CN101479000A - 具有张紧弹簧和张紧元件的注射装置 - Google Patents

具有张紧弹簧和张紧元件的注射装置 Download PDF

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CN101479000A
CN101479000A CNA200780012879XA CN200780012879A CN101479000A CN 101479000 A CN101479000 A CN 101479000A CN A200780012879X A CNA200780012879X A CN A200780012879XA CN 200780012879 A CN200780012879 A CN 200780012879A CN 101479000 A CN101479000 A CN 101479000A
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injection device
ampoule
spring
coupling element
piston rod
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CN101479000B (zh
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U·莫瑟
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Yishou Pharmaceutical Treatment Co ltd
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Disetronic Licensing AG
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Abstract

本发明涉及一种注射装置，它具有：用于要输出的物质的接纳装置，特别是安瓿固定器(2)，该接纳装置能够相对于注射装置或它的一部分运动；张紧元件，特别是弹簧(6)，其能够支撑在注射装置的一部分上；并且具有耦合元件(5)以用于使接纳装置(2)与弹簧(6)相耦合，因此在将接纳装置(2)导入运动到注射装置中的情况下该弹簧(6)能够被张紧，以及还涉及一种准备注射装置的方法，用于从安瓿(3)中输出物质，其中，注射装置的排出弹簧(6)通过将安瓿(3)装入到注射装置中而被张紧。

