CN101406583A

CN101406583A - Externally applied Chinese medicine ointment for treating pyogenic skin infection caused by skin traumatism

Info

Publication number: CN101406583A
Application number: CNA2008101591925A
Authority: CN
Inventors: 邹连琦; 邹峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-11-28
Filing date: 2008-11-28
Publication date: 2009-04-15
Anticipated expiration: 2028-11-28
Also published as: CN101406583B

Abstract

The invention discloses an external traditional Chinese medicinal ointment for treating pyogenic skin infections caused by skin traumas. The external traditional Chinese medicinal ointment consists of the following traditional Chinese medicine in weight percentages: 4 to 6 percent of angelica dahurica, 6 to 8 percent of lithospermum, 60 to 80 percent of angelica, 6 to 8 percent of liquorice, 4 to 6 percent of phellodendron, 4 to 5 percent of dragon blood, and 1 to 2 percent of saffron. The external traditional Chinese medicinal ointment for treating the pyogenic skin infections caused by the skin traumas not only has good efficacies on the treatment of general pyogenic skin infections, but also has better efficacies particularly on pyogenic skin infections caused by traumas and pyogenic skin infections caused by slow healing of incisions, and has the advantages of short treatment time, high cure rate, and convenient use.

Description

A kind of Traditional Chinese Medicine for external application ointment for the treatment of pyogenic skin infection caused by skin traumatism

Technical field

The present invention relates to a kind of Chinese medicine preparation, especially a kind of Traditional Chinese Medicine for external application ointment for the treatment of pyogenic skin infection caused by skin traumatism.

Background technology

Skin infection is meant the body surface purulent disease that causes behind certain paathogenic factor invasion and attack human body.Skin infection is divided into multiple, and the most common in surgery with the skin infection due to skin infection due to the wound and the edge of a knife disunion of operation back, therefore, the present invention stresses to treat this type of skin infection.Skin infection due to skin infection due to the wound and the edge of a knife disunion of operation back often causes disorganization and necrosis, makes wound be difficult to healing, thereby forms the physiological obstacle, and general place is darker, and severe patient festers and can reach muscles and bones deeply.Clinical symptoms is: wound surface suppurates or purulent exudate is arranged; Edge of a knife suppuration disunion or foul smelling; Skin rubefaction or purple on every side dead color soak swollenly around the wound face, occur that wound surface caves in or meat turns up; The patient is with pain heating or low grade fever Mental fatigue, bitter taste and do, fatigue and weak, poor appetite lack of appetite; Pale tongue, tongue are few, deep-thready pulse etc.Its pathogeny, doctor trained in Western medicine is thought: this disease is to invade wound surface mixed infection by one or more malignant bacterias to cause, as staphylococcus aureus, streptococcus and escherichia coli etc., thereby causes red, swollen, suppuration.The traditional Chinese medical science is thought: body surface wound or knife injury must blood trouble network blood vessels, so that stop up the blood vessels that stagnate, coagulation of QI-blood, blocking barrier, strongly fragrant and heat-transformation, the corruption of heat stagnation meat, meat corruption pus.At present, the method for the treatment of such skin infection has multiple, and doctor trained in Western medicine method commonly used is mainly Drug therapy and operative treatment, Drug therapy is that the external application of tincture gauze is decided with 0.5% hibitane in the part, and intravenous injection, though effective in cure, but local irritation is big, and curative effect is not good enough, and the course of treatment is long; Operative treatment is the surgery skin grafting method, the surgery skin grafting method mainly is applicable to the skin infection that wound is more shallow, the skin infection darker to wound then is not suitable for, because middle pachydermia has certain nerve, often cause wound surface once not cover, and then residual wound surface need the second operation reparation, strengthened the wound of operation, prolonged operating time and treatment time, simultaneously, the patient suffering is big, surgery cost is high.At present, adopt the unguentum of treatment by Chinese herbs more, mainly contain golden yellow cream, YULU cream, TAIYI GAO, Rhizoma Coptidis cream, YUSHIZHI RUANGAO etc., mostly based on heat-clearing and toxic substances removing, be equipped with promoting flow of QI and blood, putrefaction removing evacuation of pus or promoting tissue regeneration and wound healing medicine, these unguentum are applied to the affected part, though certain curative effect is arranged, but treatment time is long, cure rate is lower, particularly for the skin infection due to skin infection due to the wound and slow outer infection of operation back wound healing, so class skin infection general position is darker, so curative effect is poorer.

