CN101518629A - Traditional Chinese medicine composition for treating asthma and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating asthma; the traditional Chinese medicine composition is prepared from ephedrae herb, almond, bulbus fritilariae, polygala root, platycodon root, liquorice, ginkgo seed, caladium, platycladi seed, radix asteris, rhizoma pinelliae preparata, coix seed, jujube kernel, cacumen platycladi, cornus, Chinese mugwort leaf and/or carriers which are acceptable pharmaceutically. The invention also relates to a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition has therapeutic effects of stopping cough, eliminating phlegm, removing heat and antisepticising and is mainly used for stopping cough, eliminating phlegm and relieving asthma.

Description

A kind of antasthmatic Chinese medicine composition and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition, specifically, relate to a kind of antasthmatic Chinese medicine composition and preparation method thereof.

Background technology

Bronchial asthma is called for short asthma, is a kind of ancient disease.Since the later stage eighties 20th century, along with the constantly dark people of people to asthma research, this essence of asthma air flue chronic nonspecific inflammation is revealed gradually comes out, generally believe at present: bronchial asthma is a kind of chronic inflammatory airway disease, wherein many cells work, particularly mastocyte, eosinophilic granulocyte and T lymphocyte.In Susceptible population, this inflammation can cause repeatedly the panting of outbreak, dyspnea, uncomfortable in chest and cough, especially night and (or) early morning.These symptoms are relevant with extensive but different flow limitations usually, and flow limitation spontaneously or after treatment can partly reverse at least.Inflammation also can cause the reactive enhancing of air flue to different stimulated.

The formation of bronchial asthma is relevant with several factors with outbreak, thereby shows as clinically: in the same environment, some suffer from bronchial asthma and other people are normal; Same asthmatic patient, the asthma of frequently showing effect under certain conditions, in another environment then as the normal person.This mainly is owing to cause the asthma factor (factor) and the short asthma factor (factor) two big class factors determine.Some factor all plays a role in the generation of asthma, development.

Bronchial asthma is a kind of airway inflammation disease of cause of disease complexity, and its Clinical symptoms is airway hyperreactivity and bronchospasm.The symptom of bronchospasm takes place during asthma attack, shows as clinically and pants, cough, expectoration, breathes hard and uncomfortable in chest or symptoms such as breast tight, dyspnea and chest pain.The asthma attack of part asthmatic patient has inducement, as the stimulation of contact allergen, viral respiratory tract infection, motion and other motivating factor etc.The omen of asthma attack occurs bronchial asthma attack forward part patient, for example dyspnea and cough take place in the motion back, rise in night and morning uncomfortable in chest etc.The acute asthma outbreak that causes at allergen is gone to toward the mucositis symptom that nose and eyes mucosa are arranged, and as rhinocnesmus, sneeze, watery nasal discharge, ophthalmic pruritus, shed tears and dry cough etc., typical symptoms of asthma then occurs.Asthma attack at most of asthmatic patients is unexpected, and through outbreak repeatedly for many years, the state of an illness can increase the weight of gradually, pants to be chronic lasting outbreak.Bronchial asthma is a kind of chronic respiratory tract disease, and the medical history of outbreak is repeatedly often arranged for many years.The classical symptom of bronchial asthma be the cough, uncomfortable in chest, pant and dyspnea.Different patients has the symptom performance of various combination, and the order of severity is also different.Cough may be because inflammatory mediator has stimulated sensory nerve, it is the symptom of cough variant asthma and childhood asthma particular importance, uncomfortable in chest and the most likely flow limitation of panting causes, dyspnea is likely that the change of the active enhancing of increase, respiratory muscle, lung compliance of reflection work of breathing and relevant inflammatory mediator are directly to the stimulation of nerve.

