CN104055922A - Traditional Chinese medicinal preparation for treating pressure sores and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicinal preparation for treating pressure sores, as well as a preparation method of the traditional Chinese medicinal preparation. The preparation method comprises the following steps: weighing Chinese angelica, lonicera japonica, raw rehmmania, liquorice, lithospermum, albizia julibrissin, frankincense, myrrh, astragalus membranaceus, cinnamon, safflower, asarum, pearl powder, halloysitum rubrum, fossil fragment, woodlouse, radix scrophulariae, red peony root, teasel root, ligusticum wallichii and dried tangerine peel, washing, and removing impurities; airing, crushing, and grinding into powder of 100-150 meshes; respectively washing, removing impurities, airing, crushing and grinding into powder of 100-150 meshes, and uniformly mixing. The traditional Chinese medicinal preparation is prepared from natural traditional Chinese medicinal raw materials, accords with the principle of prescription medication of traditional Chinese medicine, is easy and convenient to prepare, wide in medicinal source, low in cost, remarkable in curative effect, reliable in effect and mild in drug property, and does not have toxic or side effect. Clinical application proves that the effective rate of the traditional Chinese medicinal preparation on bedsores caused by damp-heat toxic-stasis obstruction, qi deficiency and no tissue generation is over 90 percent.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of pressure ulcer

Technical field

The present invention discloses a kind of Chinese medicine preparation for the treatment of pressure ulcer, and the preparation method of this Chinese medicine preparation is also provided simultaneously, belongs to traditional Chinese medical science pharmaceutical technology field.

Background technology

Pressure ulcer is local organization continuous compression, causes disturbance of blood circulation, and histotrophic nutrition lacks disorganization and the necrosis that causes skin to lose normal function and cause.Be apt to occur in and lack fatty tissue protection or thinner bone knuckle place and the pressurized position of flesh layer, as scapula, sacrococcygeal region, hip etc.Pressure ulcer is clinical common complication.The Western medicine of topical therapeutic pressure ulcer is at present more, and primary treatment principle is that infection is main, strengthens local organization nutrition, promotes that tissue growth is auxiliary.So before using antibiotic, antibacterial culturing and the drug sensitivity test that should do secretions with good conditionsi.The method expense of traditional treatment pressure ulcer is high, and curative effect is slow, and the generation that has side effect having causes burden and painful to patient.

Summary of the invention

The invention provides a kind of Chinese medicine preparation for the treatment of pressure ulcer, use pharmacology and the drug effect of Chinese medicine, reach determined curative effect obviously, have no side effect.

A kind of Chinese medicine preparation preparation method for the treatment of pressure ulcer provided by the invention, is applicable to suitability for industrialized production.

The invention provides a kind of Chinese medicine preparation for the treatment of pressure ulcer, mainly by following raw materials by weight portion than making:

Radix Angelicae Sinensis 45 ~ 50, Flos Lonicerae 35 ~ 40, Radix Rehmanniae 30 ~ 40, Radix Glycyrrhizae 30 ~ 40, Radix Arnebiae (Radix Lithospermi) 43 ~ 50, Herba Albiziae 8 ~ 15, Olibanum 10 ~ 15, Myrrha 10 ~ 15, the Radix Astragali 55 ~ 65, Cortex Cinnamomi 55 ~ 65, Flos Carthami 25 ~ 35, Herba Asari 10 ~ 20, Margarita powder 8 ~ 13, Halloysitum Rubrum 8 ~ 15, Os Draconis 5 ~ 15, ground beetle 2 ~ 6, Radix Scrophulariae 5 ~ 15, Radix Paeoniae Rubra 8 ~ 12, Radix Dipsaci 8 ~ 12, Rhizoma Chuanxiong 10 ~ 20, Pericarpium Citri Reticulatae 5 ~ 15.

The Chinese medicine preparation for the treatment of pressure ulcer provided by the invention, optimum ratio is:

Radix Angelicae Sinensis 48, Flos Lonicerae 36, Radix Rehmanniae 36, Radix Glycyrrhizae 36, Radix Arnebiae (Radix Lithospermi) 48, Herba Albiziae 12, Olibanum 12, Myrrha 12, the Radix Astragali 60, Cortex Cinnamomi 60, Flos Carthami 30, Herba Asari 15, Margarita powder 10, Halloysitum Rubrum 10, Os Draconis 10, ground beetle 5, Radix Scrophulariae 10, Radix Paeoniae Rubra 10, Radix Dipsaci 10, Rhizoma Chuanxiong 15, Pericarpium Citri Reticulatae 10.

The preparation technology of Chinese medicine preparation that the present invention treats pressure ulcer is as follows:

Get above-mentioned raw materials and clean roguing, dry, pulverize, grind into powder 100 order ~ 150 orders, clean respectively roguing, dry, and pulverize grind into powder 100 order ~ 150 orders, mix homogeneously and get final product.

[usage and dosage]3 times/day; 5 ~ 10g/ time; During use, medicated powder is directly spread on skin ulcer face, then covers kpetrolatum gauze.

