CN101342329A - Medicament composition for treating dyspepsia - Google Patents

Abstract

The present invention discloses a medicinal composition which is used for treating dyspepsia, and comprises the following ingredients: 45 to 50 portions of large hawthorn, 45 to 55 portions of malt, 45 to 55 portions of medicated leaven, 50 to 80 portions of mung beans, 45 to 55 portions of Astraolylis lancea formalyrata, 40 to 55 portions of folium perillae acutae, 70 to 80 portions of baked licorice, 45 to 55 portions of bark of official magnolia, 60 to 80 portions of dandelion, and 45 to 65 portions of corydalis tuber. The medicinal composition can be used for treating the dyspepsia, and has the advantages of simple preparation process, significant effects, and low costs.

Description

The dyspeptic pharmaceutical composition of a kind of treatment

Technical field

The present invention relates to a kind of pharmaceutical composition and preparation method thereof, medicine of treatment functional dyspepsia and preparation method thereof.

Background technology

Dyspepsia is a kind of caused by gastric motility disorder Disease, also comprise gastroparesis and esophageal regurgitation disease that gastric peristalsis is bad.Symptom shows as epigastric discomfort or pain by spells, glutted, heartburn (acid regurgitation), belch etc.Often be reluctant also to be difficult for feed or few as far as possible feed sleeping peacefully at night, nightmare is often arranged after sleeping because of discomforts such as sense uncomfortable in chest, early full, abdominal distention.To examination in hospital, remove GastroscopeUnder can see light-duty GastritisOutward, other are checked as B ultrasonic, X-ray radiography and blood biochemistry checking etc., all can not check out abnormal performance.Cause that dyspeptic reason is a lot, comprise harmonization of the stomach DuodenumThe chronic inflammatory disease at position makes Esophagus, Stomach, duodenal normal creepage of gastrointestinal functions functional disorder. The patientSpirit unhappy, long-term depressed or be subjected to fierce stimulation etc. suddenly and all can cause.The helmet paresis then is by due to diabetes, constitutional anorexia nervosa and the gastrectomy.The year people's DigestionHypofunction is subject to EmotionInfluence is when depositing FoodAlso can bring out when coarse slightly or the raw and cold and too much mistake of food is greasy.What be worth emphasizing is, the general light-duty dyspepsia of Heal Thyself at home mostly because too nervous, day cold suffer from cold or the nondigestible food of polyphagia causes of feeling bad, work, only has slight epigastric discomfort, symptom such as glutted, heartburn.Dyspeptic classification: dyspepsia mainly is divided into functional dyspepsia and organic dyspepsia.Functional dyspepsia---above-mentioned indigestion symptom is arranged, but do not find significantly on inspection Digestive organsDisease or systemic disease, this type of dyspepsia incidence rate is the highest, and most people have experience.Main and the spiritual psychological factor of pathogenic factor is relevant, as anxious state of mind, and sleep state, it is bad to have a rest, tobacco and wine stimulation etc.Organic dyspepsia: can clearly assert and cause indigestion symptom through checking by certain organ lesion, as hepatopathy, biliary tract, pancreatic diseases, diabetes etc.For these patients, be primarily aimed at etiological treatment in the time of treatment, assist supplementing digestive enzyme or improve gastric motility and alleviate indigestion symptom.So indigestion symptom after taking place should in time be checked at first to confirm whether follow other disease.But the dyspeptic medicine of treatment in the market is a lot, but real thorough treatment, and obvious results is but seldom.

Summary of the invention

Purpose of the present invention just provides a kind of special for treating functional dyspepsia and the pharmaceutical composition that has no side effect and preparation method thereof.

The present invention is made up of following compositions and weight ratio:

Big Fructus Crataegi 45-50 Fructus Hordei Germinatus 45-55 Massa Medicata Fermentata 45-55 Semen phaseoli radiati 50-80 Rhizoma Atractylodis Macrocephalae 45-55 Folium Perillae 40-55 Radix Glycyrrhizae Preparata 70-80 Cortex Magnoliae Officinalis 45-55 Herba Taraxaci 60-80 Rhizoma Corydalis 45-65

