CN101601768A - A kind of Chinese medicine composition for the treatment of tinea pedis, scabies and preparation method thereof - Google Patents
A kind of Chinese medicine composition for the treatment of tinea pedis, scabies and preparation method thereof Download PDFInfo
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- CN101601768A CN101601768A CNA2009100654828A CN200910065482A CN101601768A CN 101601768 A CN101601768 A CN 101601768A CN A2009100654828 A CNA2009100654828 A CN A2009100654828A CN 200910065482 A CN200910065482 A CN 200910065482A CN 101601768 A CN101601768 A CN 101601768A
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Abstract
The invention belongs to technical field of Chinese medicines, specifically disclose a kind of Chinese medicine composition for the treatment of tinea pedis, scabies and preparation method thereof.Described compositions is mainly made by each crude drug of following weight proportioning: Cortex Pseudolaricis 3～15g, sulfur 3～9g, Calomelas 1～3g, Camphora 1～6g, Radix Sophorae Flavescentis 3～15g, Pericarpium Zanthoxyli 1～9g.After the above-mentioned raw materials medicine ground to the powder altogether, add medical alcohol 200～500ml, soaked 2～7 days, get its soak and promptly get lotion.Chinese medicine composition of the present invention directly is applied to the affected part, through sick institute, determined curative effect, be difficult for recurrence with the back, also very simple, the easy row of preparation method all has significant curative effect to tinea pedis and scabies, the effective percentage of treatment tinea pedis is 93.3%, and the effective percentage of treatment scabies is 90.2%.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of tinea pedis, scabies and preparation method thereof.
Background technology
Tinea pedis is born in toes, by damp invasion of lower energizer or contact noxious dampness pathogen and sending out.First sick interdigit has little water kitchen, very itches, and flowing water then after galling, can there be desquamation or incrustation in the part.Wet mashed because of doing repeatedly between toe, so title " water burst skin ulcer " again.Tinea pedis whenever easily has secondary infection, and the serious symptom transudate significantly increases, and off-odor is arranged, near local skin (bending the nearly toe root of side to seeing with toes) easily intertrigo exposes red rotten to the corn face more, and the part is gradually swollen, even company and sufficient face, by name " smelly Cipangopaludina chinensis " also has and is " tinea pedis ".Other has a kind of tinea pedis, dried itching between toe, and the coarse desquamation of local skin when weather is cold, occurs chapping easily.Tinea pedis often can be divided into following 3 types according to the performance of its skin lesion, but the three can occur simultaneously or alternately, or based on a certain type: 1. squama vesicle type, the most common, often between toe, syringe needle size papulovesicle and herpes appear in the sufficient sole of the foot and lateral margin repeatedly thereof, assemble or be dispersed in, wall thickness is shinny, inflammatory reaction and pruritus are in various degree arranged, and bleb is done the back desquamation, is little eckband shape or large stretch of shape, constantly come off, constantly take place, during stable disease, often show as the master with desquamation; 2. the dipping erosive type is common between the 4th, the 5th toe, and horny layer floods, turns white, soft, strips off and exposes red rotten to the corn face or honeycomb substrate, a little sepage can be arranged, the easy secondary infection of this type, concurrent acute lymphangitis, lymphadenitis and erysipelas etc.; 3. hyperkeratotic pattern is common in sufficient root, the sufficient sole of the foot and lateral margin thereof, cuticle thickening, coarse, desquamation, drying, and subjective symptoms is slight, easily chaps every winter, and this type often betides that stadium is long, longer patient of age.
Scabies is the contagious infection dermatoses that is caused by sarcoptic mite.Sarcoptic mite belongs to the demodicid mite class, colonizes in people and the mammalian skin.Scabies can betide any age, and the men and women all can fall ill, good sending out in the side in the wrong, umbilicus week, hypogastric region, external genital, axillary fossa leading edge, groin, femoribus internus, buttocks and the female breast pleat place that refer to side, webs, Wrist elbow joint.The childhood infection scabies can involve head and whole skin.The course of disease sustainable several weeks are to the several months.The clinical symptoms of scabies is a skin urtication, occurs erythra such as little erythra, phlysis or incrustation simultaneously at the pruritus position.
The medicine a multitude of names that is used for the treatment of tinea pedis or scabies at present, but mostly specificity is too strong for these medicines, and all be symptomatic treatment, weak curative effect easily recurs.
