CN101496812B - Compositional agent for rapid healing large-sized Acipenser sinensis with serious injury - Google Patents

Compositional agent for rapid healing large-sized Acipenser sinensis with serious injury Download PDF

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Publication number
CN101496812B
CN101496812B CN2008100331723A CN200810033172A CN101496812B CN 101496812 B CN101496812 B CN 101496812B CN 2008100331723 A CN2008100331723 A CN 2008100331723A CN 200810033172 A CN200810033172 A CN 200810033172A CN 101496812 B CN101496812 B CN 101496812B
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China
Prior art keywords
vitamin
coenzyme
per kilogram
penicillin
mandarin sturgeon
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Expired - Fee Related
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CN2008100331723A
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Chinese (zh)
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CN101496812A (en
Inventor
刘鉴毅
庄平
章龙珍
张涛
赵峰
冯广朋
黄晓荣
侯俊利
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East China Sea Fishery Research Institute Chinese Academy of Fishery Sciences
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East China Sea Fishery Research Institute Chinese Academy of Fishery Sciences
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Abstract

The invention relates to a quick healing group agent for large seriously injured Chinese sturgeons, relates to species conservation of the Chinese sturgeons, and needs to provide a medicine support of the quick healing group agent for quickly recovering the physique of the Chinese sturgeons. The quick healing group agent uses penicillin, streptomycin sulfate, trinosin, vitamin C, vitamin B6 and coenzyme A, and is characterized in that the dosage of each kilogram of the Chinese sturgeons comprises that: 7,547 units per kilogram of the penicillin, 4,717 units per kilogram of the streptomycin sulfate, 0.3773 milligram per kilogram of the trinosin, 4.717 milligrams per kilogram of the vitamin C, 0.2358 milligram per kilogram of the vitamin B6 and 0.4717 milligram per kilogram of the coenzyme A. The penicillin, the streptomycin sulfate, the trinosin, the vitamin B6 and the coenzyme A are dissolved into a normal saline solution or distilled water; the vitamin C is absorbed by a syringe needle tube; and the six medicines are uniformly mixed to obtain an injection solution of which the total dose is 10 milliliters.

