CN101518625B - Drug for treating toxuria - Google Patents

Abstract

The invention discloses a drug for treating toxuria, which belongs to an oral herb medicament for treating kidney failure and toxuria. The drug comprises the following Chinese crude drugs by weight percent: 5 to 12 percent of cornu saigae tatariace powder, 4 to 8 percent of rhinoceros horn, 4 to 8 percent of polygonum, 4 to 8 percent of peach seed, 2 to 5 percent of manchurian wildginger, 2 to 5 percent of bletilla, 2 to 5 percent of ampelopsis, 5 to 10 Buddha's beads herb, 5 to 10 percent of cherokee rose fruit, 5 to 10 percent heartleaf houttuynia herb, 5 to 10 percent of plantain seed, 5 to10 percent of corn stigma, 5 to 10 percent of passiflora perpera mast, 4 to 8 percent of Sspreading hedyotis herb and 5 to 12 percent of climbing nightshade. The Chinese crude drugs by weight percent are weighed and decocted in water and the drug is obtained. The drug can cure toxuria and restore the renal functions of a patient effectively and rapidly.

Description

The uremic medicine of a kind of treatment

Technical field

The invention belongs to the treatment renal failure, uremic Chinese herbal medicine for oral administration specifically is the uremic medicine of a kind of treatment.

Background technology

The main excretion metabolism dead end product of renal function, environment, fluid and electrolyte balance and acid-base balance in regulating.Kidney can produce multiple bioactive substance, as feritin, and erythrogenin etc.Also play an important role on the balance of kidney water in keeping body, it is the constant in to guarantee the indispensable organ of normal activities of environment in keeping.Uremia claims renal insufficiency again, is that heart kidney is all empty, the pathogenesis that accumulates in scorchingly hot.Develop into the serious stage by acute and chronic renal failure, clinical manifestation is metabolism disorder, and water, salt, acid base imbalance store in blood and tissue nitrogen matter and other metabolites, cause the syndrome that body is poisoned.According to statistics, China die from every year the person of uremia account for ten thousand of population/.

For the treatment of this disease, mainly be the inflammation of kidney at present, eliminate the hydrops of kidney; Two kinds of methods are generally arranged: a kind of is to utilize hemodialysis to treat uremia, though effect is obvious, costs an arm and a leg, and non-general entity and individual can bear; Another kind method be with in, the method for the long-pending urinary catheter of Western medicine nephrectasia, though treat at present uremic in, Western medicine is many, the patient who is in a bad way can not use the long-pending urinary catheter of nephrectasia to urinate soon, particularly the women urinates soon and might cause the heart death of overrunning.The toxic and side effects of Western medicine is more intense in addition, and the price comparison height, and therefore long-time use may cause patient's a series of bad side reaction, and increases the weight of patient economy burden.

Summary of the invention

The object of the present invention is to provide the uremic medicine of a kind of treatment, belong to the extract of Chinese herbal medicine combination, it can fundamentally cure uremia, and patient's renal function is recovered fast and effectively.

Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to kidney mechanism, achieve with reference to modern pharmacological research, from motherland's medicine treasure-house, filter out and regulate interior environment, improve the pure natural plant Chinese herbal medicine of renal function,, skim the cream off milk by the theory of Chinese medical science prescription, make it recover the normal of renal function, reach the effect of radical cure.

Technical scheme of the present invention is that the uremic medicine of a kind of treatment is characterized in that the percentage by weight of its herbal raw material is:

Cornu saigae tatariace powder 5～12%, Cornu rhinocerotis 4～8%, the Radix Polygoni Multiflori 4～8%, Semen Persicae 4～8%, Herba Asari 2～5%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 2～5%, hold back 2～5% in vain, Tylophora ouata 5～10%, Fructus Rosae Laevigatae 5～10%, Herba Houttuyniae 5～10%, Semen Plantaginis 5～10%, Stigma Maydis 5～10%, Pe1lionia tsoongii (Merr.) Merr. 5～10%, Herba Hedyotidis Diffusae 4～8%, Herba Solani Lyrati 5～12%;

Preferred version, the percentage by weight of this herbal raw material is:

Cornu saigae tatariace powder 10%, Cornu rhinocerotis 6%, the Radix Polygoni Multiflori 6%, Semen Persicae 6%, Herba Asari 3%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 3% holds back 3% in vain, Tylophora ouata 8%, Fructus Rosae Laevigatae 8%, Herba Houttuyniae 8%, Semen Plantaginis 9%, Stigma Maydis 8%, Pe1lionia tsoongii (Merr.) Merr. 6%, Herba Hedyotidis Diffusae 6%, Herba Solani Lyrati 10%;

The herbal raw material of getting above proportioning weight is fried in shallow oil water preparation and is promptly got this medicine, and every day 2 times during use, each 50 milliliters, auf nuechternen Magen einnehmen can be cured in 5～9 months.