Summary of the invention
For overcoming the deficiencies in the prior art part, the object of the present invention is to provide a kind of evident in efficacy, difficult recurrence in usefulness back, and can be used for the treatment of the Chinese medicine composition of tinea pedis and scabies simultaneously, the preparation method of said composition is provided simultaneously.
For achieving the above object, the technical scheme taked of the present invention is as follows:
A kind of Chinese medicine composition for the treatment of tinea pedis, scabies is mainly made by each crude drug of following weight proportioning: Cortex Pseudolaricis 3～15g, sulfur 3～9g, Calomelas 1～3g, Camphora 1～6g, Radix Sophorae Flavescentis 3～15g, Pericarpium Zanthoxyli 1～9g.
In the present composition: Cortex Pseudolaricis, the another name Cortex Pseudolaricis, warm in nature, acrid in the mouth, poisonous is returned lung, spleen channel, and killing parasites for relieving itching is used for the scabies pruritus; Sulfur also claims sulfur, and sour in the mouth, warm in nature has the effect of killing parasites for relieving itching; Calomelas, hot, cold, poisonous, return liver, kidney channel, have the effect of parasite killing, counteracting toxic substances; Camphora, hot, hot, go into the heart, spleen two warps, have sensible, parasite killing, pain relieving, ward off dirty effect; Radix Sophorae Flavescentis, cold in nature, bitter in the mouth is gone into liver, kidney, large intestine, small intestine meridian, has heat clearing and damp drying, the effect of parasite killing diuresis; Pericarpium Zanthoxyli, the another name Fructus Zanthoxyli, warm in nature, acrid in the mouth is included into spleen, stomach, kidney channel, has that fragrance is good for the stomach, an effect of warming spleen and stomach for dispelling cold, removing damp and stopping pain, parasite killing detoxifcation, removing dampness and killing parasites.Above Six-element medicine compatibility is played killing parasites for relieving itching, removing dampness is held back skin ulcer, warming and odynolysis, had one's ideas straightened out and ward off dirty effect altogether.
Further, for obtaining optimum curative effect, on above-mentioned raw materials medicine compatibility basis, can also be added with calcined Alumen 3～9g, Realgar 3～9g, the Radix Stemonae 3～15g, Semen Hydnocarpi 3～9g in the described compositions.Wherein, calcined Alumen, the another name dried Alumen, sour, puckery, poisonous, go into lung, spleen, stomach, large intestine channel, have dampness, detoxifcation, parasiticidal effect; Realgar, warm in nature, acrid in the mouth is returned liver, large intestine channel, and is poisonous, has the effect of detoxifcation parasite killing; The Radix Stemonae, sweet-bitter flavor, slightly warm in nature, delousing parasite killing; Semen Hydnocarpi (Semen Hydnocarpi is commonly called as Semen Hydnocarpi), hot in nature, acrid in the mouth is gone into the liver,spleen,kidney warp, can be used for dispeling the wind counteracting toxic substances, parasite killing.
A kind of preparation method for the treatment of the Chinese medicine composition of tinea pedis, scabies, described method is carried out according to the following steps:
(1) in by weight/volume, take by weighing Cortex Pseudolaricis 3～15g, sulfur 3～9g, Calomelas 1～3g, Camphora 1～6g, Radix Sophorae Flavescentis 3～15g, Pericarpium Zanthoxyli 1～9g, medical alcohol 200～500ml, standby;
(2) the Six-element crude drug of step (1) is ground to the powder altogether after, add medical alcohol and soaked 2～7 days, get its soak and promptly get lotion.
Further, in the step (1), on the basis of Cortex Pseudolaricis, sulfur, Calomelas, Camphora, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli Six-element crude drug, add having taken by weighing calcined Alumen 3～9g, Realgar 3～9g, the Radix Stemonae 3～15g, Semen Hydnocarpi 3～9g in addition; In the step (2), with step (1) ten the flavor crude drug grind to the powder altogether.
When crude drug of the present invention ground to the powder altogether, the granularity of smalls generally was thin more good more, preferred 80～100 orders.Described medical alcohol is the ethanol of concentration 70%～75% (volume) commonly used as well known to those skilled in the art.
Using method: directly lotion of the present invention evenly is applied to the affected part, 2～3 times on the one, the each about 3～6ml in each affected part.
