CN101401915A - Chinese medicine formulation for treating cancer and preparation method thereof - Google Patents
Chinese medicine formulation for treating cancer and preparation method thereof Download PDFInfo
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- CN101401915A CN101401915A CNA2008102323045A CN200810232304A CN101401915A CN 101401915 A CN101401915 A CN 101401915A CN A2008102323045 A CNA2008102323045 A CN A2008102323045A CN 200810232304 A CN200810232304 A CN 200810232304A CN 101401915 A CN101401915 A CN 101401915A
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Abstract
The invention provides a Chinese medicine preparation for treating malignancy and a preparation method thereof. The preparation method comprises the following steps: firstly, pseudo-ginseng, Rhizoma Zedoariae, fritillariae thunbergii, Atractylodes macrocephala, edible tulip and Polyporus umbellate are dried and crushed into fine powder according to certain weight percent; secondly, Tephroseris kirilowii, Scutellaria barbata, Artemisia capillaries, radix astragali and liquorice with certain weight percent are added with water for decoction, a decoction solution is formed and filtered, and filtrate is decompressed and concentrated into condensed ointment; and thirdly, the fine powder and the condensed ointment are uniformly mixed, dried and crushed into fine powder which is then uniformly mixed and added with adequate water, so as to obtain the Chinese medicine preparation for treating the malignancy. The Chinese medicine preparation has obvious treatment effect on malignancy, particularly has obvious effects on preventing post-operation recurrence and metastasis and lightening the toxic side effect of chemicotherapy, is applicable to various cancer patients without untoward reaction and toxic side effect, relieves the symptoms and prolongs the life of the patients. The preparation method has simple technique, can improve the quality of the medicine and effectively improve the clinic treatment effect of the medicine.
Description
Technical field
The invention belongs to medical technical field, be specifically related to a kind of Chinese medicine preparation for the treatment of malignant tumor and preparation method thereof.
Background technology
Development along with medical skill, can be also more and more for the means of oncotherapy, such as the control of various palliative operations, local radiotherapy, gentleer chemotherapy, pain management, traditional Chinese medical herbal treatment, immunity and biological targeting treatment, various less invasive techniques, complication and advanced nursing monitoring technology or the like, but it is all similar aspect prescription, Therapeutic Method, effect, there is the problem of curing the symptoms, not the disease, especially exists problems such as easily recur the treatment back, toxic and side effects is big.In order to solve this difficult problem, people are constantly exploring and are studying.
Summary of the invention
Technical problem to be solved by this invention is at above-mentioned deficiency of the prior art, provide a kind of side effect little, adapt to that symptom is wide, treatment is convenient, cure the back is difficult for recurrence, continue to use, can cure tumor gradually, and the Chinese medicine preparation of treatment malignant tumor evident in efficacy.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine preparation for the treatment of malignant tumor is characterized in that medical material composition and the percentage by weight of making this Chinese medicine preparation are:
Radix Notoginseng 10-15% Rhizoma Curcumae 5-10% Bulbus Fritillariae Thunbergii 15-25% Rhizoma Atractylodis Macrocephalae 5-15%
Pseudobulbus Cremastrae Seu Pleiones 5-10% Polyporus 5-10% SHECAO 15-25% Herba Scutellariae Barbatae 5-15%
Herba Artemisiae Scopariae 5-10% Radix Astragali 10-20% Radix Glycyrrhizae 5-10%.
Another object of the present invention provides a kind of preparation method for the treatment of the Chinese medicine preparation of malignant tumor, it is characterized in that this method may further comprise the steps:
(1) take by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by weight percentage, temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by weight percentage, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
The present invention is complete, and the side has the effect of blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, pungent drugs can disperse and bitter drugs can descend, active anticancer, be applicable to esophageal carcinoma, gastric cancer, hepatocarcinoma, pulmonary carcinoma, rectal cancer, nasopharyngeal carcinoma, breast carcinoma, cervical cancer, ovarian cancer, lymphoma and cerebroma, thyroid carcinoma, osteocarcinoma etc., can use separately or cooperate put, chemotherapy uses.