The herbal composite that the present invention proposes can use the conventional method of this area to fry in shallow oil water preparation, also makes various peroral dosage forms, as oral liquid, pill, tablet, decoction, powder, sugar free granule, capsule etc., preferably fries in shallow oil water preparation.

It should be noted that use of the present invention when frying in shallow oil water preparation, if the patient has and spits blood and during gingival hemorrhage, the medicine of should stopping using is considered other cause of disease of inspection; Period in a medicine is eaten iodine salt, prohibits and eats Carnis Canitis, Carnis caprae seu ovis, beef, duck meat, Carnis Gallus domesticus, egg, spring bamboo, Fish.

The medicinal raw material that the present invention is used: cornu saigae tatariace powder, Cornu rhinocerotis, the Radix Polygoni Multiflori, Semen Persicae, Herba Asari, the Pseudobulbus Bletillae (Rhizoma Bletillae) is held back in vain, Fructus Rosae Laevigatae, Herba Houttuyniae, Semen Plantaginis all can be bought from pharmacy, and specification meets national medical standard.Stigma Maydis can obtain from reaping corn processed process, Pe1lionia tsoongii (Merr.) Merr., and Tylophora ouata, Herba Hedyotidis Diffusae, Herba Solani Lyrati all can be gathered in the field from hillside, general rural area, roadside, small stream side.

Compound basis of the present invention is:

Cornu saigae tatariace powder, heat clearing away, the painful abdominal mass of detoxifying, disappear, spasmolytic calmness.

Cornu rhinocerotis, be purify the blood simply branch heat, separate the medicine of pyretic toxicity.Be equipped with Cornu Saigae Tataricae, arresting convulsion then clears away heart-fire.

The Radix Polygoni Multiflori, liver and kidney tonifying, benefiting essence-blood, strengthening bone and muscle can promote erythrocytic generation.

Semen Persicae, bitter in the mouth, sweet, flat, GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling is arranged, the effect of loosening bowel to relieve constipation.

Herba Asari, property suffering, temperature, slightly poisonous are returned lung, kidney, heart channel.The cold expelling of inducing sweat is arranged, wind-expelling pain-stopping, sensible, the warming the lung to resolve fluid-retention effect.

The Pseudobulbus Bletillae (Rhizoma Bletillae), bitter in the mouth, sweet, puckery, cold in nature is returned lung, stomach, Liver Channel.Astringing to arrest bleeding is arranged, the merit of detumescence and promoting granulation, all cards of external haemorrhage in being used for.

Hold back in vain, bitter in the mouth is flat.Main carbuncle cellulitis wound, eliminating stagnation gas, pain relieving heat extraction.

Tylophora ouata has another name called wild Semen Coicis, and perennial herb is high 1～1.5 meter.Stem is upright, and multi-branched, base portion joint are gone up and given birth to adventitious root.Leaf is flat, and is long and wealthy, linear to long lanceolar.Summer autumn leaves axil is bloomed, and is raceme, the circular fruit of knot sclerotin, and light is like pearl.Be born in river bank, limit, mountain stream or the dark and damp mountain valley.The property sweet flat.The energy consumer edema, diuresis, invigorating spleen and reinforcing stomach.

Fructus Rosae Laevigatae, sour, sweet, puckery, flat.Return kidney, bladder, large intestine channel.The controlling nocturnal emission with astringent drugs reducing urination is arranged, the effect of relieving diarrhea with astringents.

Herba Houttuyniae, suffering is slightly cold.Return lung meridian.Heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.

Semen Plantaginis, sweet, be slightly cold.Return liver, kidney, lung, small intestine meridian.Clearing away heat and promoting diuresis is arranged, and eliminating dampness by diuresis is treating stranguria, the effect that makes eye bright.

Stigma Maydis, sweet, flat.Diuresis expels the heat-evil, suppressing the hyperactive liver, function of gallbladder promoting.

Pe1lionia tsoongii (Merr.) Merr., bitter in the mouth, cold.Go into heart channel, available skin skin infection, the red and swollen heat pain of controlling hyperactivity of heart-fire.

