CN101327296A - Compound Chinese medicine preparation for treating and improving insomnia and preparation method thereof - Google Patents
Compound Chinese medicine preparation for treating and improving insomnia and preparation method thereof Download PDFInfo
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- CN101327296A CN101327296A CNA2008100484907A CN200810048490A CN101327296A CN 101327296 A CN101327296 A CN 101327296A CN A2008100484907 A CNA2008100484907 A CN A2008100484907A CN 200810048490 A CN200810048490 A CN 200810048490A CN 101327296 A CN101327296 A CN 101327296A
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Abstract
The invention relates to a compound traditional Chinese medicine preparation for remedying and improving insomnia symptoms and a preparation method thereof. The compound traditional Chinese medicine preparation is made from the raw materials with the following effective constituents of sang, keel, albizzia julibrissin durazz, salvia, radix scrophulariae, oyster, baked licorice, rush, schisandra, olibanum, uncaria, polygala, cornus officinalis, Fushen, angelica, cedar seed, caulis polygoni multiflori, liriope, longan pulp and radix rehmanniae. The compound Chinese medicine preparation has the following preparation method: the raw materials are mixed in proportion, after the mixture becomes into the clear paste by being processed adding water, decocting, filtering and condensing, microcrystalline cellulose, starch, sodium carboxy methyl starch and 75 percent of ethanol are added, and then the procedures of granulating, drying, graining and packaging into the capsule are processed, and at last the medicine is made. The compound Chinese medicine preparation has the advantages of reasonable compositions, convenient usage, simple preparation process, low cost and so on, which is suitable to be used for remedying and improving the symptoms of insomnia, depression, anxiety, amnesia, neurasthenia and so on caused by various causes.
Description
Technical field
The present invention relates to medicine field, particularly relate to a kind of Chinese traditional compound medicine that is used for the treatment of and improves symptoms such as insomnia (being called for short the compound recipe SHUMIAN JIAONANG) and preparation method thereof.
Background technology
Along with the quickening day by day of modern life rhythm, the pressure of social competition allows 27% people in the world suffer from various degree sleep disorder, and according to national health tissue statistics, Chinese adult insomnia incidence rate is 38.2%, is higher than the insomnia incidence rate of developed countries.The people's that sleep disorder causes social function, the problem of spiritual aspect, even the time is long, and it can cause human organ later on, such as the obstacle of digestive system, cardiovascular system, function of immune system.Insomnia has become a serious social concern.The bad probability that not only can allow the people suffer from diseases such as hypertension, apoplexy, diabetes of sleeping increases, and because the vehicle accident that fatigue driving causes is also in rising trend in recent years.In the medicine of existing Cure for insomnia, be based on chemical drugs mostly, price is very expensive, but the general toxic and side effects of chemicals is big, bigger to other position organ stimulatings of health, and outbreak repeatedly easily, unsuitable life-time service.
The traditional Chinese medical science claims insomnia to be " being insomnia ", how by damaged by excess of seven emotions, ponders over due to overstrain or frightened cruelly or the body deficiency due to old age; Its pathogenesis is visceral dysfunction, qi-blood disharmony, yin and yang imbalance, so that the mind disturbed, mental derangement and must not sleeping.Cure this disease, should be earlier from Ben Shizhi, recuperate under medical treatment internal organs, QI and blood regulating YIN and YANG emphatically, with " tonifying for deficiency syndrome, reducing for the excess syndrome, transfer its deficiency and excess ", answer conditioning viscera, methods such as invigorating the heart and spleen, QI invigorating is relieving convulsion, restoring normal coordination between the heart and kidney, promoting blood circulation to remove obstruction in the collateral make it that internal organs are gentle, QI and blood and smooth, equilibrium between yin and yang, the mind keep house etc., then can heal also.The cardiovascular disease prevalence is the trend that rises year by year in the world in recent years, and human life and health in serious threat.
Summary of the invention
Technical problem to be solved by this invention is: provide a kind of and be used for the treatment of and improve compound recipe SHUMIAN JIAONANG because of symptoms such as insomnia that a variety of causes causes, depression, anxiety, forgetful, neurasthenias, provide technology simply to be used to prepare the method for this compound recipe SHUMIAN JIAONANG simultaneously.
