CN101600703A - 二螺四噁烷化合物及其在治疗疟疾和/或癌症中的应用 - Google Patents

二螺四噁烷化合物及其在治疗疟疾和/或癌症中的应用 Download PDF

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Publication number
CN101600703A
CN101600703A CNA2007800440866A CN200780044086A CN101600703A CN 101600703 A CN101600703 A CN 101600703A CN A2007800440866 A CNA2007800440866 A CN A2007800440866A CN 200780044086 A CN200780044086 A CN 200780044086A CN 101600703 A CN101600703 A CN 101600703A
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China
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compound
unsubstituted
replacement
cdcl
group
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Pending
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CNA2007800440866A
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English (en)
Chinese (zh)
Inventor
理查德·阿梅乌
保罗·迈克尔·奥内尔
安德鲁·斯塔胡尔斯基
杰马·埃利斯
斯蒂芬·安德鲁·沃德
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Liverpool School of Tropical Medicine
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Liverpool School of Tropical Medicine
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Application filed by Liverpool School of Tropical Medicine filed Critical Liverpool School of Tropical Medicine
Publication of CN101600703A publication Critical patent/CN101600703A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
    • C07D323/04—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNA2007800440866A 2006-09-30 2007-10-01 二螺四噁烷化合物及其在治疗疟疾和/或癌症中的应用 Pending CN101600703A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0619333.8A GB0619333D0 (en) 2006-09-30 2006-09-30 Dispiro tetraoxane compounds
GB0619333.8 2006-09-30

Publications (1)

Publication Number Publication Date
CN101600703A true CN101600703A (zh) 2009-12-09

Family

ID=37434997

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800440866A Pending CN101600703A (zh) 2006-09-30 2007-10-01 二螺四噁烷化合物及其在治疗疟疾和/或癌症中的应用

Country Status (7)

Country Link
US (2) US20100113436A1 (enExample)
EP (2) EP2091935A2 (enExample)
JP (1) JP2010505759A (enExample)
CN (1) CN101600703A (enExample)
CA (1) CA2665339A1 (enExample)
GB (1) GB0619333D0 (enExample)
WO (1) WO2008038030A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110452212A (zh) * 2019-07-30 2019-11-15 浙江大学 一种11-十一内酯类化合物和己内酯类化合物的制备方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0904935D0 (en) 2009-03-23 2009-05-06 Liverpool School Tropical Medicine Dispiro tetraoxane compounds
US9975854B2 (en) 2014-05-06 2018-05-22 Purdue Pharma L.P. Benzomorphan analogs and use thereof
WO2020240266A1 (en) 2019-05-31 2020-12-03 Ccmar - Centro De Ciências Do Mar Universidade Do Algarve New endoperoxide compounds, process for obtaining them and uses thereof for control of perkinsiosis in bivalves
US20240101584A1 (en) * 2021-02-01 2024-03-28 Westlake University Targeted delivery of 1,2,4,5 tetraoxane compounds and their uses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2901892A (en) * 1991-10-04 1993-05-03 Board Of Regents Of The University Of Nebraska, The Novel antimalarial peroxides and processes for their production and use
US6486199B1 (en) * 2001-06-21 2002-11-26 Medicines For Malaria Venture Mmv International Centre Cointrin Spiro and dispiro 1,2,4-trioxolane antimalarials
US6906098B2 (en) * 2002-02-09 2005-06-14 The United States Of America As Represented By The Secretary Of The Army Mixed steroidal 1,2,4,5-tetraoxane compounds and methods of making and using thereof
US6906205B2 (en) * 2002-06-21 2005-06-14 Medicines For Malaria Venture Mmv Spiro and dispiro 1,2,4-trioxolane antimalarials

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110452212A (zh) * 2019-07-30 2019-11-15 浙江大学 一种11-十一内酯类化合物和己内酯类化合物的制备方法
CN110452212B (zh) * 2019-07-30 2020-08-14 浙江大学 一种11-十一内酯类化合物和己内酯类化合物的制备方法

Also Published As

Publication number Publication date
EP2233479A1 (en) 2010-09-29
US20130023551A1 (en) 2013-01-24
GB0619333D0 (en) 2006-11-08
US20100113436A1 (en) 2010-05-06
JP2010505759A (ja) 2010-02-25
EP2091935A2 (en) 2009-08-26
WO2008038030A2 (en) 2008-04-03
CA2665339A1 (en) 2008-04-03
WO2008038030A3 (en) 2008-05-15

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Application publication date: 20091209