Herba Hedyotidis Diffusae, bitter but sweet flavor, warm in nature, nontoxic.Go into the heart, liver, spleen three warps.Function with heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.

Herba Solani Lyrati, supplement to the Herbal claim air draft, white curtain, and bitter in the mouth is slightly cold.Heat clearing away, dampness removing dispels the wind, detoxifcation.The subcutaneous ulcer of harnessing the Yellow River, edema, gonorrhea.

Advantage of the present invention: this medical instrument is effective in cure good, instant effect, and the patient need not hospitalization, has reduced economic expenditure.Herb resource is abundant, is to treat renal failure, the comparatively ideal new drug of uremia at present both at home and abroad, and effective percentage reaches 97%.

For showing the therapeutic effect of medicament of the present invention to nephropathy such as uremias, the present invention is through observation and treatment to 100 routine patient systems, and except that 6 routine therapeutic effect were not obvious, all the other 94 examples were thoroughly cured 5～9 months treatment times.Total effective rate accounts for 94%, invalidly accounts for 6%.

The specific embodiment

Model case 1: thunder XX, woman, Xiao Jia people from town, Jiahe County, Hunan Province.Begin in March, 1984 to go to a doctor, readme was once urinated blood in the time of 18 years old, and in March, 90, through CT, B ultrasonic, kidney figure checks that two kidneys are impaired, right renal atrophy.Through authority's certain expert's hospital therapy 2 years, the state of an illness does not become.Look into: creatinine 2.26mg%, uremic nitrogen 39.52mg%, nauseating, waistline pain, the slight edema of lower limb, pulse condition stagnates and counts.Diagnosis: the chronic kidney hypofunction I phase,

Treatment: grasping one day consumption of herbal raw material of the present invention is: cornu saigae tatariace powder 10 grams, Cornu rhinocerotis 6 grams, the Radix Polygoni Multiflori 6 grams, Semen Persicae 6 grams, Herba Asari 3 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 3 grams, hold back 3 grams in vain, Tylophora ouata 8 grams, Fructus Rosae Laevigatae 8 grams, Herba Houttuyniae 8 grams, Semen Plantaginis 9 grams, Stigma Maydis 8 grams, Pe1lionia tsoongii (Merr.) Merr. 6 grams, Herba Hedyotidis Diffusae 6 grams, Herba Solani Lyrati 10 grams;

Get the above-mentioned raw materials mixing and water adding and decoct 2 times, add 1000～1500 milliliters water at every turn, fry in shallow oil at every turn. boiled 0.5～1 hour, and merged decocting liquid twice, filtration makes 100 milliliters and fries in shallow oil water preparation, takes night and morning each 50 milliliters; After the patient took medicine 6 months, renal function was normal; Check: creatinine 0.93ng%, uremic nitrogen 19.05mg%, hematochrome 16 grams, transference cure, the farming of can going to the field, also fertility had 3 children afterwards, and was complete healthy.

Model case 2: thunder XX, the woman, 18 years old, Guiyang County great pool village people in Hunan suffered from nephropathy 6 years, and on April 7th, 84 went to a doctor.Feel sick, vomiting, lower limb pain can not be walked, the severe edema, the body sense is tired, and the waistline pain is just rare, and tongue is greasy in vain, and pulse condition is slided and is stagnated.Look into: creatinine 4.8mg%, uremic nitrogen 35mg%, hematochrome 5 gram, B ultrasonic: two kidneys chronic lesion that covers changes.

Treatment: grasping one day consumption of herbal raw material of the present invention is: cornu saigae tatariace powder 5 grams, Cornu rhinocerotis 8 grams, the Radix Polygoni Multiflori 8 grams, Semen Persicae 7 grams, Herba Asari 2 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 2 grams, hold back 5 grams in vain, Tylophora ouata 10 grams, Fructus Rosae Laevigatae 6 grams, Herba Houttuyniae 10 grams, Semen Plantaginis 10 grams, Stigma Maydis 5 grams, Pe1lionia tsoongii (Merr.) Merr. 5 grams, Herba Hedyotidis Diffusae 5 grams, Herba Solani Lyrati 12 grams;

Get the above-mentioned raw materials mixing and water adding and decoct 2 times, add 1200～1700 milliliters water at every turn, fry in shallow oil at every turn. boiled 0.5～1 hour, and merged decocting liquid twice, filtration makes 100 milliliters and fries in shallow oil water preparation, takes night and morning each 50 milliliters; After the patient took medicine 9 months, renal function was normal; Look on July 23rd, 91: creatinine 0.7mg%, uremic nitrogen 22.97mg%, hematochrome 7.5 grams, CO2 combining power, CO2 CP 14.03 equivalent parts per millions, transference cure is walked freely, and treatment obtains produce effects, and also fertility had 2 children afterwards, and was complete healthy.

