CN101542287B - 磁性识别系统 - Google Patents

磁性识别系统 Download PDF

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Publication number
CN101542287B
CN101542287B CN200780041074.8A CN200780041074A CN101542287B CN 101542287 B CN101542287 B CN 101542287B CN 200780041074 A CN200780041074 A CN 200780041074A CN 101542287 B CN101542287 B CN 101542287B
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China
Prior art keywords
magnetic
label
analyte
binding
moiety
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Expired - Fee Related
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CN200780041074.8A
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English (en)
Chinese (zh)
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CN101542287A (zh
Inventor
普拉把尤特·德哈尔
大卫·普里查德
克莱尔·吉克
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ITI Scotland Ltd
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ITI Scotland Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN200780041074.8A 2006-11-02 2007-11-02 磁性识别系统 Expired - Fee Related CN101542287B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0621894.5 2006-11-02
GBGB0621894.5A GB0621894D0 (en) 2006-11-02 2006-11-02 Magnetic recognition system
PCT/GB2007/004188 WO2008053229A1 (en) 2006-11-02 2007-11-02 Magnetic recognition system

Publications (2)

Publication Number Publication Date
CN101542287A CN101542287A (zh) 2009-09-23
CN101542287B true CN101542287B (zh) 2014-04-16

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ID=37547250

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200780041074.8A Expired - Fee Related CN101542287B (zh) 2006-11-02 2007-11-02 磁性识别系统

Country Status (9)

Country Link
US (1) US20100159442A1 (enExample)
EP (2) EP2089714B1 (enExample)
JP (1) JP5453095B2 (enExample)
CN (1) CN101542287B (enExample)
AU (1) AU2007315904A1 (enExample)
CA (1) CA2668011A1 (enExample)
GB (1) GB0621894D0 (enExample)
RU (1) RU2442169C2 (enExample)
WO (1) WO2008053229A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0808086D0 (en) * 2008-05-02 2008-06-11 Iti Scotland Ltd Magnetic proteins for in vivo imaging
GB0808089D0 (en) * 2008-05-02 2008-06-11 Iti Scotland Ltd magnetic recognition system
JP5408905B2 (ja) * 2008-05-27 2014-02-05 義弘 石川 抗体又は抗原の定量方法
CN103308373A (zh) * 2013-06-05 2013-09-18 南昌大学 磁珠分离大肠杆菌o157的方法
PT3186192T (pt) * 2014-09-30 2018-04-09 Thena Biotech S R L Uma proteína de fusão, uma nanopartícula composta por uma pluralidade de monómeros da dita proteína de fusão e utilizações das mesmas
CN105842456A (zh) * 2015-01-14 2016-08-10 北京康诺生物科技有限公司 一种乳铁蛋白定向免疫磁珠及其制备方法和用途
KR20160094550A (ko) * 2015-01-30 2016-08-10 동국대학교 산학협력단 단일사슬항체조각과 페리틴을 포함하는 융합단백질 및 그의 용도
US20250075003A1 (en) * 2021-05-07 2025-03-06 Uif (University Industry Foundation), Yonsei University Nanoparticles comprising fusion protein of single-chain variable fragment and ferritin, and use thereof
CN118556885B (zh) * 2024-05-22 2025-10-03 江苏大学 一种低通量电磁吸附乳铁蛋白的高压静电喷雾干燥装置及其应用