The present invention solves its technical problem and adopts following technical scheme:
Compound recipe SHUMIAN JIAONANG provided by the invention, it is made the raw materials of effective components medicine and mainly consists of by weight: Radix Ginseng 20-30 part, Os Draconis 40-50 part, Cortex Albiziae 40-50 part, Radix Salviae Miltiorrhizae 40-50 part, Radix Scrophulariae 40-50 part, Concha Ostreae 40-50 part, Radix Glycyrrhizae Preparata 30-40 part, Medulla Junci 140-160 part, Fructus Schisandrae Chinensis 40-50 part, Olibanum 20-30 part, Ramulus Uncariae Cum Uncis 40-50 part, Radix Polygalae 40-50 part, Fructus Corni 40-50 part, Poria cum Radix Pini 40-50 part, Radix Angelicae Sinensis 40-50 part, Semen Platycladi 40-50 part, Caulis Polygoni Multiflori 40-50 part, Radix Ophiopogonis 40-50 part, Arillus Longan 30-40 part, Radix Rehmanniae 40-50 part.
The method of compound recipe SHUMIAN JIAONANG provided by the invention, it may further comprise the steps: earlier the above-mentioned raw materials of effective components medicine of making is mixed in proportion, the water that adds 8-12 times of weight, decoct 3 times, each 2 hours, collecting decoction, filter back gained concentrating filter liquor to clear paste, add microcrystalline Cellulose 10-20 part, starch 10-20 part, carboxymethylstach sodium 10-20 part and 75% ethanol 10-50 part again, then through granulate, dry, granulate and incapsulate operation, promptly get described compound recipe SHUMIAN JIAONANG.
The raw material that the present invention uses all can be bought from the market.The function description of each raw material is as follows:
Radix Ginseng: strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid, and calms the nerves.
Os Draconis: control the night sweat that crouches night, nocturnal emission, spermatorrhea, discharging fresh blood stool, dysentery.
Cortex Albiziae: resolving stagnation for tranquilization, promoting blood circulation and detumescence.Be used for irritability, melancholy insomnia, the lung abscess skin ulcer is swollen, falls and pounces on the pain of injury.
Radix Salviae Miltiorrhizae: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.
Radix Scrophulariae: removing heat from blood YIN nourishing, eliminating fire and detoxication.
Concha Ostreae: tranquillization with heavy prescription, the YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating.
Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.Be used for weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.
Medulla Junci: clearing heart fire, inducing diuresis for treating stranguria syndrome.Control gonorrhea, edema, dysuria, jaundice due to damp-heat, dysphoria and insomnia.
Fructus Schisandrae Chinensis: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.
Olibanum: regulating QI, to invigorate blood circulation, pain relieving chases after poison.
Ramulus Uncariae Cum Uncis: heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.
Radix Polygalae: the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm detumescence.
Fructus Corni: liver and kidney tonifying, essence astringing and desertion stemming.
Poria cum Radix Pini: mind calming, calm the nerves diuretic.Control the palpitation with fear of having a guilty conscience, forgetful, insomnia, infantile convulsion, dysuria.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Semen Platycladi: tranquilizing by nourishing the heart, loosening bowel to relieve constipation.
Caulis Polygoni Multiflori:: nourish heart, calm the nerves, collateral dredging dispels the wind.
Radix Ophiopogonis: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.
Arillus Longan: heart tonifying and tranquilizing, strengthening the spleen nourishes blood.
The Radix Rehmanniae: control fever due to yin deficiency, quench one's thirst, spit blood, frequent fetal movement, the moon is hindered constipation.
Microcrystalline Cellulose: be diluent, play the dilution tablet.
Starch: be diluent, play the dilution tablet
Carboxymethylstach sodium: be lubricant, work to strengthen the lubricity of tablet.
75% ethanol: be adhesive, play and strengthen the effect of tablet viscosity.
But this medicine resolving stagnation for tranquilization, dispelling wind and relieving convulsion, promoting blood circulation and detumescence is enriched blood and is invigorated blood circulation.Various raw materials are compatibility together, can synergism, and complementation is helped each other, and the property of medicine of each flavor medicine is all performed to and extremely, can effectively treat insomnia, depression, anxiety, neurasthenia that a variety of causes causes.
The present invention compared with prior art mainly contains following advantage:
One. prescription is reasonable: meet traditional Chinese medical science combination formula theory, and select YAOJING, used primary raw material is a natural plants Chinese medicine, therefore has no side effect, and takes safety.
They are two years old. are suitable for wide: except effectively treating various common insomnias, symptoms such as the depression that has multiple reason to cause, anxiety, forgetful, neurasthenia are all had better therapeutic effect.
They are three years old. and make capsule and make it be different from traditional form of Chinese drug, use more convenient.
They are four years old. and processing technology is simple, and cost is low.