Clinical trial:
(1) physical data: accept out-patient's totally 202 examples for medical treatment, specifically be divided into two groups of tinea pedis and scabies, wherein, tinea pedis group 120 examples, male 44 examples, women 76 examples, minimum 15 years old of age, maximum 72 years old, the course of disease is the shortest 1 month, and was the longest 8 years, this group case foot all has skin lesion such as vesicle, erosion, hyperkeratosis and desquamation in various degree, vesicle type 32 examples wherein, erosive type 52 examples, hyperkeratotic pattern 36 examples; Scabies group 82 examples, male 56 examples, women 26 examples, at minimum 3 years old of age, maximum 62 years old, the course of disease was the shortest 2 days, has a surplus in the longest 1 year, and this group case all has the classical symptom of scabies: violent pruritus, meet the heat aggravation, night is more so.
(2) efficacy assessment standard:
Tinea pedis: recovery from illness: symptom and sign disappear, and it is normal that skin recovers; Produce effects: symptom obviously alleviates, and skin lesion disappears more than 50%, and the check fungus still has the positive; Invalid: symptom, sign do not have change.
Scabies: recovery from illness: pruritus control, erythra disappears, and does not have new rash and occurs, and only leaves over pigmented spots, color subtracts speckle or incrustation; Produce effects: pruritus significantly alleviates, and the erythra major part disappears; Invalid: pruritus alleviates, the still residual more person of erythra.
(3) administering mode and using method thereof: the tinea pedis group is with the lotion administration of embodiment 6, the scabies group directly evenly is applied to the affected part with the lotion administration of embodiment 5,2～3 times on the one, the once about 3～6ml in every place, general 3～4 days can produce effects or recovery from illness.
(4) therapeutic outcome: the tinea pedis group, 88 examples of fully recovering, produce effects 24 examples, invalid 8 examples, total effective rate is 93.3%; The scabies group, 58 examples of fully recovering, produce effects 16 examples, invalid 8 examples, total effective rate is 90.2%.
Model case
The tinea pedis group of case 1,2,3 is respectively with the liquid medicine administration of embodiment 4,1,2, the scabies group of case 3,4 is respectively with the liquid medicine administration of embodiment 2,3, dip in the water of getting it filled with absorbent cotton and directly evenly wipe in the affected part, 2～3 times on the one, the dosage in each affected part is controlled at 3～6ml at every turn.
Case 1 Zhang, man, 18 years old.Like ardently motion from childhood, originally just feel the frequent diaphoresis of foot after the motion, sticky paste, do not take notice of very much that seriously to two toes seams blister, diabrosis, erosion, pruritus, winter is lighter subsequently, summer is rotten to the corn red and swollen, such symptom 3 years surplus, be diagnosed as tinea pedis.After smearing 3 days with the liquid medicine of the present invention of embodiment 4, rotten to the corn place transudate obviously reduces, and the area that festers also obviously dwindles, and redness obviously alleviates, and continues logotype subsequently again 7 days, and congestion and swelling pain disappears, and recurrence is again followed up a case by regular visits to so far in the convalesce of festering.
Case 2 is permitted so-and-so, woman, 60 years old, peasant.There was squama phlysis in groups in toes portion when the patient went to a doctor, and broke, and pruritus is diagnosed as tinea pedis.Once attempted multi-treatment, to a certain degree curative effect all originally, but just recurrence again after drug withdrawal a period of time before.After upon somebody's introduction, the inventor locates to go to a doctor in March, 2009, smear 3 days with the liquid medicine of the present invention of embodiment 1 after, phlysis is just disappeared, and has not also itched, and recommends to continue medication subsequently again and consolidates a week, follows up a case by regular visits to so far and recurs again.
Case 3 kings so-and-so, the man, 28 years old, readme annual summer, phlysis appearred in two sufficient toes, and rotten to the corn, very itched and with the foot fetid sweat, during not diligent foot bath more so.Be diagnosed as tinea pedis, disease belongs in damp and hot strongly fragrant, controls suitable removing damp-heat, and the external embodiment of the invention 2 liquid medicine are clearly better after 3, and recovery from illness is followed up a case by regular visits to and do not seen recurrence so far after 10 days.
