CN101563097A - 用于组织损伤的干细胞生长因子疗法 - Google Patents
用于组织损伤的干细胞生长因子疗法 Download PDFInfo
- Publication number
- CN101563097A CN101563097A CNA2006800458460A CN200680045846A CN101563097A CN 101563097 A CN101563097 A CN 101563097A CN A2006800458460 A CNA2006800458460 A CN A2006800458460A CN 200680045846 A CN200680045846 A CN 200680045846A CN 101563097 A CN101563097 A CN 101563097A
- Authority
- CN
- China
- Prior art keywords
- scf
- nucleic acid
- cells
- cell
- transported
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73705805P | 2005-11-14 | 2005-11-14 | |
| US60/737,058 | 2005-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101563097A true CN101563097A (zh) | 2009-10-21 |
Family
ID=38049189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006800458460A Pending CN101563097A (zh) | 2005-11-14 | 2006-11-13 | 用于组织损伤的干细胞生长因子疗法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8404653B2 (https=) |
| EP (1) | EP1948246B1 (https=) |
| JP (1) | JP2009517343A (https=) |
| CN (1) | CN101563097A (https=) |
| AU (1) | AU2006315601A1 (https=) |
| CA (1) | CA2629775A1 (https=) |
| WO (1) | WO2007059010A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114450013A (zh) * | 2019-04-12 | 2022-05-06 | 爱莫里大学 | 用于促进造血细胞的细胞毒性的组合物和方法 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008118370A2 (en) * | 2007-03-22 | 2008-10-02 | The Trustees Of The University Of Pennsylvania | Hyperbaric treatment in wound healing |
| JP5467742B2 (ja) * | 2007-08-24 | 2014-04-09 | 国立大学法人 岡山大学 | Ecpを有効成分とする左室リモデリングの予防及び治療剤。 |
| GB0814302D0 (en) | 2008-08-05 | 2008-10-01 | Coretherapix Slu | Compounds and methods |
| DK2830662T3 (da) | 2012-03-29 | 2019-01-02 | Univ Columbia | Fremgangsmåder til behandlng af hårtabsforstyrrelser |
| US20150190532A1 (en) | 2012-04-04 | 2015-07-09 | The Trustees Of Columbia University In The City Of New York | Smooth muscle specific inhibition for anti-restenotic therapy |
| GB201400562D0 (en) | 2014-01-14 | 2014-03-05 | Orla Protein Technologies Ltd | Protein coated polymeric substrate |
| AU2016321298A1 (en) | 2015-09-09 | 2018-03-29 | The Trustees Of Columbia University In The City Of New York | Reduction of ER-MAM localized APP-C99 and methods of treating Alzheimer's Disease |
| US10188750B1 (en) | 2015-10-23 | 2019-01-29 | University Of South Florida | Self-replicating cell selective gene delivery compositions, methods, and uses thereof |
| WO2019200240A1 (en) * | 2018-04-13 | 2019-10-17 | Board Of Regents, The University Of Texas System | Transmembrane stem cell factor (tm-scf) lipid nanocarriers and methods of use thereof |
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| US3995631A (en) * | 1971-01-13 | 1976-12-07 | Alza Corporation | Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient |
| US3760984A (en) * | 1971-09-29 | 1973-09-25 | Alza Corp | Osmotically powered agent dispensing device with filling means |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US3923426A (en) | 1974-08-15 | 1975-12-02 | Alza Corp | Electroosmotic pump and fluid dispenser including same |
| US4036228A (en) * | 1975-09-11 | 1977-07-19 | Alza Corporation | Osmotic dispenser with gas generating means |
| US3987790A (en) * | 1975-10-01 | 1976-10-26 | Alza Corporation | Osmotically driven fluid dispenser |
| US4016880A (en) | 1976-03-04 | 1977-04-12 | Alza Corporation | Osmotically driven active agent dispenser |
| US4111202A (en) | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
