CN101537143A - Chinese traditional medicine composition for curing chronic gastritis and preparation method thereof - Google Patents
Chinese traditional medicine composition for curing chronic gastritis and preparation method thereof Download PDFInfo
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- CN101537143A CN101537143A CN200810102425A CN200810102425A CN101537143A CN 101537143 A CN101537143 A CN 101537143A CN 200810102425 A CN200810102425 A CN 200810102425A CN 200810102425 A CN200810102425 A CN 200810102425A CN 101537143 A CN101537143 A CN 101537143A
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Abstract
The invention relates to a Chinese traditional medicine composition for curing chronic gastritis. The Chinese traditional medicine composition is prepared by white atractylodes rhizome, immature bitter orange, cuttlebone, rhubarb, Indian bread, hawthorn fruit, malt, lentil, auckandia root, pinellia tuber, medicated leaven, tangerine peel, Chinese yam, chickens gizzard-membrane, magnolia bark, calcined concha arcae and/or a pharmaceutically accepted carrier. The invention also relates to a preparation method of the Chinese traditional medicine composition. The Chinese traditional medicine composition has the effects of strengthening spleen and regulating the middle warmer, improving digestion and appetizing, tonifying middle-Jiao and Qi and nourishing Yin to raise the stomach and is used for various symptoms such as upper abdominal pain, abdominal distention, belching, anorexia, and the like caused by the chronic gastritis.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, specifically, relate to a kind of Chinese medicine composition for the treatment of chronic gastritis and preparation method thereof.
Background technology
Chronic gastritis means the various chronic gastric mucosa inflammatory lesion that the different causes of disease cause, is a kind of commonly encountered diseases, also is one of army's frequently-occurring disease, and its sickness rate ranks first in various gastropathy.
Chronic gastritis can be divided three classes: 1. superficial gastritis.2. atrophic gastritis.3. hypertrophic gastritis.
The cause of disease and the pathogeny of chronic gastritis are not illustrated as yet fully, may be relevant with following factors:
One, the sequel of acute gastritis: after the acute gastritis, gastric mucosal lesion more or does not repeatedly show effect lastingly, all can form chronic gastritis.
Two, irritable food and medicine: take the diet and the medicine that gastric mucosa there are intense stimulus for a long time, as strong tea, spirits, pungent or salicylic acid salt medicine, or excessively smoking.
Three, the anti-stream of duodenal juice.
Four, immune factor.
Five, infective agent: also can find anti-pylori antibody in patient's blood He in the gastric mucosa.Behind antibiotic therapy,, symptom and histology can improve disappearance even changing.
In addition, the common factor relevant with the chronic gastritis morbidity has: the acute gastritis protracted course of disease, long-term feed is too fast, without carefully just chewing food is swallowed, food do not have regularly, the time famine when full, long-term drink or edible ardent spirits, Fructus Capsici, irritable foods such as mustard, excessive smoking, the long-term drink strong tea is often taken the medicine of infringement such as aspirin stomach.Patient Chang Ke feels that epigastrium pain is glutted, and feed back pain increases the weight of, and loss of appetite is arranged, feels sick, heating installation, vomits or burn feeling, acid regurgitation water are arranged, and all diseases are increased the weight of during the feed greasy food.With course of disease delay, patient also has lassitude, work efficiency to reduce, and health is weak, slight tenderness is often arranged under epigastrium and the xiphoid-process.This patient's diet maintenance is very important, and food is suitable soft, digestion and being rich in nutrition easily, have many meals but little food at eath, and gluttony crapulence not, full when hungry in the time of not, diet tobacco and wine and pungent irritable food, notes will be avoided catching cold catching a cold, and keep the emotion happiness.
Primary disease is made slow progress, the Chang Fanfu outbreak, and good morbidity above middle age, and the tendency that sickness rate increases with age growth is arranged.Part patient can not have any symptom, and most of patients can have indigestion symptom in various degree, and sign is not obvious.Its performance of various gastritis is not quite similar:
One, superficial gastritis: chronic irregular upper abdomen dull pain, abdominal distention, belch etc. can be arranged, and obvious during especially with improper diet, part patient can have acid regurgitation, upper gastrointestinal hemorrhage, and this type of patient's gastroscope confirmation erosive and gastritis verrucosa are in the majority.
