CN101571543A - Magnetic nanometer immunochromatography card reading device - Google Patents

Magnetic nanometer immunochromatography card reading device Download PDF

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Publication number
CN101571543A
CN101571543A CNA2009100264812A CN200910026481A CN101571543A CN 101571543 A CN101571543 A CN 101571543A CN A2009100264812 A CNA2009100264812 A CN A2009100264812A CN 200910026481 A CN200910026481 A CN 200910026481A CN 101571543 A CN101571543 A CN 101571543A
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CN
China
Prior art keywords
magnetic
card
read
immunochromatography
signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2009100264812A
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Chinese (zh)
Inventor
杨静华
吴斌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WUXI NASHENG BIOTECHNOLOGY CO Ltd
Original Assignee
WUXI NASHENG BIOTECHNOLOGY CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WUXI NASHENG BIOTECHNOLOGY CO Ltd filed Critical WUXI NASHENG BIOTECHNOLOGY CO Ltd
Priority to CNA2009100264812A priority Critical patent/CN101571543A/en
Publication of CN101571543A publication Critical patent/CN101571543A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a magnetic nanometer immunochromatography card reading device, which belongs to the technical field of immunoassay. The device comprises a magnetic reader host machine and a magnetic reader special immunochromatography card, wherein the magnetic reader host machine comprises a card holding bin for loading the magnetic reader special immunochromatography card, chutes allowing the card holding bin to slide left and right, a driving motor and a driving belt which drive the card holding bin to slide, a magnetizing magnetic head for magnetizing magnetic nanometer microspheres, a reproduce head for reading magnetic signals, a signal conversion device for converting the magnetic signals, and a signal output device for outputting signals and a base plate for fixing the parts. During operation, magnetic nanometer microspheres are magnetized by the magnetizing magnetic head, the reproduce head reads data, the signal intensity of the magnetic signals on the immunochromatography detection card are visually displayed through the signal conversion device and the signal output device so as to quantitatively detect an object to be detected. The device has the advantages of simple structure, convenient operation, high precision and the like, and is used for scientific researches on medical and environmental detection and the like, and fills a market gap.