Summary of the invention

The object of the present invention is to provide a kind ofly not only has better therapeutic effect to general skin infection, and a kind of Traditional Chinese Medicine for external application ointment for the treatment of pyogenic skin infection caused by skin traumatism of better therapeutic effect is particularly arranged for skin infection due to skin infection due to the wound and the edge of a knife disunion of operation back.

For reaching above purpose, the technical solution adopted in the present invention is: this a kind of Traditional Chinese Medicine for external application ointment for the treatment of pyogenic skin infection caused by skin traumatism is characterized in that being made up of the raw material of Chinese medicine of following percentage by weight: Radix Angelicae Dahuricae 4-6%, Radix Arnebiae (Radix Lithospermi) 6-8%, Radix Angelicae Sinensis 60-80%, Radix Glycyrrhizae 6-8%, Cortex Phellodendri 4-6%, Sanguis Draxonis 4-5%, Stigma Croci 1-2%.

Described a kind of Traditional Chinese Medicine for external application ointment for the treatment of pyogenic skin infection caused by skin traumatism is characterized in that being finished by following steps: one, take by weighing earlier Radix Angelicae Dahuricae 4-6%, Radix Arnebiae (Radix Lithospermi) 6-8%, Radix Angelicae Sinensis 60-80%, Radix Glycyrrhizae 6-8%, Cortex Phellodendri 4-6%, Sanguis Draxonis 4-5%, Stigma Croci 1-2% in proportion; Two, again the Radix Angelicae Dahuricae, Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Radix Glycyrrhizae, Cortex Phellodendri, the Stigma Croci that takes by weighing mixed, putting into the container that fills Oleum sesami flooded 24 hours, the amount of putting into of Oleum sesami did not get final product there not to be hybrid medicine, make the oil immersion hybrid medicine, again the Sanguis Draxonis that takes by weighing is pulverized, cross the 100-120 mesh sieve, be made for fine powder of dragons blood, leave in the container standby; Three, with the fried system of oil immersion hybrid medicine slow fire, fried stopping when the Radix Angelicae Dahuricae presents sepia heated, and filter and remove residue adds Cera Flava and melts, put into medicine container after refiltering, add fine powder of dragons blood again, be stirred into ointment and put into the ointment container, the ointment container that holds ointment is put into cold water again cool off releasing fire-toxin, after cooling to room temperature, pack into to add a cover in the flexible plastic medicine bottle and seal up for safekeeping, every bottle of 20g promptly becomes the Traditional Chinese Medicine for external application ointment finished product of treatment pyogenic skin infection caused by skin traumatism.

Described a kind of using method for the treatment of the Traditional Chinese Medicine for external application ointment of pyogenic skin infection caused by skin traumatism:

Before the medication, to wipe out the skin ulcer face with the cutter of the poison that disappeared and dislike meat, alternately wound surface is washed 2-3 time with hydrogen peroxide and normal saline, and then the Traditional Chinese Medicine for external application ointment that will treat pyogenic skin infection caused by skin traumatism is applied to the skin ulcer face, wrap up with gauze, repeat flushing every day, change dressings once, treat that purulent secretion reduces after, every other day repeat flushing and change dressings once.14 days is a course of treatment.Avoid eating anything raw or cold during the medication, delicious food savoury and spicy food, avoid tobacco and wine.Pathological changes is the careful usefulness of person near eye, lip, all unknown causes fever, weak, mouthful in the drug withdrawal immediately of symptoms such as metallic taste is arranged.

From 2003-2007, the 600 routine skin infection patients that have in the undergraduate course treatment adopt this traditional Chinese herb medicine external application for curing, and the treatment through 1-2 month has all obtained good result, wherein cures 558 examples, cure rate 93%; 42 examples that take a turn for the better, improvement rate 7%.

