CN101574407B - Drug for preventing cold and preparation method thereof - Google Patents
Drug for preventing cold and preparation method thereof Download PDFInfo
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- CN101574407B CN101574407B CN2009100652589A CN200910065258A CN101574407B CN 101574407 B CN101574407 B CN 101574407B CN 2009100652589 A CN2009100652589 A CN 2009100652589A CN 200910065258 A CN200910065258 A CN 200910065258A CN 101574407 B CN101574407 B CN 101574407B
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Abstract
The invention relates to a drug for preventing cold and a preparation method thereof and belongs to the technical field of drugs. The preparation method includes the steps of: selecting and matching 9-11g of radix astragali, 9-10g of radix codonopsitis, 11-13g of honeysuckle, 10-13g of forsythia, 11-13g of radix isatidis, 10-13g of cyrtomium rhizome, 6-9g of rhubarb, 9-12g of radix scutellariae, 6-8g of bighead atractylodes rhizome and 5-6g of honey-fried licorice root according to certain amount, adding 800ml of water, decocting the mixed solution to 300-400ml, and finally making the mixed solution into a required dosage form. The drug is fully made from pure Chinese medicine materials, can relieve the pains of patients to great extent and generate no toxic or side effect, can reduce the medical expense for patients and have notable curing effect. The preparation method is simple and convenient. Besides, the drug is easy for the acceptance of patients and can be used for preventing cold as well as influenza.
Description
Technical field:
The present invention relates to medicine of a kind of preventing cold and preparation method thereof, belong to technical field of medicaments.
Background technology:
At present, the prevention method that hospital uses mainly is that the medicine with globulin, influenza vaccines or antibiotic and so on prevents and treat flu, these conventional therapys can make the generation of patient with the complication symptom in prevention or therapeutic process, increased patient's misery, these methods can lose the curative effect of expection for the flu (influenza) that is caused by new variant viral bacterial strain in addition.
Summary of the invention:
The medicine that the purpose of this invention is to provide a kind of preventing cold with reduction patient's misery, and avoids producing toxic and side effects, reduces patient's medical expense.
Technical scheme provided by the invention is:
Chinese medicine ingredients of the present invention comprises: the Radix Astragali, Radix Codonopsis, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Rhizoma Osmundae, Radix Scutellariae, Radix Et Rhizoma Rhei, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata Chinese crude drug.Wherein the weight proportion relation of each Chinese medicine ingredients is: Radix Astragali 9g-11g, Radix Codonopsis 9g-10g, Flos Lonicerae 11g-13g, Fructus Forsythiae 10g-13g, Radix Isatidis 11g-13g, Rhizoma Osmundae 10g-13g, Radix Et Rhizoma Rhei 6g-9g, Radix Scutellariae 9g-12g, Rhizoma Atractylodis Macrocephalae 6g-8g, Radix Glycyrrhizae Preparata 5g-6g.Specifically, it is by Radix Astragali 10g, Radix Codonopsis 9g, Flos Lonicerae 12g, Fructus Forsythiae 12g, and Radix Isatidis 12g, Rhizoma Osmundae 12g, Radix Et Rhizoma Rhei 6g, Radix Scutellariae 9g, Rhizoma Atractylodis Macrocephalae 6g, Radix Glycyrrhizae Preparata 5g is made.Medicine of the present invention is a liquid preparation, as: oral liquid, decoction, injection.The preparation method of the medicine of this preventing cold, get Radix Astragali 9g-11g, Radix Codonopsis 9g-10g, Flos Lonicerae 11g-13g, Fructus Forsythiae 10g-13g, Radix Isatidis 11g-13g, Rhizoma Osmundae 10g-13g, Radix Et Rhizoma Rhei 6g-9g, Radix Scutellariae 9g-12g, Rhizoma Atractylodis Macrocephalae 6g-8g, Radix Glycyrrhizae Preparata 5g-6g, above medicine is joined by measuring, add 800ml water, fry in shallow oil to 300-400ml, be made into the dosage form that needs then.Specifically, get Radix Astragali 10g, Radix Codonopsis 9g, Flos Lonicerae 12g, Fructus Forsythiae 12g, Radix Isatidis 12g, Rhizoma Osmundae 12g, Radix Et Rhizoma Rhei 6g, Radix Scutellariae 9g, Rhizoma Atractylodis Macrocephalae 6g, Radix Glycyrrhizae Preparata 5g, above medicine is joined by measuring, and adds 800ml water, fries in shallow oil to 300-400ml, is made into decoction then.