Description

The agent of the quick rehabilitation group of severely injured large-scale mandarin sturgeon
Technical field:
The present invention relates to mandarin sturgeon species conservation technology.
Background technology
Mandarin sturgeon (Acipenser sinensis Gray) is a kind of typical anadromous migration Fish, mainly is distributed in the East Sea, the Huanghai Sea, the Zhujiang River and the main stream of the Yangtze of China.20 th century later; because factors such as overfishing, hydraulic engineering construction, shipping, water pollution; its wild stocks stock number constantly descends; though be listed in animals under first-class state protection in 1988; but from 1981 to 1999 19 in the period of, young sturgeon recruitment stock and the close sturgeon recruitment stock of mandarin sturgeon have still reduced respectively about 80% and 90%.Nineteen eighty-three mandarin sturgeon artificial propagation achieving success, the beginning artificial releasing also continues so far, the mandarin sturgeon artificial propagation techniques has been obtained many important breakthroughs, but a severe problem that faces at present is wild parent fish negligible amounts, the mandarin sturgeon parent that river, 1983-1984 Yichang section is participated in breeding reaches 2176 tails, and 1996-2001 drops to the 292-473 tail.Add that large-scale in recent years wild mandarin sturgeon injures and deaths incident takes place frequently, and in rising trend, and large-scale mandarin sturgeon 2 dead 2 severe injuries in waters are not appeared in the newspapers both at home and abroad to the quick method of rehabilitation of the large-scale mandarin sturgeon of severe injury near the Shanghai Changjiang River mouths in 2007.After carrying out artificial propagation, close sturgeon mortality rate is higher, how to protect wild close sturgeon better, improves the survival rate of wild close sturgeon after artificial propagation, prolongs the wild close sturgeon time-to-live, is the practical problem of pendulum in face of the scientific research personnel.The report of at present domestic relevant rare aquatic animals rehabilitation technique is less, and the rehabilitation research of relevant mandarin sturgeon is almost blank.Mandarin sturgeon quantity is fished in country's strict restriction scientific research, drops to present a few tail by former annual tens tails, and the quantity of large-scale wild ripe mandarin sturgeon is more rare, shows the preciousness of the large-scale wild mandarin sturgeon of every tail especially.
Summary of the invention
The object of the present invention is to provide the agent of the quick rehabilitation group of the large-scale mandarin sturgeon of a kind of severe injury, make severely injured mandarin sturgeon that the medicine support of fast quick-recovery body constitution be arranged, can be from the recovering state of being at death's door to normally moving about.
Technical scheme of the present invention comprises penicillin, streptomycin sulfate, adenosine triphosphate disodium salt, vitamin C, the vitamin B that adopts human 6, coenzyme A, it is characterized in that using dosage calculates by the mandarin sturgeon body weight, the per kilogram of body weight using dosage of mandarin sturgeon is: penicillin 0.7547 ten thousand units/kg, streptomycin sulfate 0.4717 ten thousand units/kg, adenosine triphosphate disodium salt 0.3773mg/kg, vitamin C 4.717mg/kg, vitamin B 60.2358mg/kg, coenzyme A 0.4717mg/kg, with normal saline or distilled water with penicillin, streptomycin sulfate, adenosine triphosphate disodium salt, vitamin B 6, coenzyme A dissolving, and draw vitamin C with the injection needles pipe, above-mentioned 6 kinds of medicines are mixed, being in harmonious proportion evenly, the one-tenth total amount is the 10ml injection.
Beneficial effect of the present invention is to improve the artificial rehabilitation success rate of severely injured large-scale mandarin sturgeon, effectively protects mandarin sturgeon.The synergism of various medicines has strengthened drug effect in the group agent, irritated and uncomfortable stress do not occur, and penicillin has stronger antibacterial action to gram positive bacteria and some gram-negative bacteria, is mainly used in responsive microbial various actute infection; Streptomycin is to tool antibacterial actions such as many gram negative bacillis such as escherichia coli, Klebsiella, Proteus, Enterobacter, Salmonella, Shigella, Brucella, p pestic genus; Adenosine triphosphate disodium salt is a kind of anakinetomer, can directly absorb, and the compound injection with the coenzyme A preparation is used for heart failure, recovers body constitution; Vitamin C promotes the biosynthesis of ossein, is beneficial to the faster healing of tissue injury mouth, strengthens the human body anti-stress ability and the immunity of environment to external world; Vitamin B 6Participate in organism metabolism, contain vitamin B 6Coenzyme main relevant with metabolism, 60 plurality of enzymes need vitamin B 6Coenzyme A is the coenzyme of acetyl reaction in the body, and sugar, fat and proteinic metabolism are played an important role, and synthetic, the hepatic glycogen of acetylcholine accumulates etc. in the body.Of the present invention group of agent and medicine for external use erythromycin are used better effects if.Adenosine triphosphate disodium salt and vitamin can quickly supplement energy; Erythromycin belongs to macrolide antibiotics, smears the wound, to the equal tool antibacterial activity of staphylococcus, each group B streptococcus and Grain-positive bacillus.
The specific embodiment
Claim the mandarin sturgeon body weight earlier, using dosage calculates by the body weight of mandarin sturgeon, the per kilogram of body weight consumption that following every kind of medicine is a mandarin sturgeon: penicillin 0.7547 ten thousand units/kg, streptomycin sulfate 0.4717 ten thousand units/kg, adenosine triphosphate disodium salt 0.3773mg/kg, vitamin C 4.717mg/kg, vitamin B 60.2358mg/kg, coenzyme A 0.4717mg/kg.With normal saline or distilled water with penicillin, streptomycin sulfate, adenosine triphosphate disodium salt, vitamin B 6, coenzyme A dissolving, and draw vitamin C (because vitamin C is the water preparation injection) with the injection needles pipe, above-mentioned 6 kinds of medicines are mixed, being in harmonious proportion evenly, the one-tenth total amount is the 10ml injection.
Mandarin sturgeon good ecological environment is arranged when of the present invention group of agent used, (water quality is pure and fresh, salinity 1-9, oxygen in water 5mg/L, water temperature 10-24 ℃, pH value 6.8-7.2) carries out under the suitable mandarin sturgeon conditions of existence.After will organizing the agent mixed liquor and draw with 10ml injection needles pipe, be expelled in its body from mandarin sturgeon pectoral fin base portion.Of the present invention group of agent and medicine for external use erythromycin are used better effects if.Adenosine triphosphate disodium salt and vitamin can quickly supplement energy; Erythromycin belongs to macrolide antibiotics, smears the wound, to the equal tool antibacterial activity of staphylococcus, each group B streptococcus and Grain-positive bacillus.The mandarin sturgeon wound is dried wound with gauze after cleaning up with normal saline, and erythromycin ointment is smeared on it, if the long 3cm that surpasses of wound surpasses 1cm deeply, must earlier repaste behind the wound suture be smeared erythromycin ointment.Counterweight was hindered mandarin sturgeon and was had an injection coating once every day, and three days is a course of treatment.The present invention (is respectively that 1 cabrage that on January 18th, 2007, yellow sand island mistake was caught is hindered mandarin sturgeon total length 3.35m through Shanghai Changjiang River mouth surrounding waters 2 tails, locate to carry out Rhopilema esculenta operation mistiming and catch huge injured mandarin sturgeon total length 3.37m for 5 nautical miles outside body weight 212kg and on July 17th, the 2007 Jin Hui port, body weight 251kg) the quick rehabilitation of severely injured large-scale wild mandarin sturgeon is implemented to show that survival rate reaches 100%, wherein first cabrage is hindered mandarin sturgeon motionless stupor stage at the bottom of the pond that reposes and can be moved about through rescue in 4 days, return to one's perfect health at last and reach the index of releasing, put back to the Changjiang river smoothly, second tail was through rescue in 2 days, motionless from reposing to normally moving about continuously, rehabilitation, can normally ingest weight increase.

