CN101513504A

CN101513504A - Chinese herbal medicine for remedying thrombocytopenia after radiochemotherapy

Info

Publication number: CN101513504A
Application number: CNA200910020118XA
Authority: CN
Inventors: 李�杰
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-03-24
Filing date: 2009-03-24
Publication date: 2009-08-26

Abstract

The invention discloses a Chinese herbal medicine for remedying thrombocytopenia after radiochemotherapy, in particular used for remedying the thrombocytopenia of the patient with tumour caused by the radiochemotherapy. The Chinese herbal medicine consists of nine natural Chinese herbal medicines including astragalus root, dogwood, cogongrass rhizome, moutan cortex, agrimony, field thistle, Yerbadetajo herb, date and turtle carapace glue. For the invention, the materials are available, price is low, side and toxic effect is little and treatment period is short and the treatment towards the thrombocytopenia of the patient with tumour caused by the radiochemotherapy is realized by supplementing qi, nourishing yin, dispelling heat from blood and stopping bleeding.

Description

A kind of Chinese herbal medicine for the treatment of thrombocytopenia behind the chemicotherapy

One, technical field

The present invention relates to a kind of Chinese herbal medicine, specifically a kind of Chinese herbal medicine that is used for the treatment of thrombocytopenia behind the tumour patient chemicotherapy.

Two, background technology

Chemicotherapy is still the important means of malignant tumor Comprehensive Treatment at present, but the lethal effect of non-selectivity in the chemicotherapy process often causes bone marrow depression, causes thrombocytopenia, thereby causes blood coagulation disorders, and patient even concurrent important organ are hemorrhage and dead when serious.For a long time, the caused thrombocytopenia of treatment chemicotherapy lacks active drug always, normal human granular leukocyte, the M-CSF that uses not only costs an arm and a leg but also plays a role slowly, curative effect is undesirable, the platelet suspension that uses not only price is expensive more, and blood product shortage at present, repeatedly also is easy to generate platelet antibody clinically during infusion, cause platelet destruction, make infusion invalid.

Three, summary of the invention

Purpose of the present invention is exactly to provide a kind of to draw materials conveniently in order to solve deficiency of the prior art, and cheap, toxic and side effects is little, and the treatment phase is short, has the Chinese herbal medicine formula of obvious therapeutic action to causing the thrombocytopenia symptom behind the tumour patient chemicotherapy.

Medicine of the present invention is made with following component: (consumption is a weight ratio)

Radix Astragali 7-9%, Fructus Corni 4-6%, Rhizoma Imperatae 16-18%, Cortex Moutan 7-9%, Herba Agrimoniae 16-18%, Herba Cirsii 16-18%, Herba Ecliptae 2-4%, Fructus Jujubae 16-18%, Colla carapax Trionycis 7-9%.

The optimum weight proportioning of medicine of the present invention is: the Radix Astragali 6%, Fructus Corni 5%, Rhizoma Imperatae 17%, Cortex Moutan 8%, Herba Agrimoniae 17%, Herba Cirsii 17%, Herba Ecliptae 3%, Fructus Jujubae 17%, Colla carapax Trionycis 8%.

Solution of the present invention is that the pharmacological action of every flavor natural Chinese medicinal herb is analyzed as follows according to modern pharmacology research:

The Radix Astragali: the sweet in the mouth tepor, contain chemical constituents such as Radix Astragali glycoside and polysaccharide, have tonifying Qi and lifting yang, benefit and defend effects such as consolidating superficial resistance, holder skin ulcer granulation promoting, inducing diuresis to remove edema, can anticoagulant, reduce blood viscosity and coagulability.

Fructus Corni: sour and astringent tepor, contain vitamin substances, have nourishing liver and replenishing blood, the kidney invigorating arresting seminal emission, arresting sweating such as take off admittedly at effect, are the faint medicine of the moon, few the moon of foot, and to the card of the hepatic and renal YIN deficiency, curative effect is excellent.

Rhizoma Imperatae: sweet in the mouth is cold in nature, has clearing away heat and promoting production of body fluid, effects such as cooling blood for hemostasis, the heat of kind lung heat clearing, stomach, because of it has the diuretic effect, thus can heat conduction descending, sweet in the mouth and mud diaphragm not, cold in nature and do not hinder stomach, diuretic and non-impairment of YIN has YIN fluid being insufficient phenomenon person especially with heat symptom-complex, the most suitable.

Cortex Moutan: cold in nature, the bitter in the mouth suffering.Have clearing away heat and cooling blood, merits such as blood circulation promoting competent silt are used for maculae caused by violent heat pathogen, tell, are defeated in battle, have blood in stool, the hectic fever due to YIN-deficiency consumptive fever, and the amenorrhea dysmenorrhea, carbuncle sore tumefacting virus falls and pounces on the pain of injury.

Herba Agrimoniae: pained cool, for the agent of robustness astringing to arrest bleeding, have astringing to arrest bleeding, tonify deficiency, heart tonifying is etc. effect.Can promote blood coagulation, and have the heartbeat of making powerful and adjust the effect of heart rate.Be used to control haemophilia, spit blood, hematuria is had blood in stool, bleeding not during menses, and impairment caused by overstrain is taken off power, carbuncle, traumatic injury, wound hemorrhage.

Herba Cirsii: sweet and slightly bitter taste, gas is cold, and is nontoxic, has removing heat from blood, blood stasis dispelling, effects such as hemostasis are controlled haematemesis, epistaxis, hematuria, stranguria with blood is had blood in stool, metrorrhagia, acute infectious hepatitis, wound hemorrhage, furuncle, carbuncle poison.