The present invention adopts pure Chinese medicine medical material to make fully, can alleviate patient's misery by a relatively large margin, avoids the toxic and side effects that the patient is produced by globulin or antibiotic and so on medicine.Because the relative Western medicine of price of composition medical material of the present invention is cheap, can reduce patient's medical expense like this.In addition, curative effect of the present invention is obvious, and preparation method is easy, is easily accepted by the patient, can be used for preventing cold and influenza.
Clinical Practice proves, uses the present invention to prevent the various flu effective percentage that caused by virus to reach 100%.
The specific embodiment
The present invention is made up of the Radix Astragali, Radix Codonopsis, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Rhizoma Osmundae, Radix Scutellariae, Radix Et Rhizoma Rhei, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata Chinese crude drug.
The gas of the Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae invigorating middle warmer unit, consolidating superficial resistance and battalion, but inducement interferon have the excitating organism vigor, and the enhancing human body immunity ability can stimulate macrophage phagocytic function.Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Rhizoma Osmundae are to multiple virus system of all facing upward and lethal effect.Radix Et Rhizoma Rhei, Radix Scutellariae, the Rhizoma Atractylodis Macrocephalae can the human body immunity improving abilities, and the function of dispelling pathogen in the interior catharsis is arranged again, can also microcirculation improvement, promote growth, proliferation and differentiation, maturation and the release of versatile stem cell, activate the body vigor, produce the opsonin of self, so energy is disease controlling rapidly, reach the purpose of prevention.
The present invention can adopt following component to be configured: Radix Astragali 10g, Radix Codonopsis 9g, Flos Lonicerae 12g, Fructus Forsythiae 12g, Radix Isatidis 12g, Rhizoma Osmundae 12g, Radix Et Rhizoma Rhei 6g, Radix Scutellariae 9g, Rhizoma Atractylodis Macrocephalae 6g, Radix Glycyrrhizae Preparata 5g.More than each medical material join by measuring, add 800ml water, can be oral when decocting to 300-400ml.One day twice, course of treatment of first quarter moon.
Observe 260 routine patients, wherein outpatient service 234 examples, 26 examples of being in hospital, more than all meet the standard of " weakness type cold " that " disease of tcm diagnosis criterion of therapeutical effect " divide apoplexy due to endogenous wind about the diagnosis basis and the disease of flu.Be categorized as treatment immediately according to the recurrent respiratory tract infection diagnosis that in April, 1987, whole nation infantile respiratory disease meeting was formulated and organize 130 examples, matched group 130 examples.Male's 67 examples in the treatment group, women's 63 examples, age bracket is 6-76 year, the mean age is 38 years old.The course of disease is the shortest to be 15 months, and the longest is 32 years, average out to 6.5 years.Matched group male 66 examples, women's 64 examples, age bracket is 8-73 year, the mean age is 36 years old.The course of disease is the shortest to be 1 month, and the longest is 30 years, average out to 6.3 years.Two groups of general clinical datas have significant difference.
Curative effect determinate standard: show the school, take medicine and upper respiratory tract infection does not take place in back 3 years or the morbidity number of times obviously reduces; Take a turn for the better, all right person of the slight medication of symptom, slight respiratory tract infection or morbidity number of times obviously reduce, and the course of disease obviously shortens; Invalid, the respiratory tract infection number of times does not subtract, and the course of disease, symptom do not have obvious improvement.
