CN101455830A - Traditional Chinese medicine composition for treating alopecia and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating alopecia and preparation method thereof Download PDFInfo
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- CN101455830A CN101455830A CNA2008102032923A CN200810203292A CN101455830A CN 101455830 A CN101455830 A CN 101455830A CN A2008102032923 A CNA2008102032923 A CN A2008102032923A CN 200810203292 A CN200810203292 A CN 200810203292A CN 101455830 A CN101455830 A CN 101455830A
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Abstract
The invention relates to a traditional Chinese medicine composition with the efficacies of tonifying liver and kidney capable of promoting blood circulation by removing blood stasis, diverging wind-evil and curing phalacrosis, and a method for preparing the same. The composition is prepared from the following raw materials by weight portion: 2 to 6 portions of glossy privet fruit, 2 to 6 portions of ginkgo leaf, 1 to 4 portions of lopseed, 1 to 4 portions of hawthorn, 1 to 4 portions of grifola, 1 to 4 portions of radix-polygoni multiflori, and 1 to 3 portions of ginger. The preparation method comprises the following steps: crushing the drugs; mixing the crushed drugs; adding ethanol to the mixture to perform percolation; collecting percolate to be filtered; filtering the percolate; and preparing the filtrate after treatment into pharmaceutically acceptable external preparations by the prior technique. The composition has exact efficacy without toxic side effects; besides, the composition is prepared into modern preparations by adopting the preparation method of the invention for convenience use.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, especially a kind of Chinese medicine composition for the treatment of alopecia and preparation method thereof.
Background technology
Alopecia is the more common a kind of disease of department of dermatologry, clinical findings, because the quickening of rhythm of life, operating pressure strengthens, and increasing the weight of of environmental pollution in addition influenced the function of immune system of human body, and the patient who suffers from alopecia increases to some extent.According to clinical findings and relevant bibliographical information, primary disease has increasing trend, domestic 1766 male of Han nationality survey results is shown that the male pattern alopecia patients reach 533 people, and prevalence reaches 30.2%, and some national prevalences are then higher, reach 71% as Japan.In addition, and under tumor, cancer trend occurred frequently day by day, utilize put, the chemotherapeutic treatment means are also quite general, but put, caused alopecia does not have effective medicine to treat after the chemotherapy.Primary disease influences patient's appearance, along with the raising of living standards of the people, the treatment of primary disease is come into one's own day by day.
The definite pathogenic factor of alopecia and pathogenesis still do not have final conclusion so far, should be result of various factor comprehensive action.The traditional Chinese medical science thinks that the etiology and pathogenesis of alopecia is that vim and vigour void declines, and deficiency of kidney-QI is subjected to due to the ailment said due to cold or exposure again.
Western medical treatment alopecia, effect are still undesirable, though certain hair regrowth is arranged, side effect is big, the relapse rate height; The traditional Chinese medical science accumulated certain effective side's medicine and method, but these side's medicines usually exists prescription huge in the practice of treatment alopecia, use inconvenience, shortcomings such as patient's poor compliance.
Summary of the invention
Problem to be solved by this invention provides a kind of external medicine composition for the treatment of alopecia, makes its liver and kidney tonifying, blood circulation promoting and blood stasis dispelling, disperses ailment said due to cold or exposure; Safe and effective, patient's compliance height.
Another technical problem to be solved by this invention provides a kind of preparation method of Chinese medicine composition, is made into modern preparation, the convenient use.
In order to solve the problems of the technologies described above, the present invention proposes following technical proposals:
A kind of Chinese medicine composition for the treatment of alopecia is characterized in that described compositions made by the raw material of following weight portion: Fructus Ligustri Lucidi 2-6 part, Folium Ginkgo 2-6 part, Herba speranskiae tuberculatae 1-4 part, Fructus Crataegi 1-4 part, Polyporus 1-4 part, Radix Polygoni Multiflori 1-4 part, Rhizoma Zingiberis Recens 1-3 part.
