CN101549120A - Traditional Chinese medicine composition for treating acne vulgaris and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating acne vulgaris and preparation method thereof Download PDFInfo
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- CN101549120A CN101549120A CNA2008101034226A CN200810103422A CN101549120A CN 101549120 A CN101549120 A CN 101549120A CN A2008101034226 A CNA2008101034226 A CN A2008101034226A CN 200810103422 A CN200810103422 A CN 200810103422A CN 101549120 A CN101549120 A CN 101549120A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating acne vulgaris. The traditional Chinese medicine composition is prepared by coix seed, honeysuckle flower, heartleaf houttuynia herb, parslane herb, mulberry leaf, coastal glehnia root, lancelesf lily bulb, common yam rhizome, peach seed, raw gypsum, motherwort herb, weeping forsythiae capsule, baical skullcap root, radix salviae miltiorrhizae, tangerine peel, common cnidium fruit, swordlike atractylodes rhizome, dahurian patrinia herb, root of sandhill tylophora, ginseng leaf and/or a pharmaceutically acceptable carrier. The invention further relates to a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the efficacies of clearing heat, removing toxin, removing phlegm, arresting cough, promoting blood circulation, removing blood stasis, eliminating inflammation and softening hard masses and is used for treating the acne vulgaris and the like caused by damp-heat in spleen and stomach, blood stasis, phlegm coagulation, lung heat and blood heat.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, specifically, relate to a kind of Chinese medicine composition for the treatment of acne and preparation method thereof.
Background technology
Acne (cuo chuang) is commonly called as comedo, acne, skin sore, is dermatology common disease, frequently-occurring disease.Add up according to scholars, the male has 95% in adolescence, and the women has 85% acne of suffering from various degree.So everybody is called " comedo " is very proper.Acne (comedo) is a kind of pilosebaceous chronic dermatosis that betides, and is mainly in women's head-ornaments portion, the position that sebaceous gland such as cervical region, shirtfront back are abundant.The main clinical manifestation of acne (comedo) is blackhead, hoary hair's acne, inflammatory pimple, pustule, tuberosity, cyst, easily forms pigmentation, corse sweat pore even the infringement of cicatrix sample.The influence beauty treatment, severe patient can cause disfeaturing, and causes great mental pressure and psychic pain to youngster.The early discovery of primary disease, early treatment are very important.In time the infringement of skin can be avoided or reduce to the diagnosis and treatment of standard.
The cause of disease of acne (comedo) is clear and definite, be to be infected by the anaerobic propionibacterium acnes to cause, but it is multifactorial disease.At first, endocrine in the body: mainly be that the androgen secretion level increases, impels sebum secretion to enliven, increase.It is key factor in the pathogenesis that the pilosebaceous unit opening gets clogged.Under the situation of hair follicle obturation, propionibacterium acnes is bred in a large number, causes inflammation, forms the most basic infringement inflammatory pimple of acne (comedo).In the pilosebaceous unit inside of obturation, a large amount of sebums, a large amount of pus cell form tuberosity, cyst and sebaceous cyst to the pilosebaceous unit structural deterioration, destroy skin at last even form cicatrix.Acne is sent out the age between 12～25 years old well, but also had just just send out in 10～13 years old or 30 years old.In addition, often long small pox also has the factor of genetic aspect, if parents have this class worry, sons and daughters also can inherit this body constitution.Acne often betides the many areas of sebaceous gland distribution such as face, shirtfront, back.
Acne generally has following four types:
1. blackhead (Black-head): oils and fats has stopped up the hole, before also not having enough time to discharge outside the hole, with the air pollution, the dirt bits that fall in pore. residual woman's persona mixes, through with the result of airborne sulfur dioxide " sulfuration ", black not only acid but also hard lump have been formed not only, get lodged in the hole of pore, and it is supportted greatly gradually.The blackhead pilosity is at forehead, bridge of the nose both sides and chin.
2. hoary hair's acne (white-head): peel off, peeling off the unpeeled dead angle of Buddhist monk cell plastid, clustering on pore and all around the oils and fats of gushing out can't be discharged smoothly, the result of pile-up has formed the small particles of size as the picture small rice grain at skin surface.Hoary hair's acne are easier to appear at cheek and lower jaw place.
3. comedo (Pimple): sometimes, crowded pore again holds pressure that can't stand that this is saturated, and oils and fats, antibacterial, dead cell, the dirt bits of clustering in pore are saved up strength to start out, and prepares broken capsule and goes out.At this moment, wait for the blood circulation prepare for war at any time, also transported a large amount of leukocytes and reinforced that therefore, the inflammatory response of hyperemia, swelling, pain has appearred in skin surface.