Concrete therapeutic outcome sees the following form:
The treatment group:
The sick kind | Case | Produce effects | Take a turn for the better | Invalid |
Easy catching a cold | 130? | 123? | 7? | 0? |
Matched group:
The sick kind | Case | Produce effects | Take a turn for the better | Invalid |
Easy catching a cold | 130? | 40? | 32? | 58? |
Two groups of ratios have significant difference.
Patient woman, 53 years old, surplus the easy catching a cold ten year, Changes in weather was easily caught a cold whenever.Once examined in certain hospital and be " allergic rhinitis ", and with surplus the coronary disease medical history ten year.The time and have in the heart and feel oppressed and work property cardiopalmus.Recently because of tired sx, behind examination in hospital, intend examining being coronary heart disease, ventricular premature contraction is with chamber speed, inscribe that symptom sees that cold extremities with aversion to cold, sneeze play that continuous cropping, clear water nasal mucus, twang weigh, lie awake all night morning, purple lip, light red tongue are fat, thready pulse and all diseases such as number are closed ginseng, card belongs to weakness of the spleen and stomach, edema due to YANG-insufficiency, stagnation of heart-blood, the mind is lost peaceful.Control with QI invigorating warming YANG, activating blood and eliminatng dampness, mind tranquilizing and the heart calming, strengthening the spleen and stomach.Prescription is got the strong heart soup of allaying excitement, and is decocted in water for oral dose day potion, clothes sooner or later.The ligustrazine pin use in transfusion, stings five first pins, Radix Salviae Miltiorrhizae Injection, astragalus needle, once a day, cardiopalmus after 7 days, feel oppressed, symptom such as fear of cold obviously alleviates the 5-6h that can fall asleep every night, all symptom improvements.Continue to take the strong heart soup of allaying excitement and join medicine of the present invention.Visit during this time in January, 2009, flu is sent out less or light symptoms is only arranged, and few little medication can recover.Coronary heart disease does not have recurrence is arranged.
Patient woman, 13 years old, the leukemia medical history.Take a turn for the better after the hospitalize of Beijing, family recuperates now.Patient body puffiness due to deficiency, a flu must be infused in hospital.It is its treatment that family numbers of patients adopts prescription of the present invention, take several courses of treatment after patient's body immunity obviously improve.When once catching a cold later on can fully recover in oral twice YINQIAO sheet and amoxicillin.Visited 1 year, this patient does not catch a cold one year.
The patient man, 56 years old, whenever to season in spring and autumn, easily to catch a cold when Changes in weather is frequent for many years, annual ill number of times is nearly more than 20 times.Inscribing patient's symptom is to play sneeze continuous cropping, hoarseness, the clear nasal mucus of stream morning, have a stuffy nose low voice speaking, headache, general malaise, have no temperature, extremity are not warm, anorexia is weak, a little less than the lustreless complexion, light red tongue, deep-thready pulse, once repeatedly took various coldrexs or quiet high-grade liquid, and controlled repeatly and do not heal.Passages through which vital energy circulates disease is referred and synthesized, and distinguishes to be weakness of the spleen and stomach, and lung qi loses empty, and clear key is unfavorable, and yang deficiency is this, and affection of exogenous wind-cold is a mark.The method that gives strengthening the spleen and stomach, lung benefiting gas, dispersing wind and cold cures mainly, five doses of throwing sides, and the state of an illness takes a turn for the better to some extent.Still throw the place ahead and join prescription of the present invention with consolidation, during get better every day.Visited 6 years, patient's body constitution is fine always, and rare uncomfortable medication is promptly healed.
