CN101406196B - Mite-killing composition containing active substance of tetronic acid - Google Patents
Mite-killing composition containing active substance of tetronic acid Download PDFInfo
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- CN101406196B CN101406196B CN2008101819749A CN200810181974A CN101406196B CN 101406196 B CN101406196 B CN 101406196B CN 2008101819749 A CN2008101819749 A CN 2008101819749A CN 200810181974 A CN200810181974 A CN 200810181974A CN 101406196 B CN101406196 B CN 101406196B
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- macro tetrolide
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Abstract
The invention relates to an acaricide composition containing tetronic acid active substances. The active ingredients of the acaricide composition are spirodiclofen (A) and liuyangmycin (B), the mass ratio of A to B is between 10 to 1 and 1 to 10; and according to the prior method, the original drug containing the active ingredients and auxiliary materials are processed together to be prepared into any dosage form suitable for agricultural application, wherein the better dosage forms comprise emulsifiable solution, suspending agents, water emulsion, water dispersible granules and the like, andthe total content of the active ingredients in the preparation is between 5 and 80 percent. The acaricide composition has obvious synergism on controlling pest mites on crops, has good quick effect and long duration, and is helpful to delay the drug resistance generation of the pest mites; and the acaricide composition is mainly used for controlling the pest mites on the crops such as fruit trees, cottons, and vegetables.
Description
Technical field
The present invention relates to a kind of composition pesticide and uses thereof, specifically is to be the miticide composition of active ingredient with spiral shell mite ester and macro tetrolide, is used to prevent and treat the mite pest on the agricultural, especially is suitable for preventing and treating the tetranychid of fruit tree, vegetables, flowers.
Technical background
Spiral shell mite ester has another name called spirodiclofen, and English general Spirodiclofen by name belongs to novel tetronic acid class miticide.Mechanism of action is for destroying the energy metabolism activity of acarid by the lipogenesis in the inhibition evil mite body.It is distinguished to mite ovum effect, if mite also has good contact toxicity, but to the female one-tenth mite poor effect of tagging, can not control harm rapidly when the big generation of evil mite to the children.It is a kind of efficient non-internal-absorting leaf surface treatment miticide, does not have the cross resistance problem with other existing miticide, is particularly suitable for preventing and treating the pest mite class that existing miticide is produced resistance.
Macro tetrolide, English general Liuyangmycin by name is a kind of mite antibiotic extremely with macrolide structure that is produced by the mutation of streptomyces griseus Liuyang.This medicine low toxicity, low-residual can be prevented and treated the multiple mite class of various crop, and control efficiency is good, to natural enemies security, does not have cross resistance with conventional pesticide.
The above-mentioned mite class of mentioning has another name called two spotted spider mite, white spider etc., belongs to the Arthropoda arachnids.The mite class of crop of mainly causing harm on agricultural mainly contains tetranychid and goitre mite, rust mites etc. such as Panonychus citri, Tetranychus cinnabarinus, Tetranychus urticae.The mite class of these crops of causing harm has usually that egg laying amount is big, and reproduction speed is fast, and population density is big, and generation overlap is obvious, and characteristics such as easily develop immunity to drugs.Usually cause fruit to spend skin, leaf chlorosis distortion, fruit tree nutrition is bad, occurs fallen flowers at last, falls leaves, falls destructive consequence such as fruit.
In the real process of China's agricultural production, chemical control is the main effective means of control mite class.The problem that the chemical control insect is easy to generate most is the generation of pest resistance to insecticide.The mite class easily develops immunity to drugs, panonychus citri especially, and under the condition of long-term single drug, resistance produces very fast.The independent uses of medicament such as main control mite class medicament such as pyridaben, azacyclotin, Hexythiazox, four mite piperazines usually can not be controlled the harm of mite class effectively.
Go up the mite pest that produces resistance for control agricultural, a kind of way is to release the new component that new and existing kind do not have cross resistance.But, the development cost height of new active ingredient, the construction cycle is long, and all produces the speed of resistance forever less than insect.Other method such as crop allocation adjustment, biological control etc. in the process of practical operation, are difficult to really play obvious effects.
