CN101361820A - Traditional Chinese medicine combination for clearing away the heat-evil and expelling superficial evils, bacterial resisting and diminishing inflammation, preventing asthma and relieving cough and pr - Google Patents

Traditional Chinese medicine combination for clearing away the heat-evil and expelling superficial evils, bacterial resisting and diminishing inflammation, preventing asthma and relieving cough and pr Download PDF

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Publication number
CN101361820A
CN101361820A CNA2008101513536A CN200810151353A CN101361820A CN 101361820 A CN101361820 A CN 101361820A CN A2008101513536 A CNA2008101513536 A CN A2008101513536A CN 200810151353 A CN200810151353 A CN 200810151353A CN 101361820 A CN101361820 A CN 101361820A
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China
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chinese medicine
radix scutellariae
radix
inflammation
heat
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CNA2008101513536A
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Chinese (zh)
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董爱国
高木珍
王磊
任鸿春
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TIANJIN BIJIA PHARMACEUTICAL GROUP CO Ltd
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TIANJIN BIJIA PHARMACEUTICAL GROUP CO Ltd
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Priority to CNA2008101513536A priority Critical patent/CN101361820A/en
Publication of CN101361820A publication Critical patent/CN101361820A/en
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Abstract

The invention relates to a traditional Chinese medicine composite that can clear away heat and toxic material, eliminate inflammation and relieve cough and asthma and a preparation method thereof, which is composed of Chinese ephedra, radix scutellariae, isatis root, forsythia, coptis root, and the like has effects in clearing away heat and toxic material, eliminating inflammation and relieving cough and asthma and the like and is clinically applied to such diseases as infectious bronchitis, laryngotracheitis, infective rhinitis, flu and the like. The effective constituents of the Chinese ephedra, the monarch drug in the composite of the invention, are ephedrine and pseudoephedrine, and the Chinese ephedra can drive sweating, prevent asthma, prevent cough and eliminate sputum, and has effects in relieving fever, resisting bacteria, resisting virus and the like. The radix scutellariae is bitter and cold in nature and pertains to lung, gut and spleen channel, and has effect in clearing away heat and toxic material, eliminating inflammation and the like. The traditional Chinese medicine composition of the invention purely belongs to a Chinese materia medica preparation and has advantages of easy storage, availability to long-distance transportation, and easy controlling, fast dissolving, absorption facilitating and quick effecting of dose in use, definite curative effect and no medicine residue left, thus being capable of meeting the requirements of green veterinary medicine.

