CN101444296B - Aided blood pressure-lowering health drink and preparation method and usage thereof - Google Patents

Aided blood pressure-lowering health drink and preparation method and usage thereof Download PDF

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CN101444296B
CN101444296B CN2008101068576A CN200810106857A CN101444296B CN 101444296 B CN101444296 B CN 101444296B CN 2008101068576 A CN2008101068576 A CN 2008101068576A CN 200810106857 A CN200810106857 A CN 200810106857A CN 101444296 B CN101444296 B CN 101444296B
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blood pressure
hawthorn
chrysanthemum
health
lowering
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CN101444296A (en
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范玫玫
简晖
龚建平
王跃生
游剑
何秀菊
钱霞
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Jiangxi Bencao Tiangong Technology Co Ltd
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Abstract

The invention relates to a Chinese medicine, food and health food, in particular to an aided blood pressure-lowering health product comprising corn stigma, kudzu root, chrysanthemum, hawthorn and lophatherum gracile, especially an aided blood pressure-lowering health drink and a preparation method and usage thereof. The health drink is prepared by raw materials with the following weight proportions: 1-30 portions of the corn stigma, 1-30 portions of the kudzu root, 1-15 portions of the chrysanthemum, 1-15 portions of the hawthorn and 1-15 portions of the lophatherum gracile. The health drink can help lower blood pressure, blood lipid and blood glucose. The health drink is safe and nontoxic and is suitable for long-term consumption.

Description

A kind of health drink of aided blood pressure-lowering
Technical field
The present invention relates to Chinese medicine, food and health food, especially contain the health drink of the health products of the aided blood pressure-lowering of corn stigma, the root of kudzu vine, chrysanthemum, hawthorn, lophatherum gracile, particularly aided blood pressure-lowering.
Background technology
Hypertension is modal angiocardiopathy, and its incidence of disease increases with advancing age.According to estimates, have 26% to suffer from hypertension in the global population approximately, then turned over some but the age is the crowd's in 60-69 year the incidence of disease, up to about incidence of disease more than 50%, 70 years old then up to 75%.The hypertensive illness rate of China was 11.6% in 1992, and at present China 35 is to 74 years old crowd, and the hypertensive incidence of disease is up to 27%, and number is near 100,013,000.High blood pressure is prone to cause the complication of internal organs such as the heart, brain, kidney, and human beings'health in serious harm, and case fatality rate and disability rate are all very high.
Advantages such as in the hypertensive process of clinical treatment, Western medicine is because of acting on rapidly, and is rapid-action obtain doctor and patient's favor; But the bad situation of result of treatment often appears; Particularly the senile hypertension patient even select medicine appropriate, also not necessarily obtains satisfactory effect; Its reason is that the elderly merges metabolic disorder more, like hyperlipidemia, diabetes.
These the three types of diseases of hypertension, high fat of blood and hyperglycaemia that are commonly called as " three height " are the diseases that have a strong impact on human work, studying and living at present.Hypertension, high fat of blood and hyperglycaemia are closely related again: high fat of blood can increase the weight of diabetes; So the diabetic is usually except treatment control blood sugar height; Also need regulate blood fat, controlling blood sugar and blood fat simultaneously is the key that reduces diabetic's death rate and disability rate.High fat of blood then can directly cause hypertension, rises because of the blood fat height makes blood viscosity, in arterial wall, forms the atheromatous plaque that disperses, hemadostewnosis, and resistance strengthens, and blood pressure is increased.Antihypertensive drugs is also influential to blood lipid metabolism, influences blood lipid metabolism like beta-blocker and diuretics, can cause high fat of blood again.Therefore the control of hypertension, high fat of blood, hyperglycaemia needs to solve simultaneously.So it is not good enough that single step-down treatment is often produced effects, and should effectively control blood fat and blood sugar, promptly adds with lipid lowerers (like statins) and antidiabetic drug.But three types of same usefulness of medicine have not only increased patient's medical expense, and possibly increase the weight of the patient's body burden because the interaction between medicine causes bad reaction.