The present invention compared with prior art has the following advantages: Chinese medicine preparation of the present invention has significant curative effect to treating malignant tumor, especially to the prevention recurrence after operation shift, to alleviate the toxic and side effects of chemoradiotherapy effect obvious.But it can be by the Chinese medicine factor of a kind of rectifier internal milieu trace element balance disorder; promote organismic internal environment to recover normal; promote the enzyme of regulation and control oncogene to recover normal activity; promote immunologic function to recover normal condition, impel cancerous cell to transform also final full recovery and become normal cell to normal cell.Obey behind the Chinese medicine preparation of the present invention and can alleviate toxic and side effects of chemoradiotherapy in 2-3 days, a few days sees that promptly tumor patient tumor body obviously dwindles, and to advanced carcinoma is painful the persistency analgesic effect is arranged.Various cancer patients all have no adverse reaction and toxic and side effects after obeying Chinese medicine preparation of the present invention, all may reach the effect of relief of symptoms, life-saving.The inventive method technology is simple, can improve the quality of medicine, and can effectively improve the therapeutic effect of clinical drug.
Below by embodiment, technical scheme of the present invention is described in further detail.
The specific embodiment
Embodiment 1
The medical material of present embodiment is formed and percentage by weight is: Radix Notoginseng 10%, Rhizoma Curcumae 5%, Bulbus Fritillariae Thunbergii 15%, the Rhizoma Atractylodis Macrocephalae 5%, Pseudobulbus Cremastrae Seu Pleiones 5%, Polyporus 5%, SHECAO 15%, Herba Scutellariae Barbatae 5%, Herba Artemisiae Scopariae 5%, the Radix Astragali 20%, Radix Glycyrrhizae 10%.
Preparation method: (1) takes by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by above-mentioned percentage by weight, and temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by above-mentioned percentage by weight, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae gross weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
Embodiment 2
The medical material of present embodiment is formed and percentage by weight is: Radix Notoginseng 10%, Rhizoma Curcumae 5%, Bulbus Fritillariae Thunbergii 15%, the Rhizoma Atractylodis Macrocephalae 5%, Pseudobulbus Cremastrae Seu Pleiones 5%, Polyporus 5%, SHECAO 15%, Herba Scutellariae Barbatae 15%, Herba Artemisiae Scopariae 10%, the Radix Astragali 10%, Radix Glycyrrhizae 5%.
Preparation method: (1) takes by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by above-mentioned percentage by weight, and temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by above-mentioned percentage by weight, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae gross weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
Embodiment 3
The medical material of present embodiment is formed and percentage by weight is: Radix Notoginseng 10%, Rhizoma Curcumae 5%, Bulbus Fritillariae Thunbergii 15%, the Rhizoma Atractylodis Macrocephalae 5%, Pseudobulbus Cremastrae Seu Pleiones 5%, Polyporus 10%, SHECAO 25%, Herba Scutellariae Barbatae 5%, Herba Artemisiae Scopariae 5%, the Radix Astragali 10%, Radix Glycyrrhizae 5%.
Preparation method: (1) takes by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by above-mentioned percentage by weight, and temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by above-mentioned percentage by weight, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae gross weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
Embodiment 4
The medical material of present embodiment is formed and percentage by weight is: Radix Notoginseng 10%, Rhizoma Curcumae 5%, Bulbus Fritillariae Thunbergii 25%, the Rhizoma Atractylodis Macrocephalae 5%, Pseudobulbus Cremastrae Seu Pleiones 10%, Polyporus 5%, SHECAO 15%, Herba Scutellariae Barbatae 5%, Herba Artemisiae Scopariae 5%, the Radix Astragali 10%, Radix Glycyrrhizae 5%.
Preparation method: (1) takes by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by above-mentioned percentage by weight, and temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by above-mentioned percentage by weight, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae gross weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
Embodiment 5
The medical material of present embodiment is formed and percentage by weight is: Radix Notoginseng 15%, Rhizoma Curcumae 10%, Bulbus Fritillariae Thunbergii 15%, the Rhizoma Atractylodis Macrocephalae 10%, Pseudobulbus Cremastrae Seu Pleiones 5%, Polyporus 5%, SHECAO 15%, Herba Scutellariae Barbatae 5%, Herba Artemisiae Scopariae 5%, the Radix Astragali 10%, Radix Glycyrrhizae 5%.
Preparation method: (1) takes by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by above-mentioned percentage by weight, and temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by above-mentioned percentage by weight, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae gross weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
Embodiment 6
The medical material of present embodiment is formed and percentage by weight is: Radix Notoginseng 10%, Rhizoma Curcumae 6%, Bulbus Fritillariae Thunbergii 15%, the Rhizoma Atractylodis Macrocephalae 15%, Pseudobulbus Cremastrae Seu Pleiones 6%, Polyporus 6%, SHECAO 15%, Herba Scutellariae Barbatae 5%, Herba Artemisiae Scopariae 6%, the Radix Astragali 10%, Radix Glycyrrhizae 6%.