Claims (1)

1. the agent of the quick rehabilitation group of severely injured large-scale mandarin sturgeon comprises the penicillin, streptomycin sulfate, adenosine triphosphate disodium salt, vitamin C, the vitamin B that adopt human 6, coenzyme A, it is characterized in that using dosage calculates by the mandarin sturgeon body weight, the per kilogram of body weight using dosage of mandarin sturgeon is: penicillin 0.7547 ten thousand units/kg, streptomycin sulfate 0.4717 ten thousand units/kg, adenosine triphosphate disodium salt 0.3773mg/kg, vitamin C 4.717mg/kg, vitamin B 60.2358mg/kg, coenzyme A 0.4717mg/kg, with normal saline or distilled water with penicillin, streptomycin sulfate, adenosine triphosphate disodium salt, vitamin B 6, coenzyme A dissolving, and draw vitamin C with the injection needles pipe, above-mentioned 6 kinds of medicines are mixed, being in harmonious proportion evenly, the one-tenth total amount is the 10ml injection.
CN2008100331723A 2008-01-28 2008-01-28 Compositional agent for rapid healing large-sized Acipenser sinensis with serious injury Expired - Fee Related CN101496812B (en)

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RU2665366C2 (en) 2012-05-11 2018-08-29 АрТиАй СЕРДЖИКАЛ, ИНК. Xenograft soft tissue implants and methods of making and using
CN103190364B (en) * 2013-03-29 2015-04-22 中国水产科学研究院长江水产研究所 Method and injection liquid for nursing wild coreius guichenoti

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006126663A1 (en) * 2005-05-27 2006-11-30 Kowa Company, Ltd. Pharmaceutical preparation for recovery from fatigue
CN1887295A (en) * 2006-07-27 2007-01-03 岳天文 Medicine for promoting healing of wound

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006126663A1 (en) * 2005-05-27 2006-11-30 Kowa Company, Ltd. Pharmaceutical preparation for recovery from fatigue
CN1887295A (en) * 2006-07-27 2007-01-03 岳天文 Medicine for promoting healing of wound

Non-Patent Citations (2)

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Title
徐水文等.三磷酸腺苷(ATP)和辅酶A(HSCOA)在兽医临床上的应用.《河南职业技术师范学院学报》.1981,(第1期),p.58第1、3段. *
颜邦斌等.家畜创伤后如何选药和用(换)药.《农村百事通》.2000,(第4期),p.31左栏第2段. *

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