Description

A kind of magnetic nanometer immunochromatographycard card reading device
Technical field
A kind of magnetic nanometer immunochromatographycard card reading device relates to a kind of magnetic signal reading device, a kind of specifically reading device that can read magnetic Nano microsphere magnetic signal power on the magnetic Nano immunochromatography card.Belong to the immuno analytical method field.
Background technology
Magnetic Nano microsphere has had very widely aspect biological and medical to be used, for example purifying, cell separation and pharmaceutical carrier of fixing, the immunoassay of protein and enzyme, RNA and DNA or the like.Utilize magnetic Nano microsphere as a token of the carrier of thing carry out immunoassay have the precision height, simple to operate, can be quantitative etc. advantage.At present, the utilization of magnetic Nano microsphere more and more widely.
Have the characteristic that can be detected by magnetic signal detection device based on magnetic Nano microsphere, the spy designs a kind of device that can make things convenient for magnetic Nano microsphere magnetic signal on the reading immunity-chromatography test card.The present invention can be magnetized magnetic Nano microsphere by the magnetization magnetic head, utilize the playback head reading of data again, magnetic signal can demonstrate the power of magnetic signal on the immunochromatographydetection detection card intuitively by chromacoder and signal output apparatus, thereby can reach the purpose to thing detection by quantitative to be checked.
Therefore, design the device of magnetic Nano microsphere magnetic signal on a kind of test card of reading immunity-chromatography easily,, remedy the vacancy in market to make things convenient for the research needs of scientific research industries such as medical science, environment measuring.
Summary of the invention
The purpose of this invention is to provide a kind of magnetic nanometer immunochromatographycard card reading device, the signal of magnetic Nano microsphere magnetic on the reading immunity-chromatography test card to make things convenient for the research needs of scientific research industries such as medical science, environment measuring, remedies the vacancy in market easily.
Technical scheme of the present invention: a kind of magnetic nanometer immunochromatographycard card reading device comprises: a, magnetic are read instrument main body machine and b, magnetic is read instrument special immune chromatography card two parts;
Magnetic is read instrument main body machine, comprises being used to carry signal output apparatus 8 and the fixing chassis 9 with upper-part that magnetic is read the slide glass storehouse 1 of instrument special immune chromatography card, is used to the sliding tray 2 that the slide glass storehouse can be horizontally slipped, the chromacoder 7 that drives driving motor 3 and driving belt 4 thereof, the magnetization magnetic head 5 that is used for the magnetized magnetic Nano microsphere that slides in the slide glass storehouse, the playback head 6 that is used to read magnetic signal, conversion magnetic signal, output signal.
Magnetic is read instrument special immune chromatography card, comprise application of sample pad 10, nitrocellulose filter 11, the adsorptive pads 12 that adds testing sample and cover on the nitrocellulose filter, between application of sample pad and adsorptive pads part, be used to prevent the PVC plastic sheeting 13 that magnetic bead is walked by strong magnetic, on nitrocellulose filter, scribble detection line 16 and control line 17, application of sample pad, nitrocellulose filter and adsorptive pads stick on the PVC liner plate, and PVC shell 14 is housed on the immunochromatography card, have well 15 on shell, the well position is corresponding with the application of sample pad.
Principle of work of the present invention is as follows:
During work analyte sample fluid is splashed into magnetic and read instrument special immune chromatography card well, leave standstill after 5 minutes the chromatography card is put into the slide glass storehouse, starter motor, left and right sides to-and-fro movement can be done in the slide glass storehouse under the traction of driving belt, magnetic head begins to read magnetic signal simultaneously, signal, and is exported by signal output apparatus to chromacoder through circuit transmission.
Beneficial effect of the present invention: by above disclosed technical scheme as can be known, simple in structure, easy to operate, degree of accuracy advantages of higher that the present invention has.
Description of drawings
Fig. 1 magnetic nanometer immunochromatographycard card reading device synoptic diagram.
A, magnetic are read instrument main body machine and b, magnetic is read instrument special immune chromatography card; 1, slide glass storehouse, 2, sliding tray, 3, driving motor, 4, driving belt, 5, the magnetization magnetic head, 6, playback head, 7, chromacoder, 8, signal output apparatus, 9, the chassis.
Fig. 2 magnetic is read vertical view, the front elevation of instrument special immune chromatography card.10, application of sample pad, 11, nitrocellulose filter, 12, adsorptive pads, 13, the PVC plastic sheeting, 16, detection line, 17, control line, 14, the PVC shell, 15, well.
The follow-on magnetic nanometer immunochromatographycard card reading device synoptic diagram of Fig. 3.1, slide glass storehouse, 2, sliding tray, 5, the magnetization magnetic head, 6, playback head, 18, pushbutton switch, 19, LCDs, 20, the PVC shell.
Embodiment
Embodiment 1
Referring to Fig. 1, magnetic nanometer immunochromatographycard card reading device of the present invention comprises that magnetic is read instrument main body machine and magnetic is read instrument special immune chromatography card two large divisions.
Magnetic is read instrument main body machine and is comprised that being used to carry magnetic reads the slide glass storehouse of instrument special immune chromatography card, is used to the sliding tray that the slide glass storehouse can be horizontally slipped, the signal output apparatus that drives driving motor and driving belt thereof, the magnetization magnetic head that is used for magnetized beads that slides in the slide glass storehouse, the playback head that is used to read magnetic signal, the chromacoder of changing magnetic signal, output signal and fixing chassis with upper-part.
Referring to Fig. 2, magnetic is read instrument special immune chromatography card and is comprised application of sample pad, NC film, the adsorptive pads that adds testing sample and cover (part between application of sample pad and the adsorptive pads) on the NC film and be used to the PVC plastic sheeting that prevents that magnetic bead from being siphoned away by magnetic head.
Described shell can be rectangular parallelepiped, right cylinder and other shapes.
Embodiment 2
As a further improvement on the present invention, on the basis of Fig. 1, develop and easier, the magnetic nanometer immunochromatographycard card reading device of hommization more of operation, as shown in Figure 3.Read to add on the instrument main body machine at the magnetic of Fig. 1 and put a PVC shell, and LCDs and power switch button are placed in PVC shell outside; Sliding tray and slide glass storehouse change inserted combination (shown in Fig. 3 frame of broken lines) into, have so both strengthened the steadiness in slide glass storehouse, have increased the aesthetics of main body machine again.
The above only is preferred embodiment of the present invention, is not to be used for limiting the scope of the present invention.All equalizations of doing according to the scope of the invention change and modify, and are the present invention and contain.