Preparation method: (1) takes by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by above-mentioned percentage by weight, and temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by above-mentioned percentage by weight, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae gross weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
Embodiment 7
The medical material of present embodiment is formed and percentage by weight is: Radix Notoginseng 11%, Rhizoma Curcumae 6%, Bulbus Fritillariae Thunbergii 18%, the Rhizoma Atractylodis Macrocephalae 6%, Pseudobulbus Cremastrae Seu Pleiones 6%, Polyporus 6%, SHECAO 18%, Herba Scutellariae Barbatae 6%, Herba Artemisiae Scopariae 6%, the Radix Astragali 11%, Radix Glycyrrhizae 6%.
Preparation method: (1) takes by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by above-mentioned percentage by weight, and temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by above-mentioned percentage by weight, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae gross weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
Embodiment 8
The medical material of present embodiment is formed and percentage by weight is: Radix Notoginseng 10%, Rhizoma Curcumae 7%, Bulbus Fritillariae Thunbergii 15%, the Rhizoma Atractylodis Macrocephalae 7.5%, Pseudobulbus Cremastrae Seu Pleiones 7%, Polyporus 7%, SHECAO 15%, Herba Scutellariae Barbatae 7.5%, Herba Artemisiae Scopariae 7%, the Radix Astragali 10%, Radix Glycyrrhizae 7%.
Preparation method: (1) takes by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by above-mentioned percentage by weight, and temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by above-mentioned percentage by weight, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae gross weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
The usage and dosage of the present invention " day lucky star " Chinese medicine preparation: clinically be used according to the state of an illness, stadium and individual variation principal agent, accessory drugs, be a course of treatment February, and decide on the state of an illness course of treatment, can take continuously four to six months according to the state of an illness.
The mechanism of action of the present invention's " day lucky star " Chinese medicine preparation:
1. some active anticancer component of " day lucky star " has special affinity to human tumor, taking the most of medicine in back accumulates in around the tumor, form focus topical remedy high concentration region, the part active ingredient enters inside tumor, directly kill tumor cell, make its necrosis, softening, absorption, reach the effect that " gathering is assaulted fortified position " directly kills tumor cell.
2. changing " soil " that " tumor microenvironment " lose tumor cell to depend on for existence does not attack from going out.Correct simultaneously in the body " ecological environment ", eliminate virulence factor and make body thoroughly break away from the unbalance pathological state of internal organs.
3. " day lucky star " contained canker medical material composition (mainly containing effective constituent is PDE) can make carcinoma basilar part cell " apoptosis ", urges the Fructus Mali pumilae precocity as medicine, and it is the same that it is come off naturally.
4. by activating body's immunity, inducing immune cells produces tens of kinds of cytokines of regulating tumour immunity, as interleukin, tumor necrosis factor, interferon, colony-stimulating factor etc., these active factorses surround, engulf, kill tumor cell and residual tumor fragment of tissue from the outside.
5. cut off and close the tumor body, make tumor cell lose nutrition supply and can't grow, breed for the required vasoganglion of Ji, thus the atrophy necrosis.
6. protection bone marrow and gastrointestinal mucosal increase diet, make the patient have good performance status all the time.
The drug effect characteristics of the present invention's " day lucky star " Chinese medicine preparation:
1. with strong points, evident in efficacy: " day lucky star " medicine series is the individualized treatment medication of preparing according to different patients' the concrete state of an illness, be fit to this patient.As new anticancer therapy method, it has farthest embodied the basic principle of traditional medicine " determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs ", so evident in efficacy after taking.Aspect anticancer therapy, phenomenon and the edible health care product abuse phenomenon of having avoided a kind of medicine all kinds of diseases and ailments to guarantee to cure.
2. anticancer high specificity, instant effect: basic research shows that some active anticancer component in " day lucky star " medicine can directly enter inside tumor, destroys and kills tumor cell, makes tumor position necrosis from central division, softens, absorbs, and makes cancerous cell " apoptosis ".Clinical manifestation is that cancer pain is alleviated after the medication, lump dwindles, ascites pleural fluid reduces.