The proportioning raw materials of the present composition is preferred: 4 parts of Fructus Ligustri Lucidi, 4 parts of Folium Ginkgos, 3 parts of Herba speranskiae tuberculataes, 3 parts of Fructus Crataegis, 3 parts of Polyporus, 3 parts of Radix Polygoni Multiflori, 2 parts in Rhizoma Zingiberis Recens.
All medicines share in the side, play liver and kidney tonifying, blood circulation promoting and blood stasis dispelling altogether, disperse the merit of ailment said due to cold or exposure, can be used for alopecia.The useful technique effect that the present invention treats alopecia can embody by following clinical trial:
Test routine clinical trial
1, clinical data
This is organized among the 200 routine patients, male 172 examples, women 28 examples; Age 25-60 year, wherein 30-45 year 184 examples.Course of disease 1-30 does not wait, and average 8 years, 5-15 171 examples.Obvious bald person 165 examples, brain worker's 169 examples account for 84.5%.
Diagnostic criteria: 1. hair is sparse even bald; Though 2. the hair nothing is obviously sparse, come off obviously the more preceding obvious minimizing of conscious hair in the recent period; 3. there be not the other diseases relevant in the recent period with alopecia; 4. the dandruff increases; 5. hair is shinny, and the scalp oils and fats is obvious; 6. scalp itch.Allly meet preceding 2, possess the 3rd, add that 2 above persons can be diagnosed as seborrheic alopecia in back 3.
2, Therapeutic Method
Present composition using method: be applied to the part outward 2 times every day, and rubbed scalp 2 minutes, 3 months was 1 course of treatment.
3, therapeutic outcome
Curative effect determinate standard: produce effects: have slightly black hard the sending out of a large amount of new lives to grow, I and he feels remarkable improvement per capita, and other symptoms are significantly improved.Effectively: slightly black hard the sending out and part fine hair on birds or animals hair of a small amount of new life arranged, be difficult for discovering, other symptoms make moderate progress.Little effect: do not grow hard sending out, have only the fine hair on birds or animals hair, other symptoms are slightly improved (comprise alopecia and reduce more than 50 days, pruritus alleviates, and dandruff reduces, oils and fats minimizing etc.).Invalid: without any reaction.
The result: after finishing for 1 course of treatment, produce effects 175 examples (87.5%), effective 11 examples (5.5%), little effect 8 examples (4.0%), wherein have 2 examples not adhere to treatment at invalid 4 examples (2.0%).
4, model case
Liu, the man 35 years old, goes to a doctor in April, 2005.The patient told before 5 years and begins alopecia, and obviously increase the weight of nearly half a year.Scalp itch, dandruff increases, and oils and fats is many.Through looking into: hair is sparse to bald, top scalp light, rarely seen tens hairs, and a little fine hair on birds or animals hair.Patient's body is more fat.Have rosy cheeks, spirit still can, amount of sleep is few.Red tip of the tongue, yellow fur, deep and stringy pulse.Treatment as stated above advises it to increase sleep, eats the vegetable egg white matter more, few edible oil fat.The back further consultation of 2 weeks, patient's alopecia obviously reduces, and does not itch substantially, and is fuel-displaced few.After 2 months, have slightly black hard the sending out of a large amount of new lives to grow, more kith and kin have and mention.After 3 months, the top hair is more preceding obviously dense.
The present composition can prepare by following method: with pulverizing medicinal materials, mix, adding percent by volume is the ethanol percolation of 30-90%, collect the percolate that medical material gross weight 3-8 doubly measures, filter, filtrate after treatment, technology is made pharmaceutically acceptable external preparation routinely.
Percolation is preferred 70% with concentration of alcohol, and the amount of collecting percolate is preferably 5 times of amounts of medical material gross weight.
The dosage form of the present composition is selected from a kind of in gel, ointment, tincture, the spray.
External when Chinese medicine composition of the present invention is used for the treatment of alopecia, different according to the state of an illness and occupation mode, daily crude drug amount is 1-100g.
Technical scheme of the present invention hereinafter will do further statement, but the scope of protection of present invention is not limited to following embodiment in order better to illustrate to its specific embodiment.
