CN101389213B - Pufa聚酮化合物合酶系统及其用途 - Google Patents

Pufa聚酮化合物合酶系统及其用途 Download PDF

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CN101389213B
CN101389213B CN200480014646.XA CN200480014646A CN101389213B CN 101389213 B CN101389213 B CN 101389213B CN 200480014646 A CN200480014646 A CN 200480014646A CN 101389213 B CN101389213 B CN 101389213B
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seq
structural domain
pufa
schizochytrium
nucleic acid
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CN101389213A (zh
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詹姆斯·G·梅茨
克雷格·A·韦弗
威廉·R·巴克利
詹姆斯·H·弗拉特
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DSM IP Assets BV
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DSM IP Assets BV
Martek Biosciences Corp
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CN200480014646.XA 2003-03-26 2004-03-26 Pufa聚酮化合物合酶系统及其用途 Expired - Fee Related CN101389213B (zh)

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US45797903P 2003-03-26 2003-03-26
US60/457,979 2003-03-26
PCT/US2004/009323 WO2004087879A2 (en) 2003-03-26 2004-03-26 Pufa polyketide synthase systems and uses thereof

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CN101389213A CN101389213A (zh) 2009-03-18
CN101389213B true CN101389213B (zh) 2014-05-28

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EP (1) EP1623008B1 (https=)
JP (3) JP2007524377A (https=)
KR (3) KR101234199B1 (https=)
CN (1) CN101389213B (https=)
AU (2) AU2004225485B2 (https=)
BR (1) BRPI0409046A (https=)
CA (1) CA2520396C (https=)
ES (1) ES2516641T3 (https=)
IL (1) IL200625A0 (https=)
MX (2) MX341785B (https=)
WO (1) WO2004087879A2 (https=)

Families Citing this family (20)

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US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
US7211418B2 (en) 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US8003772B2 (en) * 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US7217856B2 (en) 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
KR20070073986A (ko) 2000-01-28 2007-07-10 마텍 바이오싸이언스스 코포레이션 발효기 내에서 진핵 미생물의 고밀도 배양에 의한고도불포화 지방산을 함유하는 지질의 증진된 생산 방법
EA200800225A1 (ru) 2005-07-01 2008-06-30 Мартек Байосайенсиз Корпорейшн Содержащий полиненасыщенные жирные кислоты маслопродукт и его применения и получение
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
WO2007106905A2 (en) 2006-03-15 2007-09-20 Martek Biosciences Corporation Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems
EP2415360A3 (en) * 2006-08-29 2012-02-29 Martek Biosciences Corporation Use of DPA(n-6) oils in infant formula
EP2405018A4 (en) * 2009-03-04 2013-02-20 Univ Miyazaki METHOD FOR DETERMINING THE FATTY ACID SYNTHESIS PATH OF A MICROORGANISM AND PCR PRIMER FOR THIS METHOD
ES2752196T3 (es) * 2009-03-16 2020-04-03 Dsm Ip Assets Bv Producción de proteínas en microorganismos del filo Labyrinthulomycota
US8940884B2 (en) 2009-03-19 2015-01-27 Dsm Ip Assets B.V. Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof
EP2614829A1 (en) * 2012-01-11 2013-07-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Mammalian neural plate border stem cells capable of forming neural tube and neural crest cell lineages including central and peripheral neurons
KR101570771B1 (ko) 2013-11-18 2015-11-23 대한민국 고도불포화지방산 생합성을 위한 재조합 벡터 및 이를 이용하여 제작된 형질전환 식물체
JP6682109B2 (ja) * 2015-01-09 2020-04-15 国立大学法人 宮崎大学 ヤブレツボカビ類を用いたリグニン分解活性を有するタンパク質の製造方法
PL3455351T3 (pl) 2016-05-12 2022-11-21 Dsm Ip Assets B.V. Sposób zwiększania wytwarzania wielonienasyconych kwasów tłuszczowych omega-3 w mikroalgach
US12241101B2 (en) 2018-08-10 2025-03-04 Kyowa Hakko Bio Co., Ltd. Microorganism producing polyunsaturated fatty acid and method for producing polyunsaturated fatty acid
BR112021002300A2 (pt) * 2018-08-10 2021-05-04 Kyowa Hakko Bio Co., Ltd microrganismo que produz ácido eicosapentaenoico e método para a produção de ácido eicosapentaenoico

Citations (1)

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US6140486A (en) * 1997-06-04 2000-10-31 Calgene Llc Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340742A (en) * 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
US6677145B2 (en) * 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US7247461B2 (en) * 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
EP1911837B1 (en) * 2000-09-28 2011-05-25 Bioriginal Food & Science Corp. FAD5-2 fatty acid desaturase family member and uses thereof
US6912470B2 (en) * 2001-05-21 2005-06-28 Ecopia Biosciences, Inc. Genes and proteins involved in the biosynthesis of enediyne ring structures
TWI337619B (en) * 2001-04-16 2011-02-21 Martek Biosciences Corp Pufa polyketide synthase systems and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140486A (en) * 1997-06-04 2000-10-31 Calgene Llc Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants

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EP1623008A4 (en) 2009-05-27
BRPI0409046A (pt) 2006-04-18
ES2516641T3 (es) 2014-10-31
WO2004087879A2 (en) 2004-10-14
JP2007524377A (ja) 2007-08-30
AU2008249169A1 (en) 2008-12-11
EP1623008B1 (en) 2014-07-30
CN101389213A (zh) 2009-03-18
MX341785B (es) 2016-09-01
KR101234199B1 (ko) 2013-02-20
AU2004225485A1 (en) 2004-10-14
KR20120123726A (ko) 2012-11-09
JP6134361B2 (ja) 2017-05-24
WO2004087879A3 (en) 2008-07-24
EP1623008A2 (en) 2006-02-08
HK1088632A1 (en) 2006-11-10
KR101234200B1 (ko) 2013-02-19
KR20060006014A (ko) 2006-01-18
KR20120097502A (ko) 2012-09-04
MXPA05010214A (es) 2005-12-14
JP2016000048A (ja) 2016-01-07
CA2520396C (en) 2016-08-09
KR101234198B1 (ko) 2013-02-19
AU2008249169B2 (en) 2012-03-15
IL200625A0 (en) 2011-07-31
CA2520396A1 (en) 2004-10-14
AU2004225485B2 (en) 2008-08-21
JP5890791B2 (ja) 2016-03-22
JP2013143945A (ja) 2013-07-25

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