CN101357186A - Preparation method of medicine for treating the prostatitis - Google Patents
Preparation method of medicine for treating the prostatitis Download PDFInfo
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- CN101357186A CN101357186A CNA2008103046232A CN200810304623A CN101357186A CN 101357186 A CN101357186 A CN 101357186A CN A2008103046232 A CNA2008103046232 A CN A2008103046232A CN 200810304623 A CN200810304623 A CN 200810304623A CN 101357186 A CN101357186 A CN 101357186A
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Abstract
The invention relates to a preparation method of a medicine used for treating prostate diseases, namely, prostate health granules for treating chronic prostatitis and prostatic hyperplasia. The medicine is made from 15 medicinal materials such as bark of Chinese corktree, honeysuckle flower, etc. More particularly, the medicine is made by the following steps: the bark of Chinese corktree and corydalis tuber are crashed into crude grains, red sage root is crashed properly, and then the three medicinal materials and epimeddium herb are heated by ethanol and extracted by refluxing for twice with each time lasting for 2 hours and the added ethanol of each time being 7 times, thus two extracting solutions are obtained; the obtained extracting solutions are filtered while hot so as to obtain two filtrates, which are mixed to obtain a mixture, the ethanol is recovered, and the mixture is properly condensed into a liquor for use; the dregs and 11 medicinal materials including the honeysuckle flower are decocted in water for twice with each time lasting for 2 hours and the added water of each time being 8 times, thus two decoctions are obtained, and the two obtained decoctions are filtered while hot and the filtrates obtained are mixed to obtain a mixture, which is mixed with the liquor, and decompressed and condensed into a clear paste with the density of 1.1-1.4; the clear paste is added and evenly mixed with a proper amount of dextrin, decompressed and dried, crashed into fine powder, added and evenly mixed with proper amounts of fine sodium cyclamate powder and fine sodium carboxymethyl cellulose powder respectively, and made into granules by ethanol; the granules are dried and filled to obtained the prostate health granules. The medicine obtained has good and reliable curative effect.
Description
Technical field
The present invention relates to a kind of preparation method of Chinese medicine preparation, promptly treat the preparation method of prostatosis medicine.
Background technology
In prior art, diseases such as chronic prostatitis, prostatic hyperplasia are andrology's commonly encountered diseases, it is reported, the acute and chronic prostatitis sickness rate of male is up to more than 30% more than 35 years old.Reports such as Harbitz find that in the obduction of 206 examples more than 40 years old 165 people have prostatic hyperplasia, and sickness rate is up to 80.1%, and the sickness rate of China is also very high.Therefore, development curative to the ill is very meaningful.Peace granule in prostatitis is used for the treatment of chronic prostatitis, prostatic hyperplasia, and it is by Cortex Phellodendri 4-5 part, Flos Lonicerae 10-14 part, Rhizoma Smilacis Glabrae 10-14 part, Rhizoma Polygoni Cuspidati 10-14 part, Herba Hedyotidis Diffusae 6-8 part, Semen Plantaginis (stir-fry) 5-7 part, 1 part of Rhizoma Corydalis (vinegar system), Radix Salviae Miltiorrhizae 4-6 part, Pheretima 4-5 part, Semen Vaccariae (stir-fry) 4-5 part, Radix Astragali 3-5 part, Herba Epimedii (system) 3-5 part, Radix Rehmanniae Preparata 2-4 part, 1 part of Fructus Corni, Spina Gleditsiae 4-5 part crude drug is prepared from.Has clearing away heat-damp and promoting diuresis, the blood stasis dispelling function for tonifying kidney.After being used for prostatic hyperplasia, chronic prostatitis and the frequent micturition that causes by prostatitis, urgent micturition, dysurea, urine the sound of rain pattering not to the utmost, diseases such as sexual hypofunction.
Summary of the invention
The objective of the invention is provides a kind of preparation method that guarantees the treatment prostatosis medicine of curative effect at foregoing.