4. capsule spore (cysts): if the compositions of oils and fats, antibacterial, dead cell, dirt bits, clique in groups, go underground, when sabotaging, the team that this is strong, just between the connective tissue of skin corium, flee everywhere, attack the sebaceous gland of not blocking as yet, finally cause the infection of skin corium, form redness at skin surface, the large tracts of land inflammatory reaction of caking.
Generally speaking, the acne pilosity is born in hot summer, and this is owing to the rising along with the weather temperature, the secretion of sebaceous gland also can increase, thereby, arrived hot summer, also can not steep by greasy sweat stain even if many people do not put the oil, the chance that acne takes place has also just increased naturally.And enter autumn and winter season, and it is dry and cold that weather becomes, and the smegma function reduces, and skin also increases greasy demand, thereby also just not having too much sebum gets lodged in pore.Here it is acne increases the weight of the origin cause of formation that the autumn and winter alleviate summer.
Yet what of smegma only are one of reasons of forming of acne.Lack trace element " zinc " in the body constitution meta-acid, body, that taste have is damp and hot, large intestine has scorching or the like factor, all can bring out acne.
The traditional Chinese medical science thinks that acne belongs to categories such as " rosacea caused by lung-wind ", " pimples ", and it is strongly fragrant in local face mostly to be affection of exogenous wind-cold, wind heat, rheumatism, and strongly fragrant fire-transformation of a specified duration causes blockage of main and collateral channels, the expectorant blood coagulation stasis of blood, generation acne.Strongly fragrant suppuration of a specified duration just can generate skin sore, pathogen usually intruding into collateral in protracted disease, and lump formation due to accumulation of pathogens, or damage face skin then becomes tuberosity, cicatrix excessively for a long time.In addition, the plain body sun of patient heat is contained partially, and the pungent greasy food of surfeit makes damp and hot amassing in gastrointestinal in addition, and gastrointestinal is damp and hot can not be assigned, and superinverse is steamed in lung on the contrary, accumulates and hinders in face, the sick expectorant of giving birth to for a long time, and the tired stasis of blood is tied skin mutually and is formed.
The traditional Chinese medical science is divided into four types with acne:
1. lung meridian intrinsic heat type: mainly show as acne from the beginning of, congestion and swelling pain, facial pruritus can have xerostomia, and yellow urine is hard and dry, red tongue with yellow fur, the floating number of pulse condition.
2. spleen and stomach damp-heat type: it is frequent mainly to show as the acne outbreak, and can extrude the sample fat bolt of cracking rice of yellow-white, or pus is arranged, the fuel-displaced light of face, companion's halitosis bitter taste, bad during the appetite fashion, stool viscous is not well, red tongue with yellowish and greasy fur, pulse condition stringy and rapid pulse.
3. blood stasis phlegm stagnation type: mainly show as acne with the passing of time, the hard difficulty of quality disappears, and has pressed pain, and perhaps face is concavo-convex as orange peel, the women can have that menstrual blood volume is few, dysmenorrhea and menstrual period acne symptom, the dark thin fur of tongue, hesitant pulse such as increase the weight of.This kind of is more common in long-term chronic patients.
4. type of depression of QI: mainly show as erythra and be distributed in face and thoracic dorsal, with uncomfortable in chestly do not relax, both sides of the chest distending pain, happiness be sulky, female menstrual period front face skin lesion increases the weight of distending pain of the breast.
The traditional Chinese medical science adopts heat-clearing and toxic substances removing, preventing phlegm from forming and stopping coughing, blood circulation promoting and blood stasis dispelling, this disease of the decoction for the treatment of antiinflammatory softening the hard mass.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of acne.
The present invention also aims to provide a kind of preparation method of this Chinese medicine composition.
In order to realize purpose of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of acne, be to make by effective ingredient and/or pharmaceutically acceptable carrier, described effective ingredient is made by weight by following raw materials according:
Semen Coicis 10-20 part Flos Lonicerae 5-10 part Herba Houttuyniae 15-20 part
Herba Portulacae 5-15 part Folium Mori 10-15 part Radix Adenophorae (Radix Glehniae) 20-30 part
Bulbus Lilii 25-30 part Rhizoma Dioscoreae 15-25 part Semen Persicae 5-15 part
Gypsum Fibrosum 10-20 part Herba Leonuri 15-25 part Fructus Forsythiae 10-20 part
Radix Scutellariae 20-30 part Radix Salviae Miltiorrhizae 15-25 part Pericarpium Citri Reticulatae 20-30 part
Fructus Cnidii 10-20 part Rhizoma Atractylodis 10-30 part Herba Patriniae 5-10 part
Radix Tylophorae arenicolae 10-15 part Folium Ginseng 10-20 part
Effective ingredient is preferably made by weight by following raw materials according:
18 parts of 8 parts of Herba Houttuyniae of 16 portions of Flos Loniceraes of Semen Coicis
26 parts of 13 parts of Radix Adenophorae (Radix Glehniae) of 11 parts of Folium Mori of Herba Portulacae
11 parts in 21 parts of Semen Persicaes of 28 portions of Rhizoma Dioscoreaes of Bulbus Lilii
16 parts of 22 parts of Fructus Forsythiaes of 15 parts of Herba Leonuris of Gypsum Fibrosum
26 parts of 20 parts of Pericarpium Citri Reticulataes of 26 parts of Radix Salviae Miltiorrhizaes of Radix Scutellariae
8 parts of 22 parts of Herba Patriniae of 16 parts of Rhizoma Atractylodis of Fructus Cnidii
16 parts of 13 parts of Folium Ginseng of Radix Tylophorae arenicolae
Pharmaceutical composition of the present invention can with receivable carrier pharmaceutically, for example: filler such as starch, microcrystalline Cellulose etc.; Binding agent such as vitamin derivative, starch etc.; Mode by granule, capsule, tablet oral administration is used.