Description

具有张紧弹簧和张紧元件的注射装置
技术领域
本发明涉及一种用于输出物质的装置，特别是注射装置或笔(Pen)，其具有弹簧以用于例如从两腔-安瓿中按剂量地给出可注射的产品。该注射仪器最好是用于产品的自给药，特别是用作一次性注射器或自动笔。
背景技术
从US 5,104,380公开了一种注射仪器，其中以手工来实现固定在仪器上的注射针的刺入并且随后自动地通过驱动装置从该仪器中排出有效物质。该驱动装置由弹簧构成，其通过用于调节所希望的给药剂量的剂量元件的运动被张紧。该弹簧被锁定在该张紧状态中直到激活。通过激活，它便自动地驱动排出机构，其通过注射针排出该有效物质。
发明内容
本发明的任务是，提出一种注射装置和一种用于准备注射装置的方法，其使得注射装置的操作更简便。
这一任务通过按权利要求1的注射装置和按方法独立权利要求9的方法来解决。优选的实施方式产生于从属权利要求中。
按本发明的注射装置具有用于要输出的物质的接纳装置，其中该要输出的物质要么可以直接置入或储存在该接纳装置中，要么可以被置入容器中，例如简单的或两腔-安瓿中，因此该接纳装置例如被设置为安瓿固定器。该接纳装置相对于注射装置或笔的壳体是可运动的，其中例如该注射装置的构成该接纳装置或安瓿固定器的元件可以推入或旋入到这个注射装置中或其一部分中，例如该注射装置的壳体中。在采用公知的两腔-安瓿的情况下，可以通过推入或拧入过程使在两腔-安瓿中包含的物质相混合并且因此准备好输出给病人。在该注射装置中或上设置了张紧元件，例如弹簧，其在一侧支撑到该注射装置中的或上的元件上或其壳体上的元件上，例如为此设置的环件或盘件上并且该弹簧按照本发明在离开所述支撑侧或表面的方向上借助于张紧或耦合元件(其可与安瓿固定器连接或耦合)通过置入该安瓿或推入或拧入该安瓿固定器可以被张紧。按照本发明通过置入安瓿被张紧的弹簧可以在这个张紧状态中例如通过可被设置为滑移套筒或行程套头的耦合元件固定，直到该耦合元件(其例如通过与安瓿壳体的耦合保持弹簧张力)例如通过操作释放按钮与安瓿壳体脱离耦合并且使该弹簧松弛。该弹簧可以例如直接或通过所述耦合元件作用到活塞杆上并且将这个活塞杆朝远侧方向挤压，从而通过活塞杆的朝远侧方向的运动将一个或多个堵塞推入到该安瓿中，从而在安瓿中包含的和例如在置入该安瓿时混合的物质被从安瓿中挤出并且因此为了注射而排出。
该耦合元件可集成在安瓿固定器中或者与这个安瓿固定器连接或者被配置在这个安瓿固定器上或者通过可松开的连接例如固定元件或卡扣元件进行固定或者在装入该安瓿固定器时才与安瓿固定器相连接。例如，该耦合元件可以具有至少一个并最好具有两个或更多个固定或卡扣元件，其能实现与安瓿固定器和/或活塞杆的耦合或卡扣。为此该固定或卡扣元件可以是沿径向往内和/或往外被预张紧的并且依此例如在圆筒形或套筒形的耦合元件的情况下可以向内地例如朝活塞杆的方向挤压和/或向外地例如朝注射装置的壳体的方向挤压。
该耦合元件的一个或多个固定或卡扣元件可以具有被斜切的、亦即例如不垂直于注射装置纵轴线的或锥形收敛的表面或分段。例如在注射装置的轴向上挤压到该耦合元件上的构件例如与释放按钮或调节环连接的元件可将使耦合元件保持在轴向固定的位置中的固定或卡扣元件从例如与注射装置的壳体的耦合连接或卡扣连接中松开，从而释放该耦合元件。该耦合元件例如通过由推入安瓿而被预张紧的弹簧的压力朝注射装置的远侧方向运动。在此，该耦合元件的这种进给运动就可以例如借助于耦合或卡扣连接被传递到活塞杆上。
最好是该耦合元件不可转动地支承在活塞杆上。例如该活塞杆可以具有非圆的型廓并且例如可以是矩形或方形横截面，其中该耦合元件例如可构造成套筒形的并且可以具有导引区域，活塞杆在该导引区域中可以沿轴向移动地导引，因此该耦合元件可在轴向上沿着活塞杆运动。同样地可以在活塞杆中或上沿纵向设置沟槽或隔片，同时在耦合元件上可以设置相应的配对元件，亦即例如隔片或沟槽。
最好是该安瓿固定器借助螺纹与注射装置或与其壳体相连接，从而该安瓿固定器可以被拧入到注射装置中。作为优选，该安瓿固定器具有外螺纹，其可被拧入到注射装置的内螺纹中。同样地，也可以将安瓿固定器简单地推入到注射装置中而没有相对转动。
为了调节要输出的剂量而在注射装置上设置的剂量调节环最好是被锁定的，也就是说相对于注射装置是不可转动的或者只可非常有限地转动，直到该安瓿被完全装入。为此在剂量调节环上设置一个或多个止挡，其在装入安瓿固定器的状态中是可无阻碍地运动的。作为优选，该止挡可至少部分地运行在沟槽中、特别是环槽中。该沟槽可被设置在于壳体内部布置的功能套筒上。在没有装入安瓿固定器的状态中，所述止挡与一个或多个配对止挡相对置，因此它们的运动被锁定。配对止挡可以通过装入安瓿固定器而被置于该剂量调节环的止挡的运动轨道外部，因此该剂量调节环可以为了剂量调节而自由转动。为此例如该功能套筒可以作为整体相对于剂量调节环地移动或者可以对该功能套筒进行划分，使得只有该功能套筒的一部分在装入该安瓿固定器时进行移动，例如使得配对止挡从环槽中运动出来。
最好是将用于排出过程的释放按钮与剂量调节环耦合，以便在借助调节环调节剂量时该释放按钮从注射装置的壳体中移出。为此可以例如在释放按钮和调节环之间设置螺纹形式的耦合，因此例如不可转动地支承的释放按钮通过调节环的转动从注射装置中旋出。
在一种实施方式中，该释放按钮例如不可转动地但在轴向上可运动地布置在剂量调节环上。通过剂量调节环的旋转运动，该释放按钮可以沿着导向滑槽在轴向上相对于剂量调节环运动。作为导向滑槽例如适用倾斜表面，其被相互协调地布置在释放按钮上和相对剂量调节环不可转动的元件例如功能套筒上。最好是该释放按钮如此程度埋陷地布置在壳体中或者说剂量调节环中，使得它是不可接近的，只要它未通过装入该安瓿固定器或者说未通过剂量调节环的转动被激活。
在调节过程结束以后，该释放按钮处于可激活的位置中。通过操作该按钮，就可以释放排出过程。在此作为优选，该释放按钮可又被带到埋陷的位置中，在该位置中它对于另外的操作是不可接近的。在一种特别优选的实施方式中，该剂量调节环在排出有效物质以后也就是说在操作该释放按钮之后又处在被锁定的位置中。因此该注射装置在一次唯一的排出之后对于另外的操作来说是被完全锁住的。它既不能实现另外的剂量调节也不能重新操作该释放按钮。该笔则完全地被锁定了。