Two, atrophic gastritis: dissimilar, its symptom of different parts is phase not also.The general symptom of digestive tract of body of stomach gastritis is less, can occur obvious anorexia sometimes, lose weight, glossitis, atrophy of tongue papillae.Gastrointestinal symptom was more obvious when atrophic gastritis influenced gastric antrum, when especially bile reflux being arranged, often showed as midriff pain on the persistence, after feed, promptly go out, can upper gastrointestinal hemorrhage in a small amount can be arranged repeatedly sometimes, even hematemesis occurs with containing biliary vomitus and retrosternal pain and burn feeling.
Chronic gastritis is no obvious sign mostly, and the light tenderness of epigastrium can be arranged sometimes.
The traditional Chinese medical science thinks that chronic gastritis belongs to sick categories such as " gastric abscess ", " feeling of fullness ", " acid regurgitation ", " noisy ", " indigestion and loss of appetite ".These are sick many because of feelings will is unsuccessful for a long time, eating and drinking without temperance, and work and rest is not normal, causes depression of liver-QI, dysfunction of the spleen in transportation, gastral cavilty is become estranged, and with the passing of time middle gas loses empty, thereby causes all symptoms.
The traditional Chinese medical science is divided into seven types with this disease:
1, spleen-stomach deficiency-cold: gastral cavilty weighs down to expand and does not relax, inappetence, and acid regurgitation has a dull ache, and meets cold increasing the weight of, must warm up then light, when starving painful very, feed subtracts loose stool slightly, spiritlessness and weakness, there is the tooth seal on pale tongue, fat big, limit, white and thin fur, pulse condition is heavy thin and delicate or floating unable greatly.Card belongs to deficiency of QI in middle-JIAO, Deficiency and coldness of spleen and stomach, suitable invigorating the spleen and replenishing QI, spleen invigorating stomach warming.
2, stomach-Yin deficiency: the scorching hot pain of gastral cavilty, noisy discomfort, though famine and poor appetite, xerostomia is thirsty, and it is involved and abstruse to defecate, and red tongue has crackle, the stripping of tongue fur light or few tongue, pulse condition stringy and thready pulse number.Card belongs to incoordination between the liver and spleen, stomach-Yin is lost void, suitable soothing liver and strengthening spleen, tonifying YIN nourishing the stomach.
3, pathogenic heat is violated gastric pattern: the scorching hot pain of gastral cavilty, noisy easy famine, bitter taste in the mouth and dry throat, general acid regurgitation misery, constipation, red tongue yellow and thin fur, pulse condition stringy and thready pulse.Card belongs to pathogenic heat and violates stomach, middle burnt stasis, should dredge burnt, clearing heat to ease the stomach in the profit.
4, stagnation of liver-QI is violated gastric pattern: gastral cavilty feeling of fullness dull pain, two side of body supports pain that expands, belch is frequent, the time pantothenic acid is arranged, loss of appetite, the little Huang of red tongue white and thin fur, pulse condition stringy and thready pulse.Card belongs to stagnation of QI due to depression of the liver, stomach-QI being unable to descend normally, suitable depressed liver-energy dispersing and QI regulating, spleen invigorating peace stomach.
5, the dyspepsia type that injures one's stomach: gastral cavilty twinge or sharp pain, the sore spot tenderness, the time sense stomach scorching hot noisy, poor appetite, body of the tongue is dark violet the ecchymosis yellow and thin fur, pulse condition is not smooth.Card belongs to qi depression to blood stasis, hot and suffocating injuring one's stomach.Suitable blood circulation promoting and blood stasis dispelling, circulation of qi promoting reason stomach.
6, liver-fire invading the stomach type: because of the prolonged illness deficiency of spleen-QI and stomach-QI, feelings will is not relaxed, and is strongly fragrant and fire-transformation causes gastral cavilty feeling of fullness dull pain, and food back pain increases the weight of, frequent heartburn pantothenic acid, and the bitter taste stickness, the loose stool, body of the tongue is light red, yellow and greasy fur, thready and rapid pulse.Card belongs to simulataneous insufficiency and excessive, liver-fire invading the stomach.Control suitable liver-smoothing, qi-regulating, heat clearing away accent stomach.
