CN101361912B - Plaster for treating burn and preparation method thereof - Google Patents

Plaster for treating burn and preparation method thereof Download PDF

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Publication number
CN101361912B
CN101361912B CN2008101410671A CN200810141067A CN101361912B CN 101361912 B CN101361912 B CN 101361912B CN 2008101410671 A CN2008101410671 A CN 2008101410671A CN 200810141067 A CN200810141067 A CN 200810141067A CN 101361912 B CN101361912 B CN 101361912B
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radix
plaster
rhizoma
burn
days
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CN101361912A (en
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张国忠
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Abstract

The invention relates to the field of Chinese medicine preparation, in particular to a plaster used for treating burn injury and a preparation method thereof. The plaster comprises bulk pharmaceuticals and excipients, wherein, the bulk pharmaceuticals include the following ingredients: Rhubarb, Phellodendron Chinese Schneid, Ampelopsis Japonica, Ciliatenerve Knotweed Root, Gypsum, Atractylodes, Angelica dahurica Benth. et Hook, Garden Burnet, Radix Rehmanniae, Sediment of human urine, mirabilite, Bletilla, Tortoise Shell, Ground Beetle, draconis sanguis, Chinese Angelica, Diverse Wormwood Herb, Asarum, NidusVespae, Venenum Bufonis, Calomel, Poppy, Glycyrrhiza, Pearl, musk and catechu. The plaster has a short curable duration which lasts 3 days to 20 days and the average duration 12 days. No scar is left after cure and pigmentation is little.

Description

Plaster of treatment burn and preparation method thereof
(1) technical field
The present invention relates to field of traditional Chinese, particularly plaster of treatment burn and preparation method thereof.
(2) background technology
Burn also claims to scald, and is the tissue injury that is caused by high temperature, chemical substance or electricity.The degree of burn is by the height of temperature, the length of action time and difference.Partial variation can be divided into four degree.First degree: because of angioparalysis hyperemia.Second degree: form the burn vesicle that is full of serum.The 3rd degree: tissue necrosis.Fourth: the carbonization of tissue.Lactic acid production during burn in the visible blood increases, and the pH value of arteriovenous blood reduces, along with organizing the handicapped anoxemia (anoxemia) that increases the weight of of blood capillary also to increase weight.Clinical experience proves, burn reaches 1/3rd of total body surface area and then can be in peril of one's life when above.The order of severity of burn depends on the scope and the degree of depth of wounded tissue, and depth of burn can be divided into I degree, II degree and III degree.I degree burn injury is the lightest.Burned skin is rubescent, pain, obviously touch a tender spot, have and ooze out or edema.The part bleaches during light pressure injury, but does not have vesicle.II degree burn injury is darker, skin blister, and the vesicle bottom takes on a red color or white, has been full of limpid, heavy-gravity liquid.It is responsive to touch a tender spot, and bleaches during compressing.III degree burn injury is the darkest, and burn surfaces can turn white, deliquescing or be black, carbonization hide-like.Become pale owing to burn skin, in the pale skin people, often be mistaken as normal skin, but no longer variable color during compressing.Destructive erythrocyte can make the burn local skin be cerise, and vesicle is arranged once in a while, and the hair in burn district is easy to extract, and feels to go down.III degree burn area does not generally have the pain sensation.Because the teleneuron of skin is destroyed.
At present the outer treating method of treatment burn comprises the skin ulcer face that cleans, and blister is handled, and removes eschar or skin-grafting etc., and the medicine that is used for the treatment of burn is also varied, and shortening healing period and reducing cicatrix that burn stays then is constantly to be devoted to the problem that solves.
(3) summary of the invention
The object of the present invention is to provide a kind of plaster for the treatment of burn, healing period is short, and therapeutic effect is good.