Technical solution of the present invention is: the preparation method step of treatment prostatosis medicine is as follows:
A, raw material: Cortex Phellodendri 4-5 part, Flos Lonicerae 10-14 part, Rhizoma Smilacis Glabrae 10-14 part, Rhizoma Polygoni Cuspidati 10-14 part, Herba Hedyotidis Diffusae 6-8 part, parch Semen Plantaginis 5-7 part, 1 part of Rhizoma Corydalis (processed with vinegar), Radix Salviae Miltiorrhizae 4-6 part, Pheretima 4-5 part, parch Semen Vaccariae 4-5 part, Radix Astragali 3-5 part, Herba Epimedii (processed) 3-5 part, Radix Rehmanniae Preparata 2-4 part, 1 part of Fructus Corni, Spina Gleditsiae 4-5 part.
B, more than ten five tastes, Cortex Phellodendri, Rhizoma Corydalis is ground into coarse granule, and Radix Salviae Miltiorrhizae is given as one thinks fit cataclasm, this three flavor extracts 1-4 time with the 40-90% alcohol heating reflux in the lump with Herba Epimedii, and each 1-3 hour, each alcohol adding amount was 4-11 times, filter while hot, merging filtrate reclaims ethanol, suitably concentrates, medicinal liquid is standby, medicinal residues and Flos Lonicerae etc. ten decocts with water 1-4 time simply, and each 1-3 hour, each amount of water was 5-10 times, filter while hot, merging filtrate, and merge with above-mentioned medicinal liquid, be evaporated to the clear paste of 1.1-1.4 (50 ℃ of surveys), add an amount of dextrin mixing, drying under reduced pressure is ground into fine powder, makes medicament.
Preferred version is that step is as follows:
A, raw material: Cortex Phellodendri 4-5 part, Flos Lonicerae 10-14 part, Rhizoma Smilacis Glabrae 10-14 part, Rhizoma Polygoni Cuspidati 10-14 part, Herba Hedyotidis Diffusae 6-8 part, parch Semen Plantaginis 5-7 part, 1 part of Rhizoma Corydalis (processed with vinegar), Radix Salviae Miltiorrhizae 4-6 part, Pheretima 4-5 part, parch Semen Vaccariae 4-5 part, Radix Astragali 3-5 part, Herba Epimedii (processed) 3-5 part, Radix Rehmanniae Preparata 2-4 part, 1 part of Fructus Corni, Spina Gleditsiae 4-5 part;
B, above ten five tastes, Cortex Phellodendri, Rhizoma Corydalis are ground into coarse granule, and Radix Salviae Miltiorrhizae is given as one thinks fit cataclasm, this three flavor extracts 2 times with 75% alcohol heating reflux in the lump with Herba Epimedii, and each 2 hours, each alcohol adding amount was 7 times, filter while hot, merging filtrate reclaims ethanol, suitably concentrates, medicinal liquid is standby, medicinal residues and Flos Lonicerae etc. ten decocts with water 2 times simply, and each 2 hours, each amount of water was 8 times, filter while hot, merging filtrate, and merge with above-mentioned medicinal liquid, be evaporated to the clear paste of 1.1-1.4 (50 ℃ of surveys), add an amount of dextrin mixing, drying under reduced pressure is ground into fine powder, makes medicament.
Can be mixed and made into tablet, capsule (soft capsule), granule, powder, pill, liquid preparation or other conventional formulation by pharmaceutical carrier, additive or adjuvant commonly used in above-mentioned each medicinal raw material and the pharmacy, be preferably granule.
Advantage of the present invention is: according to the difference of composition chemical property in the raw medicinal material, water or ethanol carry out whole part and extract respectively, and keep and improved active constituent content, good stability, the pharmacodynamic experiment effect is remarkable.Clinical trial confirms, the pharmaceutical effectiveness ideal that obtains, reliable.
Below in conjunction with embodiment embodiments of the present invention are described in further detail.