The specific embodiment
Embodiment 1
Prescription: Fructus Ligustri Lucidi 244g, Folium Ginkgo 244g, Herba speranskiae tuberculatae 122g, Fructus Crataegi 122g, Polyporus 122g, Radix Polygoni Multiflori 122g, Rhizoma Zingiberis Recens 122g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 30% ethanol percolation, collects the percolate of 3 times of amounts of medical material gross weight, filters, and the filtrate fill promptly gets tincture 3000ml.
Embodiment 2
Prescription: Fructus Ligustri Lucidi 244g, Folium Ginkgo 244g, Herba speranskiae tuberculatae 122g, Fructus Crataegi 122g, Polyporus 122g, Radix Polygoni Multiflori 122g, Rhizoma Zingiberis Recens 122g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 90% ethanol percolation, collects the percolate of 8 times of amounts of medical material gross weight, filters, and decompression filtrate recycling ethanol is to 5000ml, and fill promptly.
Embodiment 3
Prescription: Fructus Ligustri Lucidi 244g, Folium Ginkgo 244g, Herba speranskiae tuberculatae 122g, Fructus Crataegi 122g, Polyporus 122g, Radix Polygoni Multiflori 122g, Rhizoma Zingiberis Recens 122g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filters, and the filtrate fill promptly gets tincture 5000ml.
Embodiment 4
Prescription: Fructus Ligustri Lucidi 213g, Folium Ginkgo 213g, Herba speranskiae tuberculatae 142g, Fructus Crataegi 142g, Polyporus 142g, Radix Polygoni Multiflori 142g, Rhizoma Zingiberis Recens 106g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filters, and the filtrate fill promptly gets tincture 5000ml.
Embodiment 5
Prescription: Fructus Ligustri Lucidi 81g, Folium Ginkgo 244g, Herba speranskiae tuberculatae 163g, Fructus Crataegi 163g, Polyporus 163g, Radix Polygoni Multiflori 163g, Rhizoma Zingiberis Recens 122g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filters, and the filtrate fill promptly gets tincture 5000ml.
Embodiment 6
Prescription: Fructus Ligustri Lucidi 471g, Folium Ginkgo 157g, Herba speranskiae tuberculatae 78g, Fructus Crataegi 78g, Polyporus 157g, Radix Polygoni Multiflori 78g, Rhizoma Zingiberis Recens 78g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filters, and the filtrate fill promptly gets tincture 5000ml.
Embodiment 7
Prescription: Fructus Ligustri Lucidi 96g, Folium Ginkgo 96g, Herba speranskiae tuberculatae 191g, Fructus Crataegi 191g, Polyporus 191g, Radix Polygoni Multiflori 191g, Rhizoma Zingiberis Recens 143g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filters, and the filtrate fill promptly gets tincture 5000ml.
Embodiment 8
Prescription: Fructus Ligustri Lucidi 347g, Folium Ginkgo 347g, Herba speranskiae tuberculatae 58g, Fructus Crataegi 58g, Polyporus 174g, Radix Polygoni Multiflori 58g, Rhizoma Zingiberis Recens 58g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filters, and the filtrate fill promptly gets tincture 5000ml.
Embodiment 9
Prescription: Fructus Ligustri Lucidi 200g, Folium Ginkgo 200g, Herba speranskiae tuberculatae 150g, Fructus Crataegi 150g, Polyporus 150g, Radix Polygoni Multiflori 150g, Rhizoma Zingiberis Recens 100g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filters, and the filtrate fill promptly gets tincture 5000ml.
Embodiment 10
Prescription: Fructus Ligustri Lucidi 200g, Folium Ginkgo 200g, Herba speranskiae tuberculatae 150g, Fructus Crataegi 150g, Polyporus 150g, Radix Polygoni Multiflori 150g, Rhizoma Zingiberis Recens 100g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filter, decompression filtrate recycling ethanol filters to 1000ml, add an amount of soil temperature-80 and Buddhist nun and compel golden ethyl ester, pour into sprayer bottle, promptly.