The technical solution used in the present invention is as follows:
The plaster of treatment burn, comprise crude drug and adjuvant, wherein crude drug comprises following parts by weight of component: Radix Et Rhizoma Rhei 25-80 Cortex Phellodendri 75-240 Radix Ampelopsis 25-80 Radix Polygoni Ciliinerve 100-280 Gypsum Fibrosum 25-80 Rhizoma Atractylodis 25-80 Radix Angelicae Dahuricae 25-80 Radix Sanguisorbae 25-80 Radix Rehmanniae 75-240 calamitas urinae hominis 15-48 Natrii Sulfas 25-80 Pseudobulbus Bletillae (Rhizoma Bletillae) 25-80 moxibustion Carapax et Plastrum Testudinis 50-160 eupolyphaga 5-16 Sanguis Draxonis 8-26 Radix Angelicae Sinensis 150-320 Herba Artemisiae Anomalae 25-80 Herba Asari 10-32 Nidus Vespae 25-80 Venenum Bufonis 8-20 Calomelas 8-26 Semen Papaveris 38-120 Radix Glycyrrhizae 25-80 Margarita 4-15 Moschus 5-16 catechu 20-64.
Further, above composition weight is composed as follows:
Radix Et Rhizoma Rhei 40-60 Cortex Phellodendri 100-180 Radix Ampelopsis 40-60 Radix Polygoni Ciliinerve 150-230 Gypsum Fibrosum 40-60 Rhizoma Atractylodis 40-60 Radix Angelicae Dahuricae 40-60 Radix Sanguisorbae 40-60 Radix Rehmanniae 100-180 calamitas urinae hominis 20-38 Natrii Sulfas 40-60 Pseudobulbus Bletillae (Rhizoma Bletillae) 40-60 moxibustion Carapax et Plastrum Testudinis 80-130 eupolyphaga 8-13 Sanguis Draxonis 10-22 Radix Angelicae Sinensis 200-280 Herba Artemisiae Anomalae 40-60 Herba Asari 15-25 Nidus Vespae 40-60 Venenum Bufonis 10-22 Calomelas 10-22 Semen Papaveris 55-90 Radix Glycyrrhizae 40-60 Margarita 6-12 Moschus 8-13 catechu 30-55.
Described adjuvant comprises wax of 200-300 part and the Oleum sesami of 5000-6500 part.
The preparation of the plaster of described treatment burn can followingly be carried out: proportionally get each crude drug, mix after making powder respectively, again with the Oleum sesami of wax that is heated to fusing and 5000-6500 weight portion mixed described plaster, the parts by weight of wax are 200-300 part.
In the crude drug, Radix Et Rhizoma Rhei removes stagnation of pathogenic heat and weeds out the old and bring forth the new the Cortex Phellodendri heat clearing and damp drying, Radix Polygoni Ciliinerve, Radix Ampelopsis heat-clearing and toxic substances removing, pain relieving granulation promoting, the hot pain relieving removing dampness of Gypsum Fibrosum expelling pathogenic factors from muscles is put on flesh, and the Rhizoma Atractylodis damp eliminating is swollen, the evacuation of pus of Radix Angelicae Dahuricae dampness reducing swelling and alleviating pain, Radix Sanguisorbae heat-clearing and toxic substances removing, cooling blood and relieving pain, evacuation of pus putrefaction removing, the Radix Rehmanniae nourishing YIN and benefiting blood is put on flesh, Pseudobulbus Bletillae (Rhizoma Bletillae), calamitas urinae hominis, the heat clearing away of moxibustion Carapax et Plastrum Testudinis, blood stasis dispelling are put on flesh, Natrii Sulfas reducing swelling and alleviating pain, the eupolyphaga removing blood stasis reuniting the fractured tendons and bones of putting on flesh, draws pus and puts on flesh at the pain relieving of Sanguis Draxonis removing blood stasis, the Radix Angelicae Sinensis removing blood stasis is burst hard, and pain relieving is put on flesh; Skin ulcer is held back in the detumescence of Herba Artemisiae Anomalae removing blood stasis; Herba Asari dispel skin pruritus pain, slough, dead flesh; Nidus Vespae merit poison, parasite killing, pain relieving, antiallergic; The Venenum Bufonis anti-inflammation detumescence; The Margarita removing toxic substances and promoting granulation, Calomelas counteracting toxic substances detumescence putrefaction removing and tissue regeneration promoting, the pain relieving of Semen Papaveris removing dampness; Catechu heat clearing away removing dampness pain relieving granulation promoting, Radix Glycyrrhizae detoxifcation transfer the hard bone of medicine to put on flesh the sensible awake flesh of Moschus.Wherein Carapax Et Plastrum Testudinis (processed) has another name called the vinegar Carapax et Plastrum Testudinis, for clean Carapax et Plastrum Testudinis sheet sand parching to brown, immerses while hot in the vinegar, and with drying the person of being used as medicine after the flushing with clean water, the YIN nourishing effect strengthens.
