CN101433332B - Food replenisher for improving function of intestinal canal, moistening intestines and relaxing the bowels, and preparation method thereof - Google Patents

Food replenisher for improving function of intestinal canal, moistening intestines and relaxing the bowels, and preparation method thereof Download PDF

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CN101433332B
CN101433332B CN2008102326236A CN200810232623A CN101433332B CN 101433332 B CN101433332 B CN 101433332B CN 2008102326236 A CN2008102326236 A CN 2008102326236A CN 200810232623 A CN200810232623 A CN 200810232623A CN 101433332 B CN101433332 B CN 101433332B
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intestinal canal
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杨建伟
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Abstract

The invention relates to a food supplement for improving the intestinal function and relaxing bowel, which consists of the following raw materials in percentage by weight: a. 5 to 90 percent of fructo-oligosaccharide, 5 to 90 percent of mannitol and 0.1 to 10 percent of Tibet seabuckthorn juice (calculated on dry basis); or the food supplement consists of the following raw materials in percentage by weight: 10 to 90 percent of fructo-oligosaccharide and 10 to 90 percent of mannitol. The preparation method b is as follows: the materials of a are mixed, crushed, filtered by a 100 meshes of sieve, and prepared into soft materials by 90 to 95 percent ethanol; the soft materials are sieved by a 16 or 14 meshes of sieve and prepared into wet particles; and the wet particles are dried at a constant temperature of between 60 and 80 DEG C, subjected to tight subpackage by damp-proof packing, and can be prepared into granular formulation or powder or an oral liquid. The recommended health-care dosage of the food supplement is 3 to 20 grams of the active food supplement taken each day, and the food supplement is suitable for various groups. The food supplement is functional food for improving the intestinal function, relaxing bowel and preventing and treating constipation by improving the physical property and the micro-ecological environment of the gastrointestinal tract through oral taking.