7, the spleen and stomach being stranded by dampness type: fullness and oppression in the stomach, indigestion and loss of appetite, lack the i.e. sense of food and expand, tastelessness lacks drink yearningly, the borborygmus rumbling, loose stool, heavy sensation of the body is weak, and sleepy lazyness is moving, and the fat tongue of pale tongue is greasy in vain, and pulse condition moistens carefully.Card belongs to wet resistance taste, is stranded and holds back middle Jiao.Should invigorating the spleen to clear away damp pathogen, the awake stomach of regulating the flow of vital energy.
The traditional Chinese medical science adopt spleen invigorating and in, this disease of decoction for the treatment of digesting and appetizing, invigorating the spleen and replenishing QI, tonifying YIN nourishing the stomach.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of chronic gastritis.
The present invention also aims to provide a kind of preparation method of this Chinese medicine composition.
In order to realize purpose of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of chronic gastritis, be to make by effective ingredient and/or pharmaceutically acceptable carrier, described effective ingredient is made by weight by following raw materials according:
Rhizoma Atractylodis Macrocephalae 10-20 part Fructus Aurantii Immaturus 5-15 part Endoconcha Sepiae 15-20 part
Radix Et Rhizoma Rhei 5-10 part Poria 15-25 part Fructus Crataegi 20-25 part
Fructus Hordei Germinatus 15-20 part Seem Lablab Album 10-15 part Radix Aucklandiae 10-20 part
Rhizoma Pinelliae 5-15 part Massa Medicata Fermentata 20-30 part Pericarpium Citri Reticulatae 15-25 part
Rhizoma Dioscoreae 5-15 part Endothelium Corneum Gigeriae Galli 15-25 part Cortex Magnoliae Officinalis 10-20 part
Concha Arcae (calcined) 15-20 part
Effective ingredient is preferably made by weight by following raw materials according:
18 parts of 11 portions of Endoconcha Sepiaes of 16 parts of Fructus Aurantii Immaturuss of the Rhizoma Atractylodis Macrocephalae
23 parts of 21 portions of Fructus Crataegis of 8 parts of Poria of Radix Et Rhizoma Rhei
16 parts of 13 parts of Radix Aucklandiae of 18 portions of Seem Lablab Albums of Fructus Hordei Germinatus
21 parts of 26 parts of Pericarpium Citri Reticulataes of 11 parts of Massa Medicata Fermentata of the Rhizoma Pinelliae
16 parts of 22 parts of Cortex Magnoliae Officinalis of 11 parts of Endothelium Corneum Gigeriae Galli of Rhizoma Dioscoreae
18 parts of Concha Arcae (calcined)
The present invention also provides a kind of preparation method of this Chinese medicine composition, comprises the steps:
(1) to be broken into impalpable powder standby for Radix Et Rhizoma Rhei powder;
(2) Fructus Crataegi, Seem Lablab Album, the Rhizoma Pinelliae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, Endoconcha Sepiae, Poria, Fructus Hordei Germinatus, the Radix Aucklandiae, Massa Medicata Fermentata, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, Endothelium Corneum Gigeriae Galli, Cortex Magnoliae Officinalis, Concha Arcae (calcined) decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder and clear paste, drying, be ground into fine powder, make granule, capsule and pill with pharmaceutically acceptable carrier.
Pharmaceutical composition of the present invention can with receivable carrier pharmaceutically, for example: filler such as starch, microcrystalline Cellulose etc.; Binding agent such as vitamin derivative, starch etc.; Mode by granule, capsule, tablet oral administration is used.
Chinese medicine composition of the present invention have spleen invigorating and in, the effect of digesting and appetizing, invigorating the spleen and replenishing QI, tonifying YIN nourishing the stomach, be used for diseases such as upper abdomen dull pain that chronic gastritis causes, abdominal distention, belch, anorexia.
