CN101428117A - Medicament for invigorating pulse and reducing adipose, and preparation method thereof - Google Patents
Medicament for invigorating pulse and reducing adipose, and preparation method thereof Download PDFInfo
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- CN101428117A CN101428117A CNA2008102196660A CN200810219666A CN101428117A CN 101428117 A CN101428117 A CN 101428117A CN A2008102196660 A CNA2008102196660 A CN A2008102196660A CN 200810219666 A CN200810219666 A CN 200810219666A CN 101428117 A CN101428117 A CN 101428117A
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Abstract
The invention relates to a drug for promoting blood circulation and lowering lipid and a preparation method thereof, and the drug takes rattan tea extract powder, lucid ganoderma extract powder, American ginseng, sanchi powder, dendrobium, spirulina platensis and propolis as raw materials. The preparation method is as follows, the herbal medicines after the smashing, the solvent extraction and other pretreatments are allocated according to the proportion, the baking and the removal of fire-toxin are carried out, and then the herbal medicines are packaged into powder, capsules, blocks or prepared into wine in a sterile room. The drug has the effects of lowering blood lipid and blood sugar, regulating blood pressure, benefiting qi, promoting blood circulation, removing phlegm, benefiting collaterals, suppressing hyperactive liver, nourishing heart, improving body immunity, improving sleep, improving gastrointestinal function and improving sub-health.
Description
Technical field
The present invention relates to a kind of medicine of function of invigorating circulation and reducing blood fat.Be the Chinese patent medicine of feedstock production specifically, the invention still further relates to the preparation method of this medicine with the Chinese herbal medicine.
Background technology
Hyperlipidemia is the main hazard factor that causes human atherosclerosis, in recent years, along with people's living standard improves constantly, the variation of dietary structure and life style, crowd's blood lipid level is raising generally year by year.The heart infarction that China causes because of hyperlipidemia every year, cerebral infarction, apoplexy, hemiplegia, the number that disables, causes death rise with the speed of average annual growth 12%.
Hyperlipoidemia causes " blood is thick " easily, deposits on blood vessel, forms little " speckle " (being exactly " atherosclerosis " that we often say), and these " speckle " artery-cloggings interrupt blood.If this situation occurs in heart, will cause coronary heart disease; Occur in brain, apoplexy will occur; If occur in lower limb, will cause limb necrosis.Hyperlipidemia also can cause multiple diseases such as hypertension, diabetes, sexual dysfunction, alzheimer disease, pancreatitis, liver cirrhosis.Scientist's latest find: hyperlipidemia also can bring out cancer.It is clinical show as dizziness, dizzy, uncomfortable in chest, drowsiness, breathe hard, fatigue and asthenia, limb or refer to fiber crops, dimly pale tongue or have that petechiae, tongue are greasy in vain, stringy and rolling pulse etc.
Chinese patent CN1879742A is the soft capsule preparation that raw material is made with Radix Scorzonerae Albicaulis, Rhizoma Chuanxiong, Folium Nelumbinis, Radix Notoginseng, Pericarpium Zanthoxyli, and Chinese patent CN1927301A is that raw material is made dispersible tablet with Radix Scorzonerae Albicaulis, Rhizoma Chuanxiong, Folium Nelumbinis, Radix Notoginseng, Pericarpium Zanthoxyli.
Medicine of the present invention is a raw material with Ampelopsis grossedentata cream powder, glossy ganoderma ointment powder, Radix Panacis Quinquefolii, Radix Notoginseng powder, Herba Dendrobii, spirulina, propolis, can reduce hyperlipidemia and hypertension fast, and stable curative effect, toxic and side effects are little.
Summary of the invention
The purpose of this invention is to provide that a kind of blood fat reducingization is turbid, the medicine of blood circulation and channel invigorating.
Another object of the present invention provides the preparation method of this medicine.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to hyperlipidemia, achieve with reference to modern pharmacological research, from motherland's medicine treasure-house, filter out blood fat reducing and blood glucose, transfer blood pressure, benefiting QI for activating blood circulation, sharp network reduces phlegm, suppressing the hyperactive liver nourishes heart, human body immunity improving power, improve sleep, improve the natural edible-plant medicine of gastrointestinal function and subhealth state, by the theory of Chinese medical science prescription, skim the cream off milk, make it except the effect of performance blood fat reducing, can also transfer blood pressure, benefiting QI for activating blood circulation, sharp network reduces phlegm, suppressing the hyperactive liver nourishes heart, human body immunity improving power, improve sleep, improve gastrointestinal function and subhealth state.