The asthma of Chinese medicine indication contains two kinds of broad sense and narrow senses, and generalized asthma comprises the symptom of panting that is caused by multiple diseases such as heart, lungs, i.e. 〃 the syndrome of dyspnea 〃 of the traditional Chinese medical science; The asthma of narrow sense is meant bronchial asthma, also is the 〃 asthma 〃 of the traditional Chinese medical science.Roaring and breathe heavily class mutually, is that the sound of sipping (wheezing sound) is arranged in larynx and the lung but roar, and 〃 asthma 〃 is a card with wheezing in sudden onset, rapid breathing, the larynx, rough, failing to lie flat due to dyspnea uncomfortable in chest usually.The traditional Chinese medical science thinks that the cause of disease of asthma is because the natural endowment deficiency.Visceral dysfunction causes lying prostrate in the retained phlegm in patient's Yu lung, again by exopathogen invasion, drinking and eating irregularly, changes in temperature are improper or feelings will is not smooth etc. outer thereby bring out.Also have because of the ground person of forming that occupies cold-damp for a long time or by Yu Ercheng person in long-pending hot smoking steaming, the phlegm-fire.The acute attack stage of asthma is real to mark usually.And the asthma catabasis is many based on deficiency in origin, and prolonged illness shows effect repeatedly then can cause the deficiency syndrome of lung, kidney, spleen, shows as the feature of simulataneous insufficiency and excessive, deficiency in origin and excess in superficiality.The determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs of asthma should be observed radical treatment in chronic case, anxious then control its table 〃 principle.

The endogenous cause of ill of one asthma (perennial root)

By the natural endowment deficiency, visceral dysfunction causes retained phlegm to stop gathering patient's Yu lung meridian, and phlegm-damp or expectorant heat lie prostrate in patient's Yu lung, and become the perennial root of asthma.This is that patient easily experiences exopathogen, brings out the immanent cause of asthma.During asthma attack, heresy is contained in lung, but the root of disease is then relevant with kidney and spleen.This is to take charge of breathing because of lung governing qi, but gas at all at kidney, suffering from a deficiency of the kidney then can not improving inspiration by invigorating kidney-QI, causes the handing-over of purgation gas not normal." Lei Zheng Zhi Cai " alleged 〃 the lung being the dominator of QI, the kidney being the root of QI, lung the master give vent to anger.Kidney governing inspiration.Negative and positive intersect, breathing be and, if cashier's abnormal ascending-descending of QI, here this breathes heavily work.〃 has illustrated the 〃 lung governing qi, and kidney improving inspiration by invigorating kidney-QI, gas be the substantial connection of root between the lung kidney of kidney 〃 for lung, and the dialectical of asthma patient also can common deficiency of kidney-QI person.Lung is the device 〃 of 〃 storage expectorant, and spleen is the source 〃 that 〃 gives birth to expectorant, if dysfunction of the spleen in transportation, then poly-liquid becomes expectorant, on hinder in lung and cause asthma, (card is controlled gains in depth of comprehension〉cloud: 〃 the lung being the dominator of QI, spleen then lung mother also.The spleen lung has that to lose then gasification not enough, and deficiency is then very brief and breathe heavily.〃 is wherein especially with the prosperity and decline of kidney qi, more plays an important role for the advance and retreat of primary disease.. expectorant also is a key factor of asthma morbidity, and why repeatedly primary disease outbreak, how to trigger because of there being latent phlegm to meet inducement.The source of expectorant mainly contains three, one because of insufficiency of the spleen, and the malfunction of transmitting and distributing the fluids, water wet and stop gathering into expectorant; Two because of kidney yang deficiency.Inability of water to function, going up general is expectorant; The three categories of etiologic factors insufficiency of lung-QI respectfully falls dereliction of duty, also can give birth to expectorant.Because of there being phlegm-damp to stop gathering, so in case triggered by inducement, with regard to pneumatic expectorant liter, mental disorder is fought mutually, deficient airway, breathing is obstructed, and the septum pectorale feeling of distension and oppression occurs, wheezing sound is arranged in the larynx, breath with cough and can not equal the symptom that air flue such as for sleeping in is jammed.Some patient promptly sends out asthma since the childhood, and this asthma and sick child's interior latent phlegm drink (perennial root) is in close relations, is referred to as 〃 days heavy breathing 〃 clinically.