The specific embodiment
Following examples are used to illustrate the present invention, but are not used for limiting the scope of the invention.
Embodiment 1: Chinese medicinal composition granules of the present invention
(1) to be ground into impalpable powder standby for Radix Et Rhizoma Rhei 80g;
(2) Fructus Crataegi 230g, Seem Lablab Album 130g, Rhizoma Pinelliae 110g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Rhizoma Atractylodis Macrocephalae 160g, Fructus Aurantii Immaturus 110g, Endoconcha Sepiae 180g, Poria 210g, Fructus Hordei Germinatus 180g, Radix Aucklandiae 160g, Massa Medicata Fermentata 260g, Pericarpium Citri Reticulatae 210g, Rhizoma Dioscoreae 110g, Endothelium Corneum Gigeriae Galli 220g, Cortex Magnoliae Officinalis 160g, Concha Arcae (calcined) 180g decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder and clear paste, drying is ground into fine powder, adds dextrin 1000g, lactose 800g, mixing, with 75% ethanol wet granulation promptly.
Embodiment 2: Chinese medicinal composition capsules agent of the present invention
(1) to be ground into impalpable powder standby for Radix Et Rhizoma Rhei 80g;
(2) Fructus Crataegi 230g, Seem Lablab Album 130g, Rhizoma Pinelliae 110g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Rhizoma Atractylodis Macrocephalae 160g, Fructus Aurantii Immaturus 110g, Endoconcha Sepiae 180g, Poria 210g, Fructus Hordei Germinatus 180g, Radix Aucklandiae 160g, Massa Medicata Fermentata 260g, Pericarpium Citri Reticulatae 210g, Rhizoma Dioscoreae 110g, Endothelium Corneum Gigeriae Galli 220g, Cortex Magnoliae Officinalis 160g, Concha Arcae (calcined) 180g decoct with water secondary, each 2 hours, filter merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder and clear paste, dry, be ground into fine powder, add dextrin 700g mixing, in the capsulae vacuus of packing into promptly.
Embodiment 3: Chinese medicine composition pill of the present invention
(1) to be ground into impalpable powder standby for Radix Et Rhizoma Rhei 80g;
(2) Fructus Crataegi 230g, Seem Lablab Album 130g, Rhizoma Pinelliae 110g are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Rhizoma Atractylodis Macrocephalae 160g, Fructus Aurantii Immaturus 110g, Endoconcha Sepiae 180g, Poria 210g, Fructus Hordei Germinatus 180g, Radix Aucklandiae 160g, Massa Medicata Fermentata 260g, Pericarpium Citri Reticulatae 210g, Rhizoma Dioscoreae 110g, Endothelium Corneum Gigeriae Galli 220g, Cortex Magnoliae Officinalis 160g, Concha Arcae (calcined) 180g decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder and clear paste, drying is ground into fine powder, add refined honey 50g and an amount of water, general ball, drying, promptly.
Claims (4)
1, a kind of Chinese medicine composition for the treatment of chronic gastritis is to be made by effective ingredient and/or pharmaceutically acceptable carrier, it is characterized in that described effective ingredient is made by weight by following raw materials according:
Rhizoma Atractylodis Macrocephalae 10-20 part Fructus Aurantii Immaturus 5-15 part Endoconcha Sepiae 15-20 part
Radix Et Rhizoma Rhei 5-10 part Poria 15-25 part Fructus Crataegi 20-25 part
Fructus Hordei Germinatus 15-20 part Seem Lablab Album 10-15 part Radix Aucklandiae 10-20 part
Rhizoma Pinelliae 5-15 part Massa Medicata Fermentata 20-30 part Pericarpium Citri Reticulatae 15-25 part
Rhizoma Dioscoreae 5-15 part Endothelium Corneum Gigeriae Galli 15-25 part Cortex Magnoliae Officinalis 10-20 part
Concha Arcae (calcined) 15-20 part.
