CN101518632A - Traditional Chinese medical tablet - Google Patents

Abstract

The invention discloses a traditional Chinese medical tablet, which is made from 11 kinds of raw traditional Chinese medicinal materials, namely, rhubarb, fructus cannabis, bunge cherry seed, bitter apricot seed, magnolia officinalis, dwarf lilyturf root, malt, szechuan lovage rhizome, largehead atractylodes rhizome, immature bitter orange and tangerine peel according to certain weight ratio. Effective components are extracted and the tablet is obtained through processing techniques such as concentration, drying, crushing, etc. The traditional Chinese medical tablet has high function of relaxing the bowels, is used for treating various symptoms of constipation, evacuation of dry and hardened or sticky feces, difficult evacuation of feces and the like, and is safe without toxicity and side effect for long period of taking.

Description

A kind of Chinese medicinal tablet that is used for constipation

Technical field

The present invention relates to the Chinese medicine preparation technical field, what be specifically related to is a kind of Chinese medicinal tablet that is used for constipation.

Technical background

Constipation is " symptom ", is again " commonly encountered diseases ".It is modal symptom of digestive tract, is meant obstructed, the infrequent defecation time lengthening of being hard and dry, or thinks stool and the discharge difficulty.Think that medically following three kinds of situations all belong to the category of constipation: the one, to be hard and dry, defecation frequency reduces, the infrequent defecation time lengthening; The 2nd, defecation frequency does not reduce, but it is hard to be hard and dry, difficult defecation; The 3rd, stool is also moist, but difficult defecation.You may not expect that there is the constipation problem in ten philtrums with regard to a people is arranged.According to incompletely statistics, have 20% people to suffer from various degree constipation approximately in China, and in old people and women colony, the constipation sickness rate is up to 40%.Influence that constipation caused and harm have caused showing great attention to of medical circle.

Etiology and pathogenesis to constipation in the theory of Chinese medical science is thought: diet is gone into stomach, through transporting and transforming function of the spleen and stomach, absorbs after its elite, and last waste matter transmits and goes out from large intestine at last, forms stool.Gastrointestinal function is normal, then free movement of the bowels; Gastrointestinal is subjected to disease, and as dryness-heat stagnating in the interior, or the stagnation of QI is not all right, or deficiency of vital energy transmission is unable, and the blood deficiency intestinal is dry and astringent, and stagnation of YIN-cold etc., can both cause various constipation of different nature.Though it is not normal that constipation belongs to the large intestine conduction function, very confidential relation is also arranged with taste and kidney.The cause of disease that causes constipation has dryness-heat stagnating in the interior, deficiency of body fluid; Abnormal emotion, depression and stagnation of QI; And the overstrain internal injury, health is weak, insufficiency of vital energy and blood etc.

Constipation is said and is not really serious disease, but has a strong impact on people's quality of life, brings many worries to the people.For constipation relieving, many people will eat a little cathartics easily, but inappropriate medication, the constipation problem not only can become and more and more bother, and also a series of untoward reaction may occur.

The medicine of the treatment constipation of using clinically has at present: osmotic laxative, irritant laxative, emollient laxative, permeability caccagogue, dynamics-promoting medicine and 5 one HT4 receptor stimulating agents etc.Osmotic laxative is also referred to as Epsom salts, because of it is not absorbed by intestinal wall and water-soluble, so can absorb large quantity of moisture in intestinal, the capacity of stool is increased, and plays the catharsis effect.The main representative medicine of such cathartic is a magnesium sulfate.But because it can not make colon tension force increase, so should not be used for the slow patient of those intestinal movements.

Cathartic also is a kind of more common emplastic.Some is the medicine that treats constipation originally, and they reach diarrhea inducing, relieving constipation purpose by different mechanism.But if this type of medicine of life-time service, intestinal movement forms the dependence to " foreign aid ", and the autonomic movement ability weakens, in case interrupt " foreign aid ", intestinal is difficult to recover in a short time autonomous dynamic, generation constipation as a result.This kind constipation is of common occurrence clinically, and most constipation person there is no and knows.From the angle of prevent constipation, the application of cathartic with " interim, be interrupted, alternately " for well.

