CN101522711B - 具有改进性质的重组表面活性剂 - Google Patents

具有改进性质的重组表面活性剂 Download PDF

Info

Publication number
CN101522711B
CN101522711B CN2007800382767A CN200780038276A CN101522711B CN 101522711 B CN101522711 B CN 101522711B CN 2007800382767 A CN2007800382767 A CN 2007800382767A CN 200780038276 A CN200780038276 A CN 200780038276A CN 101522711 B CN101522711 B CN 101522711B
Authority
CN
China
Prior art keywords
polypeptide
surfactants
recombinant
faced
reconstituted surfactants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN2007800382767A
Other languages
English (en)
Chinese (zh)
Other versions
CN101522711A (zh
Inventor
J·约翰松
T·库斯泰德特
B·罗伯特松
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39079026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101522711(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Publication of CN101522711A publication Critical patent/CN101522711A/zh
Application granted granted Critical
Publication of CN101522711B publication Critical patent/CN101522711B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/395—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
CN2007800382767A 2006-10-13 2007-09-28 具有改进性质的重组表面活性剂 Active CN101522711B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06021521.7 2006-10-13
EP06021521 2006-10-13
PCT/IB2007/002841 WO2008044109A1 (en) 2006-10-13 2007-09-28 Reconstituted surfactants having improved properties

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201310053516.8A Division CN103169947B (zh) 2006-10-13 2007-09-28 具有改进性质的重组表面活性剂

Publications (2)

Publication Number Publication Date
CN101522711A CN101522711A (zh) 2009-09-02
CN101522711B true CN101522711B (zh) 2013-11-13

Family

ID=39079026

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2007800382767A Active CN101522711B (zh) 2006-10-13 2007-09-28 具有改进性质的重组表面活性剂
CN201310053516.8A Active CN103169947B (zh) 2006-10-13 2007-09-28 具有改进性质的重组表面活性剂

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201310053516.8A Active CN103169947B (zh) 2006-10-13 2007-09-28 具有改进性质的重组表面活性剂

Country Status (35)

Country Link
US (2) US8183210B2 (https=)
EP (1) EP2078038B1 (https=)
JP (2) JP5405307B2 (https=)
KR (1) KR101328851B1 (https=)
CN (2) CN101522711B (https=)
AR (2) AR063263A1 (https=)
AU (1) AU2007306075B2 (https=)
BR (1) BRPI0715317B1 (https=)
CA (1) CA2666344C (https=)
CL (1) CL2007002931A1 (https=)
CO (1) CO6400235A2 (https=)
CY (1) CY1114716T1 (https=)
DK (1) DK2078038T3 (https=)
EA (1) EA015802B1 (https=)
ES (1) ES2438727T3 (https=)
GE (1) GEP20125531B (https=)
HR (1) HRP20140052T1 (https=)
IL (1) IL198075A (https=)
JO (1) JO2963B1 (https=)
MA (1) MA31062B1 (https=)
ME (2) MEP12109A (https=)
MX (1) MX343064B (https=)
MY (1) MY148127A (https=)
NO (1) NO342038B1 (https=)
NZ (1) NZ576189A (https=)
PE (1) PE20081184A1 (https=)
PL (1) PL2078038T3 (https=)
PT (1) PT2078038E (https=)
RS (1) RS53172B (https=)
SI (1) SI2078038T1 (https=)
TN (1) TN2009000099A1 (https=)
TW (1) TWI388333B (https=)
UA (1) UA94477C2 (https=)
WO (1) WO2008044109A1 (https=)
ZA (1) ZA200902481B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2658478C (en) 2006-07-20 2018-02-13 University Of Rochester Synthetic lung surfactant and use thereof
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
CN101948526B (zh) * 2010-09-02 2012-12-05 华东理工大学 一种肺泡表面活性蛋白质(sp-b和sp-c)的分离纯化方法
US9815869B2 (en) 2012-02-09 2017-11-14 University Of Rochester SP-B and SP-C peptides, synthetic lung surfactants, and use thereof
US20130303726A1 (en) * 2012-04-17 2013-11-14 Chiesi Farmaceutici S.P.A. Method for the preparation of surfactant peptides
AR093569A1 (es) 2012-11-21 2015-06-10 Chiesi Farm Spa Tensioactivos pulmonares reconstituidos
US10717777B2 (en) 2015-12-17 2020-07-21 The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Synthetic lung surfactant with enhanced stability and effectiveness
CA3016810C (en) 2016-03-07 2024-04-02 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Compositions and methods for administering ppar.gamma. agonists, surfactant peptides and phospholipids
RU2748417C2 (ru) 2016-08-24 2021-05-25 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Стабильная фармацевтическая композиция, включающая восстановленную композицию легочного сурфактанта
EP4097128A1 (en) 2020-01-28 2022-12-07 Chiesi Farmaceutici S.p.A. Polypeptides having improved properties
EP4228691A4 (en) * 2020-10-16 2025-01-01 Biosuperior Technology, Inc. PULMONARY TREATMENT COMPOSITIONS
WO2025024609A1 (en) * 2023-07-25 2025-01-30 Biosuperior Technology, Inc. Polypeptides for lung surfactant compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1340060A (zh) * 1999-02-12 2002-03-13 奇斯药制品公司 具有表面活性的人造肽及其在制备人造表面活性物质中的用途
CN1809338A (zh) * 2003-05-30 2006-07-26 奇斯药制品公司 用于合成性表面活性剂的新颖的脂质混合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001164A1 (en) * 1993-06-30 1995-01-12 Genentech, Inc. Method for preparing liposomes
US7065342B1 (en) * 1999-11-23 2006-06-20 Gofigure, L.L.C. System and mobile cellular telephone device for playing recorded music
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
CA2658478C (en) * 2006-07-20 2018-02-13 University Of Rochester Synthetic lung surfactant and use thereof
EP1997502A1 (en) * 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1340060A (zh) * 1999-02-12 2002-03-13 奇斯药制品公司 具有表面活性的人造肽及其在制备人造表面活性物质中的用途
CN1809338A (zh) * 2003-05-30 2006-07-26 奇斯药制品公司 用于合成性表面活性剂的新颖的脂质混合物