Claims (6)
1. the medicine of a preventing cold, it is characterized in that: it is made by the following weight proportion raw material: Radix Astragali 9g-11g, Radix Codonopsis 9g-10g, Flos Lonicerae 11g-13g, Fructus Forsythiae 10g-13g, Radix Isatidis 11g-13g, Rhizoma Osmundae 10g-13g, Radix Et Rhizoma Rhei 6g-9g, Radix Scutellariae 9g-12g, Rhizoma Atractylodis Macrocephalae 6g-8g, Radix Glycyrrhizae Preparata 5g-6g.
2. the medicine of a kind of preventing cold according to claim 1, it is characterized in that: wherein the weight proportion of each raw material is: Radix Astragali 10g, Radix Codonopsis 9g, Flos Lonicerae 12g, Fructus Forsythiae 12g, Radix Isatidis 12g, Rhizoma Osmundae 12g, Radix Et Rhizoma Rhei 6g, Radix Scutellariae 9g, Rhizoma Atractylodis Macrocephalae 6g, Radix Glycyrrhizae Preparata 5g.
3. the medicine of a kind of preventing cold according to claim 1 and 2, it is characterized in that: described medicine is a liquid preparation.
4. the medicine of a kind of preventing cold according to claim 3 is characterized in that described medicine is injection or decoction.
5. the preparation method of the medicine of a preventing cold, it is characterized in that: get Radix Astragali 9g-11g, Radix Codonopsis 9g-10g, Flos Lonicerae 11g-13g, Fructus Forsythiae 10g-13g, Radix Isatidis 11g-13g, Rhizoma Osmundae 10g-13g, Radix Et Rhizoma Rhei 6g-9g, Radix Scutellariae 9g-12g, Rhizoma Atractylodis Macrocephalae 6g-8g, Radix Glycyrrhizae Preparata 5g-6g, above medicine is joined by measuring, add 800ml water, fry in shallow oil to 300-400ml, be made into the dosage form that needs then.
6. the preparation method of the medicine of a kind of preventing cold according to claim 5 is characterized in that: get Radix Astragali 10g, Radix Codonopsis 9g, Flos Lonicerae 12g, Fructus Forsythiae 12g, Radix Isatidis 12g, Rhizoma Osmundae 12g, Radix Et Rhizoma Rhei 6g, Radix Scutellariae 9g, Rhizoma Atractylodis Macrocephalae 6g, Radix Glycyrrhizae Preparata 5g, above medicine is joined by measuring, and adds 800ml water, fry in shallow oil to 300-400ml, be made into decoction then.
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101961396A (en) * | 2010-10-26 | 2011-02-02 | 山西省长治精神病院 | Medicament for preventing and treating influenza |
CN102119967A (en) * | 2010-12-21 | 2011-07-13 | 肖泽林 | Medicament for preventing respiratory infectious disease |
CN103169862A (en) * | 2012-12-12 | 2013-06-26 | 延安市职业技术学院 | Traditional Chinese medicine formula for treating vital myocarditis |
CN104173713A (en) * | 2014-09-12 | 2014-12-03 | 钟召凤 | Medicine composition for preventing infantile viral fever and preparation method thereof |
CN104623106A (en) * | 2015-02-04 | 2015-05-20 | 郝立娟 | Medicine for treating cold |
CN111249390A (en) * | 2020-03-12 | 2020-06-09 | 尧舜泽生物医药(南京)有限公司 | Forsythia-astragalus root compound preparation and preparation method and application thereof |
CN111467465A (en) * | 2020-05-08 | 2020-07-31 | 熊德山 | Heat-clearing composition and preparation process thereof |
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CN1698674A (en) * | 2004-05-21 | 2005-11-23 | 吴占亨 | Double resistant oral liquid |
CN1682843A (en) * | 2005-03-15 | 2005-10-19 | 华南农业大学 | Chinese medicine composition for preventing bird flu |
CN101023997A (en) * | 2007-03-28 | 2007-08-29 | 东北农业大学 | Anti-fowl-plague Chinese medicine and preparing method |
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