Beneficial effect of the present invention is: compare with the employed Chinese medicine lotion for external use agent of present treatment skin infection, not only better to treating general skin infection curative effect, especially to skin infection due to the wound and wound healing slowly due to skin infection better therapeutic effect is arranged, treatment time is short, the cure rate height, easy to use.

Pharmacology of the present invention is:

The Radix Angelicae Dahuricae: belong to refrigerant diaphoretic medicine, acrid in the mouth, warm in nature attaches to the lung and stomach meridians, and has the poison of dispeling the wind, diffusing stagnated fire, broken stagnated blood, changes the effect that loses evacuation of pus, pain relieving;

Radix Arnebiae (Radix Lithospermi): belong to heat and toxic materials clearing away medicine, sweet in the mouth, cold in nature, GUIXIN, Liver Channel, the tool removing pathogenic heat from blood and toxic substance from the body has the effect of putrefaction removing detumescence;

Radix Angelicae Sinensis: the genus limonium medicine, sweet in the mouth, warm in nature, return liver, the heart, spleen channel, have that dissipating blood stasis capablely stagnates, the effect of nourshing blood and promoting blood circulation;

Radix Glycyrrhizae: belong to qi-restoratives medicine, acrid in the mouth, GUIXIN warm in nature, liver, spleen channel, have enrich blood, the effect of promoting blood circulation and stopping pain, the mitigation property of medicine;

Cortex Phellodendri: belong to heat clearing and dampness removing medicine, bitter in the mouth, cold in nature, GUIXIN, liver, stomach, large intestine channel have heat clearing and damp drying, unload the effect of fire detoxifcation;

Sanguis Draxonis: belong to medicine for external use, have the effect of dissipating blood stasis analgesic therapy, putrefaction-removing granulation-promoting, arresting bleeding and healing up ulcer;

Stigma Croci: belong to the activating blood and removing stasis medicine, acrid in the mouth, warm in nature, GUIXIN, Liver Channel have that activating blood and removing stasis stimulates the menstrual flow, active effect.All medicines share, focus on that dissipating blood stasis capablely stagnates, nourshing blood and promoting blood circulation is enriched blood, heat-clearing and toxic substances removing, be aided with putrefaction removing evacuation of pus, granulation promoting, actively stimulate the menstrual flow, arresting bleeding and healing up ulcer, not only act on the top layer, more can act on deep layer, so the deep layer skin infection that traumatic and operative incision are caused has better therapeutic.

Analysis of clinical

One, diagnostic criteria

According to " disease of tcm and diagnosis and treatment standard and prescription are selected (the sick diagnostic criteria of decubital ulcer) for use " that People's Health Publisher calendar year 2001 publishes, injure outward do not heal after the operation due to the skin infection symptom: wound surface suppuration or exudate is arranged or have purulent exudate to ooze out; Operation back incision infection suppurates; Wound surface or the rubescent or atropurpureus of edge of a knife surrounding skin; Meat turns up or caves in, organize rapid necrosis to fester during little swollen, secondary contamination, and pus is dripping; Pain or foul smelling, weight person is festered, and can reach muscles and bones deeply; And with refreshing dispirited, the eye difference dreaminess of heating or low grade fever, weak, type, the not good enough symptom of diet; Greasy fur on tongue and Huang, rolling pulse, number, or coating nature is light, white and thin fur, deep pulse, thin, number.

Two, criterion of therapeutical effect

" disease of tcm and diagnosis and treatment standard and prescription are selected (the sick diagnostic criteria of decubital ulcer) for use " according to People's Health Publisher's calendar year 2001 publication:

Cure: the skin ulcer face does not have exudate, the purple dead color of the scar mouth color that reddens, and wound healing festers;

Take a turn for the better: skin ulcer face exudate reduces, kermesinus, and the skin ulcer face dwindles gradually, granulation;

Do not heal: the open sore part is not seen obvious change.