This plaster is suitable for I-III degree burn, I-II degree below 50% wherein, small size III degree.
Usage is as follows:
Carry out treatment of wounds earlier, specific as follows: with the sterilization of 1% polyethylene pyrroles iodine, normal saline flushing is used in the flushing of 3% hydrogen peroxide to the III degree then earlier, and aseptic yarn cotton is dried; The II degree is with povidone iodine or 7% ethanol disinfection, hydrogen peroxide, normal saline flushing; Blister: break the tapping of bubble skin, aseptic powder is dried.The back is coated with this ointment, once a day, only needs when changing dressings to scrape off old medicine with the sterilization spatula, is coated with new drug.The I degree only needs to get final product at the direct smearing ointment in erythema place, 1-2 recovery from illness.
Pain relieving is rapid behind the coating, do not have rigid incrustation, is the wettability ointment, purulent secretion and slough directly are dissolved in the medicinal liquid, and the wound surface and the external world separate, and reduce loss of water in the body, granulation tissue is quick hypertrophy under medicinal liquid stimulates, and dressing change frequency according to circumstances can suitably increase and decrease.Basically shallow II degree about 5 days more, dark II degree 5-10 days more, III degree 10-20 days more, the no scar in back more, pigmentation do not have or gently.
The present invention has following advantage with respect to prior art:
Plaster healing period of the present invention is short, is 3-20 days, and average needs 12 days.More no scar after, pigmentation also seldom.
(4) specific embodiment:
Below with specific embodiment technical scheme of the present invention is described, but protection scope of the present invention is not limited thereto:
Embodiment 1
Raw material is composed as follows, the g of unit:
Radix Et Rhizoma Rhei 25 Cortex Phellodendris 75 Radix Ampelopsis 25 Radix Polygoni Ciliinerves 100 Gypsum Fibrosum 25 Rhizoma Atractylodis 25 Radixs Angelicae Dahuricae 25 Radix Sanguisorbaes 25 Radix Rehmanniae 75 calamitas urinae hominises 15 Natrii Sulfas 25 Pseudobulbus Bletillae (Rhizoma Bletillae) 25 moxibustion Carapax et Plastrum Testudiniss 50 eupolyphaga 5 Sanguis Draxonis 8 Radix Angelicae Sinensis 150 Herba Artemisiae Anomalaes 25 Herba Asaris 10 Nidus Vespae 25 Venenum Bufoniss 8 Calomelass 8 Semen Papaveriies 38 Radix Glycyrrhizaes 25 Margaritas 4 Moschus 5 catechu 20.With above each crude drug grind into powder and mix, then with the Oleum sesami of 200g wax that is heated to fusing and 5000g mixed described plaster.
Embodiment 2
Radix Et Rhizoma Rhei 30g Cortex Phellodendri 80g Radix Ampelopsis 30g Radix Polygoni Ciliinerve 120g Gypsum Fibrosum 30g Rhizoma Atractylodis 30g Radix Angelicae Dahuricae 30g Radix Sanguisorbae 30g Radix Rehmanniae 80g calamitas urinae hominis 20g Natrii Sulfas 30g Pseudobulbus Bletillae (Rhizoma Bletillae) 30g moxibustion Carapax et Plastrum Testudinis 60g eupolyphaga 6g Sanguis Draxonis 10g Radix Angelicae Sinensis 180g Herba Artemisiae Anomalae 30g Herba Asari 15g Nidus Vespae 30g Venenum Bufonis 10g Calomelas 10g Semen Papaveris 45g Radix Glycyrrhizae 30g Margarita 5g Moschus 7g catechu 25g.
