir together, seal 1.5-2.5 up for safekeeping after individual month, the use of can bottling.
Preparation of drug combination method of the present invention is preferably: first group of crude drug adds water 10000 weight portions, put into the pot boiled after, remove slag after 3 hours at a simmer, again the continuation shorten 5000 weight portions into at a simmer inspissating, add 300 weight portion Mel, mix thoroughly; Second group of crude drug porphyrize is placed in the container that disinfects, first group of medicinal liquid of making poured in the molten device, stir together, seal 2 months up for safekeeping after, the use of can bottling.
Pharmaceutical composition of the present invention be the inventor on the basis of secret recipe handed down in the family, by the clinical practice of three more than ten years, develop, directly be sprayed onto the affected part after the sterilization, the very fast separation of slough is come off, analgesic effect rapidly and significantly, have no side effect, patient takes like a shot.Pharmaceutical composition of the present invention has anti-inflammatory analgetic, heat-clearing and toxic substances removing, and activating blood circulation to dissipate blood stasis, granulation promoting is held back the skin effect.Pharmaceutical composition of the present invention has easy to use, and curative effect is fast, need not wrap up and make skin graft, do not have cicatrix or cicatrix is not obvious, characteristics such as no scratchiness.
Following experimental example and embodiment further specify the present invention but are not limited to the present invention:
By 647 routine burn and scald patients being used the treatment behind the pharmaceutical composition of the present invention observe, effect is very satisfied, now is reported as follows:
1, clinical data
Case is totally 647 examples, all from January, 2007 to 2007 year December, wherein male 391 examples, women 256 examples; The oldest 82 years old, minimum 1 years old; The course of disease is the longest 23 days, and 3 examples are arranged, and is the shortest 4 days, and 15 examples are arranged.
2, Therapeutic Method and result
2.1 prescription is formed:
First group:
Radix Arnebiae (Radix Lithospermi) 150 gram Radix Ilicis Pubescentiss 300 gram Radix Sanguisorbaes 300 grams
Flos Lonicerae 200 gram Rhizoma Coptidis 100 gram Cortex Phellodendris 100 grams
Radix Et Rhizoma Rhei 120 grams
Second group:
The Gypsum Fibrosum Preparatum 300 gram Pseudobulbus Bletillae (Rhizoma Bletillae)s 100 gram Borneolum Syntheticums 25 grams.
2.2 preparation method
First group of medicine adds 10 kilograms in water, put into the pot boiled after, remove slag after 3 hours at a simmer, continue again to shorten 5 kilograms into, add 300 gram Mel with at a simmer inspissating, mix thoroughly, then second group of medicine porphyrize is placed in the container that disinfects, first group of medicinal liquid of making poured in the molten device, stir together, after sealing 2 months up for safekeeping, the use of can bottling.
2.3 using method:
Add medicine to after the sterilization debridement earlier for the first time, the spray medicine was once up to recovery from illness in later 1-2 hour.
3, criterion of therapeutical effect
Cure: symptom and skin lesion all disappear;
Effectively: symptom obviously alleviates with skin lesion and goes down＞and 30%;
Invalid: sx or skin lesion disappear＜and 30%.
4, therapeutic outcome sees Table 1:
The clinical data table of diseases such as table 1 medicine composite for curing burn and scald of the present invention
| Criterion of therapeutical effect | Cure (routine number) | Effectively (routine number) | Invalid (routine number) |
| Burn | ??57 | ??38 | ??0 |
| Scald | ??289 | ??225 | ??0 |
| Chemical injury | ??21 | ??17 | ??0 |
| Effective percentage | ??57％ | ??43％ | ??0 |
To sum up, medicine composite for curing burn and scald 647 routine clinical observations of the present invention, treatment burn, scald, chemical injury cure rate 57%, effective percentage 43%, total effective rate 100%.
5, model case
1, the week * * women Si Gang town shoal wire rope factory work, fall in the boiled water of phosphatization pond (poisonous), scald 45%, the degree of depth 2 degree (photo is arranged) belong to large tracts of land and scald, and through using medicinal composition spray of the present invention, fully recover no cicatrix in 10 days.