In China, stronger to acaricidal dependences of import such as spiral shell mite esters at present, be difficult to obtain, and cost an arm and a leg, use to be confined to partly developed area more, can not be used by all have the peasant in the area that needs; Because resistance problem, other cheap miticide effect commonly used is poor again.Therefore, control efficiency is good, and low toxicity, low-residual, the relatively low miticide of use cost are especially orchard worker, vegetable grower, flower-grower's etc. active demands of vast farmers.
Summary of the invention
The purpose of this invention is to provide a kind of miticide composition, it is to the control efficiency excellence of evil mite, and quick-acting is good and the lasting period is long, the usage amount that can reduce agricultural chemicals with help to overcome and delay to do harm to the mite pesticide resistance.
The present invention has found that by a large amount of biologicall test screenings spiral shell mite ester and macro tetrolide are composite with certain proportion, and mite pests such as antagonism property of medicine Panonychus citri, Tetranychus urticae have remarkable synergistic effect.The active ingredient of the present composition is spiral shell mite ester (A) and macro tetrolide (B), the mass ratio of A and B is between 10:1-1:10, the former medicine that will contain active ingredient by present known method is processed into any formulation that suitable agricultural is upward used with auxiliary material, formulation comprises missible oil, suspending agent, aqueous emulsion, water dispersible granules etc. preferably, and the total content of active ingredient is 5-80% in the preparation.
Auxiliary material in the present composition comprises that solvent, dispersant, wetting agent, emulsifier, stabilizing agent, thickener, pH regulator agent, antifreezing agent, excipient, filler and other are of value to the known substance of active ingredient stable and drug effect performance in preparation, all be the various compositions that permission commonly used in the pesticidal preparations is used, be not particularly limited.
In view of single medicament is difficult to satisfy the mite class control needs that agricultural goes up serious harm, in order to seek to prevent and treat the desirable medicament of harmful mite, the inventor has carried out mutual composite synergy research with compositions such as spiral shell mite ester, macro tetrolides.It is tested object that Panonychus citri, Tetranychus cinnabarinus are adopted in test, and concrete grammar is:
1) panonychus citri (Panonychus citri)
The examination worm is the panonychus citri that picks up from the field, indoor oranges and tangerines seedling is raised, select the consistent female one-tenth mite of growth for examination. the leaf dish spray-on process in " People's Republic of China's agricultural industry criteria one agricultural chemicals indoor bioassay test rule " is adopted in test, blank spray equivalent clear water.The result carries out statistical analysis with the DPS data processing software, calculates the LC50 of each medicament, estimates the activity of reagent agent to the examination worm with this.
The co-toxicity coefficient of mixture (CTC value) calculates by following formula:
In the formula:
ATI---mixture actual measurement toxicity index;
The LC of S---standard insecticide
50, unit is every liter (mg/l) of milligram;
The LC of M---mixture
50, unit is every liter (mg/l) of milligram;
TTI＝TI
AxP
A+TI
BxP
B
In the formula:
The theoretical toxicity index of TTI---mixture;
TI
A----A medicament toxicity index;
P
AThe percentage composition of-----A medicament in mixture, unit is a percentage;
TI
B----B medicament toxicity index;
P
BThe percentage composition of-----B medicament in mixture, unit is a percentage.
In the formula:
The CTC----co-toxicity coefficient;
ATI---mixture actual measurement toxicity index;
The theoretical toxicity index of TTI---mixture.
Composite dose co-toxicity coefficient (CTC) 〉=120 shows as synergistic effect; CTC≤80 show as antagonism; 80＜CTC＜120 show as summation action.
2) Tetranychus urticae (Tetranychus urticae Koah)
Test method is with reference to " the agricultural industry criteria NY/T1154.7-2006 of the People's Republic of China (PRC) ".The examination worm is the Tetranychus urticae that picks up from the field, and warm indoor strawberry seedling is raised, and it is consistent to select growth, the strawberry seedling that has even Tetranychus urticae to take place, and every processing connects 16 basins, and per 4 basins are a repetition, investigation radix before every basin medicine.With cover compression sprayer 0.02 liter of spray liquor under 5PSI pressure, sedimentation 3 minutes are arranged; Each processing is provided with 5 concentration gradients, blank spray equivalent clear water.The strawberry seedling of handling is put into booth cultivate, the borer population of check living after 7 days calculates the insect population rate that goes down.Carry out statistical analysis with the DPS data processing software, calculate the LC of each medicament
50, estimate the activity of reagent agent to the examination worm with this.