Chinese medicine composition of the present invention has heat-clearing and toxic substances removing, preventing phlegm from forming and stopping coughing, blood circulation promoting and blood stasis dispelling, and the effect of antiinflammatory softening the hard mass is used for that damp-heat in the spleen and stomach, blood stasis expectorant coagulate, lung-heat heat in blood institute is to diseases such as acnes.
The specific embodiment:
Following examples are used to illustrate the present invention, but are not used for limiting the scope of the invention.
Embodiment 1: Chinese medicinal composition granules of the present invention
(1) to be ground into impalpable powder standby for Gypsum Fibrosum 150g;
(2) Flos Lonicerae 80g, Rhizoma Dioscoreae 210g, Radix Salviae Miltiorrhizae 200g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Semen Coicis 160g, Herba Houttuyniae 180g, Herba Portulacae 110g, Folium Mori 130g, Radix Adenophorae (Radix Glehniae) 260g, Bulbus Lilii 280g, Semen Persicae 110g, Herba Leonuri 220g, Fructus Forsythiae 160g, Radix Scutellariae 260g, Pericarpium Citri Reticulatae 260g, Fructus Cnidii 160g, Rhizoma Atractylodis 220g, Herba Patriniae 80g, Radix Tylophorae arenicolae 130g, Folium Ginseng 160g decocts with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder and clear paste, drying is ground into fine powder, adds dextrin 600g, lactose 200g, mixing, with 80% ethanol wet granulation promptly.
Embodiment 2: Chinese medicinal composition capsules agent of the present invention
(1) to be ground into impalpable powder standby for Gypsum Fibrosum 150g;
(2) Flos Lonicerae 80g, Rhizoma Dioscoreae 210g, Radix Salviae Miltiorrhizae 200g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Semen Coicis 160g, Herba Houttuyniae 180g, Herba Portulacae 110g, Folium Mori 130g, Radix Adenophorae (Radix Glehniae) 260g, Bulbus Lilii 280g, Semen Persicae 110g, Herba Leonuri 220g, Fructus Forsythiae 160g, Radix Scutellariae 260g, Pericarpium Citri Reticulatae 260g, Fructus Cnidii 160g, Rhizoma Atractylodis 220g, Herba Patriniae 80g, Radix Tylophorae arenicolae 130g, Folium Ginseng 160g decocts with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder and clear paste, drying is ground into fine powder, add dextrin 500g, sieve, mixing, in the capsulae vacuus of packing into promptly.
Embodiment 3 Chinese medicine composition tablets of the present invention
(1) to be ground into impalpable powder standby for Gypsum Fibrosum 150g;
(2) Flos Lonicerae 80g, Rhizoma Dioscoreae 210g, Radix Salviae Miltiorrhizae 200g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Semen Coicis 160g, Herba Houttuyniae 180g, Herba Portulacae 110g, Folium Mori 130g, Radix Adenophorae (Radix Glehniae) 260g, Bulbus Lilii 280g, Semen Persicae 110g, Herba Leonuri 220g, Fructus Forsythiae 160g, Radix Scutellariae 260g, Pericarpium Citri Reticulatae 260g, Fructus Cnidii 160g, Rhizoma Atractylodis 220g, Herba Patriniae 80g, Radix Tylophorae arenicolae 130g, Folium Ginseng 160g adds 8 times of decoctings and boils secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder and clear paste, drying, be ground into fine powder, add starch 300g, microcrystalline Cellulose 100g and carboxymethylstach sodium 3g are with 80% ethanol wet granulation, tabletting, coating are promptly.