2, huge * * women pool people from town, liquefied gas burn whole body, the whole body burn surface area surpasses 50%, the dark 2 degree burns of two lower limb belong to large-area burns, fully recover after 20 days through using pharmaceutical composition emplastrum of the present invention, more after no scratchiness.The lower limb photo of clapping after 1 year is very clear, and upper limb, face, cervical region do not have cicatrix.
3, open * * pool city China spins the worker of group, and because of falling into dye vat rear left-leg rats after severe scald burn (dark 2 degree are scalded) accidentally,, treat after 20 days and fully recover through using medicinal composition powders of the present invention.
4, normal * * Yang She Sichuan hotel worker, because of the pressure cooker facial rats after severe scald burn of exploding, through using pharmaceutical composition liniment treatment of the present invention recovery from illness after 4 days, face does not stay cicatrix.
Following embodiment is used to further specify the present invention:
The specific embodiment:
Embodiment 1:
First group:
Radix Arnebiae (Radix Lithospermi) 150 gram Radix Ilicis Pubescentiss 300 gram Radix Sanguisorbaes 300 grams
Flos Lonicerae 200 gram Rhizoma Coptidis 100 gram Cortex Phellodendris 100 grams
Radix Et Rhizoma Rhei 120 grams
Second group:
The Gypsum Fibrosum Preparatum 300 gram Pseudobulbus Bletillae (Rhizoma Bletillae)s 100 gram Borneolum Syntheticums 25 grams.
Get first group of crude drug of aforementioned pharmaceutical compositions and add 10 kilograms in water, put into the pot boiled after, remove slag after 3 hours at a simmer, continue again to shorten 5 kilograms into, add 300 gram Mel with at a simmer inspissating, mix thoroughly, second group of crude drug porphyrize is placed in the container that disinfects, first group of medicinal liquid of making poured in the molten device, stir together, after sealing 2 months up for safekeeping, the use of can bottling.Spray three times continuously after the partly sterilised, spraying in later every 2-4 hour is not wrapped up, is made skin graft.
Embodiment 2:
First group:
Radix Arnebiae (Radix Lithospermi) 150 gram Radix Ilicis Pubescentiss 300 gram Radix Sanguisorbaes 300 grams
Flos Lonicerae 200 gram Rhizoma Coptidis 100 gram Cortex Phellodendris 100 grams
Radix Et Rhizoma Rhei 120 grams
Second group:
The Gypsum Fibrosum Preparatum 300 gram Pseudobulbus Bletillae (Rhizoma Bletillae)s 100 gram Borneolum Syntheticums 25 grams.
Said medicine adds the emplastrum that conventional adjuvant is made clinical acceptance by practice of pharmacy.
Embodiment 3:
First group:
Radix Arnebiae (Radix Lithospermi) 80 gram Radix Ilicis Pubescentiss 440 gram Radix Sanguisorbaes 160 grams
Flos Lonicerae 290 gram Rhizoma Coptidis 60 gram Cortex Phellodendris 140 grams
Radix Et Rhizoma Rhei 70 grams
Second group:
The Gypsum Fibrosum Preparatum 160 gram Pseudobulbus Bletillae (Rhizoma Bletillae)s 140 gram Borneolum Syntheticums 16 grams.
Said medicine adds the ointment that conventional adjuvant is made clinical acceptance by practice of pharmacy.
Embodiment 4:
First group:
Radix Arnebiae (Radix Lithospermi) 215 gram Radix Ilicis Pubescentiss 160 gram Radix Sanguisorbaes 440 grams
Flos Lonicerae 110 gram Rhizoma Coptidis 140 gram Cortex Phellodendris 60 grams
Radix Et Rhizoma Rhei 160 grams
Second group:
The Gypsum Fibrosum Preparatum 440 gram Pseudobulbus Bletillae (Rhizoma Bletillae)s 60 gram Borneolum Syntheticums 33 grams.
Said medicine adds the liniment that conventional adjuvant is made clinical acceptance by practice of pharmacy.