3. effect is lasting, difficult repeatedly: " day lucky star " medicine belongs to Chinese medicine preparation, and it is to reach anticancer purpose by the whole body therapeutic effect.On the one hand: specific killing tumor cell (eliminating evil effect); On the other hand:, dispel pathogenetic gene (centralizing function) by activating body's immunity.
4. can significantly improve patient with advanced cancer quality of life, make the patient obtain for a long time " band tumor existence ": specific aim anticancer therapy systematically, can make most of cancer patient's clinical symptoms in late period, as: breathe hard, cough, pain, abdominal distention, ascites pleural fluid, difficulty in urination and defecation, feel sick, vomiting etc. is alleviated in a short time or disappear.Make to threaten the common sympton of patient with advanced cancer existence to be removed, life is taken care of oneself gradually, and anticancer confidence strengthens, and tumor is further controlled, and realizes the hope of " existence of band tumor ".
5. to effective treatment of cancerous ascites pleural fluid, make the patient regain new life: cancerous ascites pleural fluid is the clinical common sympton of patients with terminal, its appearance brings psychology and huge pressure and the threat of health to the patient, the patient usually occurs serious breathing hard, has palpitation, abdominal distention, conventional western medical treatment is invalid, the state of an illness increases the weight of day by day, and quality of life goes from bad to worse, and the characteristic medical treatment of " day lucky star " has solved the difficult problem in this clinical tumor field effectively.Make the cancerous ascites pleural fluid patient regain new life.
The clinical experiment of the present invention's " day lucky star " Chinese medicine preparation:
The present invention observes case 15000 many cases, has mainly comprised aspects such as digestive system, respiratory system, gynecological tumor, breast tumor and cancerous ascites pleural fluid, generally believes that " day lucky star " has following characteristics:
1, anticancer wide spectrum: think that anticancer wide spectrum is because " day lucky star " belongs to serial anticancer drugs, to different diseases with different medicines; Promptly be that the used therapeutic scheme of the different patient of same disease is also different.
2, effective percentage height, effect are alleviated the back and are difficult for repeatedly lastingly: research thinks that the anticancer mechanism of these characteristics and " day lucky star " has direct relation.
3, can promote the quality of life of patient with advanced cancer significantly, prolong life cycle: thus after most of patients is taken medicine soon, will experience clinical malaise symptoms and obviously be alleviated, the patient is anticancer full of confidence.
4, can eliminate cancerous ascites pleural fluid and pericardial effusion fast: terminal cancer common complication-cancerous ascites pleural fluid, pericardial effusion, it is the knotty problem of tumor clinic, the conventional therapy means are difficult to gather effect, " day lucky star " can make its patient's clinical symptoms of about 91% be eased, ascites pleural fluid disappears gradually, quality of life is improved, and prolonged life cycle.
5, as the anticancer drugs of therapeutic type, " day lucky star " preparation is flexible, and principal agent, accessory drugs are used, Special medicine for special disease.
6, have no side effect, can take for a long time.
The clinical advantage of the present invention's " day lucky star " Chinese medicine preparation:
Traditional Chinese medical science curing oncoma, the traditional Chinese medical science of seeing through the appearance to perceive the essence has its original one side to the understanding of tumor.Human righteousness's deficiency, its gas must be empty, on the surface, though patient's tumor is sent out in parts such as lung, stomach, livers, is that the deficient of whole body causes in essence.Therefore, the total Therapeutic Principle of tumor should be a strengthening vital QI to eliminate pathogenic factors.The traditional Chinese medical science mainly adopts differential diagnosis of diseases to combine with dialectical to tumor treatment, sets upright with eliminating evil to combine, and treatment by oral administration of medicines combines with external treatment, the Therapeutic Principle that the traditional Chinese medical science combines with modern medicine.In modern medicine treatment neoplastic process, traditional Chinese medical science combined treatment tumor, alleviate put, chemical therapy toxic side effect, positive role has been brought into play in operation sequela aspect, has improved patient's life quality effectively, has prolonged survival time of patients.The advantage of Chinese medicine is that at first, it all can use in each stage of oncotherapy; Secondly, strengthening vital QI to eliminate pathogenic factors but just do not hinder, i.e. help is not looked for trouble.The advantage of Chinese medicine is embodied in replenishing the modern medicine treatment means.As the back cooperation treatment by Chinese herbs of performing the