Chinese medicinal tablet of the present invention from causing the cause of disease of constipation, is gone to the root of, and can effectively treat various constipation, the disease and take for a long time safely, have no side effect such as be clamminess, defecation is not smooth of being hard and dry, defecating.

Summary of the invention

The object of the invention is to provide a kind of Chinese medicinal tablet that is used for constipation, and its formula combination and preparation technology have been done correlational study.

Be achieved through the following technical solutions order of the present invention:

1, the present invention is made by the following weight proportion raw material:

40-200 parts of 40-200 parts of Semen Prunis of 40-200 parts of Fructus Cannabiss of Radix Et Rhizoma Rhei

30-150 parts of 40-200 parts of Cortex Magnoliae Officinalis of Semen Armeniacae Amarum 30-150 parts of Radix Ophiopogonis

30-150 parts of 40-200 parts of Rhizoma Atractylodis Macrocephalaes of 30-150 parts of Rhizoma Chuanxiongs of Fructus Hordei Germinatus

40-200 parts of 30-150 parts of Pericarpium Citri Reticulataes of Fructus Aurantii Immaturus

2, each raw material weight proportioning of optimum formula of the present invention is:

100 parts of 100 parts of Semen Prunis of 120 parts of Fructus Cannabiss of Radix Et Rhizoma Rhei

120 parts of 80 parts of Cortex Magnoliae Officinalis of Semen Armeniacae Amarum 80 parts of Radix Ophiopogonis

80 parts of 100 parts of Rhizoma Atractylodis Macrocephalaes of 120 parts of Rhizoma Chuanxiongs of Fructus Hordei Germinatus

120 parts of 80 parts of Pericarpium Citri Reticulataes of Fructus Aurantii Immaturus

3, preparation technology:

(1) gets Radix Et Rhizoma Rhei (coarse powder),, make solvent with 60% ethanol according to the percolation (appendix I O) under fluid extract and the extractum item, flood after 24 hours, with the speed of per minute 1～3ml percolation slowly, it is an amount of to collect the liquid of just filtering, in addition device is preserved, and continues percolation, to the percolate color light till, collect the continuous liquid of filtering, be concentrated into the thick paste shape, add the liquid of just filtering, mixing, leaves standstill to an amount of with 60% ethanol dilution, wait to clarify the back and filter, promptly get Extractum Rhei Liquidum;

(2) all the other the ten flavor Chinese crude drugs such as Fructus Cannabis of getting fire decoct with water three times, and each 1～2 hour, add 10～12 times of amounts of water for the first time, add 8～10 times of amounts of water for the second time, add 8～10 times of amounts of water for the third time, filter, merging filtrate is condensed into thick paste;

(3) Extractum Rhei Liquidum is added in the above-mentioned thick paste, mix homogeneously, the water bath method solvent, cold drying is ground into fine powder, sieve, adding starch is an amount of, and mixing with 85～95% alcohol granulations, adds 0.4～0.8% magnesium stearate, mixing, compacting wrap film-coat or sugar-coat, promptly in flakes.

Chinese medicine of the present invention, it be by pure Chinese crude drug according to certain weight proportion, the tablet that behind effective component extracting, take to concentrate, processes such as drying, pulverizing forms.This Chinese medicinal tablet has stronger function of relaxing bowel, is used for the treatment of various constipation, the disease such as be clamminess, defecation is not smooth of being hard and dry, defecating, and takes safe without toxic side effect for a long time.

The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.