Embodiment 5:
First group:
Radix Arnebiae (Radix Lithospermi) 215 gram Radix Ilicis Pubescentiss 160 gram Radix Sanguisorbaes 440 grams
Flos Lonicerae 110 gram Rhizoma Coptidis 140 gram Cortex Phellodendris 60 grams
Radix Et Rhizoma Rhei 160 grams
Second group:
The Gypsum Fibrosum Preparatum 440 gram Pseudobulbus Bletillae (Rhizoma Bletillae)s 60 gram Borneolum Syntheticums 33 grams.
Said medicine adds the powder that conventional adjuvant is made clinical acceptance by practice of pharmacy.
Claims (9)
1, a kind of pharmaceutical composition for the treatment of burn and scald is characterized in that the crude drug of said composition consists of:
First group:
Radix Arnebiae (Radix Lithospermi) 75-225 weight portion Radix Ilicis Pubescentis 150-450 weight portion Radix Sanguisorbae 150-450 weight portion
Flos Lonicerae 100-300 weight portion Rhizoma Coptidis 50-150 weight portion Cortex Phellodendri 50-150 weight portion
Radix Et Rhizoma Rhei 60-180 weight portion
Second group:
Gypsum Fibrosum Preparatum 150-450 weight portion Pseudobulbus Bletillae (Rhizoma Bletillae) 50-150 weight portion Borneolum Syntheticum 12-37 weight portion.
2, pharmaceutical composition according to claim 1 is characterized in that the crude drug of said composition consists of:
First group:
Radix Arnebiae (Radix Lithospermi) 150 weight portion Radix Ilicis Pubescentiss 300 weight portion Radix Sanguisorbaes 300 weight portions
Flos Lonicerae 200 weight portion Rhizoma Coptidis 100 weight portion Cortex Phellodendris 100 weight portions
Radix Et Rhizoma Rhei 120 weight portions
Second group:
The Gypsum Fibrosum Preparatum 300 weight portion Pseudobulbus Bletillae (Rhizoma Bletillae)s 100 weight portion Borneolum Syntheticums 25 weight portions.
3, pharmaceutical composition according to claim 1 is characterized in that the crude drug of said composition consists of:
First group:
Radix Arnebiae (Radix Lithospermi) 80 weight portion Radix Ilicis Pubescentiss 440 weight portion Radix Sanguisorbaes 160 weight portions
Flos Lonicerae 290 weight portion Rhizoma Coptidis 60 weight portion Cortex Phellodendris 140 weight portions
Radix Et Rhizoma Rhei 70 weight portions
Second group:
The Gypsum Fibrosum Preparatum 160 weight portion Pseudobulbus Bletillae (Rhizoma Bletillae)s 140 weight portion Borneolum Syntheticums 16 weight portions.
4, pharmaceutical composition according to claim 1 is characterized in that the crude drug of said composition consists of:
First group:
Radix Arnebiae (Radix Lithospermi) 215 weight portion Radix Ilicis Pubescentiss 160 weight portion Radix Sanguisorbaes 440 weight portions
Flos Lonicerae 110 weight portion Rhizoma Coptidis 140 weight portion Cortex Phellodendris 60 weight portions
Radix Et Rhizoma Rhei 160 weight portions
Second group:
The Gypsum Fibrosum Preparatum 440 weight portion Pseudobulbus Bletillae (Rhizoma Bletillae)s 60 weight portion Borneolum Syntheticums 33 weight portions.
5,, it is characterized in that this preparation of drug combination method is according to the described pharmaceutical composition of one of claim 1-4:
First group of crude drug adds water 8000-12000 weight portion, put into the pot boiled after, removed slag in 2-4 at a simmer hour, and continued again to shorten 4000-6000 weight portion medicinal liquid into, add 150-450 weight portion Mel with at a simmer inspissating, mix thoroughly, second group of crude drug porphyrize is placed in the container that disinfects, first group of medicinal liquid of making poured in the container, stir together, after sealing 1.5-2.5 month up for safekeeping, the use of can bottling.