Claims (4)
1, a kind of Chinese medicine composition for the treatment of acne is to be made by effective ingredient and/or pharmaceutically acceptable carrier, it is characterized in that described effective ingredient is made by weight by following raw materials according:
Semen Coicis 10-20 part Flos Lonicerae 5-10 part Herba Houttuyniae 15-20 part
Herba Portulacae 5-15 part Folium Mori 10-15 part Radix Adenophorae (Radix Glehniae) 20-30 part
Bulbus Lilii 25-30 part Rhizoma Dioscoreae 15-25 part Semen Persicae 5-15 part
Gypsum Fibrosum 10-20 part Herba Leonuri 15-25 part Fructus Forsythiae 10-20 part
Radix Scutellariae 20-30 part Radix Salviae Miltiorrhizae 15-25 part Pericarpium Citri Reticulatae 20-30 part
Fructus Cnidii 10-20 part Rhizoma Atractylodis 10-30 part Herba Patriniae 5-10 part
Radix Tylophorae arenicolae 10-15 part Folium Ginseng 10-20 part.
2, Chinese medicine composition as claimed in claim 2 is characterized in that described effective ingredient made by weight by following raw materials according:
18 parts of 8 parts of Herba Houttuyniae of 16 portions of Flos Loniceraes of Semen Coicis
26 parts of 13 parts of Radix Adenophorae (Radix Glehniae) of 11 parts of Folium Mori of Herba Portulacae
11 parts in 21 parts of Semen Persicaes of 28 portions of Rhizoma Dioscoreaes of Bulbus Lilii
16 parts of 22 parts of Fructus Forsythiaes of 15 parts of Herba Leonuris of Gypsum Fibrosum
26 parts of 20 parts of Pericarpium Citri Reticulataes of 26 parts of Radix Salviae Miltiorrhizaes of Radix Scutellariae
8 parts of 22 parts of Herba Patriniae of 16 parts of Rhizoma Atractylodis of Fructus Cnidii
16 parts of 13 parts of Folium Ginseng of Radix Tylophorae arenicolae.
3,, it is characterized in that described Chinese medicine composition can be made into granule, capsule and tablet as the arbitrary described Chinese medicine composition of claim 1-2.
4, a kind of preparation method as the arbitrary described Chinese medicine composition of claim 1-3 comprises the steps:
(1) to be broken into impalpable powder standby for gypsum powder;
(2) Flos Lonicerae, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Semen Coicis, Herba Houttuyniae, Herba Portulacae, Folium Mori, Radix Adenophorae (Radix Glehniae), Bulbus Lilii, Semen Persicae, Herba Leonuri, Fructus Forsythiae, Radix Scutellariae, Pericarpium Citri Reticulatae, Fructus Cnidii, Rhizoma Atractylodis, Herba Patriniae, Radix Tylophorae arenicolae, Folium Ginseng decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder and clear paste, drying, be ground into fine powder, make granule, capsule and tablet with pharmaceutically acceptable carrier.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2008101034226A CN101549120A (en) | 2008-04-03 | 2008-04-03 | Traditional Chinese medicine composition for treating acne vulgaris and preparation method thereof |
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| CNA2008101034226A CN101549120A (en) | 2008-04-03 | 2008-04-03 | Traditional Chinese medicine composition for treating acne vulgaris and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101919980A (en) * | 2010-08-18 | 2010-12-22 | 张益士 | Traditional Chinese medicine composition for treating acne whelks |
| CN102687878A (en) * | 2012-05-21 | 2012-09-26 | 何圣 | Beauty-care soup for relieving summer heat and cooling and method for manufacturing the same |
| CN102813854A (en) * | 2012-09-10 | 2012-12-12 | 辛如才 | Chinese herbal medicine paste used for treating acne |
| CN105412707A (en) * | 2016-01-18 | 2016-03-23 | 吴苏文 | Traditional Chinese medicine powder for treating damp heat stagnation type acnes and preparation method of traditional Chinese medicine powder |
-
2008
- 2008-04-03 CN CNA2008101034226A patent/CN101549120A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101919980A (en) * | 2010-08-18 | 2010-12-22 | 张益士 | Traditional Chinese medicine composition for treating acne whelks |
| CN102687878A (en) * | 2012-05-21 | 2012-09-26 | 何圣 | Beauty-care soup for relieving summer heat and cooling and method for manufacturing the same |
| CN102813854A (en) * | 2012-09-10 | 2012-12-12 | 辛如才 | Chinese herbal medicine paste used for treating acne |
| CN102813854B (en) * | 2012-09-10 | 2014-07-16 | 山东大学齐鲁医院 | Chinese herbal medicine paste used for treating acne |
| CN105412707A (en) * | 2016-01-18 | 2016-03-23 | 吴苏文 | Traditional Chinese medicine powder for treating damp heat stagnation type acnes and preparation method of traditional Chinese medicine powder |
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Open date: 20091007 |