operation, can accelerate post-operative recovery; Use with chemicotherapy is collaborative, can alleviate its side effect, improve curative effect.The present invention relates to a kind of Chinese medicine preparation (" day lucky star " serial cancer therapy drug prescription) for the treatment of malignant tumor and preparation method thereof, in tumor therapeutic procedure, has following unique effects: through systematic study to " seven medicines among the people ", the scientific research group has been found the universal law that active plant is anticancer, " the anticancer arousal theory of active plant " proposed first, by drug effect to " day lucky star ", pharmacological research and preparation technology's research, state-of-the-art technologies such as " nanotechnologys " that the scientific research group will " be imitated the supersonic leaching technology " entirely is applied in the production technology of " day lucky star ", and is developed into suitable multiple carcinoma medicine series according to the kind and the clinical essential difference of tumor.Compare " ' day lucky star ' series " medicine (Rhizoma Pedicularis Davidii capsule, the capsule of living again, the kind celestial capsule of dragon) with " day lucky star " medicine following characteristics are arranged: new technology has kept the active anticancer component of medicine to greatest extent, has improved anticancer effective percentage and clinical cure rate greatly; Activity " seven medicines " after essence is got makes a new generation's " day lucky star " medicine tumour inhibiting rate higher, and specific killing power is stronger, thereby has reduced the tumor recurrence rate and the rate of transform significantly; The use of Special medicine for special disease has solved the clinical tumor difficult and complicated illness, as: the problem that cancerous ascites pleural fluid, cancerous pain, digestive tract tumor etc. can't effectively treat; Integral body has improved patient's cellular immune function and humoral immune function; " day lucky star series " medicine belongs to nontoxic level, can take for a long time.
1, with the postoperative life quality and the long term survival rate that can effectively improve the patient that cooperate of performing the operation.
Before the operation, prepare, improve some organ function of patient, after one's own heart, liver, renal function, correct anemia, improve patient's body constitution etc. for ocal resection.Should recover body constitution as early as possible after the operation, alleviate postoperative untoward reaction, not smooth etc. as low grade fever, hyperhidrosis, inappetence, abdominal part flatulence, stool, and because the dysfunction that operation is caused, gastrointestinal dysfunction as digestive tract tumor's postoperative, anastomositis due to the dumping syndrome, bile reflux etc.
Obey " day lucky star " serial cancer therapy drug behind the surgery recovery for a long time, except that improving body constitution, can also improve immunologic function,, improve long term survival rate to improve the ability of body anti-recurrence, transfer.Disease early lesion limitation, peripheral lymph node and organize and do not see transfer, postoperative is not generally done chemotherapy or radiotherapy, and only with the treatment by Chinese herbs long-term observation.Or the patient after postoperative process radiotherapy or the chemotherapy, even end-stage patients, the patient that postoperative can not carry out chemotherapy, radiotherapy also can use the Chinese medicine long-term observation.If with " day lucky star " serial cancer therapy drug the kidney invigorating, nourish blood, spermatogenesis, can accelerate to recover, reach the said promoting leucocytes of modern medicine, hematoblastic purpose.
2, in radiotherapy, be used the untoward reaction that this medicine can alleviate radiotherapy and can improve combined therapy effect.
Often occur Inflammation of Radioactive Oral Cavity, radiation esophagitis, chest radiotherapy in the tumor of head and neck radiotherapy and occur often often occurring in radiation pneumonia, the abdominal irradiation radiation rectitis, cystitis etc. often occurring in gastroenteritis due to radiation and the hypogastric region radiotherapy, all can use treatment by Chinese herbs and can obtain curative effect preferably.According to theory of Chinese medical science, prevent and treat these toxicities when with supplementing QI and nourishing YIN, promote the production of body fluid moisturize, rules such as invigorating the spleen and regulating the stomach, nourishing the liver and kidney and heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling treat, and according to different parts and disease determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs.
Use " day lucky star " serial cancer therapy drug after radiotherapy, energy human body immunity improving function is recovered the damage of lonizing radiation to important organ as early as possible, to reduce the recurrence and the transfer of tumor, improves long term survival rate.
3, be used this medicine treatment in the chemotherapy intermission and can alleviate the normal function that its toxicity is protected each internal organs.