6, preparation of drug combination method according to claim 5 is characterized in that this method is:
First group of crude drug adds water 10000 weight portions, put into the pot boiled after, remove slag after 3 hours at a simmer, continue again to shorten 5000 weight portions into, add 300 weight portion Mel with at a simmer inspissating, mix thoroughly, second group of crude drug porphyrize is placed in the container that disinfects, first group of medicinal liquid of making poured in the molten device, stir together, after sealing 2 months up for safekeeping, the use of can bottling.
7,, it is characterized in that said composition adds the exterior-applied formulation that conventional adjuvant is made clinical acceptance by practice of pharmacy according to the described pharmaceutical composition of one of claim 1-4.
8, pharmaceutical composition according to claim 7 is characterized in that described exterior-applied formulation is spray, emplastrum, ointment, powder or liniment.
9, according to the application of the described pharmaceutical composition of one of claim 1-4 in the medicine of preparation treatment burn and scald.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101157495A CN101612290B (en) | 2008-06-27 | 2008-06-27 | Medicinal composition for treating burn and scald and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101157495A CN101612290B (en) | 2008-06-27 | 2008-06-27 | Medicinal composition for treating burn and scald and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101612290A true CN101612290A (en) | 2009-12-30 |
| CN101612290B CN101612290B (en) | 2012-11-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008101157495A Expired - Fee Related CN101612290B (en) | 2008-06-27 | 2008-06-27 | Medicinal composition for treating burn and scald and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102018742A (en) * | 2010-11-17 | 2011-04-20 | 盘吉荣 | Externally applied traditional Chinese medicine for treating burns and preparation method thereof |
| CN102058781A (en) * | 2010-12-24 | 2011-05-18 | 林栋� | Traditional Chinese medicinal film agent for treating burns and scalds |
| CN103230470A (en) * | 2013-05-06 | 2013-08-07 | 湖南省宝灵医药器械有限公司 | Traditional Chinese medicine preparation for treating burns and scalds and preparation method thereof |
| CN106620276A (en) * | 2017-03-16 | 2017-05-10 | 金德培 | Preparation method for Chinese herbal and Western medicine external-use powder, ointment and agent for therapy of burn and scald |
| CN109157652A (en) * | 2018-09-21 | 2019-01-08 | 珠海汉盈科技有限公司 | The spontaneous hotting mask of promotion burn wound reparation containing Radix Arnebiae extract |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000114124A (en) * | 1998-10-07 | 2000-04-21 | Jcc Engineering Kk | Electrolyte vacuum impregnation method and equipment of electrolytic capacitor element |
| CN100350951C (en) * | 2005-02-05 | 2007-11-28 | 崔润生 | External-applied medicine for treating burn, valnus and local tumor inflammation |
| CN100518794C (en) * | 2006-08-21 | 2009-07-29 | 王开贞 | Burn cream |
-
2008
- 2008-06-27 CN CN2008101157495A patent/CN101612290B/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102018742A (en) * | 2010-11-17 | 2011-04-20 | 盘吉荣 | Externally applied traditional Chinese medicine for treating burns and preparation method thereof |
| CN102058781A (en) * | 2010-12-24 | 2011-05-18 | 林栋� | Traditional Chinese medicinal film agent for treating burns and scalds |
| CN102058781B (en) * | 2010-12-24 | 2012-09-12 | 林栋� | Traditional Chinese medicinal film agent for treating burns and scalds |
| CN103230470A (en) * | 2013-05-06 | 2013-08-07 | 湖南省宝灵医药器械有限公司 | Traditional Chinese medicine preparation for treating burns and scalds and preparation method thereof |
| CN103230470B (en) * | 2013-05-06 | 2015-09-09 | 湖南省宝灵医药器械有限公司 | A kind of Chinese medicine for outer use for the treatment of burn and scald and preparation method thereof |
| CN106620276A (en) * | 2017-03-16 | 2017-05-10 | 金德培 | Preparation method for Chinese herbal and Western medicine external-use powder, ointment and agent for therapy of burn and scald |
| CN109157652A (en) * | 2018-09-21 | 2019-01-08 | 珠海汉盈科技有限公司 | The spontaneous hotting mask of promotion burn wound reparation containing Radix Arnebiae extract |
Also Published As
| Publication number | Publication date |
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| CN101612290B (en) | 2012-11-21 |
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