| US4111203A (en) | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system with means for improving delivery kinetics of system |
| US4203442A (en) * | 1977-08-29 | 1980-05-20 | Alza Corporation | Device for delivering drug to a fluid environment |
| US4203440A (en) * | 1978-10-23 | 1980-05-20 | Alza Corporation | Device having variable volume chamber for dispensing useful agent |
| US4210139A (en) | 1979-01-17 | 1980-07-01 | Alza Corporation | Osmotic device with compartment for governing concentration of agent dispensed from device |
| US4360019A (en) | 1979-02-28 | 1982-11-23 | Andros Incorporated | Implantable infusion device |
| US4692147A (en) | 1980-04-02 | 1987-09-08 | Medtronic, Inc. | Drug administration device |
| US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4487603A (en) * | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
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| US4865845A (en) | 1986-03-21 | 1989-09-12 | Alza Corporation | Release rate adjustment of osmotic or diffusional delivery devices |
| US5387419A (en) * | 1988-03-31 | 1995-02-07 | The University Of Michigan | System for controlled release of antiarrhythmic agents |
| US5057318A (en) | 1988-12-13 | 1991-10-15 | Alza Corporation | Delivery system for beneficial agent over a broad range of rates |
| US5059423A (en) | 1988-12-13 | 1991-10-22 | Alza Corporation | Delivery system comprising biocompatible beneficial agent formulation |
| US5399493A (en) * | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
| US5437994A (en) * | 1989-06-15 | 1995-08-01 | Regents Of The University Of Michigan | Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
| US5112614A (en) | 1989-09-14 | 1992-05-12 | Alza Corporation | Implantable delivery dispenser |
| DK0423980T3 (da) * | 1989-10-16 | 2000-10-09 | Amgen Inc | Stamcellefaktor |
| US6759215B1 (en) * | 1989-10-16 | 2004-07-06 | Amgen Inc. | Method of preparing human stem cell factor polypeptide |
| US6326198B1 (en) * | 1990-06-14 | 2001-12-04 | Regents Of The University Of Michigan | Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
| US5234693A (en) * | 1990-07-11 | 1993-08-10 | Alza Corporation | Delivery device with a protective sleeve |
| US5234692A (en) * | 1990-07-11 | 1993-08-10 | Alza Corporation | Delivery device with a protective sleeve |
| US20030125519A1 (en) * | 1990-08-27 | 2003-07-03 | Peter Besmer | Ligand for the c-kit receptor and methods of use thereof |
| US5137727A (en) * | 1991-06-12 | 1992-08-11 | Alza Corporation | Delivery device providing beneficial agent stability |
| US5681278A (en) * | 1994-06-23 | 1997-10-28 | Cormedics Corp. | Coronary vasculature treatment method |
| US5827216A (en) * | 1995-06-07 | 1998-10-27 | Cormedics Corp. | Method and apparatus for accessing the pericardial space |
| US5797870A (en) * | 1995-06-07 | 1998-08-25 | Indiana University Foundation | Pericardial delivery of therapeutic and diagnostic agents |
| US5900433A (en) * | 1995-06-23 | 1999-05-04 | Cormedics Corp. | Vascular treatment method and apparatus |
| CA2230819C (en) * | 1995-08-29 | 2009-04-14 | Sumitomo Pharmaceuticals Co., Ltd. | Medicament comprising hgf gene |
| GB9519776D0 (en) * | 1995-09-28 | 1995-11-29 | Casimir Colin | Materials and methods relating to the transfer of nucleic acid into stem cells |
| WO1997016169A1 (en) | 1995-11-01 | 1997-05-09 | Chiron Corporation | Treatment of a cardiovascular indication by delivery of therapeutics to the pericardial space |