Also Published As

Publication number Publication date
EP2078038B1 (en) 2013-11-20
HK1134497A1 (en) 2010-04-30
CY1114716T1 (el) 2016-10-05
US20100004173A1 (en) 2010-01-07
MEP12109A (en) 2011-12-20
CA2666344C (en) 2017-04-18
PE20081184A1 (es) 2008-09-26
MX343064B (es) 2016-10-24
AU2007306075B2 (en) 2012-08-09
DK2078038T3 (da) 2013-12-02
PL2078038T3 (pl) 2014-05-30
KR20090083892A (ko) 2009-08-04
PT2078038E (pt) 2013-12-12
CN101522711A (zh) 2009-09-02
GEP20125531B (en) 2012-05-25
BRPI0715317B1 (pt) 2021-10-05
AR113422A2 (es) 2020-04-29
ES2438727T3 (es) 2014-01-20
EA200900373A1 (ru) 2009-10-30
HRP20140052T1 (hr) 2014-02-28
US8183210B2 (en) 2012-05-22
AR063263A1 (es) 2009-01-14
NZ576189A (en) 2011-09-30
CN103169947B (zh) 2014-10-29
CO6400235A2 (es) 2012-03-15
JP2013241449A (ja) 2013-12-05
JP5405307B2 (ja) 2014-02-05
CA2666344A1 (en) 2008-04-17
MX2009003638A (es) 2009-04-22
MA31062B1 (fr) 2010-01-04
CN103169947A (zh) 2013-06-26
HK1185274A1 (en) 2014-02-14
IL198075A0 (en) 2011-08-01
JP2010505937A (ja) 2010-02-25
KR101328851B1 (ko) 2013-11-14
JO2963B1 (en) 2016-03-15
WO2008044109A1 (en) 2008-04-17
ZA200902481B (en) 2010-07-28
TN2009000099A1 (en) 2010-08-19
NO20091441L (no) 2009-06-23
ME02326B (me) 2016-06-20
UA94477C2 (ru) 2011-05-10
AU2007306075A1 (en) 2008-04-17
RS53172B (sr) 2014-06-30
US9238058B2 (en) 2016-01-19
CL2007002931A1 (es) 2008-03-24
TW200824705A (en) 2008-06-16
TWI388333B (zh) 2013-03-11
EA015802B1 (ru) 2011-12-30
BRPI0715317A2 (pt) 2013-07-09
IL198075A (en) 2016-04-21
US20130079275A1 (en) 2013-03-28
NO342038B1 (no) 2018-03-19
MY148127A (en) 2013-02-28
EP2078038A1 (en) 2009-07-15
SI2078038T1 (sl) 2014-02-28

Similar Documents

Publication Publication Date Title
CN101522711B (zh) 具有改进性质的重组表面活性剂
CN101687006B (zh) 具有改善特性的重建表面活性剂
AU2008286026B2 (en) Synthetic pulmonary surfactant peptides
HK1134497B (en) Reconstituted surfactants having improved properties
HK1185274B (en) Reconstituted surfactants having improved properties
HK1144435A (en) Synthetic pulmonary surfactant peptides
HK1140420B (en) Reconstituted surfactants having improved properties

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1134497

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1134497

Country of ref document: HK