The exopathogenic factor of two asthma

Exopathogenic factor also is the principal element of bringing out asthma.The patient who has retained phlegm to stop gathering at lung meridian.Can cause pneumatic expectorant liter during being invaded by exogenous pathogen, block the lung network, and cause the rale dyspnea.The exopathogenic factor of asthma mainly contains following several:

(1) exopathogen that is affected by the cold,

The exopathogenic factor of asthma is in the majority with the heresy of wind and cold, and especially the variation with weather has substantial connection.Change cold as temperature, be affected by the cold and cause.With the passing of time evil touching outside the wind and cold, heresy lies prostrate in the lining, stays in fei shu to cause a disease.

(2) improper diet

Many foods can cause bronchial wheezing, as fish shrimp crab class, clam class, bivalves and shellfish marine product, milk, egg, meat products, bean product, Semen Sesami, Semen arachidis hypogaeae, Seem Lablab Album, Semen Phaseoli Vulgaris, Fructus Persicae, Fructus Musae, Fructus Mali pumilae, chocolate and maror, cross into sweet food thing etc. all can cause or aggravate patient's condition.

(3) occupy the ground of cold-damp for a long time

The ground person of forming who occupies cold-damp for a long time be the factor body this lose, form bronchial wheezing, occupy the ground of cold humidity for a long time and aggravate, meet warm and the person of being recovered.

(4) experience pathogenic fire

Hot summer days, aversion to heat is aversion to cold not during intenseness of heat and send out whenever, and expectorant is shouted dyspnea with rapid respiration, irritated xerostomia.Experience pathogenic fire and cause the heavy breathing patient usually in morbidity or patient's condition aggravation in summer.

(5) abnormal emotion

Happiness, anger, melancholy, think of, compassion, probably, the seven emotions of spiritual feelings will such as frightened change the function that can influence the internal organs QI and blood, many asthma patients can cause the outbreak of panting because of the change of these spirit, emotional factor, this is comparatively obvious the adult patient.

(6) overworked

Health overtired, impairment of the lung caused by overstrain, impairment of the kidney caused by overstrain, the impairment of the spleen due to overstrain and the impairment of the heart caused by overstrain, hepatic asthenia all can influence the function of internal organs in various degree, are one of exopathogenic factors that causes asthma.

The differentiation of symptoms and signs for classification of syndrome of three bronchial asthmas

Asthma is a kind of chronic disease of outbreak repeatedly, and its Therapeutic Method can have bigger difference because of stage of attack and paracmastic syndrome different.The traditional Chinese medical science should at first be distinguished the deficiency and excess of asthma to treatment of asthma; According to deficiency and excess, dyspnea due to deficiency carefully distinguish again belong to the deficiency of the lung, suffer from a deficiency of the kidney, insufficiency of the spleen.Be the yang deficiency or the deficiency of YIN.Excess-dyspnea distinguishes carefully that again belonging to dyspnea due to cold still belongs to dyspnea of heat type, and notes holding concurrently mutually and transforming of cold and heat.Except that the syndrome of distinguishing the deficiency and excess cold and heat, also must carefully distinguish to have or not expectorant to stop up.It is generally acknowledged that acute asthma how true card of stage of attack mainly shows as sudden onset, chest and diaphragm is full vexed, and rapid breathing has wheezing sound in the larynx, and prolonged expiration has been forced to seat, must not put down for sleeping in, visible pale complexion of weight person or cyanosis, dripping sweat.The asthma catabasis deficiency syndrome that belong to more.But author's simulataneous insufficiency and excessive is sent out in prolonged illness repeatedly.

(1) excess-dyspnea

(2) excess-dyspnea mainly occurs in the asthma acute stage, shows as mainly that gurgling with sputum, sound pitch are rough, dyspnea, dysphoria, two bluish lip purples, asthma is low voice speaking etc., is mainly wind and cold or hot-tempered heat and violates lung, phlegm-damp stops gathering in addition, due to QI rising in reverse order expectorant rose, comparatively common, excess-dyspnea had the branch of dyspnea due to cold and dyspnea of heat type.