Description

Improve food supplement that function of intestinal canal relaxes bowel and preparation method thereof
Technical field
The present invention relates to improve the food supplement that function of intestinal canal relaxes bowel.Be specifically related to a kind of food supplement that contains FOS, improve enteron aisle physical property and micro-ecological environment by oral, thus reach improve function of intestinal canal, relax bowel, the anti-functional food that treats constipation.
Background technology
Along with development and the growth in the living standard of society, people's work rhythm is more and more faster, and health problem such as constipation, fatigue and high fat of blood etc. are also perplexing people thereupon.People improve quality of life in the urgent need to a kind of nutriment that can eliminate simultaneously multiple adverse health situation.Enteron aisle is the vitals that human consumption absorbs, and is people's the foundation of acquired constitution.The constipation that mostly is that the function of intestinal canal that affects the people is normally brought into play, brought many miseries to people.Modal constipation is chronic functional constipation.Chronic functional constipation refers to that non-structural disease becomes the stool that causes and discharges difficulty, and just matter is dry, hard, constipated obstructed, involved and abstruse not smooth, though defecation frequency reduces or infrequent defecation time lengthening or awareness of defecation is arranged and discharge difficulty, the permanent illness of the course of disease.This sick incidence of disease is with age growth and increases progressively trend, and the rural area is higher than the city, and the north is higher than south, and the women is higher than the male sex.Prolonged constipation can cause the complication such as hemorrhoid, anal fissure, for general disease, especially on the impact of cardiovascular and cerebrovascular diseases, has caused people's common concern.
At present, the control chronic functional constipation is main mainly with medicine: 1. irritant laxative: directly act on intestinal mucosa, enterocinesia is strengthened and promote defecation.2. bulk cathartic: mainly contain the high osmosis salt, these ions are difficult for being absorbed by intestinal mucosa, and oral rear intestinal contents osmotic pressure raises, and will suck enteric cavity in the moisture self-organizing, make that water content increases in the ight soil.3. the swollen property cathartic of Peng: contain multiple in intestines seldom digestion or indigestible plant and semisynthetic fibre element, enter imbibition agglutination behind the enteron aisle, the intestinal contents volume is increased, and is rich in moisture, reflectivity ground increases enterocinesia and defecation.4. emollient cathartic (stool softener): direct lubricated intestinal tube, make ight soil be easy to by.5. surfactant very: can reduce the surface tension of liquid, moisture is entered ight soil, makes it softening.But the cathartic ubiquity and is caused electrolyte disturbance, affects micro-ecological environment in the enteron aisle, causes the side effect such as drug dependence, can not use for a long time; Some prevent that the commercially available health products effect of constipation is not remarkable.
Summary of the invention
The object of the invention is in order to solve the weak point of above-mentioned prior art, can relax bowel and provide a kind of, can improve again the functional food that contains FOS of the multi-function health-care effect of intestine microenvironment and function, adjusting blood fat, antifatigue, formulation is granule, loose (powder) agent or oral liquid.
Technical scheme of the present invention is: improve the food supplement that function of intestinal canal relaxes bowel, it is characterized in that, it is to be by percentage by weight: 5%~90% FOS, 5%~90% sweet mellow wine forms by 0.1%~10% Fructus Hippophae thibetanae of giving money as a gift (Hippophae thibetana Schlechtend.) fruit Normal juice.
The described preparation method who improves the food supplement that function of intestinal canal relaxes bowel: it is characterized in that; mixing of materials with aforementioned proportion; through pulverizing 100 mesh sieves; with 90~95% ethanol softwood processed; use granulator to cross 16 or 14 mesh sieves and make wet granular; 60~80 ℃ of freeze-day with constant temperature, damp-prrof packing thing carry out the agent of tight packing granulation.
The described preparation method who improves the food supplement that function of intestinal canal relaxes bowel is characterized in that with above-mentioned mixing of materials, through pulverizing 100 mesh sieves, the damp-prrof packing thing carries out tight packing, namely makes loose or pulvis.
The described preparation method who improves the food supplement that function of intestinal canal relaxes bowel is characterized in that, with above-mentioned material dissolved in distilled water, it is an amount of to add bacteriostatic agent, filters, aseptic subpackaged, makes oral liquid.
Advantage of the present invention and effect are: of the present inventionly improve the food supplement that function of intestinal canal relaxes bowel, it is the food supplement that contains FOS, improve intestines and stomach physical property and micro-ecological environment by oral, improve that function of intestinal canal relaxes bowel, the anti-functional food that treats constipation thereby reach.
Below in conjunction with specific embodiment the present invention is described in further detail.
The specific embodiment
Of the present inventionly improve the food supplement that function of intestinal canal relaxes bowel, it is to be by percentage by weight: 5%~90% FOS, 5%~90% sweet mellow wine forms by 0.1%~10% Fructus Hippophae thibetanae of giving money as a gift (Hippophae thibetana Schlechtend.) fruit Normal juice.
The described preparation method who improves the food supplement that function of intestinal canal relaxes bowel: with the mixing of materials of aforementioned proportion; through pulverizing 100 mesh sieves; with 90~95% ethanol softwood processed; use granulator to cross 16 or 14 mesh sieves and make wet granular; 60~80 ℃ of freeze-day with constant temperature, damp-prrof packing thing carry out the agent of tight packing granulation.
The described preparation method who improves the food supplement that function of intestinal canal relaxes bowel, with above-mentioned mixing of materials, through pulverizing 100 mesh sieves, the damp-prrof packing thing carries out tight packing, namely makes loose or pulvis.
