CN110141608B - Mongolian medicine composition for treating thyroid diseases and preparation method of pills thereof - Google Patents
Mongolian medicine composition for treating thyroid diseases and preparation method of pills thereof Download PDFInfo
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Abstract
The invention provides a Mongolian medicine composition for treating thyroid diseases, which is prepared from antler, selfheal, scallop adductor ash, sea buckthorn, rhodiola rosea, monkshood, isatis root, gentiana rigescens, corydalis edulis and pharbitis seed. The Mongolian medicine pill is flat in nature, is a good prescription for breaking stuffiness, mainly takes Szechwan juniper herb, Szechwan horn, scallop tooth ash, common selfheal fruit-spike, pharbitis seed and radix aconiti which are used as medicines for drying pus blood as main materials, is matched with sea buckthorn for removing blood stasis and diluting blood, has rhodiola rosea, Damnacanthus flaccida and isatis root for relieving fever, and has corydalis edulis for clearing heat and relieving swelling. Is mainly used for treating goiter, tubercle, cystic tubercle of thyroid, thyroid tumor and disintegrating mass, and is prepared into pills which are convenient to take and carry.
Description
Technical Field
The invention belongs to the technical field of Mongolian medicines, and particularly relates to a Mongolian medicine composition for treating thyroid diseases and a preparation method of pills thereof.
Background
Thyroid diseases belong to the category of "goiter diseases" in traditional Chinese medicine, and with the changes of working pressure, eating habits and life styles of people, more and more people begin to suffer from thyroid diseases. The causes of thyroid diseases are mainly emotional internal injury, improper diet, water and soil, congenital factors, etc. Liver qi is disturbed and regulated due to anger or anxiety for a long time, body fluid can not return to normal and is coagulated into phlegm, qi stagnation and phlegm coagulation, stasis and accumulation in the neck form goiter; the spleen and stomach function, spleen dysfunction, qi and blood circulation disorder, phlegm accumulation due to warm accumulation, and goiter due to phlegm and qi stagnation in the neck are affected by improper diet or water and soil; if the family has a history of thyroid diseases, the incidence rate of the thyroid diseases in the later generations is higher.
Most thyroid diseases such as goiter, nodules, cystic nodules of the thyroid, thyroid tumor and broken lump are benign lesions, and most of the western medicine treatment thyroid diseases are treated by medicaments such as thyroxine and the like, but the recurrence rate is high, the curative effect is not stable, and the long-term oral administration of thyroxine easily causes various side effects and adverse reactions; surgical resection treatment is also prone to temporary or permanent hypothyroidism and is generally not acceptable to patients.
Disclosure of Invention
The invention aims to solve the technical problem that the traditional Chinese medicine composition for treating thyroid diseases is flat in physical property, is a good prescription for breaking the lumps, mainly comprises dry Hiriyasu, medicaments for drying pus and blood, namely antler, scallop tooth ash, common selfheal fruit-spike, pharbitis seed and radix aconiti carmichaeli, is matched with sea buckthorn for removing blood stasis and diluting blood, and is used for relieving fever by rhodiola rosea, gentiana flaccida and isatis root, and corydalis edulis is used for clearing heat and reducing swelling. The Mongolian medicine composition for treating thyroid diseases has no side effect and good curative effect.
In order to solve the technical problems, the invention adopts the technical scheme that: a Mongolian medicine composition for treating thyroid diseases is prepared from the following raw materials in parts by weight: 3 parts of antler, 2.4 parts of selfheal, 2.4 parts of scallop dust, 2.4 parts of sea-buckthorn, 2.4 parts of rhodiola root, 2.4 parts of monkshood, 2.4 parts of isatis root, 2.4 parts of gentiana damascena, 2.4 parts of corydalis tuber and 2.4 parts of pharbitis seed.
Deer horn: sweet, salty and warm in nature. Has the effects of invigorating kidney yang, promoting blood circulation, relieving swelling, promoting blood circulation, and removing blood stasis.