Common dizziness and blurred vision, soreness of the waist and knees, lethargy, inappetence, insomnia and dreamful sleep, defecation imbalance etc. after the chemotherapy.Above symptom Chinese medical discrimination belongs to the disease of QI and blood deficiency, deficiency of the liver and kindey, and the medicine of available benefiting QI and nourishing blood, nourishing the liver and kidney makes patient's chemotherapy side effect sx.See loss of appetite, nausea and vomiting, stomachache, diarrhoea etc. after the chemotherapy, Chinese medical discrimination belongs to that taste are become estranged, the performance of lifting mistake department, can invigorating the spleen and regulating the stomach, and the treatment of stopping nausea and vomiting by lowering the adverse flow of QI method.Most antitumor drug can cause bone marrow depression in various degree.Therefore, prevent that hemogram from descending is a big problem of chemotherapeutic period, whole chemotherapeutic period all can cooperate " day lucky star " serial cancer therapy drug, and to alleviate the toxicity of chemotherapy, protection bone marrow promotes the recovery and the reconstruction of bone marrow hematogenesis function.
According to the minimizing of hemocyte different components, according to the dialectical experimental studies results of Chinese medicine as a result, Chinese medicine is selected for use also and is given priority to.Because cancer therapy drug is to the infringement of liver; common both sides of the chest dull pain after the chemotherapy; nausea and vomiting, anorexia are greasy; limb is soft weak, or with jaundice, hepatosplenomegaly, the check abnormal liver function; greasy fur on tongue, matter have purple gas or ecchymosis; thready and stringy pulse can adopt the blood stasis dispelling detoxifcation, and the harmonizing the liver and spleen method is treated with the liver protecting function.
Because the application of metal platinum medicine in antineoplaston; renal function injury often appears; make the empirical value of blood urea nitrogen (BUN) and creatinine (Cr) occur unusual; often with soft weak, the poor appetite of limb, waist soreness, the urine amount is few; or edema; pale tongue is and fat, and thin lingual fur, deep-thready pulse disease adopt " day lucky star " serial cancer therapy drug strengthening spleen, tonifying kidney, the treatment of blood stasis dispelling disintoxication can protect renal function.
The present invention's " day lucky star " is through several years clinical practices such as Affiliated Hospital of Xi'an Jiaotong University Medical College, Affiliated Hospital of The Fourth Military Medical University, 323 hospitals of PLA.This medicine is safe and reliable in regulation clinical dosage scope, has no side effect." day lucky star " clinical observation 105 examples can obviously be improved the clinical symptoms of the traditional Chinese medical science based on the malignant tumor of pulmonary carcinoma, and its total effective rate is 82.86%.Can improve tumor patient immunologic function and life quality, its coefficient of stabilization is 90.48%; To tcm symptom: spiritlessness and weakness, have a dizzy spell, shortness of breath and palpitation, lustreless complexion, inappetence and tongue, pulse condition effect significantly (P＜0.05), average before and after OKT3, OKT4, OKT4/KOT8, the NK treatment is compared (P＜0.05 or P＜0.01), and there were significant differences, is the effective medicine of a kind of treatment malignant tumor." day lucky star " do not find obvious adverse reaction in treatment malignant tumor process, be the antitumor Chinese medicine of a determined curative effect, is worthy of popularization.
Claims (2)
1. Chinese medicine preparation for the treatment of malignant tumor, the medical material that it is characterized in that making this Chinese medicine preparation forms and percentage by weight is:
Radix Notoginseng 10-15% Rhizoma Curcumae 5-10% Bulbus Fritillariae Thunbergii 15-25% Rhizoma Atractylodis Macrocephalae 5-15%
Pseudobulbus Cremastrae Seu Pleiones 5-10% Polyporus 5-10% SHECAO 15-25% Herba Scutellariae Barbatae 5-15%
Herba Artemisiae Scopariae 5-10% Radix Astragali 10-20% Radix Glycyrrhizae 5-10%.
2. prepare a kind of method for the treatment of the Chinese medicine preparation of malignant tumor as claimed in claim 1, it is characterized in that this method may further comprise the steps:
(1) take by weighing Radix Notoginseng, Rhizoma Curcumae, Bulbus Fritillariae Thunbergii, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Cremastrae Seu Pleiones and Polyporus by weight percentage, temperature is lower than 60 ℃ of dryings, is ground into 80 order fine powders, and mix homogeneously is standby;
(2) take by weighing SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae by weight percentage, 10 times of water gagings that add described SHECAO, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae, the Radix Astragali and Radix Glycyrrhizae weight, decoct 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate decompression is concentrated into 65 ℃ of survey relative densities and is the thick paste of 1.30-1.35, and is standby;
(3) with the fine powder of mix homogeneously in the step (1) and the thick paste mix homogeneously in the step (2), 60 ℃ of dryings of temperature are ground into 80 order fine powders, mixing, and it is an amount of to add water, promptly.
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