The described preparation method who improves the food supplement that function of intestinal canal relaxes bowel, with above-mentioned material dissolved in distilled water, it is an amount of to add bacteriostatic agent, filters, aseptic subpackaged, makes oral liquid.
The health care RD of food supplement of the present invention is to take above-mentioned active food supplement 3 grams every day to 20 grams, is applicable to all kinds of crowds.
Of the present inventionly improve the food supplement that function of intestinal canal relaxes bowel.Be the food supplement that contains FOS, improve intestines and stomach physical property and micro-ecological environment by oral, improve that function of intestinal canal relaxes bowel, the anti-functional food that treats constipation thereby reach.
FOS is the natural activity composition that is present in fruit, vegetables, the honey and other substances, good water-soluble dietary fiber.As a kind of new resource food raw material, through further investigation for many years, in the world many countries (comprising China) clearly confirm FOS to improve function of intestinal canal, anti-treat constipation and suffer from diarrhoea, reduce blood fat, to improve the effects such as body immunity remarkable.Its mechanism of action has two: the first, FOS is because its unique structure, the not hydrochloric acid in gastric juice in digested road and enzymic digestion, and large intestine can go directly, by the rapidly selective absorption of human body beneficial's flora Bifidobacterium, Bifidobacterium is bred rapidly, and produce SCFA, make enteron aisle pH value deflection acid, suppress the growth of pernicious bacteria, reduce simultaneously the activity of some harmful reductase, reduce generation and the accumulation of the interior carcinogenic substance of enteron aisle and Toxic Metabolites, really play the effect of removing enteron aisle rubbish.The second, FOS is a kind of water-soluble dietary fiber, and long-term taking can reduce serum cholesterol, improves lipid-metabolism.
Sweet mellow wine is a kind of monose, extensive application on food and medicine.Pharmaceutically be good diuretics, also as the diluent of the excipient of tablet and solid, liquid.Sweet mellow wine in food as sweetener or the antitack agent of sugar-free chewing gum, filler, quality improver, anticaking agent.In addition, it also can make an addition to various food to prolong its shelf life.Sweet mellow wine is in vivo by metabolism, do not absorbed by enteron aisle after oral, forms hyperosmotic state in intestines are suitable, stops the absorption of moisture in the enteron aisle, makes that moisture increases in the enteron aisle, and the enteric cavity volume increases, and enteron aisle is expanded, and reflectivity stimulation enterocinesia reaches the purpose of defecation.20% mannitol solution heavy dose commonly used is oral as the enteron aisle preparation before performing the operation or before the intestinal inspection clinically.The sweet mellow wine action temperature and, be difficult for to produce the complication such as diarrhoea, stomachache, old and weak patient also can use, and has solved constipation person's misery, without toxicity, successful.
Fructus Hippophae thibetanae (Hippophae thibetana Schlechtend.) is Elaeangnaceae Hippophne undershrub, NATURAL DISTRIBUTION in Tibet, Qinghai, Sichuan, be a kind of plant that has unique nutrition and medical value at extremely frigid zones.Its fruit is rich in vitamin, polysaccharide, former blue and white element, flavones, the multiple effective ingredient of sea-buckthorn wet goods, it has anti-inflammatory, pain relieving, sterilization, promote the effect of regeneration, in radioresistance, anticancer change, anti-ageing, balance the body immunologic function, adjust gastrointestinal function, relieving dyspepsia, improve a poor appetite, alleviate artery sclerosis, the aspects such as control cardiovascular and cerebrovascular disease all have preferably effect, are that the local masses prevent and cure diseases, the important medicine-food two-purpose resource of rehabilitation.
Embodiment 1
Prescription:
Figure GSB00000901716700041
Figure GSB00000901716700051
Method for making: with above-mentioned mixing of materials, through pulverizing 100 mesh sieves, with 90~95% ethanol softwood processed, use granulator to cross 16 or 14 mesh sieves and make wet granular, 60~80 ℃ of freeze-day with constant temperature, the damp-prrof packing thing carries out tight packing, and get final product.
Embodiment 2
Prescription:
Figure GSB00000901716700052
Method for making: with above-mentioned mixing of materials, through pulverizing 100 mesh sieves, the damp-prrof packing thing carries out tight packing, and get final product.
Embodiment 3
Prescription:
Figure GSB00000901716700053
Method for making: with above-mentioned material dissolved in distilled water, it is an amount of to add bacteriostatic agent, and adding distil water to 1000 milliliter is aseptic subpackaged, and get final product.
Embodiment 4
Prescription:
Figure GSB00000901716700061
Method for making: with above-mentioned mixing of materials, through pulverizing 100 mesh sieves, with 90~95% ethanol softwood processed, use granulator to cross 16 or 14 mesh sieves and make wet granular, 60~80 ℃ of freeze-day with constant temperature, the damp-prrof packing thing carries out tight packing, and get final product.
Embodiment 5
Prescription:
FOS 100 grams
Sweet mellow wine 900 grams
Make: 1000 grams
Method for making: with above-mentioned mixing of materials, through pulverizing 100 mesh sieves, with 90~95% ethanol softwood processed, use granulator to cross 16 or 14 mesh sieves and make wet granular, 80 ℃ of freeze-day with constant temperature, the damp-prrof packing thing carries out tight packing, and get final product.
Embodiment 6
Prescription:
FOS 900 grams
Sweet mellow wine 100 grams
Make: 1000 grams
Method for making: with above-mentioned mixing of materials, through pulverizing 100 mesh sieves, with 90~95% ethanol softwood processed, use granulator to cross 16 or 14 mesh sieves and make wet granular, 80 ℃ of freeze-day with constant temperature, the damp-prrof packing thing carries out tight packing, and get final product.
Embodiment 7
Prescription:
Sweet mellow wine 900 grams
Fructus Hippophae thibetanae fruit Normal juice (by giving money as a gift) 100 grams
Make 1000 grams
Method for making: with above-mentioned mixing of materials, through pulverizing 100 mesh sieves, with 90~95% ethanol softwood processed, use granulator to cross 16 or 14 mesh sieves and make wet granular, 60 ℃ of freeze-day with constant temperature, the damp-prrof packing thing carries out tight packing, and get final product.