Selfheal: clearing away heat, dissipating nodulation and relieving swelling.
Scallop tooth ash: pungent and bitter taste, warm nature, the action of breaking stuffiness, dryness-dispelling and synergistically acting on Niulasu, stopping bleeding and removing nebula.
Sea-buckthorn: relieve cough, dispel phlegm, promote digestion, remove food stagnation, activate blood and dissipate blood stasis. Can be used for treating cough with excessive phlegm, dyspepsia, abdominal pain due to dyspepsia, traumatic injury, blood stasis, swelling, and amenorrhea due to blood stasis.
Rhodiola root: cold, sweet and astringent, lung meridian, and has effects of invigorating qi, clearing lung-heat, improving intelligence, nourishing heart, astringing, stopping bleeding, removing blood stasis, and relieving swelling. Can be used for treating qi deficiency, asthenia, aversion to cold, short breath, asthenia, cough due to lung heat, hemoptysis, leucorrhea with diarrhea, and traumatic injury.
Radix aconiti: pungent, bitter and hot with strong toxicity. It enters heart, liver, kidney and spleen meridians. Dispel wind and dampness, warm meridians and alleviate pain.
Radix isatidis: entering heart and stomach meridians, has the effects of clearing away heat and toxic materials, cooling blood and relieving sore throat.
Gentiana flaccida: it has effects in expelling pathogenic wind and dampness, relieving deficiency heat, relieving pain, clearing away lung-heat, relieving cough, removing toxic materials, treating diseases, carbuncle and furuncle, and removing chest fire.
Corydalis edulis: clearing away heat and toxic material, relieving itching, astringing, arresting seminal emission, moistening lung, and relieving cough.
Morning glory seeds: purge water and relieve constipation, resolve phlegm and purge water, kill parasites and eliminate accumulation. Can be used for treating edema, constipation, phlegm accumulation, asthma, cough, abdominal pain, ascariasis, and taeniasis.
The invention also provides a method for preparing the Mongolian medicine composition pill for treating thyroid diseases, which comprises the following steps:
step one, processing, sterilizing and mixing antler, selfheal, scallop dust, sea buckthorn, rhodiola rosea, radix aconiti, radix isatidis, gentiana dabrya, corydalis edulis and pharbitis seed in sequence respectively, and crushing the mixture in a coarse crusher for 25-30 min to obtain coarse powder;
step two, putting the coarse powder obtained in the step one into a medicine crusher to be crushed for 25-30 min, then putting the crushed powder into a groove type mixer to be stirred for 3h, standing the mixture for 40min, and sieving the mixture by a sieve of 100 meshes to obtain medicine powder;
step three, scattering part of the medicinal powder a obtained in the step two into a sugar coating pot, uniformly spraying purified water a into the sugar coating pot, wetting the medicinal powder a through mechanical rotation or manual kneading, then performing mechanical rotation or manual kneading to obtain small particles, adding part of the medicinal powder b into the sugar coating pot again, uniformly spraying purified water b onto the small particles, wrapping the medicinal powder b on the outer sides of the small particles through mechanical rotation or manual kneading, repeating the operation to obtain large particles, and screening the large particles with uniform sizes to obtain large particle ball dies when the large particles are small grains;
step four, pouring the pill mold obtained in the step three into a sugar-coating pan, spraying purified water c to uniformly wet the pill mold, adding part of the medicinal powder c, wrapping the medicinal powder c on the outer side of the pill mold, repeatedly operating to obtain pills, and screening pills with the diameter of 5mm to obtain pills;
step five, drying the pills obtained in the step four at the temperature of 60 ℃, and turning over the tray for 1 time every 2 hours to obtain Mongolian medicine pills; the water content of the Mongolian medicine pill is 3-6%.
Preferably, the stirring speed of the trough mixer in the second step is 500 r/min-800 r/min.
