CN101612275B - Traditional Chinese medicine for treating nephrotic syndrome and preparation method thereof - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating nephrotic syndrome, comprising the following components by weight portion: 90-150 portions of umbellate pore furgus, 50-90 portions of mangnolia officinalis, 10-60 portions of unprocessed rhizoma pinelliae, 10-60 portions of ginseng and 10-60 portions of ligusticum wallichii. The traditional Chinese medicine is prepared from hundreds of selected traditional Chinese medicines, has reasonable collocation and accurate medication, achieves the purposes of supporting healthy energy and treating the primary and the secondary aspects at the same time through the function of mutual cooperation among the medicines, and does not have any toxic or side effect. The invention adjusts the systemic immune function by tonifying the kidney, invigorating blood circulation and expelling toxin, restores glomerular basement membrane, eliminates immune complex, lightens or eliminates urokinase protein and occult blood, promotes renal microcirculation, fastens renal metabolism, actives renal units, enables kidney to restore normal size, strengthens detoxification function, and enables toxin of serum creatinine, urea nitrogen, and the like to be exhausted from urine.

Description

Chinese medicine of the treatment nephrotic syndrome and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition, especially relate to a kind of Chinese medicine for the treatment of the nephrotic syndrome and preparation method thereof.

Background technology

The nephrotic syndrome is in early days based on a large amount of albuminuria, and uncomfortable symptom is not obvious.But along with the intrinsic cell of kidney injury is on the increase, scope enlarges gradually, and edema can appear in proteic spilling in a large number.As can not get effective treatment and can cause renal insufficiency even uremia.Western medicines such as hormone, immunosuppressant are generally adopted in the treatment of the nephrotic syndrome at present, not only are very easy to recurrence, and albuminuria occurs repeatedly, and Western medicine is very big to people's side effect.

Summary of the invention

The technical problem to be solved in the present invention provides a kind of Chinese medicine for the treatment of the nephrotic syndrome and preparation method thereof, and this Chinese medicine has instant effect, therapeutic effect is obvious, cost is low characteristics.

In order to solve the problem that prior art exists, the technical solution used in the present invention is:

The Chinese medicine of the treatment nephrotic syndrome is made up of following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=90-150: 50-90: 10-60: 10-60: 10-60 according to the following number of weight ratio.

The Chinese medicine of the described treatment nephrotic syndrome is made up of following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=120: 70: 30: 30: 30 according to the following number of weight ratio.

Prepare the method for the Chinese medicine of the described treatment nephrotic syndrome, may further comprise the steps:

1. above-mentioned each single medicinal material is pulverized with pulverizer, crossed 100 mesh sieves;

2. get the abundant mixing of each single medicinal material after the pulverizing according to the above ratio.

The preferred dosage form of medicine of the present invention is a powder, but be not limited only to this, also can adopt the conventional method of Chinese medicine preparation to make any conventional oral formulations, as dosage forms such as tablet, capsule, powder, granule, oral liquid, syrup, Emulsion, soft capsule, suspensoids.But these can not be used for limiting protection scope of the present invention.

Advantage and effect that the present invention had are:

Because the pathogenesis of nephropathy is that heresy is just struggled against, simulataneous insufficiency and excessive, negative and positive are lost empty, and therefore, the total Therapeutic Principle of nephropathy is: strengthening vital QI to eliminate pathogenic factors, giving consideration to both the incidental and fundamental; Coordinating YIN and YANG, the pathological change of getting in touch other the bottom of hearts is carried out dialectical opinion and is controlled.Strengthening vital QI to eliminate pathogenic factors is also executed giving consideration to both the incidental and fundamental; The Heibei provincial opera negative and positive are worked as treating YANG within YIN, treating YIN within YANG; Adjust the bottom of heart.Medicine of the present invention is to form from hundreds of Chinese medicine is selected, arranges in pairs or groups rationally between the medicine, and medication is accurate, by the mutual compatibility effect between the medicine, reaches strengthening the body resistance, treating both the principal and secondary aspects of a disease purpose, without any toxic and side effects.By the kidney invigorating, invigorate blood circulation, toxin expelling regulates the general immunity function, repairs glomerular basement membrane, removes immune complex, alleviate or eliminate urine protein, occult blood.Promote the kidney microcirculation, quicken the kidney metabolism, activate nephron, make the atrophy kidney recover normal size, strengthen functions of expelling toxin, toxin such as serum creatinine, blood urea nitrogen are discharged from urine.Cortex Magnoliae Officinalis nature and flavor hardship, suffering, temperature.Return spleen, stomach, lung, large intestine channel, have the dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is removed full function.Rhizoma Pinelliae nature and flavor suffering, temperature; Poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass.The Polyporus nature and flavor are sweet, light, flat, return kidney, urinary bladder channel.Have diuresis eliminating dampness by diuresis function, be used for dysuria, edema is had loose bowels, diseases such as stranguria with turbid discharge leukorrhagia.Radix Ginseng is sweet in flavor and warm in property, is mainly used in the deficiency of vital energy, as a little less than the empty gas of body, a little less than the prolonged illness gas or overfatigue etc.Mend gas-solid film, the spleen invigorating lung benefiting, mind calming Fructus Alpiniae Oxyphyllae, health preserving promote the production of body fluid, cure mainly serious disease, prolonged illness, lose blood, take off due to the liquid vigour desires to take off, the Mental fatigue faint pulse, the lack of appetite asthenia of deficiency of spleen-QI, the dyspnea with shortness of breath of insufficiency of lung-QI, the empty hyperhidrosis of body, blood deficiency sallow, dizzy, suffer from a deficiency of the kidney etc.Rhizoma Chuanxiong character suffering, temperature are returned liver, gallbladder meridian, have the effect of blood-activating and qi-promoting, wind-expelling pain-stopping, are " the gas medicine in the blood ".

