CN101375924A - Externally appiled Chinese medicinal composition for treating chronic psoriasis in resting stage - Google Patents

Externally appiled Chinese medicinal composition for treating chronic psoriasis in resting stage Download PDF

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CN101375924A
CN101375924A CNA2008101572591A CN200810157259A CN101375924A CN 101375924 A CN101375924 A CN 101375924A CN A2008101572591 A CNA2008101572591 A CN A2008101572591A CN 200810157259 A CN200810157259 A CN 200810157259A CN 101375924 A CN101375924 A CN 101375924A
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parts
combination
medicine
blood
treating chronic
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路敦祥
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Abstract

The invention discloses an external traditional Chinese medicine combination for treating chronic psoriasis in the resting stage, which is composed of the raw materials of the traditional Chinese herbal medicine by weight parts as follows: 120 parts of realgar, 120 parts of sulfur, 120 parts of camphor, 120 parts of dried alum, 120 parts of alum, 60 parts of bichromate, 120 parts of copperas, 15 parts of child tea and 240 parts of lateral branch leaves. According to compatibility of the medicines, the combination has the effects of clearing heat and drying damp, removing pattogenic heat from the blood and toxic material from the body, destroying parasites and relieving itching, as well as moistening skin and promoting granulation. The combination of the medicines ensures the particularly strong antibacterial effect, and serves the functions of clearing heat and drying damp, removing pattogenic heat from the blood and toxic material from the body, as well as destroying parasites and relieving itching. Through the external application, the combination directly acts on the focus, thereby improving local lesion tissue, promoting metabolism, and increasing local absorption of the medicament.