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DE2656317C2 (de) * 1976-12-11 1986-06-19 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verfahren zur Herstellung einer Suspension von beladenen Erythrocyten
US4732864A (en) * 1983-10-06 1988-03-22 E. I. Du Pont De Nemours And Company Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules
WO1990006323A2 (en) * 1988-11-29 1990-06-14 Centocor, Inc. Chimeric proteins incorporating a metal binding protein
US5612019A (en) * 1988-12-19 1997-03-18 Gordon, Deceased; David Diagnosis and treatment of HIV viral infection using magnetic metal transferrin particles
US5248589A (en) * 1991-02-21 1993-09-28 Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Separation of cells and biological macromolecules by ferritin conjugates
JPH05209884A (ja) * 1991-10-11 1993-08-20 Tdk Corp 抗原、抗体検出方法
US5491219A (en) * 1993-06-11 1996-02-13 Protein Magnetics Ferritin with ferrimagnetically ordered ferrite core and method technical field
WO1995004753A1 (en) * 1993-08-11 1995-02-16 University Of New Mexico Compositions of fusion proteins containing metallothionein and targeting-protein structural components
US5514340A (en) * 1994-01-24 1996-05-07 Magnetix Biotechnology, Inc. Device for separating magnetically labelled cells
WO1997035964A1 (en) 1996-03-27 1997-10-02 Tdk Corporation Fine magnetic particles containing useful proteins bound thereto, process for producing the same, and use thereof
US6337215B1 (en) * 1997-12-01 2002-01-08 International Business Machines Corporation Magnetic particles having two antiparallel ferromagnetic layers and attached affinity recognition molecules
US6251130B1 (en) * 1998-03-24 2001-06-26 Innercool Therapies, Inc. Device for applications of selective organ cooling
US7232691B2 (en) * 2001-11-27 2007-06-19 Los Alamos National Security, Llc Bioassay and biomolecular identification, sorting, and collection methods using magnetic microspheres
US7998704B2 (en) * 2002-03-07 2011-08-16 Carnegie Mellon University Methods for magnetic resonance imaging
CN1659187A (zh) * 2002-05-10 2005-08-24 新世纪药品有限公司 融合铁蛋白在疫苗和其他方面的应用
WO2004083902A2 (en) 2002-10-25 2004-09-30 Georgia Tech Research Corporation Multifunctional magnetic nanoparticle probes for intracellular molecular imaging and monitoring
WO2004088313A1 (en) * 2003-04-02 2004-10-14 Tero Soukka Nanoparticle for bioaffinity assays
US6972095B1 (en) 2003-05-07 2005-12-06 Electric Power Research Institute Magnetic molecules: a process utilizing functionalized magnetic ferritins for the selective removal of contaminants from solution by magnetic filtration
US7846201B2 (en) * 2004-02-20 2010-12-07 The Children's Hospital Of Philadelphia Magnetically-driven biodegradable gene delivery nanoparticles formulated with surface-attached polycationic complex
JP2006010529A (ja) * 2004-06-25 2006-01-12 Canon Inc 磁性粒子分離装置および分離方法
WO2006017428A2 (en) 2004-08-03 2006-02-16 Becton, Dickinson And Company Use of magnetic material to direct isolation of compounds and fractionation of multipart samples
US20080093219A1 (en) * 2005-03-15 2008-04-24 Tufts University Magnetic Protein Nanosensors and Methods of Use
WO2006104700A1 (en) 2005-03-15 2006-10-05 Tufts University Magnetic protein nanosensors and methods of use
US20060240456A1 (en) 2005-03-22 2006-10-26 Liaohai Chen Nanosized biological container and manufacture thereof
US7164010B1 (en) * 2005-09-28 2007-01-16 Academia Sinica Molecular magnetic protein
WO2008048288A2 (en) * 2005-11-09 2008-04-24 Montana State University Novel nanoparticles and use thereof
WO2007058454A1 (en) * 2005-11-15 2007-05-24 Cgk Co., Ltd. System for detecting molecular interactions

Also Published As

Publication number Publication date
CN101542287A (zh) 2009-09-23
CA2668011A1 (en) 2008-05-08
EP2428799A1 (en) 2012-03-14
AU2007315904A1 (en) 2008-05-08
EP2089714A1 (en) 2009-08-19
JP2010508530A (ja) 2010-03-18
GB0621894D0 (en) 2006-12-13
JP5453095B2 (ja) 2014-03-26
EP2089714B1 (en) 2012-10-10
US20100159442A1 (en) 2010-06-24
RU2442169C2 (ru) 2012-02-10
RU2009120688A (ru) 2010-12-10
WO2008053229A1 (en) 2008-05-08

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Granted publication date: 20140416

Termination date: 20161102