Though Chinese medicine is fast not as the Western medicine curative effect in step-down, side effect is little, is fit to long-term use the, the particularly Chinese medicine of some medicine-food two-purposes; Be used for dietotherapy for a long time in China, security is extensively approved, and motherland's traditional medicine culture is of extensive knowledge and profound scholarship, and Chinese medicine is under the guidance of theory of traditional Chinese medical science; Execute with dialectical that to control be principle of reatment, from the integral body sight, prescription flexibly; Can not only improve the clinical symptoms of high blood pressure, also can nurse one's health physical function, prevention and treatment complication.
Corn stigma (Zea mays L.) is one of time-honored Chinese medicine of China, records in " Chinese medicine promulgated by the ministries or commissions of the Central Government " (the 1st) and " Chinese pharmacopoeia version in 1977 is the style and the column cap of the beautiful another name for Sichuan Province of grass family platymiscium corn.It is sweet to distinguish the flavor of, and property is flat.Inducing diuresis for removing edema is arranged, hypotensive effect.For thousands of years, China to have formed the hundreds of kind be the Dietotherapy method of major ingredient with the corn stigma.Food and Drug Administration also confirms corn stigma safety, nontoxic, and the made medicine of its extract is a non-prescribed medicine.Its main component has flavones and glycoside, sterol, alkaloid, carbohydrate, organic acid, volatile oil, trace element and multivitamin etc.
The root of kudzu vine is written at present that " one one of Chinese pharmacopoeia version in 2005 is the dry root of legume pueraria lobata Pueraria lobata (Willd.) Ohwi.Sweet, hot, spleen, stomach warp are returned in cold.Have relieving muscles to expel heat, promote the production of body fluid, promoting eruption rises the function of positive antidiarrheal.Be used for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hot dysentery is had loose bowels; The hypertension neck pain.The root of kudzu vine has recorded into the medicine-food two-purpose article list of China Ministry of Public Health promulgation (defending the method prison sends out [2002] No. 51), in food, health food, is widely used.The major function composition is an osajin in the root of kudzu vine.
Chrysanthemum is written at present that " one one of Chinese pharmacopoeia version in 2005 is the dry capitulum of feverfew chrysanthemum Chrysanthemum mo-Rifolium Ramat..Sweet, bitter, be slightly cold, return lung, Liver Channel.Has diffusing wind heat-clearing, the effect that flat liver makes eye bright.Be used for anemopyretic cold, it is dizzy to have a headache, red eye, swell pain, and eyes is dim-sighted.Chrysanthemum has recorded into the medicine-food two-purpose article list of China Ministry of Public Health promulgation (defending the method prison sends out [2002] No. 51), in food, health food, is widely used.The major function composition is a general flavone.
Hawthorn is written at present that " one one of Chinese pharmacopoeia version in 2005 is the dry mature fruit of rosaceous plant large-fruited Chinese hawthorn Crataeguspinnatifida Bge.var.major N.E.Br or hawthorn Crataegus pinnatifida Bge..Sour, sweet, tepor.Return spleen, stomach, Liver Channel.Has food digesting stomach fortifying, the function of the diffusing stasis of blood of promoting the circulation of qi.Be used for carnivorous stagnating, the gastral cavilty turgor rushes down dysentery stomachache, and hemostasis is through closing stasis of blood resistance in postpartum, trusted subordinate's shouting pain, hernia pain; Hyperlipidemia.Hawthorn has been recorded into the medicine-food two-purpose article list of China Ministry of Public Health promulgation (defending the method prison sends out [2002] No. 51), in food, health food, is widely used.Its functional component mainly contains organic acid, flavonoids, trace element and multivitamin etc.
Lophatherum gracile is written at present that " one one of Chinese pharmacopoeia version in 2005 is the dry cauline leaf of grass lophatherum gracile Lophatherumgracile Brongn..Sweet, light, cold.The thoughts of returning home, stomach, small intestinl channel.Has clearing heat and relieving fidgetness, the effect of diuresis.Be used for the pyreticosis polydipsia, hot urination drenches pain, aphthae.Lophatherum gracile has been recorded into the medicine-food two-purpose article list of China Ministry of Public Health promulgation (defending the method prison sends out [2002] No. 51), in food, health food, is widely used.Its composition is mainly triterpenes and steroid class.