Case 4 Chens, man, 42 years old, the peasant, work out of the hometown for a long time, life live to be flowed, and feels the whole skin pruritus closely over the past half year, especially with the fossa cubitalis, axillary fossa for very, conscious play at night is itched and is difficult to fall asleep, and scratches brokenly back skin and is the red pimple of point-like, once external sulphur ointment voluntarily, symptom is slow slightly, but still can not fully recover.The inventor located to go to a doctor afterwards, was diagnosed as scabies, and the external embodiment of the invention 2 liquid medicine are smeared, i.e. recovery from illness after 4 days, and follow up a case by regular visits to and do not see recurrence so far.
Case 5 Lee, man, 48 years old.Go to a doctor in May, 2008.Two finger seams, wrist are bent side, the fossa cubitalis, waist, hypogastric region, external genitalia all pimple, little big as the needle point or the grain of rice, with night pruritus for very, the course of disease is half a year, is diagnosed as scabies.The external embodiment of the invention 3 liquid medicine just were clearly better in 3 days, just fully recovered after seven days, after consolidate to use a week again, pay a return visit and do not see recurrence so far.
In conjunction with above-mentioned pharmacology analysis, clinical experiment and model case as can be known, Chinese medicine composition of the present invention directly is applied to the affected part, through sick institute, determined curative effect, be difficult for recurrence with the back, also very simple, the easy row of preparation method all has significant curative effect to tinea pedis and scabies, the effective percentage of treatment tinea pedis is 93.3%, and the effective percentage of treatment scabies is 90.2%.
The specific embodiment
Below with specific embodiment the present invention is described in further detail, but protection scope of the present invention is not limited thereto:
Embodiment 1
Take by weighing following crude drugs: Cortex Pseudolaricis 3g, sulfur 3g, Calomelas 1g, Camphora 1g, Radix Sophorae Flavescentis 3g, Pericarpium Zanthoxyli 1g.Above Six-element medicine is ground to the powder altogether to 80 orders, add medical alcohol 200ml, soaked 2 days, get its soak and promptly get lotion.
Embodiment 2
Take by weighing following crude drugs: Cortex Pseudolaricis 5g, sulfur 4g, Calomelas 1.3g, Camphora 2g, Radix Sophorae Flavescentis 4g, Pericarpium Zanthoxyli 2g.Above Six-element medicine is ground to the powder altogether to 85 orders, add medical alcohol 250ml, soaked 3 days, get its soak and promptly get lotion.
Embodiment 3
Take by weighing following crude drugs: Cortex Pseudolaricis 10g, sulfur 6g, Calomelas 2g, Camphora 4g, Radix Sophorae Flavescentis 8g, Pericarpium Zanthoxyli 6g.Above Six-element medicine is ground to the powder altogether to 90 orders, add medical alcohol 300ml, soaked 4 days, get its soak and promptly get lotion.
Embodiment 4
Take by weighing following crude drugs: Cortex Pseudolaricis 15g, sulfur 9g, Calomelas 3g, Camphora 6g, Radix Sophorae Flavescentis 15g, Pericarpium Zanthoxyli 9g.Above Six-element medicine is ground to the powder altogether to 100 orders, add medical alcohol 500ml, soaked 7 days, get its soak and promptly get lotion.
Embodiment 5
Take by weighing following crude drugs: Cortex Pseudolaricis 3g, sulfur 3g, Calomelas 1g, Camphora 1g, Radix Sophorae Flavescentis 3g, Pericarpium Zanthoxyli 1g, calcined Alumen 3g, Realgar 3g, Radix Stemonae 3g, Semen Hydnocarpi 3g.Above ten flavor medicines are ground to the powder altogether to 80 orders, add medical alcohol 200ml, soaked 2 days, get its soak and promptly get lotion.
Embodiment 6
Take by weighing following crude drugs: Cortex Pseudolaricis 7g, sulfur 5g, Calomelas 1.5g, Camphora 3g, Radix Sophorae Flavescentis 6g, Pericarpium Zanthoxyli 6g, calcined Alumen 5g, Realgar 4g, Radix Stemonae 7g, Semen Hydnocarpi 4g.Above ten flavor medicines are ground to the powder altogether to 88 orders, add medical alcohol 320ml, soaked 3 days, get its soak and promptly get lotion.