Claims (1)

1, a kind of magnetic nanometer immunochromatographycard card reading device is characterized in that, comprises that magnetic is read instrument main body machine (a) and magnetic is read instrument special immune chromatography card (b) two parts;
Magnetic is read instrument main body machine (a), comprises being used to carry signal output apparatus (8) and the fixing chassis (9) with upper-part that magnetic is read the slide glass storehouse (1) of instrument special immune chromatography card, is used to the sliding tray (2) that the slide glass storehouse can be horizontally slipped, the chromacoder (7) that drives driving motor (3) and driving belt (4) thereof, the magnetization magnetic head (5) that is used for the magnetized magnetic Nano microsphere that slides in the slide glass storehouse, the playback head (6) that is used to read magnetic signal, conversion magnetic signal, output signal;
Magnetic is read instrument special immune chromatography card (b), comprise the application of sample pad (10) that adds testing sample, nitrocellulose filter (11), adsorptive pads (12) and covering on the nitrocellulose filter, part between application of sample pad and adsorptive pads, be used to prevent the PVC plastic sheeting (13) that magnetic bead is walked by strong magnetic, on nitrocellulose filter, scribble detection line (16) and control line (17), the application of sample pad, nitrocellulose filter and adsorptive pads stick on the PVC liner plate, and PVC shell (14) is housed on the immunochromatography card, have well (15) on shell, the well position is corresponding with the application of sample pad.
CNA2009100264812A 2009-04-24 2009-04-24 Magnetic nanometer immunochromatography card reading device Pending CN101571543A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA2009100264812A CN101571543A (en) 2009-04-24 2009-04-24 Magnetic nanometer immunochromatography card reading device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA2009100264812A CN101571543A (en) 2009-04-24 2009-04-24 Magnetic nanometer immunochromatography card reading device

Publications (1)

Publication Number Publication Date
CN101571543A true CN101571543A (en) 2009-11-04

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CNA2009100264812A Pending CN101571543A (en) 2009-04-24 2009-04-24 Magnetic nanometer immunochromatography card reading device

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CN (1) CN101571543A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104459098A (en) * 2013-09-23 2015-03-25 西门子医疗保健诊断公司 Diagnostic device for acquiring medical sample image
CN107703297A (en) * 2017-08-24 2018-02-16 苏州万纳生物科技有限公司 Weak magnetic signal detection means
CN110221061A (en) * 2019-06-21 2019-09-10 上海交通大学 It is a kind of for magnetic chromatography chip can self-positioning transmission device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104459098A (en) * 2013-09-23 2015-03-25 西门子医疗保健诊断公司 Diagnostic device for acquiring medical sample image
CN107703297A (en) * 2017-08-24 2018-02-16 苏州万纳生物科技有限公司 Weak magnetic signal detection means
CN110221061A (en) * 2019-06-21 2019-09-10 上海交通大学 It is a kind of for magnetic chromatography chip can self-positioning transmission device
CN110221061B (en) * 2019-06-21 2021-07-13 上海交通大学 Self-positioning transmission device for magnetic chromatography chip

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Application publication date: 20091104