The medicament that medicine of the present invention is made by the following weight proportion raw material: Ampelopsis grossedentata cream powder 10-25, glossy ganoderma ointment powder 10-25, Radix Panacis Quinquefolii 10-25, Radix Notoginseng powder 10-20, Herba Dendrobii 10-25, spirulina 10-20, propolis 5-15.
The weight proportion of each raw material is preferably: Ampelopsis grossedentata cream powder 18-23, glossy ganoderma ointment powder 18-23, Radix Panacis Quinquefolii 18-23, Radix Notoginseng powder 10-15, Herba Dendrobii 15-20, spirulina 10-15, propolis 5-10.
Weight proportion the best of medicine of the present invention is Ampelopsis grossedentata cream powder 20, glossy ganoderma ointment powder 20, Radix Panacis Quinquefolii 20, Radix Notoginseng powder 10, Herba Dendrobii 15, spirulina 10, propolis 5.
The preparation method of function of invigorating circulation and reducing blood fat medicine is characterized in that preparing the function of invigorating circulation and reducing blood fat medicine and comprises the following steps:
With Radix Panacis Quinquefolii, Radix Notoginseng powder, Herba Dendrobii, spirulina, propolis is inserted in the Highefficientpulverizer respectively and is pulverized, cross 100 mesh sieves, then medicated powder is inserted in the stainless steel disc and evenly separate, put into the high temperature baking box, temperature is controlled at 50 degree, toasted 2 hours, stir evenly once wherein per half an hour, taking-up is put into Stainless steel basin and is removed fire-toxin, add Ampelopsis grossedentata cream and glossy ganoderma ointment and carry out the pulverizing second time, cross 120 mesh sieves, the medicated powder that sieves is for the second time continued to put into the sterilization of high temperature baking box, temperature is controlled at 60 degree, toasted 2 hours, stir evenly once per half an hour, takes out and put into Stainless steel basin at aseptic removal fire-toxin, treat that fire-toxin carries out packing after clean, also can make capsule or be compressed into block preparation.
The extracting method of Ampelopsis grossedentata cream is as follows:
1. merceration: take by weighing Ampelopsis grossedentata 1Kg, be cut into the cataclasm of 3-5 centimeter length earlier, with the pure rice wine 5000ml of cataclasm adding 60 degree, 72 hours after-filtration are soaked in sealing then, and filtrate is concentrated;
2. hot dipping: the previous step filtering residue continues to add the pure rice wine 5000ml of 60 degree, heating in water bath refluxed 2 hours, clock from boiling, so operation is twice, the merging of above-mentioned three times filtrate is concentrated into no ethanol, this concentrated solution is transferred in the 5000ml distilling apparatus, dilute from distillation and reflux device moving valve adding distilled water topmost to 2000ml, the reheat dissolving, placement is spent the night;
3. thermosol: previous step has solid and separates out after placing and spending the night, and filters, and filtrate is abandoned it, and filtering residue continues to add the 900ml hot water dissolving and places and spend the night;
4. purify and concentrate: after previous step is placed and spent the night, have solid to separate out, slowly filter, filtrate is abandoned it, the filtering residue adding distil water is to 1000ml, it is muddy until transparent nothings of solution that heating makes it dissolving, filtered while hot after the dissolving, and filtrate is transferred in the big stainless steel cask adding distil water to 2000ml, make it to keep liquid not seethe with excitement with the electric furnace heating, place then and spend the night, repeat aforesaid operations three times, soon concentrated solution places Rotary Evaporators to be concentrated into 1000ml and gets semi-finished product; Attention: heating-up temperature is unsuitable too high, can pull out furnace power if any boiling, gets final product with residual heat insulation, slowly filters while hot after having stirred, and can not once all pour liquid into funnel, in case the too low sample of temperature is separated out.After second and third time activated carbon adsorption, place the gained supernatant that spends the night and to repeat to use, because of wherein still containing small amount of sample, so had better not outwell as water.
5. dry: 50 ℃ of about finished products that got final product in a day of oven dry, stand-by.