Description

The Traditional Chinese Medicine for external application compositions of treatment chronic psoriasis in resting phase
Technical field
The present invention relates to the application compress goods, especially treat the liniment of recurrent dermatosis (psoriasis).
Background technology
Psoriasis is a kind of chronic patch squama dermatosis of outbreak repeatedly, claims psoriasis again.Chinese medicine claims tinea alba or psoriasis.Primary disease does not have infectiousness, and to see winter, the juvenile era of being everlasting begins more.Near normal sending out scalp and extremity body face, especially elbow and knee joint, the blood rash or the speckle of the silvery white squama of multilamellar is stamped in the part, petechial hemorrhage arranged after scraping off squama and following shinny thin film thereof, and gargalesthesia is arranged.Often alleviate or spontaneous recovery, worsen winter or recurrence summer.General two kinds of external used medicine therapies of western medical treatment and constitutional treatment.Common drug has keratoplastics and corticosteroid cream.The former medicine removes has chafe, improve outside the local microcirculation effect, and it is synthetic to have RNA interfering, and Profilin is synthetic, lowers the mitosis effect.Be coated with except latter's medicine and add outside the package, also available predniso lone acetate adds that equivalent 1% Anuject is made skin lesion and sealing down.Constitutional treatment has immunosuppressant, and common drug has methopterin, ethyliminum, bimolane, hydroxyurea etc.This class adverse effect is more.Also has retinoic acid, antibiotic etc.Have loose wind soup, YUJIN YINXIE PIAN, Radix Salviae Miltiorrhizae Tabellae, Radix Tripterygii Wilfordii tablet of FUFANG QINGDAI WAN, Radix Arnebiae (Radix Lithospermi) speckle removing soup, removing heat from blood oral in the tcm therapy, above medicine all has certain curative effect, but can not effect a radical cure.Therefore, still there is demand in people to the Chinese medicine preparation of the better treatment of curative effect.Up to now, also do not find any relevant bonded report of medicine of the present invention.
Recurrent dermatosis (psoriasis) generally is divided into resting stage and carries out the phase, and resting stage, symptom was presented as that erythra is kermesinus, no longer continues to enlarge, the skin Fructus Citri tangerinae is thick, the phase of carrying out symptom is presented as that erythra squama not of uniform size is few and it is more to damage, and inflammation is obvious, and what the present invention relates to is resting stage
Summary of the invention:
The object of the invention just provides a kind of Traditional Chinese Medicine for external application compositions of effecting a radical cure chronic psoriasis in resting phase.
For achieving the above object, the present invention is made up of following parts by weight of Chinese traditional medicine raw material:
240 parts on 120 parts of Realgars, 120 parts of sulfurs, 120 parts of Camphoras, 120 parts of dried Alumens, 120 parts in Alumen, 60 parts of Arsenicum sablimatum, 120 parts of Melanteritum, 15 parts of Catechu and side shoot leaf
Realgar of the present invention is Chinese red, and is translucent, and crystal face has adamantine luster, the existing resinous luster of fracture, and hardness 1.5-2.0, proportion 3.5, cleavage is more complete, the crisp crystalline solid of property, chemical constituent is AsS.
Alumen of the present invention (being Alumen) is colourless transparent crystal, and tart flavour is arranged, and is water-soluble.Generate the gluey precipitation of aluminium hydroxide during hydrolysis.Chemical formula is K 2SO 4.AI 2(SO 4) 3.24H 2O 4
Arsenicum sablimatum of the present invention (Arsenicum sablimatum) contains arsenic minerals stone and is processed into: the impurity of arsenous acid anhydride, also name " Arsenicum sablimatum " sublimation purifying then obtains arsenicum.Equal trioxygen-containingization two arsenic.AS 2O 3
Catechu of the present invention is the dry soft extracts of the peeling branch of leguminous plant catechu ACACIA CATECHU (LF) WILLD, and surperficial sepia or pitchy are had gloss slightly, matter is crisp, and easily broken, section is irregular, pore is arranged, and meeting tide has stickiness, the crystalline solid of odorless puckery hardship.
Cacumen Platycladi of the present invention is the dry branch tip and leaf of Cupressaceae plant Cacumen Platycladi Platycladus.orientalis (li) Franco.
Pharmacology analysis of the present invention is as follows: medicament selection Realgar of the present invention, sulfur, Camphora, dried Alumen, Alumen, Arsenicum sablimatum, Melanteritum, Catechu, Cacumen Platycladi make up.Make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat psoriatic recurrence.Wherein select Realgar, Xin Wen for use, return large intestine channel, antibiotic, expelling wind and removing dampness, the detoxifcation parasite killing is warded off dirty antipruritic; Sulfur, Alumen, acid temperature; Return large intestine channel, the external parasite killing that can detoxify, dampness removing to stop itchin is treated the eczema scabies.Bai Fan, Alumen (calcined), the raw cold of Melanteritum acid, the energy heat-clearing and toxic substances removing, removing dampness and killing parasites is held concurrently and can be removed the rotten and let fresh grow.Three kinds of alum flours do not have mycostasis to Pilus Caprae seu Ovis sample sporidiole bacteria, trichophyton, Cryptococcus histolyticus, Candida albicans etc. in culture dish.Can be combined to the proteinate in water hard to tolerate with protein, so the cutin of loosening, Melanteritum master sulfur acid is ferrous, white sail sulfur acid potassium aluminum, and both pharmacology are similar.Camphora dehumidifying parasite killing, and can pain relieving.Arsenicum sablimatum acid Wen Han, very toxic, external removing the necrotic tissue parasite killing.The Catechu master contains tannic acid, and staphylococcus aureus and bacillus pyocyaneus etc. is had inhibitory action, and can removing dampness expelling pus and promoting granulation, heat clearing and blood cooling, dampness and detoxifying.The Cacumen Platycladi clearing away heat and cooling blood, and the effect of antiinflammatory, anti-bacteria and anti-virus is arranged.Above-mentioned all medicine compatibilities have heat clearing and damp drying, removing pathogenic heat from blood and toxic substance from the body, killing parasites for relieving itching, the effect of skin moistening granulation promoting.It is strong especially that all medicines share antibiotic effect, plays heat clearing and damp drying altogether, removing pathogenic heat from blood and toxic substance from the body, the merit of killing parasites for relieving itching.Apply ointment or plaster by external, directly act on focus, improve local disease and decrease tissue, enhance metabolism, and increase medicine in partial absorption.And the treatment effect of institute's medication before the performance.
Pharmacological research confirms, clinically can be used for chronicly, and subacute skin lesion soaks into plump person, and colour of skin spot sufferings are given prominence to the person, and acute stage is avoided usefulness.
Medicine of the present invention is poisonous product, never oral administration.The fried pungent and sour-sweet property food of diet is eaten fresh vegetables more.
Medicine of the present invention can clinical conventional method with Chinese medicine preparation be prepared into any conventional external preparation or cream.For example these crude drug can be made powder mixes and evenly make powder, be sprinkling upon on the plaster and stick.Can be coated with outward with Cera Flava or benzoic acid mixing furnishing ointment, gauze is fixed then, can also make cream, liquid medicine etc.
The activity combination of medicine of the present invention can add various conventional adjuvant required when preparing different dosage form, and as lubricant, adhesive etc. are prepared into any normal outer varnish with the method for Chinese medicinal of routine.
The specific embodiment
Embodiment one: accurately take by weighing Realgar 120g, sulfur 120g, Camphora 130g, dried Alumen 120g, Alumen 120g, Arsenicum sablimatum 60g, Melanteritum 120g, Catechu 15g and side shoot leaf 240g.With levigate mistake 120 mesh sieves of above-mentioned raw materials difference, uniform mixing is made powder, is sprinkling upon on the plaster to stick.
Embodiment two: get powder that embodiment one makes and Cera Flava and mix thoroughly and make ointment and smear.
Embodiment three, get medicine that embodiment one takes by weighing and add that water decocts repeatedly, filtering residue stays liquid medicine to concentrate back spraying or obliterating affected part.
Below further set forth the high effect of having of medicine of the present invention by testing example.These test examples have comprised the pharmacodynamics test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The present invention passed through for 11 years, accepted clinic case 318 people altogether for medical treatment, with the treatment of continuous 90 days of medicine of the present invention, observed local red, bits, swollen symptom and healing time every day, and is as follows through perusal:
Figure A200810157259D00061
As can be seen, 318 routine patients are through trimestral treatment, produce effects 280 examples, 28 examples that take a turn for the better, invalid 10 examples, effective percentage 96.9 from above-mentioned table.
Model case:
Kingly way water, the man, 46 years old, the teacher ill 10 years, introduced use medicine of the present invention through colleague Chen Xing and now fully recovers.
Zhou Guifang, the woman, 37 years old, the inventor sister in law, ill 7 years, through how family treated but does not feel any better.Do not recur through using medicine of the present invention now to fully recover in 60 days.
Zhai Yanfang, the woman, 67 years old, the inventor wife of father's younger cousin, ill 13 years, bad when curing state of an illness fashion in many ways, quality of life descended.Future life had no confidence.But use not recurrence of medicine of the present invention recovery from illness in 90 days.