Embodiment 7
Take by weighing following crude drugs: Cortex Pseudolaricis 12g, sulfur 8g, Calomelas 2.5g, Camphora 5g, Radix Sophorae Flavescentis 10g, Pericarpium Zanthoxyli 4g, calcined Alumen 7g, Realgar 6g, Radix Stemonae 12g, Semen Hydnocarpi 8g.Above ten flavor medicines are ground to the powder altogether to 95 orders, add medical alcohol 400ml, soaked 5 days, get its soak and promptly get lotion.
Embodiment 8
Take by weighing following crude drugs: Cortex Pseudolaricis 15g, sulfur 9g, Calomelas 3g, Camphora 6g, Radix Sophorae Flavescentis 15g, Pericarpium Zanthoxyli 9g, calcined Alumen 9g, Realgar 9g, Radix Stemonae 15g, Semen Hydnocarpi 9g.Above ten flavor medicines are ground to the powder altogether to 100 orders, add medical alcohol 500ml, soaked 7 days, get its soak and promptly get lotion.
Claims (4)
1. a Chinese medicine composition for the treatment of tinea pedis, scabies is characterized in that mainly being made by each crude drug of following weight proportioning: Cortex Pseudolaricis 3～15g, sulfur 3～9g, Calomelas 1～3g, Camphora 1～6g, Radix Sophorae Flavescentis 3～15g, Pericarpium Zanthoxyli 1～9g.
2. the Chinese medicine composition of treatment tinea pedis as claimed in claim 1, scabies is characterized in that: be added with calcined Alumen 3～9g, Realgar 3～9g, the Radix Stemonae 3～15g, Semen Hydnocarpi 3～9g in the described compositions.
3. preparation method for the treatment of the Chinese medicine composition of tinea pedis, scabies is characterized in that described method carries out according to the following steps:
(1) in by weight/volume, take by weighing Cortex Pseudolaricis 3～15g, sulfur 3～9g, Calomelas 1～3g, Camphora 1～6g, Radix Sophorae Flavescentis 3～1 5g, Pericarpium Zanthoxyli 1～9g, medical alcohol 200～500ml, standby;
(2) the Six-element crude drug of step (1) is ground to the powder altogether after, add medical alcohol and soaked 2～7 days, get its soak and promptly get lotion.
4. the preparation method of the Chinese medicine composition of treatment tinea pedis as claimed in claim 3, scabies, it is characterized in that: in the step (1), on the basis of Cortex Pseudolaricis, sulfur, Calomelas, Camphora, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli Six-element crude drug, add having taken by weighing calcined Alumen 3～9g, Realgar 3～9g, the Radix Stemonae 3～15g, Semen Hydnocarpi 3～9g in addition; In the step (2), with step (1) ten the flavor crude drug grind to the powder altogether.
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| CN2009100654828A CN101601768B (en) | 2009-07-21 | 2009-07-21 | Chinese medicinal composition for treating tinea pedis and scabies and preparation method thereof |
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| CN2009100654828A CN101601768B (en) | 2009-07-21 | 2009-07-21 | Chinese medicinal composition for treating tinea pedis and scabies and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103040929A (en) * | 2012-12-26 | 2013-04-17 | 上海市中医医院 | Traditional Chinese medicine composition for treating chronic eczema, dermatitis and keratoderma, and use of same |
| CN103191273A (en) * | 2013-03-31 | 2013-07-10 | 张秀兰 | Medicine for treating scabies and preparation method thereof |
| CN103784679A (en) * | 2014-03-06 | 2014-05-14 | 代忠 | Externally-applied drug for treating skin ringworm |
| CN105125699A (en) * | 2014-05-28 | 2015-12-09 | 陶育照 | Beriberi treatment method |
-
2009
- 2009-07-21 CN CN2009100654828A patent/CN101601768B/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103040929A (en) * | 2012-12-26 | 2013-04-17 | 上海市中医医院 | Traditional Chinese medicine composition for treating chronic eczema, dermatitis and keratoderma, and use of same |
| CN103191273A (en) * | 2013-03-31 | 2013-07-10 | 张秀兰 | Medicine for treating scabies and preparation method thereof |
| CN103784679A (en) * | 2014-03-06 | 2014-05-14 | 代忠 | Externally-applied drug for treating skin ringworm |
| CN105125699A (en) * | 2014-05-28 | 2015-12-09 | 陶育照 | Beriberi treatment method |
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| CN101601768B (en) | 2012-01-11 |
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