The extracting method of glossy ganoderma ointment is as follows:
1. merceration: get Ganoderma 1Kg, next step after the rice wine 3000ml sealing that then broken end is added 50 degree is soaked 72 hours, is continued in broken end;
2. hot dipping: again with rice wine 2000ml, heating in water bath refluxed 2 hours with the Ganoderma soak, clocked from boiling, so operated twice, and the merging of above-mentioned three times filtrate is concentrated into no ethanol, places Rotary Evaporators to be concentrated into 1000ml last concentrated solution again;
3. dry: 50 ℃ of oven dry got final product in one day finished product, stand-by.
An important feature of the present invention is to contain abundant health-care components in the medicament, not only can blood fat reducing, also have blood sugar lowering, benefiting QI for activating blood circulation, the sharp network that reduces phlegm, suppressing the hyperactive liver nourish heart, human body immunity improving power, improve sleep, transfer blood pressure, improve the function of gastrointestinal function and subhealth state, this medicine can also be made lipid-lowering and healthcare liquor, with rice wine as solvent, make a kind of medicated wine, contain 20g medicine of the present invention in every 100ml rice wine.
Side's medicine composition is introduced:
Ampelopsis grossedentata: the Ampelopsis grossedentata effective ingredient is a flavonoid etc., and this medical instrument has pharmacological action widely, can strengthen, regulate immunity, and antiinflammatory is antibiotic, blood sugar lowering, and blood fat reducing, blood pressure lowering protects the liver, hepatoprotective, antioxidation, antitumor;
Ganoderma powder: but the strengthening immune system function, prophylaxis of tumours and cancer; Bring high blood pressure down prevention cardiovascular diseases's generation; Stimulate secretion of insulin, blood sugar lowering concentration.Improve allergic constitution, the dephlogistication symptom; Cholesterol reducing is avoided sclerosis of blood vessels; Strengthen liver function, perfect Alimentary running and enhance metabolism, eliminate interior free yl, prevent cell senescence;
Radix Panacis Quinquefolii: increase immunologic function; Enhance metabolism; Strengthen the mobility of cardiac muscle and enhancing heart; Calmness and antialcoholism action; The hypermnesis ability has remarkable efficacy to the Alzheimer; Adjust blood pressure; Physical strength reinforcing; Encourage digestion, the improvement effect arranged chronic gastropathy and the intestines and stomach are weak.
Radix Notoginseng powder: have the effect of immunomodulator and nourishing, strong, anti-aging effects, can reduce cholesterolemia, effective ingredient has certain protection and therapeutical effect to the kinds of experiments liver damage.
Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.The traditional Chinese medical science is always the principal agent of Herba Dendrobii as treatment " cloudy impairment of body fluid loses, xerostomia excessive thirst, lack of appetite is done, deficiency-heat after being ill, poor vision ".
Spirulina: regulate physiological function; The activate immunity function; The blood fat-reducing blood pressure-decreasing function; Recover hematopoietic function; Special body health effect.
Propolis: enhancing human body immunity function; Promote tissue regeneration; Blood pressure lowering, blood fat reducing; Antitumor, antiulcer, antioxidation; Hepatoprotective; Strengthen thin pleura, activating cell; Analgesia, local anesthesia; Antiinflammatory, sterilization, antibiotic, antitoxin.
Instructions of taking: 0.2 gram/time, day clothes 2 times, ante cibum, boiled water was taken after mixing it with water or the each 20～30ml of clofibrate pressing wine, and day clothes are once.Clinical experiment effect such as table 1, table 2 are taken biochemical investigation index ALT behind the medicine, GLU, TG, TC, BUNT, LAC and TCO as can be seen from Table 1
2All drop to normal value (P＜0.05), dizziness, feeling of fullness in the head, insomnia, hypertension all make moderate progress the ambition painful abdominal mass person of hiding from cure rate 100% as can be seen by table 2 clinicing symptom observation statistical table.
Table 1 biochemistry detection cross-reference table
Table 2 clinicing symptom observation statistical table
The specific embodiment
Embodiment
Take by weighing raw material (kilogram) by following proportioning:
Ampelopsis grossedentata cream powder 18, glossy ganoderma ointment powder 18, Radix Panacis Quinquefolii 18, Radix Notoginseng powder 9, Herba Dendrobii 13.5, spirulina 9, propolis 4.5.