Since 2002, medicine of the present invention is treated nephrotic syndrome patient 200 examples altogether, male patient's 135 examples wherein, routine patient's 65 examples of woman, wherein the patient of age minimum is 15 years old, and oldest patient 75 years old has 5 conditions of patients to take a turn for the better to some extent among the above-mentioned patient, but do not reach the clinical cure standard, all the other 195 patients all cure.

Model case:

Lee, the woman, 27 years old, people from Jinzhou City, during in March, 2006 first visit: two lower limb refer to the concavity edema, hypourocrinia, foam is more, chemical examination urine Rt:PRO (++ ++), BLD (-) is diagnosed as nephrotic syndrome.Begin to take drug powder of the present invention and treat, once a day, each 1 gram, warm water delivery service; Treating three months is a course of treatment.Take medicine of the present invention after 30 days, patient's edema of pair of lower extremities obviously alleviates, and anasarca disappears after the course of treatment, the urine color burn, abnormal smells from the patient increases the weight of, chemical examination urine Rt:PRO (±), patient continue to take medicine consolidate 1 course of treatment after, follow up a case by regular visits to not recurrence in a year.

The Wang, the woman, 48 years old, the Fuxin City people, the albumen that has urine examined in March, 2005 (++ ++), albumin 13g/1, triglyceride and T-CHOL raise, and are diagnosed as the nephrotic syndrome, though the edema degree alleviates after hormone therapy, do not disappear fully, and patient's ascites are obvious.Then begin to take drug powder of the present invention and treat in October, 2005, once a day, each 1 gram, warm water delivery service; Three months is a course of treatment.After taking 1 course of treatment, patient face and edema of pair of lower extremities disappear, and nervous sense uncomfortable in chest disappears, the albumen (-) that has urine examined, and albumin 29g/l, triglyceride and T-CHOL are reduced to normal level.

Jiang, the man, 46 years old, people from Shenyang City, two eyelids of patient's discontinuity and edema of pair of lower extremities are looked into albumin 15.5g/L during in January, 2004 first visit, the white white 10g/L of red eggs, urine protein (+++).Twenty-four-hour urine protein quantification 4.19/24 hour, the ascites feminine gender is diagnosed as the nephrotic syndrome, and begin to take drug powder of the present invention and treat, once a day, each 1 gram, warm water delivery service; Three months is a course of treatment.After taking 1 course of treatment, patient's anasarca disappears, and pleural effusions and ascites disappears fully, serum creatinine 173 μ mol/L.

The specific embodiment

Embodiment 1:

The Chinese medicine of the treatment nephrotic syndrome is made up of following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=150: 50: 10: 10: 10 according to the following number of weight ratio.

The preparation method of Chinese medicine of the treatment nephrotic syndrome may further comprise the steps:

1. above-mentioned each single medicinal material is pulverized with pulverizer, crossed 100 mesh sieves;

2. get the abundant mixing of each single medicinal material after the pulverizing according to the above ratio.

Embodiment 2:

The Chinese medicine of the treatment nephrotic syndrome is made up of following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=90: 90: 60: 60: 60 according to the following number of weight ratio.Its preparation method is with embodiment 1.

Embodiment 3:

The Chinese medicine of the treatment nephrotic syndrome is made up of following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=120: 70: 30: 30: 30 according to the following number of weight ratio.Its preparation method is with embodiment 1.

Embodiment 4:

The Chinese medicine of the treatment nephrotic syndrome is made up of following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=100: 60: 50: 40: 50 according to the following number of weight ratio.Its preparation method is with embodiment 1.

Embodiment 5:

The Chinese medicine of the treatment nephrotic syndrome is made up of following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=130: 80: 20: 30: 40 according to the following number of weight ratio.

Its preparation method is with embodiment 1.

Claims (3)

1. the Chinese medicine of the treatment nephrotic syndrome is characterized in that being made up of according to the following number of weight ratio following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=90-150: 50-90: 10-60: 10-60: 10-60.

2. the Chinese medicine of the treatment nephrotic syndrome according to claim 1 is characterized in that being made up of according to the following number of weight ratio following component: Polyporus: Cortex Magnoliae Officinalis: Rhizoma Pinelliae: Radix Ginseng: Rhizoma Chuanxiong=120: 70: 30: 30: 30.

3. prepare the method for the Chinese medicine of the described treatment nephrotic syndrome of claim 1, it is characterized in that may further comprise the steps:

1. above-mentioned each single medicinal material is pulverized with pulverizer, crossed 100 mesh sieves;

2. get the abundant mixing of each single medicinal material after the pulverizing according to the above ratio.