Its preparation method is: (1) gets big Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata, Semen phaseoli radiati, the Rhizoma Atractylodis Macrocephalae, Folium Perillae, Radix Glycyrrhizae Preparata, Cortex Magnoliae Officinalis, Herba Taraxaci, Rhizoma Corydalis nine flavors place the Chinese medicine multi-functional extractor, add 2 times of water gagings, heating decocts twice, kept little 90-140 of boiling minute for the first time, kept little 40-70 of boiling minute for the second time, merge decoction liquor twice, filter, being concentrated into density is the thick extractum of 1.2-1.5, simultaneously, collects the volatile oil that distributes when decocting; (2) add excipient in thick extractum, make granule, dry under 65-80 ℃, moisture is 3-6%; (3) on dried granule, spray volatile oil, seal 100-130 minute, behind the granulate, add lubricant, mix homogeneously, tabletting.

Big Fructus Crataegi can be whetted the appetite in the prescription of the present invention, and appetite stimulator is aid digestion; The Fructus Hordei Germinatus nature and flavor are sweet flat, the energy promoting digestion and invigorating the stomach, and Compendium of Material Medica is thought can digest all fruit food stagnations of all rice and flour; The Massa Medicata Fermentata stomach function regulating therapeutic method to keep the adverse QI flowing downwards that can help digestion, the contrary all gas of distension of expectorant; The Semen phaseoli radiati promoting digestion and removing stagnation, outstanding benefaction gas relieving distension; Three medicines share the merit that can strengthen relieving dyspepsia, are used for the treatment of the primary symptom of upper abdominal pain, big belly, are monarch drug altogether.Rhizoma Atractylodis Macrocephalae bitter but sweet flavor temperature, energy air making-up and spleen enlivening, dampness, " book on Chinese herbal medicine converges and says " thinks that the Rhizoma Atractylodis Macrocephalae is for fostering taste, wet dissipation, helping digestion except that the key medicine of painful abdominal mass; Folium Perillae can promoting the circulation of QI to alleviate the stagnation in middle-JIAO, separates the poison of fish Eriocheir sinensis again, is the good medicine of the activating QI to stop vomiting of being amusing; The invigorating middle warmer of Radix Glycyrrhizae Preparata energy QI invigorating, detoxifcation, emergency, and transfer the property of medicine; Three medicines share can be strengthened strengthening the spleen and stomach, the effect that removing dampness is amusing, be used for the treatment of vomiting, eh, symptom such as full early, be ministerial drug altogether.The arduous temperature of Cortex Magnoliae Officinalis nature and flavor can circulation of qi promoting, dampness, removing food stagnancy, is the key medicine of removing distension, Herba Taraxaci heat-clearing and toxic substances removing, the dampness stagnant gas that can loose; The pain relieving of Rhizoma Corydalis blood-activating and qi-promoting is used for all pain diseases of the stagnation of QI; Three medicines share can strengthen heat clearing and damp drying, and the effect of promoting the circulation of QI to relieve pain is used for strengthening treatment stomachache, abdominal distention, increases the effect of clearing heat and expelling damp, is adjuvant altogether.More than all medicines share gather altogether that food stagnation removingization stagnates, the merit of invigorating the spleen to clear away damp pathogen, regulating QI to relieve pain,

The specific embodiment

Below in conjunction with embodiment, the invention will be further described.

Embodiment one

Getting the big Fructus Crataegi 45 gram Fructus Hordei Germinatus 45 gram Massa Medicata Fermentata 45 gram Semen phaseoli radiatis 50 gram Rhizoma Atractylodis Macrocephalaes 45 gram Folium Perillaes 40 gram Radix Glycyrrhizae Preparatas 70 gram Cortex Magnoliae Officinalis restrains 55 Herba Taraxacis, 60 gram Rhizoma Corydalis, 50 grams and places the Chinese medicine multi-functional extractor (the upright Chinese medicine equipment in Wuhan manufacturing company produces, model TwL-1000) in, add 700 gram water, heating decocts twice, the boiling back keeps little boiling 100 minutes for the first time, boil to the saturating heart of medical material, for the second time keeping little boiled 40 minutes, boil to the medical material abnormal smells from the patient thin, merge decoction liquor twice, filter, be concentrated into density and be 1.5 thick extractum, simultaneously, collect the volatile oil that distributes when decocting; In thick extractum, add excipient starch 20 gram, mix homogeneously, adding distil water, after crossing 16 mesh sieves and making soft material, wet grain 60 ℃ dry down, moisture is 2.5%; Spray volatile oil on dried granule, sealing was placed 100 minutes, and behind the granulate, power mouth lubricant Pulvis Talci 10 grams of going into to flow are put in the mixer after the mixing, are pressed into tablet with tablet machine.