Herba Ecliptae: sweet acid is cold, has the kidney invigorating tonifying YIN, and effects such as cooling blood for hemostasis are used for the treatment of the card that deficiency of YIN heat in blood is lost blood, and go into the kidney YIN nourishing again, and invigorating middle warmer is held concurrently clear, and dry for controlling deficiency of YIN blood, medicine is used in flat invigorating the liver and kidney always.

Fructus Jujubae: sweet in the mouth is warm in nature, has the effect of strengthening the spleen and stomach, supplementing QI for promoting the production of body fluid, harmonizing yingfen and weifen, releasing poison of drug, can treat diseases such as insufficiency of stomach anorexia, insufficiency of the spleen loose stool, deficient qi and blood.But auxiliary treatment leukocyte and thrombocytopenia, experiment confirm, the Crataegolic acid in the Fructus Jujubae has inhibitory action to sarcoma, and its specific activity chemotherapeutics fluorouracil is also high.

Colla carapax Trionycis: the cream that is brewed into Carapax Trionycis is used as medicine, and has current blood network, nourishing YIN and supplementing blood, and effects such as lung moistening removing food stagnancy cure mainly osteopyrexia and fever, chronic consumptive disease hemoptysis, malaria mass in the abdomen, QI and blood anemia, amenorrhea difficult labour.

Since the Radix Astragali, Colla carapax Trionycis, Fructus Corni, Fructus Jujubae supplementing QI and nourishing YIN, Rhizoma Imperatae, Herba Ecliptae, Cortex Moutan, Herba Agrimoniae, Herba Cirsii clearing away heat to stop bleeding.The present invention forms prescription with above-mentioned nine flavor natural Chinese medicinal herb, and by supplementing QI and nourishing YIN, cooling blood for hemostasis realizes causing the treatment of thrombocytopenia symptom behind the tumour patient chemicotherapy.

Four, the specific embodiment

Embodiment 1:

Get the Radix Astragali, Fructus Corni, Rhizoma Imperatae, Cortex Moutan, Herba Agrimoniae, Herba Cirsii, Herba Ecliptae, Fructus Jujubae, Colla carapax Trionycis nine flavor natural Chinese medicinal herb, form a prescription.The gross weight of this prescription is decided to be 300 grams, the weight ratio of each natural Chinese medicinal herb of distinguishing the flavor of is calculated with percent, is respectively Radix Astragali 7-9%, Fructus Corni 4-6%, Rhizoma Imperatae 16-18%, Cortex Moutan 7-9%, Herba Agrimoniae 16-18%, Herba Cirsii 16-18%, Herba Ecliptae 2-4%, Fructus Jujubae 16-18%, Colla carapax Trionycis 7-9%.Remove impurity, clean, after the dried, grind to form fine powder with grinding machine and incapsulate.

Embodiment 2:

Get the Radix Astragali, Fructus Corni, Rhizoma Imperatae, Cortex Moutan, Herba Agrimoniae, Herba Cirsii, Herba Ecliptae, Fructus Jujubae, Colla carapax Trionycis nine flavor natural Chinese medicinal herb, form a prescription.The gross weight of this prescription is decided to be 300 grams, the weight ratio of each natural Chinese medicinal herb of distinguishing the flavor of is calculated with percent, is respectively Radix Astragali 7-9%, Fructus Corni 4-6%, Rhizoma Imperatae 16-18%, Cortex Moutan 7-9%, Herba Agrimoniae 16-18%, Herba Cirsii 16-18%, Herba Ecliptae 2-4%, Fructus Jujubae 16-18%, Colla carapax Trionycis 7-9%.Remove impurity, clean, after the dried, decocting is made water preparation, also can concentrate and make pill.

Embodiment 3:

Get the Radix Astragali, Fructus Corni, Rhizoma Imperatae, Cortex Moutan, Herba Agrimoniae, Herba Cirsii, Herba Ecliptae, Fructus Jujubae, Colla carapax Trionycis nine flavor natural Chinese medicinal herb, form a prescription.The gross weight of this prescription is decided to be 300 grams, the weight of each natural Chinese medicinal herb of distinguishing the flavor of is calculated with best proportioning, is respectively the Radix Astragali 6%, Fructus Corni 5%, Rhizoma Imperatae 17%, Cortex Moutan 8%, Herba Agrimoniae 17%, Herba Cirsii 17%, Herba Ecliptae 3%, Fructus Jujubae 17%, Colla carapax Trionycis 8%.

Claims

1, a kind of Chinese herbal medicine for the treatment of thrombocytopenia behind the chemicotherapy is characterized in that: be made up of the Radix Astragali, Fructus Corni, Rhizoma Imperatae, Cortex Moutan, Herba Agrimoniae, Herba Cirsii, Herba Ecliptae, Fructus Jujubae, Colla carapax Trionycis nine flavor natural Chinese medicinal herb; The weight ratio of each natural Chinese medicinal herb of distinguishing the flavor of is respectively Radix Astragali 7-9%, Fructus Corni 4-6%, Rhizoma Imperatae 16-18%, Cortex Moutan 7-9%, Herba Agrimoniae 16-18%, Herba Cirsii 16-18%, Herba Ecliptae 2-4%, Fructus Jujubae 16-18%, Colla carapax Trionycis 7-9%.

2, the Chinese herbal medicine of thrombocytopenia behind the treatment chemicotherapy according to claim 1, the optimum weight proportioning of the natural Chinese medicinal herb of wherein respectively distinguishing the flavor of is respectively: the Radix Astragali 6%, Fructus Corni 5%, Rhizoma Imperatae 17%, Cortex Moutan 8%, Herba Agrimoniae 17%, Herba Cirsii 17%, Herba Ecliptae 3%, Fructus Jujubae 17%, Colla carapax Trionycis 8%.