1. dyspnea due to cold mainly shows as rapid breathing, gurgling with sputum, fear of cold is lossless, the back of the body is cold, sneeze, snivel, and limbs are not warm, pale complexion, the thirsty or desire for hot drinks of clear and thin sputum and be with foam, mouth, clear urine in large amounts, loose stool, pale tongue with thin fur is white or white greasy, stringy and thready pulse or slick and frivolous.If with the aversion to cold aversion to wind, fever without perspiration, the headache general pain, the floating and tense pulse person is for having exterior syndrome due to wind-cold concurrently.Modern medicine typically refers to the simple asthma attack that dyspnea due to cold infects for the apnea road.

2. to show as mainly that To Be Protected from Heat irritated for dyspnea of heat type, and the face lip is redder, sound pitch raucous breath during asthma attack, gurgling with sputum, laryngalgia.Thick sputum and Huang, thirst and liking cold drink, oliguria with reddish urine.Constipation with dry stool, red tongue with yellowish and greasy fur, slippery and rapid pulse.If the companion sees that heating spontaneous perspiration person is for having the wind heat exterior syndrome concurrently.Modern medicine it has been generally acknowledged that dyspnea of heat type is the bronchial asthma in acute attack that merges respiratory tract infection.

(2) dyspnea due to deficiency

The paracmastic main syndrome of asthma is deficiency syndrome, mainly shows as sensation of oppression over the chest with shortness of breath, and is moving then out of breath, and sound is little though breathe heavily, cough with copious phlegm etc.Mainly with the deficiency of the lung, insufficiency of the spleen or suffer from a deficiency of the kidney relevant.Should carefully carry out dialectically, give methods such as lung benefiting, spleen invigorating, the kidney invigorating respectively.

1. the deficiency of the lung is many by due to cloudy two wounds of gas after the exterior syndrome.Since the lung being the dominator of QI, therefore main performance fear of cold spontaneous perspiration, and cough is breathed hard.Abundant expectoration is rare clearly, and voice are low, lazy speech, and the complexion Mental fatigue is felt wind and cold slightly, brings out asthma easily, and premorbid sneeze, nasal obstruction, snivel, pale tongue with thin fur are white, the genus insufficiency of lung-QI that relaxed and soft pulse is unable; If breathe hard cough, lack expectorant or do not have expectorant.Dry mouth and throat, feverish sensation in the palms and soles, afternoon flushed cheeks or hectic fever, tender few tongue of red tongue or no fur, the genus deficiency of lung-YIN of thready and rapid pulse.

2. insufficiency of the spleen many because of exopathogen invasion or the polyphagia raw food or the peppery dysfunction of the spleen that causes, give birth in expectorant is turbid and uply cause in lung.Mainly show as cough with copious phlegm, the face Huang Shaohua.Fatigue and weakness, inappetence, abdominal distention after meal, big loose stool is thin, the greasy then easy diarrhea or see edema of edible oil.The pale tongue with white fur profit, moderate pulse or carefully unable.

3. the deficiency of kidney-QI of suffering from a deficiency of the kidney is the most common at asthmatic patient, and suffering from a deficiency of the kidney often can be through the whole generation evolution of asthma.Be that prolonged illness is impairment of the kidney, the loss of kidney unit. kidney qi is lost and is received and cause.It is short to show as the breath of breathing hard.Exhale inhale few, activity more so, cardiopalmus is told frothy sputum, waist soreness.Insufficiency of kidney-YANG shows as weakness due to chronic disease, fear of cold, dyspnea while acting, soreness of waist tinnitus.Spontaneous perspiration.Hands and feet being not warm, pale complexion, clear urine in large amounts or frequent urination at night, the tender white and moist fur of light red tongue, deep,thready and forceless pulse; Deficiency of the kidney yin shows as dizziness and tinnitus, dysphoria with feverish sensation in the chest palms and soles, and the few thickness of expectorant.Dry mouth and throat, the big dry stool of yellowish urine is become thin, night sweat, red tongue.Thready and rapid pulse.If both symptoms have concurrently, as aversion to cold and cold limbs, frequent urination at night, dizziness and tinnitus, feverish sensation in the palms and soles, the few tongue of red tongue.The thready and rapid pulse person belongs to kidney insufficiency.