3) measurement result: to the toxicity test result of Panonychus citri and Tetranychus urticae see Table 1 respectively, table 2.
Table 1 different disposal is to the toxicity test result of Panonychus citri
| Handle | LC 50(mg/L) | ATI | TTI | CTC |
| Spiral shell mite ester (A) | 40.23 | 100.00 | ||
| Macro tetrolide (B) | 18.96 | 212.18 | ||
| (A)10+(B)1 | 15.43 | 260.73 | 105.34 | 247.50 |
| (A)7+(B)1 | 13.11 | 306.86 | 110.20 | 278.47 |
| (A)4+(B)1 | 11.54 | 348.61 | 118.70 | 293.70 |
| (A)1+(B)1 | 8.65 | 465.09 | 156.09 | 297.96 |
| (A)1+(B)4 | 9.08 | 443.06 | 193.49 | 228.99 |
| (A)1+(B)7 | 9.64 | 417.32 | 201.99 | 206.61 |
| (A)1+(B)10 | 8.93 | 450.50 | 206.84 | 217.80 |
Table 2 different disposal is to the toxicity test result of Tetranychus urticae
| Handle | LC 50(mg/L) | ATI | TTI | CTC |
| Spiral shell mite ester (A) | 30.21 | 100.00 | ||
| Macro tetrolide (B) | 12.8 | 236.02 | ||
| (A)10+(B)1 | 8.94 | 337.92 | 112.37 | 300.73 |
| (A)5+(B)1 | 8.24 | 366.63 | 122.67 | 298.87 |
| (A)1+(B)1 | 8.64 | 349.65 | 168.01 | 208.12 |
| (A)1+(B)5 | 6.52 | 463.34 | 213.35 | 217.18 |
| (A)1+(B)10 | 6.13 | 492.82 | 223.65 | 220.35 |
As seen from Table 1, spiral shell mite ester and macro tetrolide are composite, and Panonychus citri is had very high synergistic effect.Co-toxicity coefficient can reach more than 200 when spiral shell mite ester and macro tetrolide proportioning were 10:1-1:10.
As seen from Table 2, spiral shell mite ester and macro tetrolide are composite, the synergistic effect very high to Tetranychus urticae.Co-toxicity coefficient can reach more than 200 when spiral shell mite ester and macro tetrolide proportioning were 10:1-1:10.
Miticide composition of the present invention compared with prior art, beneficial effect is: (1) is compared with single agent, and said composition has tangible synergy to the mite class, has improved control efficiency; (2) can significantly reduce the field dosage, effectively reduce environmental pollution and residue of pesticide, reduce harm beneficial organism; (3) compare with the agent of spiral shell mite ester list, better quick-acting is arranged, produce and the use cost reduction; (4) compare with the agent of macro tetrolide list, longer lasting effect is arranged, more remarkable effect; (5) suppress the mite class to the drug-fast enhancing of agricultural chemicals.
Embodiment
In order to make purpose of the present invention, technical scheme and advantage clearer, summary of the invention is described in further detail below in conjunction with embodiment.Should be appreciated that specific embodiment described herein only in order to explanation the present invention, and be not used in qualification the present invention.
Percentage all is weight percentage in the proportioning of all preparations.The treatment dosage of the biologicall test part and the test of pesticide effectiveness is effective content.
Embodiment 1:20% spiral shell mite ester macro tetrolide missible oil
Spiral shell mite ester 10%
Macro tetrolide 10%
Calcium dodecyl benzene sulfonate 4%
Triphenylethylene base APEO 3%
N-Methyl pyrrolidone 10%
Dimethylbenzene to 100%
Active component, emulsifier and the auxiliary agent ratio in prescription is added in the mixing kettle successively, stir, make 20% spiral shell mite ester macro tetrolide missible oil.