Preferably, the rotating speed of the sugar coating pan in the second step and the third step is 250 r/min-300 r/min.
Preferably, the mass ratio of the medicinal powder a to the purified water a and the mass ratio of the medicinal powder b to the purified water b in the step three are 1: 2.
preferably, the mass ratio of the medicinal powder c to the purified water c in the fourth step is 1: 2.
compared with the prior art, the invention has the following advantages:
the Mongolian medicine composition for treating thyroid diseases is flat in physical property, is a good prescription for breaking stuffiness, mainly takes dry Hiriyasu, medicaments for drying pus and comprising antler, scallop tooth ash, selfheal, pharbitis seed and radix aconiti carmichaeli for removing blood stasis and diluting blood, is matched with sea buckthorn for relieving stasis and relieving swelling, and has rhodiola rosea, Damnacanthus kusnezoffii and isatis root for relieving fever and corydalis edulis for clearing heat and reducing swelling. The Mongolian medicine composition for treating thyroid diseases has no side effect and good curative effect.
The preparation method comprises the steps of processing, sterilizing, mixing, crushing, stirring and sieving the raw materials to obtain medicinal powder, spraying purified water and adding the medicinal powder one by one to prepare large granules, pouring the large granules into a sugar-coated pan after screening, spraying the purified water and adding the medicinal powder one by one to prepare pills, and drying the large granules after screening to obtain the Mongolian medicine pills.
Detailed Description
Example 1
The Mongolian medicine composition for treating thyroid diseases is prepared from the following raw materials in parts by weight: the feed is prepared from the following raw materials in parts by weight: 3 parts of antler, 2.4 parts of selfheal, 2.4 parts of scallop dust, 2.4 parts of sea-buckthorn, 2.4 parts of rhodiola root, 2.4 parts of monkshood, 2.4 parts of isatis root, 2.4 parts of gentiana damascena, 2.4 parts of corydalis tuber and 2.4 parts of pharbitis seed.
The present embodiment also provides a method of the above-described bolus of a Mongolian medicinal composition for treating thyroid disorders, comprising the steps of:
step one, processing, sterilizing and mixing antler, selfheal, scallop dust, sea buckthorn, rhodiola rosea, radix aconiti, radix isatidis, gentiana dabrya, corydalis edulis and pharbitis seed in sequence respectively, and crushing the mixture in a coarse crusher for 30min to obtain coarse powder;
step two, putting the coarse powder obtained in the step one into a medicine crusher to be crushed for 30min, then putting the crushed powder into a groove type mixer to be stirred for 3h, standing the mixture for 30min, and sieving the mixture by a sieve of 100 meshes to obtain medicine powder; the stirring speed of the groove type mixer is 800 r/min;
thirdly, scattering part of the medicine powder a obtained in the second step into a sugar coating pan with the rotating speed of 300r/min, uniformly spraying purified water a into the sugar coating pan, wetting the medicine powder a through mechanical rotation or manual kneading, then performing mechanical rotation or manual kneading to obtain small particles, adding part of the medicine powder b into the sugar coating pan again, uniformly spraying purified water b onto the small particles, wrapping the medicine powder b on the outer sides of the small particles through mechanical rotation or manual kneading, and repeating the operation to obtain large particles, and when the large particles are small grains, screening the large particles with uniform sizes to obtain a pill mold; the mass ratio of the medicinal powder a to the purified water a to the medicinal powder b to the purified water b is 1: 2;
step four, pouring the pill mold obtained in the step three into a sugar-coating pan with the rotating speed of 300r/min, spraying purified water c to uniformly wet the pill mold, adding part of the medicinal powder c, wrapping the medicinal powder c on the outer side of the pill mold, repeatedly operating to obtain pills, and screening pills with the diameter of 5mm to obtain the pills; the mass ratio of the medicinal powder c to the purified water c is 1: 2;
step five, drying the pills obtained in the step four at the temperature of 70 ℃, and turning over the tray for 1 time every 2 hours to obtain Mongolian medicine pills; the water content of the Mongolian medicine pill is 3%.