Still do not have corn stigma, the root of kudzu vine, chrysanthemum, hawthorn, lophatherum gracile compatibility at present and be applied to hypertensive relevant report.
Adopt separately corn stigma, separately adopt the root of kudzu vine, separately adopt chrysanthemum, separately adopt hawthorn, adopt lophatherum gracile that certain hypotensive effect is all arranged separately, but antihypertensive effect is general.Adopt the folk prescription step-down, also lack the comprehensive adjustment effect of the Chinese medicine compound prescription of integration of drinking and medicinal herbs.
Summary of the invention
The purpose of this invention is to provide a kind of is the health products of the aided blood pressure-lowering of main component with corn stigma, the root of kudzu vine, chrysanthemum, hawthorn, lophatherum gracile; The health drink of aided blood pressure-lowering particularly, this beverage has the effect of aided blood pressure-lowering.
Be in particular in that corn stigma, the root of kudzu vine, chrysanthemum, the hawthorn of compound prescription, the antihypertensive effect of lophatherum gracile are superior to the effect of folk prescription step-down.It is can not amplitude too big to bring high blood pressure down in addition, otherwise has a lot of negative influences, and the hypertension big rat group antihypertensive effect that the present invention is directed to model group is obvious and moderate.
A kind of health products of aided blood pressure-lowering, it is to be prepared from containing the following weight proportion raw material: corn stigma 1-30 part, root of kudzu vine 1-30 part, chrysanthemum 1-15 part, hawthorn 1-15 part, lophatherum gracile 1-15 part.
A kind of health drink of aided blood pressure-lowering, it is to be prepared from containing the following weight proportion raw material: corn stigma 1-30 part, root of kudzu vine 1-30 part, chrysanthemum 1-15 part, hawthorn 1-15 part, lophatherum gracile 1-15 part,
A kind of health drink of aided blood pressure-lowering, it is to be prepared from containing the following weight proportion raw material: corn stigma 1-30 part, root of kudzu vine 1-30 part, chrysanthemum 1-15 part, hawthorn 1-15 part, lophatherum gracile 1-15 part.
A kind of health products of aided blood pressure-lowering or health drink, it is to be prepared from containing the following weight proportion raw material: corn stigma 4-8 part, root of kudzu vine 4-8 part, chrysanthemum 2-4 part, hawthorn 1-2 part, lophatherum gracile 1-2 part.
The preparation method of health-care beverage of aided blood pressure-lowering of the present invention: corn stigma, the root of kudzu vine, chrysanthemum, hawthorn, lophatherum gracile raw material are extracted, filter, get extract; Dilution adds auxiliary material, mixing, sterilization, can.
The said auxiliary material of above-mentioned preparation method is auxiliary material or the complementary composition that allows adding in food or the health food
The present invention also provides the purposes of this health drink in treatment hypertension, and this health drink can also be used for illnesss such as supplemental treatment high fat of blood, hyperglycaemia.
Raw material prescription of the present invention is monarch drug in a prescription based on instruction of Chinese Medicine theory with the corn stigma, sharp water step-down; Promoting the production of body fluid with the root of kudzu vine rises sun, and liver is put down in the chrysanthemum heat-clearing, is ministerial drug altogether; Hawthorn goes into blood system and promoting blood circulation, and lophatherum gracile clears away heart-fire and lets out that fiery heat conduction is descending to be made for assistant altogether.At the same usefulness of medicine, play the merit of step-down altogether.Prove effectively aided blood pressure-lowering of medicine of the present invention through conventional pharmacological testing, also have auxiliary antilipemic, hypoglycemic effect concurrently, and do not have obvious toxic and side effects, be suitable for long-term edible.Because raw material of the present invention is the raw material of medicine-food two-purpose, so the present invention not only can be used as food, health food uses, and also can further develop and process medicine, to meet clinical needs.