Claims (2)

1. one kind is improved the food supplement that function of intestinal canal relaxes bowel, it is characterized in that, it is to be by percentage by weight: 5%~90% FOS, 5%~90% sweet mellow wine forms by 0.1%~10% Fructus Hippophae thibetanae of giving money as a gift (Hippophae thibetana Schlechtend.) fruit Normal juice.
2. the described preparation method who improves the food supplement that function of intestinal canal relaxes bowel according to claim 1: it is characterized in that; mixing of materials with aforementioned proportion; through pulverizing 100 mesh sieves; with 90~95% ethanol softwood processed; use granulator to cross 16 or 14 mesh sieves and make wet granular; 60~80 ℃ of freeze-day with constant temperature, damp-prrof packing thing carry out the agent of tight packing granulation.
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CN103689748B (en) * 2013-12-20 2015-08-19 北京工商大学 One has adjustment intestines and stomach function, the anti-washing drink treated constipation
US10111923B2 (en) 2015-04-29 2018-10-30 Infinitus (China) Company Ltd Compositions comprising Cyclocarya paliurus extract and preparation method and uses thereof
CN111096989B (en) * 2018-10-25 2021-12-03 陕西康达福医药科技有限公司 Composition for treating functional constipation and preparation method and application thereof
CN109259005A (en) * 2018-11-27 2019-01-25 江苏朸健生命科技发展有限公司 Beverage composition for treating dental erosion, liquid beverage and preparation method thereof
CN110075203A (en) * 2019-05-30 2019-08-02 周国洪 A kind of composition of coordinating intestines and stomach, reinforcing spleen to promote digestion, prevention and treatment aphtha and constipation repeatedly
CN112386577B (en) * 2019-08-16 2024-01-23 北京天衡药物研究院有限公司 Composition for treating constipation
CN112544920A (en) * 2020-12-03 2021-03-26 山东腾贵医药有限公司 Composition for improving constipation and preparation method thereof

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