With each crude drug grind into powder and mix, then with the Oleum sesami of 220g wax that is heated to fusing and 5200g mixed described plaster.
Embodiment 3
Raw material is composed as follows, the g of unit:
Radix Et Rhizoma Rhei 40 Cortex Phellodendris 100 Radix Ampelopsis 40 Radix Polygoni Ciliinerves 150 Gypsum Fibrosum 40 Rhizoma Atractylodis 40 Radixs Angelicae Dahuricae 40 Radix Sanguisorbaes 40 Radix Rehmanniae 100 calamitas urinae hominises 20 Natrii Sulfas 40 Pseudobulbus Bletillae (Rhizoma Bletillae) 40 moxibustion Carapax et Plastrum Testudiniss 80 eupolyphaga 8 Sanguis Draxonis 10 Radix Angelicae Sinensis 200 Herba Artemisiae Anomalaes 40 Herba Asaris 15 Nidus Vespae 40 Venenum Bufoniss 10 Calomelass 10 Semen Papaveriies 55 Radix Glycyrrhizaes 40 Margaritas 6 Moschus 8 catechu 30.With above each crude drug grind into powder and mix, then with the Oleum sesami of 230g wax that is heated to fusing and 5400g mixed described plaster.
Embodiment 4
Radix Et Rhizoma Rhei 45g Cortex Phellodendri 160g Radix Ampelopsis 45g Radix Polygoni Ciliinerve 180 Gypsum Fibrosum 45g Rhizoma Atractylodis 45g Radix Angelicae Dahuricae 45g Radix Sanguisorbae 45g Radix Rehmanniae 130g calamitas urinae hominis 25g Natrii Sulfas 45g Pseudobulbus Bletillae (Rhizoma Bletillae) 45g moxibustion Carapax et Plastrum Testudinis 80g eupolyphaga 8g Sanguis Draxonis 13g Radix Angelicae Sinensis 200g Herba Artemisiae Anomalae 45g Herba Asari 18g Nidus Vespae 45g Venenum Bufonis 13g Calomelas 14g Semen Papaveris 65g Radix Glycyrrhizae 45g Margarita 7g Moschus 8g catechu 35g.
With above each crude drug grind into powder and mix, then with the Oleum sesami of 250g wax that is heated to fusing and 5700g mixed described plaster.
Embodiment 5
Radix Et Rhizoma Rhei 50g Cortex Phellodendri 150g Radix Ampelopsis 50g Radix Polygoni Ciliinerve 200g Gypsum Fibrosum 50g Rhizoma Atractylodis 50g Radix Angelicae Dahuricae 50g Radix Sanguisorbae 50g Radix Rehmanniae 150g calamitas urinae hominis 30g Natrii Sulfas 50g Pseudobulbus Bletillae (Rhizoma Bletillae) 50g moxibustion Carapax et Plastrum Testudinis 100g eupolyphaga 10g Sanguis Draxonis 16g Radix Angelicae Sinensis 250g Herba Artemisiae Anomalae 50g Herba Asari 20g Nidus Vespae 50g Venenum Bufonis 16g Calomelas 16g Semen Papaveris 75g Radix Glycyrrhizae 50g Margarita 9g Moschus 10g catechu 40g.
With above each crude drug grind into powder and mix, then with the Oleum sesami of 260g wax that is heated to fusing and 5800g mixed described plaster.
Embodiment 6
Radix Et Rhizoma Rhei 60 Cortex Phellodendris 180 Radix Ampelopsis 60 Radix Polygoni Ciliinerves 230 Gypsum Fibrosum 60 Rhizoma Atractylodis 60 Radixs Angelicae Dahuricae 60 Radix Sanguisorbaes 60 Radix Rehmanniae 180 calamitas urinae hominises 38 Natrii Sulfas 60 Pseudobulbus Bletillae (Rhizoma Bletillae) 60 moxibustion Carapax et Plastrum Testudiniss 130 eupolyphaga 13 Sanguis Draxonis 22 Radix Angelicae Sinensis 280 Herba Artemisiae Anomalaes 60 Herba Asaris 25 Nidus Vespae 60 Venenum Bufoniss 22 Calomelass 22 Semen Papaveriies 90 Radix Glycyrrhizaes 60 Margaritas 12 Moschus 13 catechu 55.