Obviously, according to foregoing of the present invention,,, can also make modification, replacement or the change of other various ways not breaking away under the above-mentioned basic fundamental thought of the present invention prerequisite according to the ordinary skill knowledge and the customary means of this area.
Below, foregoing of the present invention is remake further detailed description through specific embodiment.But should this be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following instance.All technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
Specific embodiment
Embodiment 1
The preparation of health drink of the present invention: (1) raw material weight is: corn stigma 1.0kg, root of kudzu vine 1.0kg, chrysanthemum 0.5kg, hawthorn 0.25kg, lophatherum gracile 0.25kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and adds purified water and is diluted to 350L, adds white granulated sugar 10kg, mixing, 140 ℃ of sterilizations, can promptly gets.
Several the animal test results that formula for health beverage extract of the present invention is carried out are following:
1, hypotensive effect: kidney vascular type Hypertensive Rats is carried out drop test, and compare with each single medicinal material extract, the antihypertensive effect compound is better than folk prescription, sees table 1.
Table 1 hypotensive effect (n=10)
Figure S2008101068576D00042
2, effect for reducing fat: with the blood fat recovery capsule is contrast, and high fat mouse is measured blood lipids index in administration one all backs respectively, and the two effect for reducing fat is similar, sees table 2.
Table 2 effect for reducing fat (n=10)
Figure S2008101068576D00043
Figure S2008101068576D00051
3, blood sugar reducing function: with the diabetes pill is contrast, to alloxan cause diabetic mice respectively administration measure blood sugar after 30 days, the two blood sugar reducing function is similar, sees table 3.
Table 3 blood sugar reducing function (n=10)
Figure S2008101068576D00052
Figure S2008101068576D00053
The amplitude of step-down, lipopenicillinase, hypoglycemic can not be big especially, otherwise possibly cause other negative effects again on the contrary.Above-mentioned data are illustrated in the receptible amplitude range, and the step-down of Chinese medicine compound prescription, lipopenicillinase, hypoglycemic effect all are superior to folk prescription.
Embodiment 2
Preparation of the present invention: (1) raw material weight is: corn stigma 1.0kg, root of kudzu vine 0.5kg, chrysanthemum 0.5kg, hawthorn 0.5kg, lophatherum gracile 0.5kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and adds purified water and is diluted to 350L, adds Aspartame 100g, mixing, 140 ℃ of sterilizations, can promptly gets the health drink of aided blood pressure-lowering.
Embodiment 3
Preparation of the present invention: (1) raw material weight is: corn stigma 1.5kg, root of kudzu vine 1.0kg, chrysanthemum 0.2kg, hawthorn 0.15kg, lophatherum gracile 0.15kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and adds purified water and is diluted to 350L, adds stevioside 100g, mixing, 140 ℃ of sterilizations, can promptly gets the health drink of aided blood pressure-lowering.
Embodiment 4
Preparation of the present invention: (1) raw material weight is: corn stigma 1.5kg, root of kudzu vine 0.5kg, chrysanthemum 0.5kg, hawthorn 0.25kg, lophatherum gracile 0.25kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and adds purified water and is diluted to 350L, adds acesulfame potassium 100g, mixing, 140 ℃ of sterilizations, can promptly gets the health drink of aided blood pressure-lowering.
Embodiment 5
Preparation of the present invention: (1) raw material weight is: corn stigma 1.5kg, root of kudzu vine 1.0kg, chrysanthemum 0.3kg, hawthorn 0.1kg, lophatherum gracile 0.1kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and adds purified water and is diluted to 350L, adds maltitol 10kg, mixing, 140 ℃ of sterilizations, can promptly gets the health drink of aided blood pressure-lowering.
Embodiment 6
Preparation of the present invention: (1) raw material weight is: corn stigma 1kg, root of kudzu vine 1kg, chrysanthemum 1kg, hawthorn 1kg, lophatherum gracile 1kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and adds purified water and is diluted to 500L, adds acesulfame potassium 100g, mixing, 140 ℃ of sterilizations, can promptly gets the health drink of aided blood pressure-lowering.