This embodiment is applied to prevent and treat the Panonychus citri on the oranges and tangerines.20% spiral shell mite ester macro tetrolide missible oil is diluted even spraying for 3000 times to water, 1 day preventive effect is 88.7% behind the medicine, 24% 5000 times of spiral shell mite ester suspending agents and 10% macro tetrolide missible oil are by 1000 times, with using with quadrat method, 1 day preventive effect is respectively 59.6% and 85.2% behind the medicine, the quick-acting spiral shell mite esters that significantly are better than; 15 days control efficiency are 97.6%, 24% spiral shell mite ester suspending agent by 5000 times and 10% macro tetrolide missible oil by 1000 times behind the medicine, use with the quadrat method use, and 15 days preventive effects are respectively 90.6% and 78.8% behind the medicine.
This embodiment is applied to prevent and treat the Tetranychus urticae on the strawberry.20% spiral shell mite ester macro tetrolide missible oil is pressed 3000 extraordinarily water dilution sprayings, 30 days control efficiency are 96.3% behind the medicine, 24% spiral shell mite ester suspending agent is pressed 1000 times by 5000 times and 10% macro tetrolide missible oil, with using with quadrat method, preventive effect is respectively 93.1% and 58.3%, it is slightly excellent or suitable with spiral shell mite ester to hold effect, significantly is better than macro tetrolide.
Embodiment 2:27% spiral shell mite ester macro tetrolide suspending agent
Spiral shell mite ester 24%
Macro tetrolide 3%
Alkylaryl polyoxyethylene polyoxypropylene ether 8%
Poly-naphthaldehyde sulfonate sodium 2%
Glycerine 3%
Aluminium-magnesium silicate 1%
Water to 100%
By the prescription requirement, the former medicine pulverized in advance and carrier, surfactant, thickener, stabilizing agent, antifreezing agent, water etc. are added in the sand milling still, porphyrize mixes through high speed shear again, adjusts pH to 4 with acetic acid at last and makes 27% spiral shell mite ester macro tetrolide suspending agent.
This embodiment is applied to prevent and treat the Panonychus citri on the sweet orange.27% spiral shell mite ester macro tetrolide suspending agent is pressed 5000 extraordinarily water dilution sprayings, 15 days control efficiency are 98.2% behind the medicine, 24% spiral shell mite ester suspending agent is pressed 1000 times by 5000 times and 10% macro tetrolide missible oil, with using with quadrat method, 15 days preventive effects are respectively 84.3% and 79.4%, significant difference behind the medicine.
This embodiment is applied to prevent and treat the rust mite on the oranges and tangerines.27% spiral shell mite ester macro tetrolide suspending agent is pressed 6000 extraordinarily water dilution sprayings, 50 days control efficiency are 98.7% behind the medicine, 24% spiral shell mite ester suspending agent is pressed 1500 times by 6000 times and 10% macro tetrolide missible oil, with using with quadrat method, 50 days preventive effects are respectively 86.2% and 59.8%, significant difference behind the medicine.
Embodiment 3:60% spiral shell mite ester macro tetrolide water dispersible granules
Spiral shell mite ester 50%
Macro tetrolide 10%
Sodium lignin sulfonate 6%
Alkyl is sodium sulfonate 5% how
Lauryl sodium sulfate 2%
Ammonium sulfate 6%
Attapulgite to 100%
Active component, dispersant, wetting agent, disintegrant and the filler ratio in prescription is mixed, become wetting powder, add a certain amount of water mixing extruding again and make material, obtain 60% spiral shell mite ester macro tetrolide water dispersible granules after the drying screening through comminution by gas stream.
This embodiment is applied to prevent and treat the Tetranychus urticae on the tomato.This prescription is by 25000 extraordinarily water dilution sprayings, to be 93.2%, 24% spiral shell mite ester suspending agent press 1000 times by 5000 times and 10% macro tetrolide missible oil for 15 days control efficiency behind the medicine, uses with quadrat method and use, 15 days preventive effects are respectively 83.5% and 84.3%, significant difference behind the medicine.
This embodiment is applied to prevent and treat panonychus citri.This prescription is by 25000 extraordinarily water dilution sprayings, and 50 days control efficiency are 95.6%, 24% spiral shell mite ester suspending agent by 5000 times and 10% macro tetrolide missible oil by 1000 times behind the medicine, use with the quadrat method use, and preventive effect is respectively 83.3% and 46.2%, significant difference.