[indication]the I degree pressure ulcer that various factors causes and light degree Ⅱ pressure ulcer.

[side separate] damp and hot malicious stasis of blood of primary treatment of the present invention is tied mutually, and the deficiency of vital energy is the decubital ulcer of granulation promoting not for a long time.

Flos Lonicerae is sweet cold, heat-clearing and toxic substances removing, and dispelling wind and heat pathogens is monarch drug; Radix Angelicae Sinensis Gan Xinwen, enriches blood and invigorates blood circulation, menstruction regulating and pain relieving; Radix Arnebiae (Radix Lithospermi) is sweet cold, removing heat from blood and promoting blood circulation, removing toxic substances; Olibanum, the pain relieving of Myrrha blood-activating and qi-promoting, detumescence and promoting granulation; The pungent temperature of Flos Carthami, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing; The pungent temperature of Rhizoma Chuanxiong, blood-activating and qi-promoting, wind-expelling pain-stopping; Eupolyphaga Seu Steleophaga is salty-cold, removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones; Radix Rehmanniae sweetness and bitterness is cold, clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Radix Scrophulariae, Radix Paeoniae Rubra are salty-cold, clearing away heat and cooling blood, detoxicating and resolving stagnation of pathogens, eliminating stasis to stop pain; Cortex Albiziae is sweet flat, promoting blood circulation and detumescence; The pungent temperature of Pericarpium Citri Reticulatae, the dampness of regulating the flow of vital energy; Cortex Cinnamomi Xin Ganre, mends fire supporing yang, dispersing cold for relieving pain, warming the meridian and promoting blood circulation; Above 13 herbal medicines are played blood-activating and qi-promoting pain relieving altogether, and the effect that removing toxic substances dissipating blood stasis stimulates the menstrual flow, is ministerial drug altogether; Margarita powder, Os Draconis, Halloysitum Rubrum three restrain astringent or styptic treatment for spontaneous sweating, expelling pus and promoting granulation; Radix Dipsaci is arduous, and hemostasis is cured the wound and continued folding; The sweet temperature of the Radix Astragali, QI invigorating benefit is defended consolidating superficial resistance, inducing diuresis to remove edema, holder skin ulcer granulation promoting; The pungent temperature of Herba Asari, expelling wind and cold, understand things pain-stopping, above six medicine assistants are controlled ministerial drug and are played QI invigorating expelling pus and promoting granulation, and the merit that hemostasia and detumescence is cured the wound, is adjuvant drug altogether; Radix Glycyrrhizae is sweet flat, QI invigorating invigorating middle warmer, and heat-clearing and toxic substances removing, relieving spasm to stop pain, the coordinating the actions of various ingredients in a prescription property of medicine, and for making medicine.

the curative effect that shows medicine of the present invention by following clinical trial:

Clinical patients 30 examples, I degree pressure ulcer person 10 examples wherein, medication is after 3 days, and effective 3 examples, cure 7 examples; Light degree Ⅱ Patients with Pressure Ulcers 20 examples, 8 examples are cured in medication after 15 days, and 12 examples take a turn for the better.

In therapeutic process, can by theory of Chinese medical science, within the scope of the application's claim, add and subtract each herbal medicine consumption, can reach therapeutic purposes of the present invention equally.

The diagnostic criteria that this is sick: the diagnostic criteria with reference to new edition < < Surgical Nursing > > about pressure ulcer.

The treatment standard of this disease:

Cure: skin complete, color restoration is normal;

Effective: skin color is clearly better, form a scab and even come off in ulceration place;

Effective: skin color takes a turn for the better to some extent, the existing new granulation in ulceration place forms.

Invalid: skin conditions worsens before changing not quite even.

good effect of the present invention is:

Adopt natural raw material of Chinese medicine, follow the prescriptions principle of the traditional Chinese medical science, its preparation is easy, medicine source is wide, cost is low, evident in efficacy, reliable effect, the property of medicine is gentle, has no side effect, and through clinical practice, verifies, for the damp and hot malicious stasis of blood, tie mutually, the deficiency of vital energy is the decubital ulcer of granulation promoting not for a long time, and effective percentage can reach more than 90%.

The specific embodiment

embodiment 1:

Take Radix Angelicae Sinensis 48g, Flos Lonicerae 36g, Radix Rehmanniae 36g, Radix Glycyrrhizae 36g, Radix Arnebiae (Radix Lithospermi) 48g, Herba Albiziae 12g, Olibanum 12g, Myrrha 12g, Radix Astragali 60g, Cortex Cinnamomi 60g, Flos Carthami 30g, Herba Asari 15g Margarita powder 10g, Halloysitum Rubrum 10g, Os Draconis 10g, ground beetle 5g, Radix Scrophulariae 10g, Radix Paeoniae Rubra 10g, Radix Dipsaci 10g, Rhizoma Chuanxiong 15g, Pericarpium Citri Reticulatae 10g, clean roguing, dry, pulverize, grind into powder 100 order ~ 150 orders, mix homogeneously obtains the present invention.