此外本发明涉及一种用于准备注射装置的方法，用于从安瓿中输出物质，其中在注射装置中包含的弹簧通过将安瓿或安瓿固定器推入到注射装置中或其壳体中被张紧。作为优选，注射可以如此实现，即，该被张紧的弹簧例如在操作释放按钮之后又松弛并且将一个力施加到活塞杆上，该活塞杆被推入到该安瓿中。
附图说明
下面借助实施例描述本发明。附图表明：
图1A和1B是在旋入安瓿以前具有松弛的排出弹簧的注射装置的相互垂直的纵剖图，
图1C和1D是图1A和1B的注射装置的相互垂直的侧视图，
图2A和2B是在旋入安瓿后具有张紧的排出弹簧的注射装置的相互垂直的纵剖图，
图2C和2D是图2A和2B的注射装置的相互垂直的侧视图，
图3A和3B是在借助调节环进行计量以后具有伸出的释放按钮的注射装置的纵剖图，和
图3C和3D是图3A和3B的注射装置的相互垂直的侧视图，
图4A和4B是注射装置在压入释放按钮并为排出剂量释放弹簧之后在终端位置中的纵剖图，
图4C和4D是图4A和4B的注射装置的相互垂直的侧视图。
具体实施方式
图1A表明了按本发明的在图1C中示出的注射装置的实施方式的纵向横截面图，其中内部插入安瓿3的安瓿固定器2借助该安瓿固定器2的外螺纹2a被部分地拧入到该注射装置或者说笔的壳体4内的内螺纹4a中。该安瓿3是两腔-安瓿并且具有两个堵塞3a和3b，其将两种要混合的并在原始位置中相互分开的物质封闭在该安瓿3中。活塞杆1通过从该活塞杆1沿径向突出的环件1b在轴向上固定以防止朝近侧方向移动，该环件1b靠置在由隔片4b构成的通孔上，该通孔要小于环件1b的外径。在活塞杆1上不可转动地并能在该活塞杆1上移动地设置了滑移套筒或行程套头5作为耦合元件。
图1B表明了图1A中示出的笔在图1D示出的剖切平面中的横截面视图，该剖切平面垂直于图1A示出的剖切平面。该滑移套筒5具有沿径向往内被预张紧的卡扣元件5a，其卡入到活塞杆1的凹槽1c中并因此在该基本位置中是松弛的。弹簧6支承到该注射装置内部的靠置表面4b上并且在图1中示出的基本位置中是松弛的。
在将该安瓿固定器2拧入到壳体4中的情况下，该安瓿3的后边的堵塞3b靠置在活塞杆1的靠置元件1e上并且在将安瓿固定器2进一步旋入的情况下，该安瓿3的后边堵塞3b则相对于该安瓿3被推入到这个安瓿3中，这样就导致在两腔-安瓿3中包含的物质的混合。
图2A示出了由图1A示出的注射装置在将安瓿固定器2旋入到壳体4中后的情况。该滑移套筒5是借助径向上往外被预张紧的固定元件5b与安瓿固定器2耦合的，并且通过安瓿固定器2朝注射装置的近侧方向的旋入移动。因此它导致弹簧6在靠置表面4b和5c之间张紧，其最好是在整个安瓿推入运动期间并至少在安瓿推入运动的一部分期间与该滑移套筒5的近侧的表面5c相靠置，而且通过滑移套筒5被压缩并因此被预张紧。该滑移套筒5的径向上往里被预张紧的卡扣元件5a被从活塞杆1的凹槽1c中拉出并且在图2B所示出的位置中卡扣到活塞杆1的后边的凹槽1d中。
剂量调节环在拧入安瓿固定器2之前相对于壳体4不可转动。为此该剂量调节环具有止挡，其被设置在沿圆周方向布置的柔性臂上。该止挡与设置在功能套筒上的环槽对置。在计量运动时，该止挡通过柔性臂的运动被压入到该环槽中，因为与所述臂相对置地设置了齿部，所述臂可沿着齿部运动，同时产生可听见的卡嗒响声。如果该柔性臂通过这些齿运行，则它们在每个齿处被压入到环槽中。该功能套筒相对于壳体是不可转动的并被构造成两部件的，其中这两个部件相对彼此可伸缩式移动。在功能套筒的部件在轴向上彼此拉出的状态中，配对止挡则到达环槽的内部，该配对止挡与所述剂量调节环上的止挡相对置并且锁定该剂量调节环的转动。在功能套筒的部件轴向上相对推合的状态中，该配对止挡则到达该环槽的轨道的外部，因此该剂量调节环可以转动。该功能套筒的部件的相对移动通过安瓿固定器2的旋入来实现。因此该剂量调节环只有当安瓿固定器2被装入时才可以转动。
图3A示出了由图2A所示的注射装置，在调节环9为了调节剂量被转动之后，其中释放按钮7通过调节环9的调节运动借助滑槽导向装置从注射装置中移出。为此在该功能套筒的近侧的端面上设置了往近侧伸出的具有倾斜表面的突起。在该释放按钮的远侧的端面上设置了往远侧伸出的具有倾斜表面的突起，其与功能套筒的所述表面是互补的。在该剂量调节环转动时，该释放按钮被携带运动并且相对于功能套筒转动，同时倾斜表面在彼此上面滑动并且因此该释放按钮相对于功能套筒和剂量调节环在轴向上移动。由此该释放按钮被从陷入状态置于可操作的状态。
在将释放按钮压入到注射装置中时，功能套筒作用到滑移元件5上并且将所述弹簧释放。在这种情况下，功能套筒构成释放元件8。
在释放按钮7的内侧面上，如在图3B中所示，设置了不同轴向长度11和12的沟槽，例如通过沟槽7a和7b所示的那样，其确定了活塞杆1的最大可能的轴向运动，该活塞杆1在它的近侧的端部上具有凸耳1a，其在将由弹簧6预张紧的活塞杆1释放以后到达限界相应的沟槽7a，7b的止挡7c或7d并且因此确定最大可能的排出剂量。
如果该释放按钮7被压入到注射装置中，如在图4A中所示，则该径向上往外被预张紧的固定元件5b(其将滑移套筒5保持在安瓿固定器2的近侧的端部上)借助于与按钮7配合作用的释放元件8(其压到该固定元件5b的倾斜表面5c上并因此使这个固定元件沿径向往里移动)与安瓿固定器2脱离啮合，因此该滑移套筒5在轴向上不再被相对于注射装置锁定。压在滑移套筒5上的弹簧6就将滑移套筒5往远侧方向移动。因为滑移套筒5借助于径向上往里被预张紧的卡扣元件5a(其卡扣到活塞杆1的凹槽1d中)带动活塞杆1，故活塞杆1被推入到安瓿3中并因此挤压到后边的堵塞3b上，这样就导致将安瓿3中所含的被混合的物质排出。
在图4B中示出的从安瓿3中排出所述剂量之后的位置中，该释放按钮7由活塞杆1的凸耳1a保持在注射装置中并且不能再被拉出，因此该注射装置也就不再能够被用于另外的注射了。