Three, efficacy result analysis

From 2003-2007, that comes the treatment of my section makes a definite diagnosis 600 routine skin infection patients altogether, judges curative effect two courses of treatment through treating.By above standard, determine to cure patient's 558 examples altogether, cure rate 93%, less than healing person's two courses of treatment 478 examples wherein, two 112 examples of curing the course of treatment, two the course of treatment above 10 examples of curing; 42 examples that take a turn for the better, improvement rate 7%.Tracing study 2 years is not seen recurrence or is caused the physiological barrier case in the 558 routine cases of healing.

Specific embodiment

Embodiment 1

Ratio in the Radix Angelicae Dahuricae 5%, Radix Arnebiae (Radix Lithospermi) 7%, Radix Angelicae Sinensis 70%, Radix Glycyrrhizae 7%, Cortex Phellodendri 5%, Sanguis Draxonis 4.5%, Stigma Croci 1.5% takes by weighing each medicine material, after taking by weighing, the Radix Angelicae Dahuricae, Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Radix Glycyrrhizae, Cortex Phellodendri, Stigma Croci were put into 450ml Oleum sesami dipping 24 hours, make the oil immersion hybrid medicine, the Sanguis Draxonis that takes by weighing is pulverized, it is stand-by that mistake 120 mesh sieves are made fine powder of dragons blood again; With the fried system of oil immersion hybrid medicine slow fire, fried when the Radix Angelicae Dahuricae presents sepia, add Cera Flava and dissolve, put into medicine container after refiltering, add fine powder of dragons blood again, be stirred into paste, put into the ointment container, the container that will contain ointment is again put into cold water and is reduced internal heat and draw out pus by applying a plaster to the affected part, after cooling to room temperature, pack into to add a cover in the flexible plastic medicine bottle and seal up for safekeeping, every bottle of 20g promptly becomes this traditional Chinese herb medicine finished product.

With skin infection due to this Traditional Chinese Medicine for external application Ointment in Treatment wound and operation back wound healing slow due to skin infection patient 200 examples, the normal developing wound surface is 2-3 time before the treatment, is applied to the affected part then, with the gauze wrapping, change dressings every day once, cure 190 examples in one month, cure rate 95%, 10 examples that take a turn for the better, improvement rate 5%.

Model case: Li Jinyu, woman, Cao Sheng people from village, Niu Quan town, 6 years old Laiwu City Laicheng district, because of the bicycle quick extruding causes right calcaneus place wound, about 3 * 4 centimetres of wound surface is deep to periosteum, come me section to go to a doctor, wound surface surrounding skin puce during prescription on individual diagnosis, the wound surface purulent exudate is more, pain, heating, light red tongue, the little Huang of tongue, rapid pulse.Behind the cleaning of the debridement way routinely wound surface, this traditional Chinese herb medicine scumbling in wound surface, is changed dressings once every day, medication is after five days, and purulent secretion reduced, and changed one time medicine every one day, with this traditional Chinese herb medicine treatment recovery from illness in 28 days.

Embodiment 2

Ratio in the Radix Angelicae Dahuricae 4%, Radix Arnebiae (Radix Lithospermi) 8%, Radix Angelicae Sinensis 70%, Radix Glycyrrhizae 8%, Cortex Phellodendri 4%, Stigma Croci 2%, Sanguis Draxonis 4% takes by weighing each medicine material.Manufacture method is with embodiment 1.With change due to this Traditional Chinese Medicine for external application Ointment in Treatment wound skin infection with operation back wound healing slow due to skin infection patient 200 examples.Therapeutic Method is with embodiment 1.Treat two courses of treatment, cure 182 examples, cure rate 91%, 18 examples that take a turn for the better, improvement rate 9%.

Model case: Lu is engaged in male forever, and 43 years old, Zhang Jiawa town, Laiwu City Laicheng district Jia Jia people from village.The careless electric fan wing left leg of injuring in the workshop, about 3 * 10 centimetres of wound surface area, the CT examination sclerotin is normal, through the doctor trained in Western medicine treatment of wounds, use antibiotics not take effect in a large number, I went to a doctor at section afterwards, symptom: the open sore part is festered, purulent exudate is more, festers to reach muscles and bones deeply, soaks swollen all around, kermesinus, with low grade fever, body and the spirit is dispirited, anorexia etc.; Red tongue, tongue is few, thready and rapid pulse.After clearing up wound routinely, with this traditional Chinese herb medicine treatment recovery from illness in 30 days.