| NZ331186A (en) | 1996-02-02 | 2000-04-28 | Alza Corp | Osmotically driven sustained delivery drug delivery capsule |
| US6080728A (en) * | 1996-07-16 | 2000-06-27 | Mixson; A. James | Carrier: DNA complexes containing DNA encoding anti-angiogenic peptides and their use in gene therapy |
| CA2213906A1 (en) | 1996-09-23 | 1998-03-23 | Dusica Maysinger | Pharmaceutical composition and method for neuron rescue in ischemic stroke |
| US6258119B1 (en) | 1996-11-07 | 2001-07-10 | Myocardial Stents, Inc. | Implant device for trans myocardial revascularization |
| US5931810A (en) * | 1996-12-05 | 1999-08-03 | Comedicus Incorporated | Method for accessing the pericardial space |
| US6443949B2 (en) * | 1997-03-13 | 2002-09-03 | Biocardia, Inc. | Method of drug delivery to interstitial regions of the myocardium |
| DE69837491T2 (de) * | 1997-07-03 | 2008-01-17 | Osiris Therapeutics, Inc. | Menschliche mesenchymale stammzellen aus peripherem blut |
| US6093531A (en) * | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
| US6251418B1 (en) | 1997-12-18 | 2001-06-26 | C.R. Bard, Inc. | Systems and methods for local delivery of an agent |
| US7078387B1 (en) * | 1998-12-28 | 2006-07-18 | Arch Development Corp. | Efficient and stable in vivo gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors |
| US8075881B2 (en) * | 1999-08-05 | 2011-12-13 | Regents Of The University Of Minnesota | Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure |
| WO2002030443A2 (en) | 2000-10-11 | 2002-04-18 | The Wistar Institute | Regulation of human skin healing |
| EP1379197A4 (en) * | 2001-03-23 | 2009-06-03 | Durect Corp | DISPOSAL OF MEDICINAL PRODUCTS OF DELAYED RELEASE DEVICES IMPLANTED IN MYOKARD TISSUE OR PER ICARDROOM |
| US7605128B2 (en) * | 2002-02-14 | 2009-10-20 | Buck Institute For Age Research | Neurogenerative or neurotrophic factors for mitigating a symptom of ischemia |
| US20070238675A1 (en) * | 2003-08-11 | 2007-10-11 | Phillips M I | Stem Cell Beacon |
| WO2005053729A1 (en) | 2003-11-26 | 2005-06-16 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Stem cell factor for inducing neural stem cell migration to areas of neurological injury |
| WO2005082440A1 (en) | 2004-02-26 | 2005-09-09 | V-Kardia Pty Ltd | Isolating cardiac circulation |
| AU2005306894B2 (en) | 2004-11-05 | 2011-11-24 | Northwestern University | Use of SCF and G-CSF in the treatment of cerebral ischemia and neurological disorders |
-
2006
- 2006-11-13 CN CNA2006800458460A patent/CN101563097A/zh active Pending
- 2006-11-13 AU AU2006315601A patent/AU2006315601A1/en not_active Abandoned
- 2006-11-13 CA CA002629775A patent/CA2629775A1/en not_active Abandoned
- 2006-11-13 EP EP06827745.8A patent/EP1948246B1/en active Active
- 2006-11-13 WO PCT/US2006/043937 patent/WO2007059010A2/en not_active Ceased
- 2006-11-13 JP JP2008540240A patent/JP2009517343A/ja active Pending
- 2006-11-13 US US12/084,673 patent/US8404653B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114450013A (zh) * | 2019-04-12 | 2022-05-06 | 爱莫里大学 | 用于促进造血细胞的细胞毒性的组合物和方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090304636A1 (en) | 2009-12-10 |
| AU2006315601A1 (en) | 2007-05-24 |
| JP2009517343A (ja) | 2009-04-30 |
| US8404653B2 (en) | 2013-03-26 |
| EP1948246A2 (en) | 2008-07-30 |
| CA2629775A1 (en) | 2007-05-24 |
| WO2007059010A2 (en) | 2007-05-24 |
| EP1948246A4 (en) | 2010-04-28 |
| WO2007059010A3 (en) | 2009-04-30 |
| EP1948246B1 (en) | 2017-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20091021 |