With above each crude drug grind into powder and mix, then with the Oleum sesami of 270g wax that is heated to fusing and 6000g mixed described plaster.
Embodiment 7
Radix Et Rhizoma Rhei 70g Cortex Phellodendri 220g Radix Ampelopsis 70g Radix Polygoni Ciliinerve 250g Gypsum Fibrosum 70g Rhizoma Atractylodis 70g Radix Angelicae Dahuricae 70g Radix Sanguisorbae 70g Radix Rehmanniae 210g calamitas urinae hominis 40g Natrii Sulfas 70g Pseudobulbus Bletillae (Rhizoma Bletillae) 70g moxibustion Carapax et Plastrum Testudinis 140g eupolyphaga 14g Sanguis Draxonis 22g Radix Angelicae Sinensis 300g Herba Artemisiae Anomalae 70g Herba Asari 28g Nidus Vespae 70g Venenum Bufonis 20g Calomelas 22g Semen Papaveris 100g Radix Glycyrrhizae 70g Margarita 13g Moschus 14g catechu 55g.
With above each crude drug grind into powder and mix, then with the Oleum sesami of 280g wax that is heated to fusing and 6250g mixed described plaster.
Embodiment 8
Raw material is composed as follows, the g of unit:
Radix Et Rhizoma Rhei 80 Cortex Phellodendris 240 Radix Ampelopsis 80 Radix Polygoni Ciliinerves 280 Gypsum Fibrosum 80 Rhizoma Atractylodis 80 Radixs Angelicae Dahuricae 80 Radix Sanguisorbaes 80 Radix Rehmanniae 240 calamitas urinae hominises 48 Natrii Sulfas 80 Pseudobulbus Bletillae (Rhizoma Bletillae) 80 moxibustion Carapax et Plastrum Testudiniss 160 eupolyphaga 16 Sanguis Draxonis 26 Radix Angelicae Sinensis 320 Herba Artemisiae Anomalaes 80 Herba Asaris 32 Nidus Vespae 80 Venenum Bufoniss 25 Calomelass 26 Semen Papaveriies 120 Radix Glycyrrhizaes 80 Margaritas 15 Moschus 16 catechu 64.
With above each crude drug grind into powder and mix, then with the Oleum sesami of 300g wax that is heated to fusing and 6500g mixed described plaster.
Model case:
1. Zhang, the man, two years old, hot meal was scalded chest, is shallow II degree, every day coating once, five days are more.
2. Lee, 58 years old, the head electric injury, the III degree, wound one yuan size, 20 days are more.
3. Wang, the woman, 20 years old, facial chemical injury referred to the big open sore part, and refractory more uses this ointment for a long time, and three times are more.

Claims (4)

1. the plaster of treatment burn comprises crude drug and adjuvant, it is characterized in that crude drug is made up of following parts by weight of component:
Radix Et Rhizoma Rhei 25-80 Cortex Phellodendri 75-240 Radix Ampelopsis 25-80 Radix Polygoni Ciliinerve 100-280 Gypsum Fibrosum 25-80 Rhizoma Atractylodis 25-80 Radix Angelicae Dahuricae 25-80 Radix Sanguisorbae 25-80 Radix Rehmanniae 75-240 calamitas urinae hominis 15-48 Natrii Sulfas 25-80 Pseudobulbus Bletillae (Rhizoma Bletillae) 25-80 moxibustion Carapax et Plastrum Testudinis 50-160 eupolyphaga 5-16 Sanguis Draxonis 8-26 Radix Angelicae Sinensis 150-320 Herba Artemisiae Anomalae 25-80 Herba Asari 10-32 Nidus Vespae 25-80 Venenum Bufonis 8-25 Calomelas 8-26 Semen Papaveris 38-120 Radix Glycyrrhizae 25-80 Margarita 4-15 Moschus 5-16 catechu 20-64.