Claims (1)

1, a kind of Traditional Chinese Medicine for external application compositions for the treatment of chronic psoriasis in resting phase is characterized in that, it is made up of following parts by weight of Chinese traditional medicine raw material:
240 parts on 120 parts of Realgars, 120 parts of sulfurs, 120 parts of Camphoras, 120 parts of dried Alumens, 120 parts in Alumen, 60 parts of Arsenicum sablimatum, 120 parts of Melanteritum, 15 parts of Catechu and side shoot leaf.
CNA2008101572591A 2008-09-27 2008-09-27 Externally appiled Chinese medicinal composition for treating chronic psoriasis in resting stage Pending CN101375924A (en)

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Application Number Priority Date Filing Date Title
CNA2008101572591A CN101375924A (en) 2008-09-27 2008-09-27 Externally appiled Chinese medicinal composition for treating chronic psoriasis in resting stage

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103735582A (en) * 2014-01-02 2014-04-23 姬泽木 Traditional Chinese medicine for treating psoriasis and preparation method of tradition Chinese medicine
CN105560380A (en) * 2015-09-18 2016-05-11 苏珉 Traditional Chinese medicine for treating vocal leukoplakia
CN117137945A (en) * 2023-09-20 2023-12-01 陕西科技大学 Application of ferrous ions in preparation of medicines for inhibiting or treating infection or disease caused by candida albicans

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103735582A (en) * 2014-01-02 2014-04-23 姬泽木 Traditional Chinese medicine for treating psoriasis and preparation method of tradition Chinese medicine
CN105560380A (en) * 2015-09-18 2016-05-11 苏珉 Traditional Chinese medicine for treating vocal leukoplakia
CN117137945A (en) * 2023-09-20 2023-12-01 陕西科技大学 Application of ferrous ions in preparation of medicines for inhibiting or treating infection or disease caused by candida albicans

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Open date: 20090304