Description

A kind of heat-clearing and toxic substances removing, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of heat-clearing and toxic substances removing, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition and preparation method thereof.
Background technology
In the agricultural industry adjustment process, animal husbandry proportion increases gradually, and eqpidemic disease becomes the key factor of restriction animal husbandry development.China's veterinary drug production development is very slow, and the product of original creation does not almost have.Particularly in the broiler outlet, developed country especially European Union claims green barrier again with eqpidemic disease and the residual technology barriers of having erected of medicine, although European Union to opening-up of china meat market, does not also have the meat of China to go on the market in European Union so far at animal products.In order to solve problems such as the disabling of some chemical drugss, teratogenesis, people have turned to Chinese herbal medicine with sight.Domestic present veterinary drug kind is more, but Chinese herbal medicine for animals (comprising preparation) quality standard is qualitative rather than quantitative to effective ingredient always, and technology is coarse, the quality instability, and uncertain therapeutic efficacy is cut, and is unfavorable for the development of herbal medicine.
Summary of the invention
One of purpose of the present invention is to overcome the deficiencies in the prior art, and heat-clearing and toxic substances removing, the anti-inflammation of a kind of good effect, no drug residue, the Chinese medicine composition of antiasthmatic-antitussive are provided.
Another object of the present invention provides the preparation method of above-mentioned Chinese medicine composition.
The present invention solves its technical problem and is achieved through the following technical solutions:
A kind of heat-clearing and toxic substances removing, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition, it constitutes component and parts by weight are respectively:
Herba Ephedrae 18-20 part Radix Glycyrrhizae 9-11 part Herba Andrographis 9-11 part Radix Sophorae Tonkinensis 9-11 part
Herba Taraxaci 9-11 part Radix Isatidis 9-11 part Gypsum Fibrosum 9-11 part
Fructus Forsythiae 6-8 part Radix Scutellariae 4-6 part Rhizoma Coptidis 2-4 part.
The preparation method of a kind of heat-clearing and toxic substances removing, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition, the step of its preparation method is:
(1). took by weighing by weight Radix Scutellariae and alcohol extraction 1-3 hour, and filtered, the Radix Scutellariae medicinal residues that leach are standby, reclaim the ethanol of extracting solution, and it is standby to collect Radix Scutellariae extract;
(2). take by weighing Herba Ephedrae, Radix Glycyrrhizae, Herba Andrographis, Radix Sophorae Tonkinensis, Herba Taraxaci, Radix Isatidis, Gypsum Fibrosum, Fructus Forsythiae, Rhizoma Coptidis by weight, and fully mix with the Radix Scutellariae medicinal residues, decocting 1-2 time, the time is 1-3 hour, vacuum decompression concentrates then, obtains concentrated solution;
(3). concentrated solution is adopted the ethanol precipitate with ethanol, reclaim ethanol then, obtain mixed extract;
(4). in mixed extract, add Radix Scutellariae extract, promptly obtain the effective ingredient of Chinese medicine composition behind the mix homogeneously, can granulate then, granulate becomes finished product.
3. the preparation method of a kind of heat-clearing and toxic substances removing according to claim 2, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition is characterized in that: described Radix Scutellariae alcohol extraction is that the ethanol of employing 45% carries out alcohol extraction under 80 ℃ of temperature conditions.
Advantage of the present invention and beneficial effect are:
1. this Chinese medicine composition has strict quality standard and quality assurance system, to improve the inherent quality of quality standard control product, improve extracting technique of Chinese medicine, improve the conversion ratio of medical material, guarantee the curative effect of herbal medicine product, be a kind of green veterinary drug of no drug residue, have the good efficacy of heat-clearing and toxic substances removing, anti-inflammation, antiasthmatic-antitussive.
2. this Chinese medicine composition is controlled by intermediate, determines controlled condition such as temperature, time etc. in the extraction process, and fully effective component extracting improves the Chinese crude drug utilization rate, makes constant product quality, and curative effect is reliable.
3. this Chinese medicine composition using method is based on drinking-water, requires moltenly entirely in water, so preparation process avoided adjuvants such as water-fast starch, dextrin, all adopts water-soluble adjuvant, shows feasible process through study on the stability, constant product quality.
4. this Chinese medicine composition belongs to pure Chinese medicinal preparation, is easy to preserve, and can transport for long-distance, and dosage is grasped easily, dissolved rapidly, is convenient to absorption, rapid-action during use, determined curative effect, and no drug residue can reach the requirement of green veterinary drug.
5. this Chinese medicine composition is main object of study with monarch drug, the innovation extraction process, fully extract main effective ingredient, according to veterinary drug GMP standard, based on Chinese veterinarian's experience, adopt the herbal medicine of the good effect of modern detection means and modern pharmaceutical equipment development, nuisanceless, noresidue, taking convenience.
6. this Chinese medicine composition is made granule with the main component of monarch drug, improves granular mass or yield rate, improves quality standard, improves technology, strengthens quality control process, the screening authentic medicinal herbs, and constant product quality, with low cost, good effect, the product market competition ability is strong.
The specific embodiment
The invention will be further described below by specific embodiment, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
A kind of heat-clearing and toxic substances removing, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition, it constitutes component and parts by weight are respectively:
Herba Ephedrae 18g Radix Glycyrrhizae 10g Herba Andrographis 10g Radix Sophorae Tonkinensis 10g Herba Taraxaci 10g
Radix Isatidis 10g Gypsum Fibrosum 10g Fructus Forsythiae 7g Radix Scutellariae 5g Rhizoma Coptidis 3g.
The preparation method of a kind of heat-clearing and toxic substances removing, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition, the step of preparation method is:
(1). take by weighing Radix Scutellariae and adopt the alcohol extraction 2 hours under about 80 ℃ of temperature conditions of 45% ethanol, filter, the Radix Scutellariae medicinal residues that leach are standby, reclaim the ethanol of extracting solution, and it is standby to collect Radix Scutellariae extract;
(2). take by weighing Herba Ephedrae, Radix Glycyrrhizae, Herba Andrographis, Radix Sophorae Tonkinensis, Herba Taraxaci, Radix Isatidis, Gypsum Fibrosum, Fructus Forsythiae, Rhizoma Coptidis by weight and fully mix with the Radix Scutellariae medicinal residues, decocting twice, the time is 2 hours, vacuum decompression concentrates then, obtains concentrated solution;
(3). concentrated solution is adopted 70% ethanol precipitate with ethanol, reclaim ethanol then, obtain mixed extract;
(4). in mixed extract, add Radix Scutellariae extract, promptly obtain the effective ingredient of Chinese medicine composition behind the mix homogeneously, can granulate then, granulate becomes finished product.
Pharmacology of the present invention is:
The effective ingredient of monarch drug Herba Ephedrae is ephedrine, pseudoephedrine, and the Herba Ephedrae diaphoresis is relievingd asthma, relieving cough and expelling phlegm and have effects such as analgesic, antibiotic, antiviral; Radix Scutellariae nature and flavor hardship, cold, return lung, gallbladder, spleen channel, have effects such as heat-clearing and toxic substances removing, anti-inflammation.The effective ingredient that plays a major role in the present invention's prescription is mainly compositions such as ephedrine, baicalin, berberine, can clinically be used for infectious bronchitis of chicken, laryngotracheitis, diseases such as infective rhinitis and influenza.