The effecting a permanent cure and taking stopgap measures of four asthma

Chinese traditional treatment asthma is the same with its disease of treatment, also should follow the 〃 symptomatic treatment in acute condition, the principle of radical treatment in chronic case 〃, how true card when acute attack, to distinguish cold and heat earlier, control table to attack heresy, the asthma catabasis based on deficiency syndrome, then to carefully distinguish the deficiency and excess and the deficiency of YIN yang deficiency of lung, spleen, kidney. with strengthening the body resistance.But for many outbreak, touching chronic asthma patients of not healing treating both the principal and secondary aspects of a disease then repeatedly throughout the year.Give priority in the aspect of just should and taking stopgap measures aspect effecting a permanent cure.The stage of attack of asthma, is real to show, and the catabasis is then based on deficiency in origin.Then features that show as simulataneous insufficiency and excessive, deficiency in origin and excess in superficiality when prolonged illness shows effect repeatedly, the clinician should careful determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, just can grasp to take stopgap measures, effect a permanent cure and the principle for the treatment of both the principal and secondary aspects of a disease more.And face the critical type asthma attack of card diagnosis and treatment, when the collapse syndrome caused by dyspnea phenomenon occurring.Should cooperate multiple therapy methods, comprise the western medical treatment measure.

Diseases caused by exogenous pathogenic factor, retained phlegm are this for mark, deficiency of kidney-QI, failure of the kidney in receiving QI.Deficiency of kidney-QI and the failure of the kidney in receiving QI that causes of suffering from a deficiency of the kidney is that patient's retained phlegm forms, the main root of susceptible exogenous cold.Ming Dynasty doctor family has just proposed to control when 〃 sends out lung.Control the rule of treatment of kidney 〃 at ordinary times, having pointed out the kidney invigorating is the effect a permanent cure key of 〃 of asthma 〃.The kidney being the origin of congenital constitution, and the root of the five internal organs is so attach most importance to the kidney invigorating; This rule of treatment instructs down, and we are for the suitable treating both the principal and secondary aspects of a disease of chronic asthma patient, treating the lung and kidney simultaneously that outbreak, deficiency in origin and excess in superficiality repeatedly are mingled with, and reinforcement and elimination in combination, treating both the principal and secondary aspects of a disease should be from the integral body of tonify deficiency, and taking into account relievings asthma eliminates the phlegm, and makes to attack heresy and just do not hinder.Tonify deficiency is held concurrently eliminating evil, because asthma is a kind of difficult persistent ailment of thoroughly curing, the main purpose of effecting a permanent cure is to reduce attack times by 〃 strengthening the body resistance 〃 as far as possible.Make the asthma long-term remission, strive 〃 radical cure 〃.The measure of effecting a permanent cure should be carried out in the catabasis, according to different empty time of internal organs regulating YIN and YANG.The primary and secondary of difference lung, spleen, kidney is particularly attached most importance to the kidney invigorating, takes into account comprehensively.Retained phlegm also is one of asthma root, so also should control it at phlegm-damp.Effecting a permanent cure must long-term treatment, also should not cause in the catabasis at ordinary times.With advancing age.Contain kidney qi day, be equipped with and set upright gas and keep away the measure that effects a permanent cure such as exopathogen.Can reach the purpose of healing or long-term remission, it is main therefore should effecting a permanent cure to young asthmatic patient.Person in middle and old age's asthma then many because of the kidney qi degradation delay difficult, can treating both the principal and secondary aspects of a disease or to effect a permanent cure be main.The time no matter effect a permanent cure, take stopgap measures or treating both the principal and secondary aspects of a disease facing card, all should be according to dissimilar in addition determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, arrest in a side one medicine and often be difficult to receive satisfied curative effect.

Summary of the invention

The purpose of this invention is to provide a kind of antasthmatic Chinese medicine composition.

The present invention also aims to provide a kind of preparation method of this Chinese medicine composition.