Embodiment 4:11% spiral shell mite ester macro tetrolide aqueous emulsion
Spiral shell mite ester 1%
Macro tetrolide 10%
Calcium dodecyl benzene sulfonate 4%
Styryl phenol APEO 5%
Xanthans 1%
Ethylene glycol 1%
Water to 100%
Former medicine, solvent, emulsifier are added together, make and be dissolved into even oil phase; With water-soluble component and the mixed water that gets of water; Under high-speed stirred, oil phase is mixed with water, make 11% spiral shell mite ester macro tetrolide aqueous emulsion.
This embodiment is applied to prevent and treat the Panonychus citri on the oranges and tangerines.This prescription is by 1500 extraordinarily water dilution sprayings, and 30 days control efficiency are 90.6%, 24% spiral shell mite ester suspending agent by 6000 times and 10% macro tetrolide missible oil by 1500 times behind the medicine, use with the quadrat method use, and preventive effect is respectively 81.2% and 76.3%, significant difference.
This embodiment is applied to prevent and treat the Tetranychus urticae on the strawberry.This prescription is by 1000 extraordinarily water dilution sprayings, to be 98.7%, 24% spiral shell mite ester suspending agent press 1000 times by 5000 times and 10% macro tetrolide missible oil for 15 days control efficiency behind the medicine, uses with quadrat method and use, 15 days preventive effects are respectively 94.3% and 83.1%, significant difference behind the medicine.
The above only is part of the present invention embodiment preferably, can not therefore be interpreted as the restriction to claim of the present invention.Should be pointed out that all any modifications of being made within the spirit and principles in the present invention, be equal to replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (4)
1. a miticide composition is characterized by and contains two kinds of active component spiral shell mite esters and macro tetrolide, and the ratio of quality and the number of copies of two kinds of active components is 10: 1-1: 10.
2. according to claim 1, it is characterized in that also containing normally used auxiliary element in the pesticidal preparations so that make the formulation that is fit to the agricultural use, the gross mass content of active ingredient is 5-80% in the preparation.
3. according to claim 2, it is characterized in that the formulation that is fit to is missible oil, suspending agent, aqueous emulsion, water-dispersible granules.
4. according to any one in the claim 1 to 3, it is characterized in that being used to prevent and treat the harmful mite of crop.
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| CN104273145B (en) * | 2014-10-15 | 2016-08-24 | 青岛青知企业管理咨询有限公司 | A kind of macro tetrolide and the compositions of d ichlorbenzuron and application |
| CN104322522B (en) * | 2014-10-15 | 2016-04-20 | 济南新起点医药科技有限公司 | A kind of water dispersible granules and application preventing and treating white-backed planthopper |
| CN104351240B (en) * | 2014-11-14 | 2016-08-24 | 青岛青知企业管理咨询有限公司 | A kind of composition containing cyfloxylate and application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1475115A (en) * | 2002-08-16 | 2004-02-18 | 张业生 | Pesticide for killing insect and acarid |
| WO2007083394A1 (en) * | 2006-01-19 | 2007-07-26 | Mitsui Chemicals, Inc. | Pest control composition containing diamine derivative |
-
2008
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1475115A (en) * | 2002-08-16 | 2004-02-18 | 张业生 | Pesticide for killing insect and acarid |
| WO2007083394A1 (en) * | 2006-01-19 | 2007-07-26 | Mitsui Chemicals, Inc. | Pest control composition containing diamine derivative |
Non-Patent Citations (7)
| Title |
|---|
| .24%螺螨酯悬浮剂防治柑桔全爪螨药效试验.《现代农药》.2007,第6卷(第5期),第49-50页. |
| 储春荣 |
| 储春荣;陈绍彬;张春晓;蔡健华;朱裕忠;.24%螺螨酯悬浮剂防治柑桔全爪螨药效试验.《现代农药》.2007,第6卷(第5期),第49-50页. * |
| 张春晓 |
| 朱裕忠 |
| 蔡健华 |
| 陈绍彬 |
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