Embodiment two

Get 50 kilograms in 55 kilograms of Fructus Hordei Germinatus of big Fructus Crataegi, 50 kilograms of Massa Medicata Fermentata, 75 kilograms in Semen phaseoli radiati, 50 kilograms of the Rhizoma Atractylodis Macrocephalaes, 50 kilograms of Folium Perillae, 70 kilograms of Radix Glycyrrhizae Preparatas, thick dose, 48 kilograms, 70 kilograms of Herba Taraxacis, 50 kilogram of ten flavor of Rhizoma Corydalis place the multi-functional extraction of Chinese medicine to get device, add 880 kg water, power mouth heat decocts twice, the boiling back keeps little boiling 145 minutes for the first time, boil to the saturating heart of medical material, for the second time keeping little boiled 60 minutes, boil to the medical material abnormal smells from the patient thin, merge decoction liquor twice, filter, be concentrated into density and be 1.5 thick extractum, simultaneously, collect the volatile oil that distributes when decocting; In thick extractum, add 35 kilograms of starch, mix homogeneously, adding distil water, after crossing 20 mesh sieves and making soft material, wet grain 70 ℃ dry down, moisture is 5.5%; Spray volatile oil on dried granule, sealing was placed 120 minutes, and behind the granulate, power mouth go into to flow 25 kilograms of lubricant Pulvis Talci are put in the mixer after the mixing, are pressed into tablet with tablet machine.

Dissolved granule is made in sugaring of the present invention, adds Mel and makes syrup, the watered pill, honeyed pill or water preparation.Avoid the food that eats:

Avoid purified saccharide, bread, cake, macaroni, milk product, caffeine, orange class fruit, Fructus Lycopersici esculenti, green pepper, soda pop, chips dip, junk food, the fried food of Shan, maror, red meat, beans, cola.Reduce the intake of salt.Processed food, junk food and the secretion of all milk product meeting stimulating mucosal are excessive, cause protein digestibility bad.The consumption of restraining Semen arachidis hypogaeae, Seem Lablab Album and Semen sojae atricolor.They contain a kind of ferment inhibitor.

Claims (2)

1, a kind of pharmaceutical composition is characterized in that being made up of following compositions and weight ratio: big Fructus Crataegi 45-50 Fructus Hordei Germinatus 45-55 Massa Medicata Fermentata 45-55 Semen phaseoli radiati 50-80 Rhizoma Atractylodis Macrocephalae 45-55 Folium Perillae 40-55 Radix Glycyrrhizae Preparata 70-80 Cortex Magnoliae Officinalis 45-55 Herba Taraxaci 60-80 Rhizoma Corydalis 45-65

2, getting the big Fructus Crataegi 45 gram Fructus Hordei Germinatus 45 gram Massa Medicata Fermentata 45 gram Semen phaseoli radiatis 50 gram Rhizoma Atractylodis Macrocephalaes 45 gram Folium Perillaes 40 gram Radix Glycyrrhizae Preparatas 70 gram Cortex Magnoliae Officinalis restrains 55 Herba Taraxacis, 60 gram Rhizoma Corydalis, 50 grams and places the Chinese medicine multi-functional extractor (the upright Chinese medicine equipment in Wuhan manufacturing company produces, model TwL-1000) in, add 700 gram water, heating decocts twice, the boiling back keeps little boiling 100 minutes for the first time, boil to the saturating heart of medical material, for the second time keeping little boiled 40 minutes, boil to the medical material abnormal smells from the patient thin, merge decoction liquor twice, filter, be concentrated into density and be 1.5 thick extractum, simultaneously, collect the volatile oil that distributes when decocting; In thick extractum, add excipient starch 20 gram, mix homogeneously, adding distil water, after crossing 16 mesh sieves and making soft material, wet grain 60 ℃ dry down, moisture is 2.5%; Spray volatile oil on dried granule, sealing was placed 100 minutes, and behind the granulate, power mouth lubricant Pulvis Talci 10 grams of going into to flow are put in the mixer after the mixing, are pressed into tablet with tablet machine.