Claims (3)

1. a heat-clearing and toxic substances removing, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition, it is characterized in that: it constitutes component and parts by weight are respectively:
Herba Ephedrae 18-20 part Radix Glycyrrhizae 9-11 part Herba Andrographis 9-11 part Radix Sophorae Tonkinensis 9-11 part
Herba Taraxaci 9-11 part Radix Isatidis 9-11 part Gypsum Fibrosum 9-11 part
Fructus Forsythiae 6-8 part Radix Scutellariae 4-6 part Rhizoma Coptidis 2-4 part.
2. the preparation method of an a kind of heat-clearing and toxic substances removing as claimed in claim 1, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition, it is characterized in that: the step of preparation method is:
(1). took by weighing by weight Radix Scutellariae and alcohol extraction 1-3 hour, and filtered, the Radix Scutellariae medicinal residues that leach are standby, reclaim the ethanol of extracting solution, and it is standby to collect Radix Scutellariae extract;
(2). take by weighing Herba Ephedrae, Radix Glycyrrhizae, Herba Andrographis, Radix Sophorae Tonkinensis, Herba Taraxaci, Radix Isatidis, Gypsum Fibrosum, Fructus Forsythiae, Rhizoma Coptidis by weight, and fully mix with the Radix Scutellariae medicinal residues, decocting 1-2 time, the time is 1-3 hour, vacuum decompression concentrates then, obtains concentrated solution;
(3). concentrated solution is adopted the ethanol precipitate with ethanol, reclaim ethanol then, obtain mixed extract;
(4). in mixed extract, add Radix Scutellariae extract, promptly obtain the effective ingredient of Chinese medicine composition behind the mix homogeneously, can granulate then, granulate becomes finished product.
3. the preparation method of a kind of heat-clearing and toxic substances removing according to claim 2, anti-inflammation, antiasthmatic-antitussive Chinese medicine composition is characterized in that: described Radix Scutellariae alcohol extraction is that the ethanol of employing 45% carries out alcohol extraction under 80 ℃ of temperature conditions.
CNA2008101513536A 2008-09-17 2008-09-17 Traditional Chinese medicine combination for clearing away the heat-evil and expelling superficial evils, bacterial resisting and diminishing inflammation, preventing asthma and relieving cough and pr Pending CN101361820A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102178752A (en) * 2010-12-08 2011-09-14 叶建斌 Prescription of effervescent tablet for clearing away heat and toxic material and preparation method thereof
CN104306441A (en) * 2014-10-13 2015-01-28 天津瑞贝特科技发展有限公司 Traditional Chinese medicine oral solution for treating swine influenza and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102178752A (en) * 2010-12-08 2011-09-14 叶建斌 Prescription of effervescent tablet for clearing away heat and toxic material and preparation method thereof
CN104306441A (en) * 2014-10-13 2015-01-28 天津瑞贝特科技发展有限公司 Traditional Chinese medicine oral solution for treating swine influenza and preparation method thereof

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Open date: 20090211