2, Chinese medicine composition as claimed in claim 1 is characterized in that described effective ingredient made by weight by following raw materials according:
18 parts of 11 portions of Endoconcha Sepiaes of 16 parts of Fructus Aurantii Immaturuss of the Rhizoma Atractylodis Macrocephalae
23 parts of 21 portions of Fructus Crataegis of 8 parts of Poria of Radix Et Rhizoma Rhei
16 parts of 13 parts of Radix Aucklandiae of 18 portions of Seem Lablab Albums of Fructus Hordei Germinatus
21 parts of 26 parts of Pericarpium Citri Reticulataes of 11 parts of Massa Medicata Fermentata of the Rhizoma Pinelliae
16 parts of 22 parts of Cortex Magnoliae Officinalis of 11 parts of Endothelium Corneum Gigeriae Galli of Rhizoma Dioscoreae
18 parts of Concha Arcae (calcined).
3,, it is characterized in that described Chinese medicine composition can be made into granule, capsule and pill as the arbitrary described Chinese medicine composition of claim 1-2.
4, a kind of preparation method as the arbitrary described Chinese medicine composition of claim 1-3 comprises the steps:
(1) to be broken into impalpable powder standby for Radix Et Rhizoma Rhei powder;
(2) Fructus Crataegi, Seem Lablab Album, the Rhizoma Pinelliae are with 60% alcohol reflux secondary, and each one hour, gradation filtered, and it is the clear paste of 1.15 (60 ℃) that merging filtrate, concentrating under reduced pressure become relative density;
(3) Rhizoma Atractylodis Macrocephalae, Fructus Aurantii Immaturus, Endoconcha Sepiae, Poria, Fructus Hordei Germinatus, the Radix Aucklandiae, Massa Medicata Fermentata, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, Endothelium Corneum Gigeriae Galli, Cortex Magnoliae Officinalis, Concha Arcae (calcined) decoct with water secondary, each 2 hours, filter, merging filtrate left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder and clear paste, drying, be ground into fine powder, make granule, capsule and pill with pharmaceutically acceptable carrier.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810102425A CN101537143A (en) | 2008-03-21 | 2008-03-21 | Chinese traditional medicine composition for curing chronic gastritis and preparation method thereof |
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| CN200810102425A CN101537143A (en) | 2008-03-21 | 2008-03-21 | Chinese traditional medicine composition for curing chronic gastritis and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101745089B (en) * | 2009-12-16 | 2013-01-09 | 陈正华 | Medicament for treating stomach cancer and preparation method thereof |
| CN103041280A (en) * | 2013-01-22 | 2013-04-17 | 陈振卯 | Compound traditional Chinese medicine for diminishing inflammation, checking diarrhea and relieving pain |
| CN104352899A (en) * | 2014-10-30 | 2015-02-18 | 范鹏琳 | Traditional Chinese medicinal preparation for treating chronic gastritis |
| CN104547560A (en) * | 2014-12-08 | 2015-04-29 | 张仁勇 | Medicine for treating gastric diseases and preparation method thereof |
| CN105687425A (en) * | 2016-03-17 | 2016-06-22 | 袁尊山 | Capsule preparation for treating epigastralgia |
-
2008
- 2008-03-21 CN CN200810102425A patent/CN101537143A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101745089B (en) * | 2009-12-16 | 2013-01-09 | 陈正华 | Medicament for treating stomach cancer and preparation method thereof |
| CN103041280A (en) * | 2013-01-22 | 2013-04-17 | 陈振卯 | Compound traditional Chinese medicine for diminishing inflammation, checking diarrhea and relieving pain |
| CN103041280B (en) * | 2013-01-22 | 2014-08-27 | 陈振卯 | Compound traditional Chinese medicine for diminishing inflammation, checking diarrhea and relieving pain |
| CN104352899A (en) * | 2014-10-30 | 2015-02-18 | 范鹏琳 | Traditional Chinese medicinal preparation for treating chronic gastritis |
| CN104547560A (en) * | 2014-12-08 | 2015-04-29 | 张仁勇 | Medicine for treating gastric diseases and preparation method thereof |
| CN105687425A (en) * | 2016-03-17 | 2016-06-22 | 袁尊山 | Capsule preparation for treating epigastralgia |
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Open date: 20090923 |