The specific embodiment
Embodiment: prostatitis peace preparation method of granules
Prostatitis peace preparation method of granules step is as follows:
A, raw material: 4.5 parts of Cortex Phellodendris, 11 parts of Flos Loniceraes, 11 parts of Rhizoma Smilacis Glabraes, 11 parts of Rhizoma Polygoni Cuspidati, 7.5 parts of Herba Hedyotidis Diffusaes, 5.5 parts of parch Semen Plantaginiss, 1 part of Rhizoma Corydalis (processed with vinegar), 5.5 parts of Radix Salviae Miltiorrhizaes, 4.5 parts of Pheretimas, 4.5 parts of parch Semen Vaccariae, 3.5 parts of the Radixs Astragali, 3.5 parts of Herba Epimedii (processed), 2.5 parts of Radix Rehmanniae Preparata, 1 part of Fructus Corni, 4.5 parts of Spina Gleditsiaes;
B, more than ten five tastes, Cortex Phellodendri, Rhizoma Corydalis is ground into coarse granule, and Radix Salviae Miltiorrhizae is given as one thinks fit cataclasm, this three flavor extracts 2 times with 75% alcohol heating reflux in the lump with Herba Epimedii, and each 2 hours, each alcohol adding amount was 7 times, filter while hot, merging filtrate reclaims ethanol, suitably concentrate, medicinal liquid is standby, and medicinal residues and Flos Lonicerae etc. ten decoct with water each 2 hours simply 2 times, each amount of water is 8 times, filter while hot, merging filtrate, and merge with above-mentioned medicinal liquid, be evaporated to the clear paste of 1.1-1.4 (50 ℃ of surveys), add an amount of dextrin mixing, drying under reduced pressure is ground into fine powder, add an amount of cyclamate fine powder and sodium carboxymethyl cellulose fine powder, mixing is made granule with ethanol, drying, packing, promptly.
Claims (3)
1. preparation method for the treatment of the prostatosis medicine is characterized in that step is as follows:
A, raw material: Cortex Phellodendri 4-5 part, Flos Lonicerae 10-14 part, Rhizoma Smilacis Glabrae 10-14 part, Rhizoma Polygoni Cuspidati 10-14 part, Herba Hedyotidis Diffusae 6-8 part, parch Semen Plantaginis 5-7 part, 1 part of Rhizoma Corydalis (processed with vinegar), Radix Salviae Miltiorrhizae 4-6 part, Pheretima 4-5 part, parch Semen Vaccariae 4-5 part, Radix Astragali 3-5 part, Herba Epimedii (processed) 3-5 part, Radix Rehmanniae Preparata 2-4 part, 1 part of Fructus Corni, Spina Gleditsiae 4-5 part;
B, more than ten five tastes, Cortex Phellodendri, Rhizoma Corydalis is ground into coarse granule, and Radix Salviae Miltiorrhizae is given as one thinks fit cataclasm, this three flavor extracts 1-4 time with the 40-90% alcohol heating reflux in the lump with Herba Epimedii, and each 1-3 hour, each alcohol adding amount was 4-11 times, filter while hot, merging filtrate reclaims ethanol, suitably concentrates, medicinal liquid is standby, medicinal residues and Flos Lonicerae etc. ten decocts with water 1-4 time simply, and each 1-3 hour, each amount of water was 5-10 times, filter while hot, merging filtrate, and merge with above-mentioned medicinal liquid, be evaporated to the clear paste that density is 1.1-1.4, add auxiliary materials and mixing, drying under reduced pressure is ground into fine powder, makes medicament.