In order to realize purpose of the present invention, the invention provides a kind of antasthmatic Chinese medicine composition, be to make by effective ingredient and/or pharmaceutically acceptable carrier, described effective ingredient is made by weight by following raw materials according:

Herba Ephedrae 6-9 part Semen Armeniacae Amarum 2-25 part Bulbus Fritillariae Cirrhosae 9-20 part

Radix Polygalae 3-12 part Radix Platycodonis 6-12 part Radix Glycyrrhizae 2-6 part

Semen Ginkgo 4-12 part Bulbus Fritillariae Uninbracteatae 4-12 part Semen Platycladi 9-18 part

Radix Asteris 6-12 part Rhizoma Pinelliae Preparatum 6-12 part Semen Coicis 2-12 part

Semen Ziziphi Spinosae 3-11 part Cacumen Platycladi 10-30 part Fructus Corni 6-12 part

-30 parts of Folium Artemisiae Argyi 10 grams

Effective ingredient is preferably made by weight by following raw materials according:

12 parts of 12 parts of Bulbus Fritillariae Cirrhosae of 7 parts of Semen Armeniacae Amarums of Herba Ephedrae

4 parts in 9 portions of Radix Glycyrrhizaes of 9 parts of Radix Platycodoniss of Radix Polygalae

12 parts of 8 parts of Semen Platycladi of 8 portions of Bulbus Fritillariae Uninbracteataes of Semen Ginkgo

6 parts of 8 parts of Semen Coiciss of 8 parts of Rhizoma Pinelliae Preparatum of Radix Asteris

9 parts of 12 parts of Fructus Corni of 9 portions of Cacumen Platycladis of Semen Ziziphi Spinosae

12 parts of Folium Artemisiae Argyis

The present invention also provides a kind of preparation method of this Chinese medicine composition, comprises the steps:

(1) Herba Ephedrae, Semen Armeniacae Amarum, Semen Platycladi, Semen Coicis, Semen Ziziphi Spinosae are ground into impalpable powder, and be standby;

(2) Bulbus Fritillariae Cirrhosae, Radix Polygalae, Radix Platycodonis, Radix Glycyrrhizae, Semen Ginkgo, Bulbus Fritillariae Uninbracteatae, Radix Asteris, Rhizoma Pinelliae Preparatum, Cacumen Platycladi, Fructus Corni, Folium Artemisiae Argyi decoct with water secondary, each 2 hours, filter merging filtrate, concentrating under reduced pressure, add ethanol to 65%, left standstill 48 hours, and got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder, make granule, capsule and tablet with pharmaceutically acceptable carrier.

Pharmaceutical composition of the present invention can with receivable carrier pharmaceutically, for example: filler such as starch, microcrystalline Cellulose etc.; Binding agent such as vitamin derivative, starch etc.; Mode by granule, capsule, tablet oral administration is used.

Chinese medicine composition of the present invention has eliminating phlegm and stopping cough, the antibiotic effect of heat clearing away, is mainly used in cough-relieving, eliminates the phlegm, relievings asthma.

The specific embodiment:

Following examples are used to illustrate the present invention, but are not used for limiting the scope of the invention.

Embodiment 1 Chinese medicinal composition granules of the present invention

(1) Herba Ephedrae, Semen Armeniacae Amarum, Semen Platycladi, Semen Coicis, Semen Ziziphi Spinosae are ground into impalpable powder, and be standby;

(2) Bulbus Fritillariae Cirrhosae, Radix Polygalae, Radix Platycodonis, Radix Glycyrrhizae, Semen Ginkgo, Bulbus Fritillariae Uninbracteatae, Radix Asteris, Rhizoma Pinelliae Preparatum, Cacumen Platycladi, Fructus Corni, Folium Artemisiae Argyi decoct with water secondary, each 2 hours, filter, merging filtrate, concentrating under reduced pressure adds ethanol to 65%, leaves standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density;

(3) add above-mentioned fine powder, drying under reduced pressure is ground into fine powder, adds dextrin 2000g, lactose 800g, mixing, with 75% ethanol wet granulation promptly.

Embodiment 2 Chinese medicinal composition capsules agent of the present invention

(1) Herba Ephedrae, Semen Armeniacae Amarum 1, Semen Platycladi, Semen Coicis, Semen Ziziphi Spinosae are ground into impalpable powder, and be standby;

(2) Bulbus Fritillariae Cirrhosae, Radix Polygalae, Radix Platycodonis, Radix Glycyrrhizae, Semen Ginkgo, Bulbus Fritillariae Uninbracteatae, Radix Asteris, Rhizoma Pinelliae Preparatum, Cacumen Platycladi, Fructus Corni, Folium Artemisiae Argyi decoct with water secondary, each 2 hours, filter, merging filtrate, concentrating under reduced pressure adds ethanol to 65%, leaves standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density;

(3) add above-mentioned fine powder, drying under reduced pressure is ground into fine powder, adds dextrin 700g mixing, in the capsulae vacuus of packing into promptly.