Embodiment 7
Preparation of the present invention: (1) raw material weight is: corn stigma 30kg, root of kudzu vine 30kg, chrysanthemum 15kg, hawthorn 15kg, lophatherum gracile 15kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and adds purified water and is diluted to 10000L, adds acesulfame potassium 800g, mixing, 140 ℃ of sterilizations, can promptly gets the health drink of aided blood pressure-lowering.
Embodiment 8
Preparation of the present invention: (1) raw material weight is: corn stigma 6kg, root of kudzu vine 3kg, chrysanthemum 2kg, hawthorn 2kg, lophatherum gracile 2kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and adds purified water and is diluted to 1500L, adds Aspartame 400g, mixing, 140 ℃ of sterilizations, can promptly gets the health drink of aided blood pressure-lowering.
Embodiment 9
Preparation of the present invention: (1) raw material weight is: corn stigma 6kg, root of kudzu vine 3kg, chrysanthemum 2kg, hawthorn 2kg, lophatherum gracile 2kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and spray-drying obtains dry powder 1.2kg, adds PVPP 60g, Aspartame 10g, mixing, compressing tablet promptly gets the sheet shape health products of aided blood pressure-lowering.
Embodiment 10
Preparation of the present invention: (1) raw material weight is: corn stigma 4kg, root of kudzu vine 4kg, chrysanthemum 2kg, hawthorn 1k g, lophatherum gracile 1kg; (2) above-mentioned raw materials is added 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merges, and spray-drying obtains dry powder 0.9kg, adds Aspartame 10g, and mixing in the hard shell capsules of packing into, promptly gets the hard shell capsules health products of aided blood pressure-lowering.

Claims (4)

1. the health products of an aided blood pressure-lowering, it is characterized in that: it is to be prepared from the following weight proportion raw material:
Corn stigma 4-8 part, root of kudzu vine 4-8 part, chrysanthemum 2-4 part, hawthorn 1-2 part, lophatherum gracile 1-2 part; Add 10 times of water gagings and decoct 2 times, each 1 hour, filter, filtrating merge the active component extract.
2. the health drink of an aided blood pressure-lowering, it is characterized in that: it is to be prepared from the following weight proportion raw material:
Corn stigma 4-8 part, root of kudzu vine 4-8 part, chrysanthemum 2-4 part, hawthorn 1-2 part, lophatherum gracile 1-2 part; With corn stigma, the root of kudzu vine, chrysanthemum, hawthorn and Herba Lophatheri extract is active component, adds the auxiliary material of permission adding in food or the health food or the beverage that complementary composition is prepared from;
It comprises following steps: corn stigma, the root of kudzu vine, chrysanthemum, hawthorn and lophatherum gracile is added 10 times of water gagings decocts 2 times, and each 1 hour, filter, filtrating merges, and gets extract; Dilution, mixing, sterilization, can.
3. the application of the described aided blood pressure-lowering health drink of claim 2 in the hypertensive medicine of preparation treatment, health food.
4. the described aided blood pressure-lowering health drink of claim 2 is in preparation treatment high fat of blood, the medicine of hyperglycaemia, the application in the health food.
CN2008101068576A 2008-05-15 2008-05-15 Aided blood pressure-lowering health drink and preparation method and usage thereof Expired - Fee Related CN101444296B (en)

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CN101692923B (en) * 2009-08-20 2012-07-04 杭州六易科技有限公司 Making method of blood sugar regulating beverage
CN103519305B (en) * 2013-10-17 2015-01-28 浏阳河农业产业集团股份有限公司 Sweet corn low-sugar composite type beverage and preparation method thereof
CN103549437B (en) * 2013-11-22 2015-04-29 云南蓝钻生物科技股份有限公司 Health-protection food capable of reducing blood pressure and blood fat and preparation method of food
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CN105617116A (en) * 2016-03-21 2016-06-01 武汉工程大学 Cyclocarya paliurus foot-bathing composition for treating high blood pressure, high blood sugar and high blood lipid and preparation method of cyclocarya paliurus foot-bathing composition
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