Model case 3: full XX, woman, 14 years old, student, Guiyang County outskirts of a town, Hunan people from north pass, township.On May 16th, 2002 went to a doctor.Feel sick, breathe hard, dizzy, waistline, skin itching, the slight edema of whole body, weak, appetite is poor, and oneself can not be left the bed, creatinine 10mg%, blood urea nitrogen 78.83mg%, CO2 combining power, CO2 CP 18.8 equivalent parts per millions, blood pressure 145/100, the shortened tongue tongue is dark, pulse condition string and stagnating, diagnosis: chronic kidney hypofunction III phase.

Treatment: grasping one day consumption of herbal raw material of the present invention is: cornu saigae tatariace powder 12 grams, Cornu rhinocerotis 4 grams, the Radix Polygoni Multiflori 4 grams, Semen Persicae 8 grams, Herba Asari 5 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 5 grams, hold back 2 grams in vain, Tylophora ouata 5 grams, Fructus Rosae Laevigatae 10 grams, Herba Houttuyniae 5 grams, Semen Plantaginis 5 grams, Stigma Maydis 10 grams, Pe1lionia tsoongii (Merr.) Merr. 10 grams, Herba Hedyotidis Diffusae 4 grams, Herba Solani Lyrati 11 grams;

Get the above-mentioned raw materials mixing and water adding and decoct 2 times, add 800～1200 milliliters water at every turn, fry in shallow oil at every turn. boiled 0.5～1 hour, and merged decocting liquid twice, filtration makes 100 milliliters and fries in shallow oil water preparation, takes night and morning each 50 milliliters; After the patient took medicine 5 months, renal function improved 2 grades, looks into creatinine 4.09mg% on April 9th, 2004, blood urea nitrogen 81.23mg%, and hematochrome 7.6 grams, CO2 combining power, CO2 CP 18.5 equivalent parts per millions, transference cure is taken care of oneself, and the work that can do housework, and is healthy now.

Model case 4: Xiao XX, the man, 18 years old, the man, the student, Guiyang County great pool village people in Hunan suffered from nephropathy 3 years, and on April 20th, 2003 went to a doctor.The slight edema of lower limb pain, the body sense is tired, and tongue is greasy in vain, and pulse condition is slided and is stagnated.

Treatment: grasping one day consumption of herbal raw material of the present invention is: cornu saigae tatariace powder 8 grams, Cornu rhinocerotis 8 grams, the Radix Polygoni Multiflori 8 grams, Semen Persicae 4 grams, Herba Asari 3 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 2 grams, hold back 5 grams in vain, Tylophora ouata 10 grams, Fructus Rosae Laevigatae 5 grams, Herba Houttuyniae 10 grams, Semen Plantaginis 10 grams, Stigma Maydis 5 grams, Pe1lionia tsoongii (Merr.) Merr. 5 grams, Herba Hedyotidis Diffusae 8 grams, Herba Solani Lyrati 9 grams;

Get the above-mentioned raw materials mixing and water adding and decoct 2 times, add 1000～1400 milliliters water at every turn, fry in shallow oil at every turn. boiled 0.5～1 hour, and merged decocting liquid twice, filtration makes 100 milliliters and fries in shallow oil water preparation, takes night and morning each 50 milliliters; After the patient took medicine 5 months, renal function was normal; Transference cure.

Claims (1)

1. treat uremic medicine for one kind, it is characterized in that the percentage by weight of its herbal raw material is:

Cornu saigae tatariace powder 5～12%, Cornu rhinocerotis 4～8%, the Radix Polygoni Multiflori 4～8%, Semen Persicae 4～8%, Herba Asari 2～5%, the Pseudobulbus Bletillae (Rhizoma Bletillae) 2～5%, hold back 2～5% in vain, Tylophora ouata 5～10%, Fructus Rosae Laevigatae 5～10%, Herba Houttuyniae 5～10%, Semen Plantaginis 5～10%, Stigma Maydis 5～10%, Pe1lionia tsoongii (Merr.) Merr. 5～10%, Herba Hedyotidis Diffusae 4～8%, Herba Solani Lyrati 5～12%;

The herbal raw material of getting above proportioning weight is fried in shallow oil water preparation and is promptly got this medicine.