2. according to the preparation method of the described treatment prostatosis of claim 1 medicine, it is characterized in that step is as follows:
A, raw material: Cortex Phellodendri 4-5 part, Flos Lonicerae 10-14 part, Rhizoma Smilacis Glabrae 10-14 part, Rhizoma Polygoni Cuspidati 10-14 part, Herba Hedyotidis Diffusae 6-8 part, parch Semen Plantaginis 5-7 part, 1 part of Rhizoma Corydalis (processed with vinegar), Radix Salviae Miltiorrhizae 4-6 part, Pheretima 4-5 part, parch Semen Vaccariae 4-5 part, Radix Astragali 3-5 part, Herba Epimedii (processed) 3-5 part, Radix Rehmanniae Preparata 2-4 part, 1 part of Fructus Corni, Spina Gleditsiae 4-5 part;
B, above ten five tastes, Cortex Phellodendri, Rhizoma Corydalis are ground into coarse granule, and Radix Salviae Miltiorrhizae is given as one thinks fit cataclasm, this three flavor extracts 2 times with 75% alcohol heating reflux in the lump with Herba Epimedii, and each 2 hours, each alcohol adding amount was 7 times, filter while hot, merging filtrate reclaims ethanol, suitably concentrates, medicinal liquid is standby, medicinal residues and Flos Lonicerae etc. ten decocts with water 2 times simply, and each 2 hours, each amount of water was 8 times, filter while hot, merging filtrate, and merge with above-mentioned medicinal liquid, be evaporated to the clear paste that density is 1.1-1.4, add auxiliary materials and mixing, drying under reduced pressure is ground into fine powder, makes medicament.
3. according to the preparation method of the described treatment prostatosis of claim 1 medicine, it is characterized in that step is as follows:
A, raw material: 4.5 parts of Cortex Phellodendris, 11 parts of Flos Loniceraes, 11 parts of Rhizoma Smilacis Glabraes, 11 parts of Rhizoma Polygoni Cuspidati, 7.5 parts of Herba Hedyotidis Diffusaes, 5.5 parts of parch Semen Plantaginiss, 1 part of Rhizoma Corydalis (processed with vinegar), 5.5 parts of Radix Salviae Miltiorrhizaes, 4.5 parts of Pheretimas, 4.5 parts of parch Semen Vaccariae, 3.5 parts of the Radixs Astragali, 3.5 parts of Herba Epimedii (processed), 2.5 parts of Radix Rehmanniae Preparata, 1 part of Fructus Corni, 4.5 parts of Spina Gleditsiaes;
B, more than ten five tastes, Cortex Phellodendri, Rhizoma Corydalis is ground into coarse granule, and Radix Salviae Miltiorrhizae is given as one thinks fit cataclasm, this three flavor extracts 2 times with 75% alcohol heating reflux in the lump with Herba Epimedii, and each 2 hours, each alcohol adding amount was 7 times, filter while hot, merging filtrate reclaims ethanol, suitably concentrate, medicinal liquid is standby, and medicinal residues and Flos Lonicerae etc. ten decoct with water 2 times simply, each 2 hours, each amount of water was 8 times, filters while hot, merging filtrate, and merge with above-mentioned medicinal liquid, be evaporated to the clear paste that density is 1.1-1.4, add the dextrin mixing, drying under reduced pressure is ground into fine powder, add cyclamate fine powder and sodium carboxymethyl cellulose fine powder, mixing is made granule with ethanol, drying, packing, promptly.
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CNA2008103046232A CN101357186A (en) | 2008-09-24 | 2008-09-24 | Preparation method of medicine for treating the prostatitis |
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CNA2008103046232A CN101357186A (en) | 2008-09-24 | 2008-09-24 | Preparation method of medicine for treating the prostatitis |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106798849A (en) * | 2017-02-14 | 2017-06-06 | 四川双鑫生物科技有限公司 | It is a kind of to treat suppository drug of chronic prostatitis and preparation method thereof |
CN108607060A (en) * | 2016-12-12 | 2018-10-02 | 董早霞 | Qi and activate blood circulation preparation |
-
2008
- 2008-09-24 CN CNA2008103046232A patent/CN101357186A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108607060A (en) * | 2016-12-12 | 2018-10-02 | 董早霞 | Qi and activate blood circulation preparation |
CN106798849A (en) * | 2017-02-14 | 2017-06-06 | 四川双鑫生物科技有限公司 | It is a kind of to treat suppository drug of chronic prostatitis and preparation method thereof |
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Open date: 20090204 |