The specific embodiment

Embodiment 1:

Prescription is formed:

Radix Et Rhizoma Rhei 120g Fructus Cannabis 100g Semen Pruni 100g

Semen Armeniacae Amarum 80g Cortex Magnoliae Officinalis 80g 120g Radix Ophiopogonis

Fructus Hordei Germinatus 120g Rhizoma Chuanxiong 100g Rhizoma Atractylodis Macrocephalae 80g

Fructus Aurantii Immaturus 80g Pericarpium Citri Reticulatae 120g

Preparation technology:

(1) gets Radix Et Rhizoma Rhei (coarse powder) 120g,, make solvent with 60% ethanol according to the percolation (appendix I O) under fluid extract and the extractum item, flood after 24 hours,, collect the liquid 90ml that just filters with the speed of per minute 1～3ml percolation slowly, in addition device is preserved, and continues percolation, to the percolate color light till, collect the continuous liquid of filtering, be concentrated into the thick paste shape, add the liquid of just filtering, mixing, leaves standstill to 120ml with 60% ethanol dilution, wait to clarify the back and filter, promptly get Extractum Rhei Liquidum;

(2) all the other the ten flavor Chinese crude drugs such as Fructus Cannabis of getting fire decoct with water three times, and each 1.5 hours, add 12 times of amounts of water for the first time, add 10 times of amounts of water for the second time, add 8 times of amounts of water for the third time, filter, merging filtrate is condensed into thick paste;

(3) Extractum Rhei Liquidum is added in the above-mentioned thick paste, mix homogeneously, the water bath method solvent, cold drying is ground into fine powder, sieves, and adding starch is an amount of, and mixing is used 95% alcohol granulation, adds 0.6% magnesium stearate, mixing, compacting is wrapped film-coat, promptly in flakes.

Embodiment 2:

Prescription is formed:

Radix Et Rhizoma Rhei 80g Fructus Cannabis 60g Semen Pruni 60g

Semen Armeniacae Amarum 40g Cortex Magnoliae Officinalis 40g 80g Radix Ophiopogonis

Fructus Hordei Germinatus 80g Rhizoma Chuanxiong 60g Rhizoma Atractylodis Macrocephalae 40g

Fructus Aurantii Immaturus 40g Pericarpium Citri Reticulatae 80g

Preparation technology:

(1) gets Radix Et Rhizoma Rhei (coarse powder) 80g,, make solvent with 60% ethanol according to the percolation (appendix I O) under fluid extract and the extractum item, flood after 24 hours,, collect the liquid 65ml that just filters with the speed of per minute 1～3ml percolation slowly, in addition device is preserved, and continues percolation, to the percolate color light till, collect the continuous liquid of filtering, be concentrated into the thick paste shape, add the liquid of just filtering, mixing, leaves standstill to 80ml with 60% ethanol dilution, wait to clarify the back and filter, promptly get Extractum Rhei Liquidum;

(2) all the other the ten flavor Chinese crude drugs such as Fructus Cannabis of getting fire decoct with water three times, and each 1 hour, add 10 times of amounts of water for the first time, add 8 times of amounts of water for the second time, add 8 times of amounts of water for the third time, filter, merging filtrate is condensed into thick paste;

(3) Extractum Rhei Liquidum is added in the above-mentioned thick paste, mix homogeneously, the water bath method solvent, cold drying is ground into fine powder, sieves, and adding starch is an amount of, and mixing is used 90% alcohol granulation, adds 0.5% magnesium stearate, mixing, compacting is in blocks, sugar coating, promptly.

Embodiment 3:

Prescription is formed:

Radix Et Rhizoma Rhei 160g Fructus Cannabis 140g Semen Pruni 140g

Semen Armeniacae Amarum 120g Cortex Magnoliae Officinalis 120g 160g Radix Ophiopogonis

Fructus Hordei Germinatus 160g Rhizoma Chuanxiong 140g Rhizoma Atractylodis Macrocephalae 120g

Fructus Aurantii Immaturus 120g Pericarpium Citri Reticulatae 160g

Preparation technology:

(1) gets Radix Et Rhizoma Rhei (coarse powder) 160g,, make solvent with 60% ethanol according to the percolation (appendix I O) under fluid extract and the extractum item, flood after 24 hours,, collect the liquid 140ml that just filters with the speed of per minute 1～3ml percolation slowly, in addition device is preserved, and continues percolation, to the percolate color light till, collect the continuous liquid of filtering, be concentrated into the thick paste shape, add the liquid of just filtering, mixing, leaves standstill to 160ml with 60% ethanol dilution, wait to clarify the back and filter, promptly get Extractum Rhei Liquidum;

(2) all the other the ten flavor Chinese crude drugs such as Fructus Cannabis of getting fire decoct with water three times, and each 2 hours, add 12 times of amounts of water for the first time, add 10 times of amounts of water for the second time, add 10 times of amounts of water for the third time, filter, merging filtrate is condensed into thick paste;

(3) Extractum Rhei Liquidum is added in the above-mentioned thick paste, mix homogeneously, the water bath method solvent, cold drying is ground into fine powder, sieves, and adding starch is an amount of, and mixing is used 90% alcohol granulation, adds 0.8% magnesium stearate, mixing, compacting is in blocks, sugar coating, promptly.

Claims (3)

1, a kind of Chinese medicinal tablet that is used for constipation is characterized in that it comprises what weight was made by the following raw material of part:

40-200 parts of 40-200 parts of Semen Prunis of 40-200 parts of Fructus Cannabiss of Radix Et Rhizoma Rhei

30-150 parts of 40-200 parts of Cortex Magnoliae Officinalis of Semen Armeniacae Amarum 30-150 parts of Radix Ophiopogonis

30-150 parts of 40-200 parts of Rhizoma Atractylodis Macrocephalaes of 30-150 parts of Rhizoma Chuanxiongs of Fructus Hordei Germinatus

40-200 parts of 30-150 parts of Pericarpium Citri Reticulataes of Fructus Aurantii Immaturus.

2, a kind of Chinese medicinal tablet that is used for constipation as claimed in claim 1 is characterized in that the weight proportion of each component is:

100 parts of 100 parts of Semen Prunis of 120 parts of Fructus Cannabiss of Radix Et Rhizoma Rhei

120 parts of 80 parts of Cortex Magnoliae Officinalis of Semen Armeniacae Amarum 80 parts of Radix Ophiopogonis

80 parts of 100 parts of Rhizoma Atractylodis Macrocephalaes of 120 parts of Rhizoma Chuanxiongs of Fructus Hordei Germinatus

120 parts of 80 parts of Pericarpium Citri Reticulataes of Fructus Aurantii Immaturus.

3, a kind of Chinese medicinal tablet that is used for constipation as claimed in claim 1 is characterized in that the preparation technology of this Chinese medicinal tablet is:

(1) gets Radix Et Rhizoma Rhei (coarse powder),, make solvent with 60% ethanol according to the percolation (appendix I0) under fluid extract and the extractum item, flood after 24 hours, with the speed of per minute 1～3ml percolation slowly, it is an amount of to collect the liquid of just filtering, in addition device is preserved, and continues percolation, to the percolate color light till, collect the continuous liquid of filtering, be concentrated into the thick paste shape, add the liquid of just filtering, mixing, leaves standstill to an amount of with 60% ethanol dilution, wait to clarify the back and filter, promptly get Extractum Rhei Liquidum;

(2) all the other the ten flavor Chinese crude drugs such as Fructus Cannabis of getting fire decoct with water three times, and each 1～2 hour, add 10～12 times of amounts of water for the first time, add 8～10 times of amounts of water for the second time, add 8～10 times of amounts of water for the third time, filter, merging filtrate is condensed into thick paste;

(3) Extractum Rhei Liquidum is added in the above-mentioned thick paste, mix homogeneously, the water bath method solvent, cold drying is ground into fine powder, sieve, adding starch is an amount of, and mixing with 85～95% alcohol granulations, adds 0.4～0.8% magnesium stearate, mixing, compacting wrap film-coat or sugar-coat, promptly in flakes.