Embodiment 3 Chinese medicine composition tablets of the present invention

(1) Herba Ephedrae, Semen Armeniacae Amarum 1, Semen Platycladi, Semen Coicis, Semen Ziziphi Spinosae are ground into impalpable powder, and be standby;

(2) Bulbus Fritillariae Cirrhosae, Radix Polygalae, Radix Platycodonis, Radix Glycyrrhizae, Semen Ginkgo, Bulbus Fritillariae Uninbracteatae, Radix Asteris, Rhizoma Pinelliae Preparatum, Cacumen Platycladi, Fructus Corni, Folium Artemisiae Argyi decoct with water secondary, each 2 hours, filter, merging filtrate, concentrating under reduced pressure adds ethanol to 65%, leaves standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density;

(3) add above-mentioned fine powder, drying under reduced pressure is ground into fine powder, adds starch 300 microcrystalline Cellulose 200 with 70% ethanol wet granulation, and tabletting, coating are promptly.

Claims (4)

1, a kind of antasthmatic Chinese medicine composition is by effective ingredient and/or made in pharmaceutically acceptable year, it is characterized in that described effective ingredient is made by weight by following raw materials according:

Herba Ephedrae 6-9 part Semen Armeniacae Amarum 2-25 part Bulbus Fritillariae Cirrhosae 9-20 part

Radix Polygalae 3-12 part Radix Platycodonis 6-12 part Radix Glycyrrhizae 2-6 part

Semen Ginkgo 4-12 part Bulbus Fritillariae Uninbracteatae 4-12 part Semen Platycladi 9-18 part

Radix Asteris 6-12 part Rhizoma Pinelliae Preparatum 6-12 part Semen Coicis 2-12 part

Semen Ziziphi Spinosae 3-11 part Cacumen Platycladi 10-30 part Fructus Corni 6-12 part

-30 parts of Folium Artemisiae Argyi 10 grams.

2, Chinese medicine composition as claimed in claim 1 is characterized in that described effective ingredient made by weight by following raw materials according:

12 parts of 12 parts of Bulbus Fritillariae Cirrhosae of 7 parts of Semen Armeniacae Amarums of Herba Ephedrae

4 parts in 9 portions of Radix Glycyrrhizaes of 9 parts of Radix Platycodoniss of Radix Polygalae

12 parts of 8 parts of Semen Platycladi of 8 portions of Bulbus Fritillariae Uninbracteataes of Semen Ginkgo

6 parts of 8 parts of Semen Coiciss of 8 parts of Rhizoma Pinelliae Preparatum of Radix Asteris

9 parts of 12 parts of Fructus Corni of 9 portions of Cacumen Platycladis of Semen Ziziphi Spinosae

12 parts of Folium Artemisiae Argyis.

3,, it is characterized in that described Chinese medicine composition can be made into granule, capsule and tablet as the arbitrary described Chinese medicine composition of claim 1-2.

4, a kind of preparation method as the arbitrary described Chinese medicine composition of claim 1-3 comprises the steps:

(1) Herba Ephedrae, Semen Armeniacae Amarum, Semen Platycladi, Semen Coicis, Semen Ziziphi Spinosae are ground into impalpable powder;

(2) Bulbus Fritillariae Cirrhosae, Radix Polygalae, Radix Platycodonis, Radix Glycyrrhizae, Semen Ginkgo, Bulbus Fritillariae Uninbracteatae, Radix Asteris, Rhizoma Pinelliae Preparatum, Cacumen Platycladi, Fructus Corni, Folium Artemisiae Argyi decoct with water secondary, each 2 hours, filter merging filtrate, concentrating under reduced pressure, add ethanol to 65%, left standstill 48 hours, and got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder, make granule, capsule and tablet with pharmaceutically acceptable carrier.