Claims (9)

1.注射装置，具有：用于要输出的物质的接纳装置，特别是安瓿固定器(2)，该接纳装置能够相对于注射装置或它的一部分运动；排出弹簧(6)，其能支撑在注射装置的一部分上；并且具有耦合元件(5)以用于使接纳装置与排出弹簧(6)相耦合，因此在将接纳装置(2)导入运动到注射装置中的情况下该弹簧(6)能够张紧，其中该弹簧被构造成作用在注射装置的活塞杆(1)上以用于排出物质。
2.按权利要求1的注射装置，其特征在于：
所述耦合元件(5)是套筒形的元件。
3.按前面权利要求之一的注射装置，其特征在于：
所述耦合元件(5)具有至少一个固定或卡扣元件(5a，5b)，以便使耦合元件(5)与接纳装置(2)和/或与注射装置的活塞杆(1)能松开地或不能松开地连接。
4.按前面权利要求之一的注射装置，其特征在于：
所述耦合元件(5)具有锥形构成的或设有倾斜延伸的表面的接触元件(5c)。
5.按前面权利要求之一的注射装置，其特征在于：
所述耦合元件(5)不能转动地支承在活塞杆(1)上。
6.按前面权利要求之一的注射装置，其特征在于：
所述接纳装置(2)借助于螺纹(2a，4a)与注射装置相耦合。
7.按前面权利要求之一的注射装置，其特征在于：
剂量调节环(9)能被锁定，直到安瓿(3)完全被装入。
8.按前面权利要求之一的注射装置，其特征在于：
所述注射装置的释放按钮(7)通过调节环(9)的转动能够被移出。
9.用于准备注射装置的方法，用于从安瓿(3)中输出物质，其中，所述注射装置的排出弹簧(6)通过将安瓿(3)置入到注射装置中被张紧。
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US8343103B2 (en) 2013-01-01
WO2007115424A1 (de) 2007-10-18
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DK2010252T3 (da) 2011-04-11
DE502007006029D1 (de) 2011-02-03
US20090259181A1 (en) 2009-10-15
JP2009533094A (ja) 2009-09-17
DK2010252T4 (da) 2021-11-08
EP2010252A1 (de) 2009-01-07
CN101479000B (zh) 2012-08-15
AU2007236526A1 (en) 2007-10-18
JP5066177B2 (ja) 2012-11-07

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