A certain patient, a woman, 35 years old, inner Mongolian herdsman, both past the history of thyroid gland hypofunction for 1 year, patient's plain laryngopharynx foreign body sensation, hypodynamia, the mood low, dry skin, symptom such as tinnitus see a doctor in our hospital and show through supplementary inspection: five items of first-effort: wherein TSH (thyroid stimulating hormone) 22.420 uIU/mL; TPOAb (antithyroid peroxidase antibody): 600IU/mL, and other indexes are normal; color of thyroid gland: diffuse lesions of the thyroid gland; physical examination: soft thyroid gland, tenderness, no smell of blood vessel noise, clear breathing sound of both lungs, no smell of dry and wet rales, normal heart, mild heart sound, heart rate of 78 times/min, flat and soft abdomen, no edema of both lower limbs, and pulse condition: deficiency, faint and weak, tongue: red tongue with white and thick coating; and (3) diagnosis: hypothyroidism; the medicament is taken as the treatment principles of disintegrating masses, removing stasis, clearing heat and the like: the Mongolian medicine composition pill for treating thyroid diseases prepared by the embodiment is taken with 3g of boiled water 30min after meals; and (2) evening: the mongolian medicine composition pill for treating thyroid diseases, prepared in the embodiment, is taken 30min after 3g of meals, the foreign body sensation, the hypodynamia, the low mood and other symptoms of the throat of a patient are obviously improved after 3 months of oral medicine treatment, and five items of Jiagong are rechecked: TSH (thyroid stimulating hormone): 13.380uIU/mL, and other indexes are normal.
A certain patient, a woman, a 44-year-old patient, inner Mongolian herdsmen, the past thyroid nodule disease history is 1 year, the patient is calm, feels foreign body sensation in throat, and symptoms such as irritability, hyperhidrosis, abdominal distension, facial edema, hypodynamia and the like go to the hospital and are shown through auxiliary examination: color of thyroid gland: diffuse lesions of the thyroid gland; thyroid right lobe solid nodules-close observations are suggested; physical examination: soft thyroid gland, tenderness, no smell of blood vessel noise, clear respiratory sound of both lungs, no smell of dry and wet rales, normal heart, good heart sound, heart rate of 80 times/min, flat and soft abdomen, no edema of both lower limbs, and pulse condition: number, chord and tight, tongue: red tongue with yellow coating; and (3) diagnosis: thyroid nodule; the medicament is taken as the treatment principles of disintegrating masses, removing stasis, clearing heat and the like: 3g of the Mongolian medicine composition pill for treating thyroid diseases prepared by the embodiment is taken with boiled water 30min after meals; and (2) evening: the mongolian medicine composition pill for treating thyroid diseases prepared in the embodiment is taken with boiled water 30min after 3g of meals, symptoms such as foreign body sensation of throat, facial edema, hypodynamia and the like of a patient are obviously improved after 20 days of oral medicine treatment, and thyroid color ultrasonography is reviewed: diffuse thyroid lesion without obvious nodules.
The Mongolian medicine composition for treating thyroid diseases has flat physical properties, is a good prescription for breaking stuffiness, mainly takes dry Hiriyasu, drugs for drying pus and blood, namely antler, scallop tooth ash, selfheal, pharbitis seed and radix aconiti carmichaeli, and a drug for killing stickiness, is matched with sea buckthorn for removing stasis and diluting blood, and takes rhodiola rosea, Gentiana flaccida and isatis root for relieving fever, and corydalis edulis for clearing heat and relieving swelling. The Mongolian medicine composition for treating thyroid diseases has the advantages of no side effect and good curative effect.