Production method is as follows:
With Radix Panacis Quinquefolii, Radix Notoginseng powder, Herba Dendrobii, spirulina, propolis is inserted in the Highefficientpulverizer respectively and is pulverized, cross 100 mesh sieves, then medicated powder is inserted in the stainless steel disc and evenly separate, put into the high temperature baking box, temperature is controlled at 50 degree, toasted 2 hours, stir evenly once wherein per half an hour, and taking-up is put into Stainless steel basin and removed fire-toxin, add Ampelopsis grossedentata cream and glossy ganoderma ointment and carry out the pulverizing second time, cross 120 mesh sieves, the medicated powder that sieves is for the second time continued to put into the sterilization of high temperature baking box, temperature is controlled at 60 degree, toasted 2 hours, stir evenly once per half an hour, takes out and put into Stainless steel basin at aseptic removal fire-toxin, treats that fire-toxin makes powder after clean.
Claims (8)
1. a function of invigorating circulation and reducing blood fat medicine is characterized in that it is the medicament of being made by the following weight proportion raw material: Ampelopsis grossedentata cream powder 10-25, glossy ganoderma ointment powder 10-25, Radix Panacis Quinquefolii 10-25, Radix Notoginseng powder 10-20, Herba Dendrobii 10-25, spirulina 10-20, propolis 5-15.
2. the described function of invigorating circulation and reducing blood fat medicine of claim 1 is characterized in that the weight proportion of each raw material is preferably: Ampelopsis grossedentata cream powder 18-23, glossy ganoderma ointment powder 18-23, Radix Panacis Quinquefolii 18-23, Radix Notoginseng powder 10-15, Herba Dendrobii 15-20, spirulina 10-15, propolis 5-10.
3. the described function of invigorating circulation and reducing blood fat medicine of claim 1 is characterized in that each constituent proportioning the best is Ampelopsis grossedentata cream powder 20, glossy ganoderma ointment powder 20, Radix Panacis Quinquefolii 20, Radix Notoginseng powder 10, Herba Dendrobii 15, spirulina 10, propolis 5.
4. claim 1,2 or 3 described function of invigorating circulation and reducing blood fat medicines is characterized in that described medicament is powder, medicated wine, capsule or piece agent.
5. the preparation method of function of invigorating circulation and reducing blood fat medicine is characterized in that preparing the function of invigorating circulation and reducing blood fat medicine and comprises the following steps:
With Radix Panacis Quinquefolii, Radix Notoginseng powder, Herba Dendrobii, spirulina, propolis is inserted in the Highefficientpulverizer respectively and is pulverized, cross 100 mesh sieves, then medicated powder is inserted in the stainless steel disc and evenly separate, put into the high temperature baking box, temperature is controlled at 50 degree, toasted 2 hours, stir evenly once wherein per half an hour, and taking-up is put into Stainless steel basin and removed fire-toxin, add Ampelopsis grossedentata cream and glossy ganoderma ointment and carry out the pulverizing second time, cross 120 mesh sieves, the medicated powder that sieves is for the second time continued to put into the sterilization of high temperature baking box, temperature is controlled at 60 degree, toasted 2 hours, stir evenly once per half an hour, takes out and put into Stainless steel basin at aseptic removal fire-toxin, treats that fire-toxin carries out packing after clean.
6. the preparation method of the described function of invigorating circulation and reducing blood fat medicine of claim 5 is characterized in that the extracting method of described Ampelopsis grossedentata cream powder is as follows:
1. merceration: take by weighing Ampelopsis grossedentata 1Kg, be cut into the cataclasm of 3-5 centimeter length earlier, with the pure rice wine 5000ml of cataclasm adding 60 degree, 72 hours after-filtration are soaked in sealing then, and filtrate is concentrated;
2. hot dipping: the previous step filtering residue continues to add the pure rice wine 5000ml of 60 degree, heating in water bath refluxed 2 hours, clock from boiling, so operation is twice, the merging of above-mentioned three times filtrate is concentrated into no ethanol, this concentrated solution is transferred in the 5000ml distilling apparatus, dilute from distillation and reflux device moving valve adding distilled water topmost to 2000ml, the reheat dissolving, placement is spent the night;
3. thermosol: previous step has solid and separates out after placing and spending the night, and filters, and filtrate is abandoned it, and filtering residue continues to add the 900ml hot water dissolving and places and spend the night;
4. purify and concentrate: after previous step is placed and spent the night, have solid to separate out, slowly filter, filtrate is abandoned it, the filtering residue adding distil water is to 1000ml, it is muddy until transparent nothings of solution that heating makes it dissolving, filtered while hot after the dissolving, and filtrate is transferred in the big stainless steel cask adding distil water to 2000ml, make it to keep liquid not seethe with excitement with the electric furnace heating, place then and spend the night, repeat aforesaid operations three times, soon concentrated solution places Rotary Evaporators to be concentrated into 1000ml and gets semi-finished product;
5. dry: 50 ℃ of about finished products that got final product in a day of oven dry, stand-by.