Embodiment 3

Ratio in the Radix Angelicae Dahuricae 5%, Radix Arnebiae (Radix Lithospermi) 5%, Radix Angelicae Sinensis 71%, Radix Glycyrrhizae 7%, Cortex Phellodendri 6%, Stigma Croci 1%, Sanguis Draxonis 5% takes by weighing each medicine material.Manufacture method is with embodiment 1.With suppuration skin infection due to this traditional Chinese herb medicine treatment wound and operation back wound healing slow due to skin infection patient 200 examples, the coating method is cured 186 examples with embodiment 1, two course of treatment, cure rate 93%, 14 examples that take a turn for the better, improvement rate 7%.

Model case: Bears is according to brightness man, 26 years old, the staff of the Laiwu City institute of agricultural sciences.The nearly clavicle of right side cervical region place lymph node excises because of enlargement, and biopsy is shown: the tuberculosis tuberculous lymphadenitis.The long-time disunion of the edge of a knife is also suppurated through drain, cleans, and external YUSHIZHI RUANGAO therapeutic effect is not good enough, coming, I go to a doctor about 3 * 5 centimetres of skin ulcer face, about deeply 1-2 centimetre at section, purulent secretion is more, and peripheral skin is dark red, and skin ulcer face slough difficulty is taken off, new flesh color is light, soak all around swollen scorching hot, with eczema, do during sufferings, the time low grade fever is arranged, spiritlessness and weakness, poor appetite lack of appetite etc.Body of the tongue is light red, and tongue is few, and deep pulse is counted accurately.Use this traditional Chinese herb medicine, change dressings every day once, medication is after 5 days, and purulent secretion obviously reduces, and every other day changes medicine one time, and after the medication 10, the skin ulcer reduction of area causes 3 * 2 centimetres, about deeply 1-1.5 centimetre, uses this cream; Treat recovery from illness on the 20th.

Claims

1, a kind of Traditional Chinese Medicine for external application ointment for the treatment of pyogenic skin infection caused by skin traumatism is characterized in that being made up of the raw material of Chinese medicine of following percentage by weight: Radix Angelicae Dahuricae 4-6%, Radix Arnebiae (Radix Lithospermi) 6-8%, Radix Angelicae Sinensis 60-80%, Radix Glycyrrhizae 6-8%, Cortex Phellodendri 4-6%, Sanguis Draxonis 4-5%, Stigma Croci 1-2%.

2, a kind of Traditional Chinese Medicine for external application ointment for the treatment of pyogenic skin infection caused by skin traumatism according to claim 1 is characterized in that being finished by following steps: one, take by weighing earlier Radix Angelicae Dahuricae 4-6%, Radix Arnebiae (Radix Lithospermi) 6-8%, Radix Angelicae Sinensis 60-80%, Radix Glycyrrhizae 6-8%, Cortex Phellodendri 4-6%, Sanguis Draxonis 4-5%, Stigma Croci 1-2% in proportion; Two, again the Radix Angelicae Dahuricae, Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Radix Glycyrrhizae, Cortex Phellodendri, the Stigma Croci that takes by weighing mixed, put into the container that fills Oleum sesami and flooded 24 hours, make the oil immersion hybrid medicine, again the Sanguis Draxonis that takes by weighing is pulverized, cross the 100-120 mesh sieve, be made for fine powder of dragons blood, leave in the container standby; Three, with the fried system of oil immersion hybrid medicine slow fire, fried stopping when the Radix Angelicae Dahuricae presents sepia heated, and filter and remove residue adds Cera Flava and melts, put into medicine container after refiltering, add fine powder of dragons blood again, be stirred into ointment and put into the ointment container, the ointment container that holds ointment is put into cold water again cool off releasing fire-toxin, after cooling to room temperature, pack into to add a cover in the flexible plastic medicine bottle and seal up for safekeeping, every bottle of 20g promptly becomes the Traditional Chinese Medicine for external application ointment finished product of treatment pyogenic skin infection caused by skin traumatism.