2. the plaster of treatment burn as claimed in claim 1 is characterized in that described composition weight is composed as follows:
Radix Et Rhizoma Rhei 40-60 Cortex Phellodendri 100-180 Radix Ampelopsis 40-60 Radix Polygoni Ciliinerve 150-230 Gypsum Fibrosum 40-60 Rhizoma Atractylodis 40-60 Radix Angelicae Dahuricae 40-60 Radix Sanguisorbae 40-60 Radix Rehmanniae 100-180 calamitas urinae hominis 20-38 Natrii Sulfas 40-60 Pseudobulbus Bletillae (Rhizoma Bletillae) 40-60 moxibustion Carapax et Plastrum Testudinis 80-130 eupolyphaga 8-13 Sanguis Draxonis 10-22 Radix Angelicae Sinensis 200-280 Herba Artemisiae Anomalae 40-60 Herba Asari 15-25 Nidus Vespae 40-60 Venenum Bufonis 10-22 Calomelas 10-22 Semen Papaveris 55-90 Radix Glycyrrhizae 40-60 Margarita 6-12 Moschus 8-13 catechu 30-55.
3. the plaster of treatment burn as claimed in claim 1 or 2 is characterized in that adjuvant comprises wax of 200-300 part and the Oleum sesami of 5000-6500 part.
4. method for preparing the plaster of claim 1 or 2 described treatments burn, it is characterized in that proportionally getting each crude drug, mix after making powder respectively, again with the Oleum sesami of wax that is heated to fusing and 5000-6500 weight portion mixed described plaster, the parts by weight of wax are 200-300 part.
CN2008101410671A 2008-08-18 2008-08-18 Plaster for treating burn and preparation method thereof Expired - Fee Related CN101361912B (en)

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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101926911B (en) * 2010-09-03 2011-11-16 杜江 Chinese medicinal composition for relieving pain and preparation method thereof
CN102284011A (en) * 2011-07-29 2011-12-21 尉文胜 Chinese medicinal ointment for treating burn
CN103341036B (en) * 2013-07-11 2014-11-26 徐计锁 External medicine for treating burn
CN103599291B (en) * 2013-11-20 2016-05-25 于田 A kind of ointment for the treatment of burn and scald
CN104383313B (en) * 2014-10-28 2018-01-16 泉州救生源康美生物科技有限公司 A kind of pharmaceutical composition for treating burning/scald
CN104491442B (en) * 2014-12-26 2018-02-02 刘玉柱 A kind of preparation technology for treating injury from electricity pharmaceutical composition
CN105232849A (en) * 2015-11-09 2016-01-13 李承存 Plaster for treating burns
CN105596508A (en) * 2016-01-27 2016-05-25 张银贵 External application medicine powder for treating burns

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Publication number Priority date Publication date Assignee Title
CN1174723A (en) * 1997-08-21 1998-03-04 王中岳 External used traditional Chinese medicine for curing burn and injury
CN1256138A (en) * 1999-08-17 2000-06-14 王占一 Pain-relieving and inflammation-diminishing medicine powder for burn and scald
CN1498628A (en) * 2002-11-05 2004-05-26 潘福宽 External burn cream
CN1864732A (en) * 2005-05-21 2006-11-22 李怡初 An ointment for treating scalds and burns
CN1966001A (en) * 2006-11-13 2007-05-23 北京和为康医药科技有限公司 Medicament for treating inflammation and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1174723A (en) * 1997-08-21 1998-03-04 王中岳 External used traditional Chinese medicine for curing burn and injury
CN1256138A (en) * 1999-08-17 2000-06-14 王占一 Pain-relieving and inflammation-diminishing medicine powder for burn and scald
CN1498628A (en) * 2002-11-05 2004-05-26 潘福宽 External burn cream
CN1864732A (en) * 2005-05-21 2006-11-22 李怡初 An ointment for treating scalds and burns
CN1966001A (en) * 2006-11-13 2007-05-23 北京和为康医药科技有限公司 Medicament for treating inflammation and preparation method thereof

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