7. the preparation method of the described function of invigorating circulation and reducing blood fat medicine of claim 5 is characterized in that the extracting method of described glossy ganoderma ointment is as follows:
1. merceration: get Ganoderma 1Kg, next step after the rice wine 3000ml sealing that then broken end is added 50 degree is soaked 72 hours, is continued in broken end;
2. hot dipping: again with rice wine 2000ml, heating in water bath refluxed 2 hours with the Ganoderma soak, clocked from boiling, so operated twice, and the merging of above-mentioned three times filtrate is concentrated into no ethanol, places Rotary Evaporators to be concentrated into 1000ml last concentrated solution again;
3. dry: 50 ℃ of oven dry got final product in one day finished product, stand-by.
8. a lipid-lowering and healthcare liquor is characterized in that containing in every 100ml rice wine the described medicine of 20g claim 1-3.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008102196660A CN101428117A (en) | 2008-12-04 | 2008-12-04 | Medicament for invigorating pulse and reducing adipose, and preparation method thereof |
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| CNA2008102196660A CN101428117A (en) | 2008-12-04 | 2008-12-04 | Medicament for invigorating pulse and reducing adipose, and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102138947A (en) * | 2011-03-28 | 2011-08-03 | 浙江省中医药研究院 | Propolis Chinese medicinal composition |
| CN103622027A (en) * | 2013-12-18 | 2014-03-12 | 绿之韵生物工程集团有限公司 | Health-care food composition for reducing blood glucose |
| CN104957624A (en) * | 2015-07-21 | 2015-10-07 | 熊玉雪 | Plant formula health product for human body |
| CN105267283A (en) * | 2014-07-02 | 2016-01-27 | 湖南绅泰春药业有限公司 | Pharmaceutical composition with efficacy of reducing blood fat and preparation method of pharmaceutical composition |
| CN105876029A (en) * | 2016-06-11 | 2016-08-24 | 邵则信 | Dendrobium candidum compound beverage and preparing method thereof |
| CN106754154A (en) * | 2017-02-17 | 2017-05-31 | 重庆葛根文化传播有限公司 | Mulberry health care wine and preparation method thereof |
-
2008
- 2008-12-04 CN CNA2008102196660A patent/CN101428117A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102138947A (en) * | 2011-03-28 | 2011-08-03 | 浙江省中医药研究院 | Propolis Chinese medicinal composition |
| CN103622027A (en) * | 2013-12-18 | 2014-03-12 | 绿之韵生物工程集团有限公司 | Health-care food composition for reducing blood glucose |
| CN103622027B (en) * | 2013-12-18 | 2016-01-27 | 绿之韵生物工程集团有限公司 | A kind of hypoglycemia healthcare food composition |
| CN105267283A (en) * | 2014-07-02 | 2016-01-27 | 湖南绅泰春药业有限公司 | Pharmaceutical composition with efficacy of reducing blood fat and preparation method of pharmaceutical composition |
| CN105267283B (en) * | 2014-07-02 | 2020-11-27 | 湖南绅泰春药业有限公司 | Pharmaceutical composition for reducing blood fat and preparation method thereof |
| CN104957624A (en) * | 2015-07-21 | 2015-10-07 | 熊玉雪 | Plant formula health product for human body |
| CN105876029A (en) * | 2016-06-11 | 2016-08-24 | 邵则信 | Dendrobium candidum compound beverage and preparing method thereof |
| CN106754154A (en) * | 2017-02-17 | 2017-05-31 | 重庆葛根文化传播有限公司 | Mulberry health care wine and preparation method thereof |
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Open date: 20090513 |