The preparation method comprises the steps of processing, sterilizing, mixing, crushing, stirring and sieving the raw materials to obtain medicinal powder, spraying purified water and adding the medicinal powder one by one to prepare large granules, pouring the large granules into a sugar-coated pan after screening, spraying the purified water and adding the medicinal powder one by one to prepare pills, and drying the large granules after screening to obtain the Mongolian medicine pills.
The above description is only for the preferred embodiment of the present invention, and is not intended to limit the present invention in any way. Any simple modification, change and equivalent changes of the above embodiments according to the technical essence of the invention are still within the protection scope of the technical solution of the invention.
Claims (2)
1. A Mongolian medicine composition for treating hypothyroidism and thyroid nodules is characterized by being prepared from the following raw materials in parts by weight: 3 parts of antler, 2.4 parts of selfheal, 2.4 parts of scallop dust, 2.4 parts of sea-buckthorn, 2.4 parts of rhodiola root, 2.4 parts of monkshood, 2.4 parts of isatis root, 2.4 parts of gentiana damascena, 2.4 parts of corydalis tuber and 2.4 parts of pharbitis seed.
2. A method of preparing a bolus of a Mongolian medicinal composition for the treatment of hypothyroidism and thyroid nodules according to claim 1, comprising the steps of:
step one, processing, sterilizing and mixing antler, selfheal, scallop dust, sea buckthorn, rhodiola rosea, radix aconiti, radix isatidis, gentiana dabrya, corydalis edulis and pharbitis seed in sequence respectively, and crushing the mixture in a coarse crusher for 30min to obtain coarse powder;
step two, putting the coarse powder obtained in the step one into a medicine crusher to be crushed for 30min, then putting the crushed powder into a groove type mixer to be stirred for 3h, standing the mixture for 30min, and sieving the mixture by a sieve of 100 meshes to obtain medicine powder; the stirring speed of the groove type mixer is 800 r/min;
thirdly, scattering part of the medicine powder a obtained in the second step into a sugar coating pan with the rotating speed of 300r/min, uniformly spraying purified water a into the sugar coating pan, wetting the medicine powder a through mechanical rotation or manual kneading, then performing mechanical rotation or manual kneading to obtain small particles, adding part of the medicine powder b into the sugar coating pan again, uniformly spraying purified water b onto the small particles, wrapping the medicine powder b on the outer sides of the small particles through mechanical rotation or manual kneading, and repeating the operation to obtain large particles, and when the large particles are small grains, screening the large particles with uniform sizes to obtain a pill mold; the mass ratio of the medicinal powder a to the purified water a to the medicinal powder b to the purified water b is 1: 2;
step four, pouring the pill mold obtained in the step three into a sugar-coating pan with the rotating speed of 300r/min, spraying purified water c to uniformly wet the pill mold, adding part of the medicinal powder c, wrapping the medicinal powder c on the outer side of the pill mold, repeatedly operating to obtain pills, and screening pills with the diameter of 5mm to obtain the pills; the mass ratio of the medicinal powder c to the purified water c is 1: 2;
step five, drying the pills obtained in the step four at the temperature of 70 ℃, and turning over the tray for 1 time every 2 hours to obtain Mongolian medicine pills; the water content of the Mongolian medicine pill is 3%.
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CN101007085A (en) * | 2006-11-16 | 2007-08-01 | 内蒙古复旦蒙耀生物技术有限责任公司 | A drug for treating hyperthyroidism and its preparation method |
CN104510892A (en) * | 2014-12-23 | 2015-04-15 | 青岛市城阳区人民医院 | Traditional Chinese medicinal formula for treating thyroid tumor |
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CN101007085A (en) * | 2006-11-16 | 2007-08-01 | 内蒙古复旦蒙耀生物技术有限责任公司 | A drug for treating hyperthyroidism and its preparation method |
CN104510892A (en) * | 2014-12-23 | 2015-04-15 | 青岛市城阳区人民医院 | Traditional Chinese medicinal formula for treating thyroid tumor |
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