embodiment 2:

Radix Angelicae Sinensis 50g, Flos Lonicerae 40g, Radix Rehmanniae 30g, Radix Glycyrrhizae 30g, Radix Arnebiae (Radix Lithospermi) 50g, Herba Albiziae 8g, Olibanum 10g, Myrrha 10g, Radix Astragali 55g, Cortex Cinnamomi 55g, Flos Carthami 30g, Herba Asari 10g, Margarita powder 8g, Halloysitum Rubrum 8g, Os Draconis 5g, ground beetle 2g, Radix Scrophulariae 5g, Radix Paeoniae Rubra 8g, Radix Dipsaci 8g, Rhizoma Chuanxiong 10g, Pericarpium Citri Reticulatae 5g, clean roguing, dry, pulverize, grind into powder 100 order ~ 150 orders, mix homogeneously obtains the present invention.

embodiment 3:

Radix Angelicae Sinensis 48g, Flos Lonicerae 35g, Radix Rehmanniae 40g, Radix Glycyrrhizae 40g, Radix Arnebiae (Radix Lithospermi) 43g, Herba Albiziae 15g, Olibanum 15g, Myrrha 15g, Radix Astragali 65g, Cortex Cinnamomi 65g, Flos Carthami 35g, Herba Asari 20g, Margarita powder 13g, Halloysitum Rubrum 15g, Os Draconis 15g, ground beetle 6g, Radix Scrophulariae 15g, Radix Paeoniae Rubra 12g, Radix Dipsaci 12g, Rhizoma Chuanxiong 20g, Pericarpium Citri Reticulatae 15g, clean respectively roguing, dry, pulverize, grind into powder 100 order ~ 150 orders, mix homogeneously and get final product.

following selection portion is divided the curative effect of healing case history with explanation medicine of the present invention.

case 1

Lee, man, 72 years old, because cerebral infarction sequela causes left limb activity ineffective, lie in bed 1 year, there is the pressure ulcer of 3X3cm light degree Ⅱ in left side hip, wound surface is red and swollen, epidermis ulceration.With the embodiment of the present invention 1 medicine, smear after two weeks, red swelling of the skin disappears, and forms a scab and come off in ulceration place.

case 2

Liu, man, 60 years old, to become thin, nutritional status is poor, because of sleep at night due to chronic obstructive disease of lung, can not put down sleepingly, is interrupted semireclining position, and, there is the pressure ulcer of I degree in sacrococcygeal region skin rubefaction.Use the embodiment of the present invention 2 medicines one day after, it is normal that skin color recovers.Pressure ulcer recovery from illness.

case 3

Wang, female, 80 years old, to lie in bed 5 years, the pressure ulcer of sacrococcygeal region light degree Ⅱ, has blister ulceration, area 5X5cm; With gradually light after the embodiment of the present invention 3 Drug therapy first quarter moons, continuous use is healed after one month entirely.

Claims (3)

1. treat a Chinese medicine preparation for pressure ulcer, mainly by following raw materials by weight portion than making:

Radix Angelicae Sinensis 45 ~ 50, Flos Lonicerae 35 ~ 40, Radix Rehmanniae 30 ~ 40, Radix Glycyrrhizae 30 ~ 40, Radix Arnebiae (Radix Lithospermi) 43 ~ 50, Herba Albiziae 8 ~ 15, Olibanum 10 ~ 15, Myrrha 10 ~ 15, the Radix Astragali 55 ~ 65, Cortex Cinnamomi 55 ~ 65, Flos Carthami 25 ~ 35, Herba Asari 10 ~ 20, Margarita powder 8 ~ 13, Halloysitum Rubrum 8 ~ 15, Os Draconis 5 ~ 15, ground beetle 2 ~ 6, Radix Scrophulariae 5 ~ 15, Radix Paeoniae Rubra 8 ~ 12, Radix Dipsaci 8 ~ 12, Rhizoma Chuanxiong 10 ~ 20, Pericarpium Citri Reticulatae 5 ~ 15.

2. the Chinese medicine preparation for the treatment of pressure ulcer claimed in claim 1, optimum ratio is:

Radix Angelicae Sinensis 48, Flos Lonicerae 36, Radix Rehmanniae 36, Radix Glycyrrhizae 36, Radix Arnebiae (Radix Lithospermi) 48, Herba Albiziae 12, Olibanum 12, Myrrha 12, the Radix Astragali 60, Cortex Cinnamomi 60, Flos Carthami 30, Herba Asari 15, Margarita powder 10, Halloysitum Rubrum 10, Os Draconis 10, ground beetle 5, Radix Scrophulariae 10, Radix Paeoniae Rubra 10, Radix Dipsaci 10, Rhizoma Chuanxiong 15, Pericarpium Citri Reticulatae 10.

3. the preparation technology of the Chinese medicine preparation of the treatment pressure ulcer described in claim 1 or 2, comprises the following steps:

Clean respectively roguing, dry, pulverize, grind into powder 100 order ~ 150 orders, mix homogeneously and get final product.