Embodiment 11
Prescription: Fructus Ligustri Lucidi 200g, Folium Ginkgo 200g, Herba speranskiae tuberculatae 150g, Fructus Crataegi 150g, Polyporus 150g, Radix Polygoni Multiflori 150g, Rhizoma Zingiberis Recens 100g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filter, decompression filtrate recycling ethanol, and concentrate, it is an amount of that above-mentioned concentrated solution is added lanoline, vaseline, stearic acid, and mixing is made ointment 1000g.
Embodiment 12
Prescription: Fructus Ligustri Lucidi 200g, Folium Ginkgo 200g, Herba speranskiae tuberculatae 150g, Fructus Crataegi 150g, Polyporus 150g, Radix Polygoni Multiflori 150g, Rhizoma Zingiberis Recens 100g
Method for making: with pulverizing medicinal materials, mix, the adding percent by volume is 70% ethanol percolation, collects the percolate of 5 times of amounts of medical material gross weight, filters, and decompression filtrate recycling ethanol, and concentrate; It is an amount of to take by weighing carbomer-940, adds the distillation aqueous fusion and expands, and adds above-mentioned concentrated solution and an amount of propylene glycol, and the colloid mill mix homogeneously makes gel 1000g.
Claims (7)
1, a kind of Chinese medicine composition for the treatment of alopecia is characterized in that described compositions made by the raw material of following weight portion: Fructus Ligustri Lucidi 2-6 part, Folium Ginkgo 2-6 part, Herba speranskiae tuberculatae 1-4 part, Fructus Crataegi 1-4 part, Polyporus 1-4 part, Radix Polygoni Multiflori 1-4 part, Rhizoma Zingiberis Recens 1-3 part.
2, Chinese medicine composition according to claim 1 is characterized in that its raw material by following weight portion makes: 4 parts of Fructus Ligustri Lucidi, 4 parts of Folium Ginkgos, 3 parts of Herba speranskiae tuberculataes, 3 parts of Fructus Crataegis, 3 parts of Polyporus, 3 parts of Radix Polygoni Multiflori, 2 parts in Rhizoma Zingiberis Recens.
3, the preparation method of the described Chinese medicine composition of claim 1 is characterized in that described method comprises the following steps:
With pulverizing medicinal materials, mix, add ethanol percolation, collect percolate, filter, after filtrate was handled, technology was made pharmaceutically acceptable external preparation routinely.
4, preparation method according to claim 3 is characterized in that described percolation technological parameter is: adding percent by volume is the ethanol of 30-90%, collects the percolate that medical material gross weight 3-8 doubly measures.
5, preparation method according to claim 4 is characterized in that described alcoholic acid percent by volume is 70%.
6, preparation method according to claim 4, the amount that it is characterized in that described collection percolate are 5 times of amounts of medical material gross weight.
7, according to each described preparation method of claim 3-6, the dosage form that it is characterized in that described external preparation is selected from a kind of in gel, ointment, tincture, the spray.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008102032923A CN101455830A (en) | 2008-11-25 | 2008-11-25 | Traditional Chinese medicine composition for treating alopecia and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2008102032923A CN101455830A (en) | 2008-11-25 | 2008-11-25 | Traditional Chinese medicine composition for treating alopecia and preparation method thereof |
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| CN101455830A true CN101455830A (en) | 2009-06-17 |
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| CNA2008102032923A Pending CN101455830A (en) | 2008-11-25 | 2008-11-25 | Traditional Chinese medicine composition for treating alopecia and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102743641A (en) * | 2012-01-26 | 2012-10-24 | 宁波市江北威曼生物科技有限公司 | External health-care product for promoting growth of hair |
| CN102885941A (en) * | 2012-09-20 | 2013-01-23 | 江苏天宇石化冶金设备有限公司 | Pilatory |
-
2008
- 2008-11-25 CN CNA2008102032923A patent/CN101455830A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102743641A (en) * | 2012-01-26 | 2012-10-24 | 宁波市江北威曼生物科技有限公司 | External health-care product for promoting growth of hair |
| CN102885941A (en) * | 2012-09-20 | 2013-01-23 | 江苏天宇石化冶金设备有限公司 | Pilatory |
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Open date: 20090617 |