The specific embodiment
The invention will be further described below in conjunction with embodiment, but do not limit the present invention.
Embodiment 1:
By weight, following raw material is mixed: 20 parts of Radix Ginsengs, 45 parts of Os Draconis, 45 parts of Cortex Albiziaes, 45 parts of Radix Salviae Miltiorrhizaes, 45 parts of Radix Scrophulariaes, 45 parts of Concha Ostreaes, 45 parts of Radix Glycyrrhizae Preparatas, 150 parts of Medulla Juncies, 45 parts of Fructus Schisandrae Chinensis, 27 parts of Olibanums, 45 parts of Ramulus Uncariae Cum Uncis, 45 parts of Radix Polygalaes, 45 parts of Fructus Corni, 45 parts of Poria cum Radix Pinis, 45 parts of Radix Angelicae Sinensis, 45 parts of Semen Platycladi, 45 parts of Caulis Polygoni Multiflori, 45 parts of Radix Ophiopogonis, 36 parts of Arillus Longans, 45 parts in the Radix Rehmanniae.
Preparation method may further comprise the steps: get described raw material, be mixed in proportion, add 10 times water, decoct 3 times, each 2h, collecting decoction filters, and filtrate is concentrated into clear paste, and relative density is 1.2, add 15 parts of microcrystalline Cellulose, 15 parts of starch, 15 parts of carboxymethylstach sodium, 30 parts of 75% ethanol.Wave granulator and granulate, drying, granulate incapsulates, promptly.
Embodiment 2:
By weight, following raw material is mixed: 30 parts of Radix Ginsengs, 50 parts of Os Draconis, 50 parts of Cortex Albiziaes, 50 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Scrophulariaes, 50 parts of Concha Ostreaes, 50 parts of Radix Glycyrrhizae Preparatas, 160 parts of Medulla Juncies, 50 parts of Fructus Schisandrae Chinensis, 30 parts of Olibanums, 50 parts of Ramulus Uncariae Cum Uncis, 50 parts of Radix Polygalaes, 50 parts of Fructus Corni, 50 parts of Poria cum Radix Pinis, 50 parts of Radix Angelicae Sinensis, 50 parts of Semen Platycladi, 50 parts of Caulis Polygoni Multiflori, 50 parts of Radix Ophiopogonis,, 50 parts of Arillus Longans, 50 parts in the Radix Rehmanniae.
Preparation method may further comprise the steps: get described raw material, be mixed in proportion, add 12 times water, decoct 3 times, each 3h, collecting decoction filters, and filtrate is concentrated into clear paste, and relative density is 1.35, add 20 parts of microcrystalline Cellulose, 20 parts of starch, 20 parts of carboxymethylstach sodium, 50 parts of 75% ethanol.Wave granulator and granulate, drying, granulate incapsulates, promptly.
Embodiment 3:
By weight, following raw material is mixed: 25 parts of Radix Ginsengs, 40 parts of Os Draconis, 40 parts of Cortex Albiziaes, 40 parts of Radix Salviae Miltiorrhizaes, 40 parts of Radix Scrophulariaes, 40 parts of Concha Ostreaes, 30 parts of Radix Glycyrrhizae Preparatas, 140 parts of Medulla Juncies, 45 parts of Fructus Schisandrae Chinensis, 25 parts of Olibanums, 45 parts of Ramulus Uncariae Cum Uncis, 45 parts of Radix Polygalaes, 45 parts of Fructus Corni, 45 parts of Poria cum Radix Pinis, 45 parts of Radix Angelicae Sinensis, 45 parts of Semen Platycladi, 45 parts of Caulis Polygoni Multiflori, 45 parts of Radix Ophiopogonis, 35 parts of Arillus Longans, 45 parts in the Radix Rehmanniae.
Preparation method may further comprise the steps: get described raw material, be mixed in proportion, add 9 times water, decoct 3 times, each 3h, collecting decoction filters, and filtrate is concentrated into clear paste, and relative density is 1.15, add 10 parts of microcrystalline Cellulose, 15 parts of starch, 15 parts of carboxymethylstach sodium, 30 parts of 75% ethanol.Wave granulator and granulate, drying, granulate incapsulates, promptly.
Embodiment 4:
20 parts of Radix Ginsengs, 45 parts of Os Draconis, 45 parts of Cortex Albiziaes, 45 parts of Radix Salviae Miltiorrhizaes, 45 parts of Radix Scrophulariaes, 45 parts of Concha Ostreaes, 45 parts of Radix Glycyrrhizae Preparatas, 150 parts of Medulla Juncies, 40 parts of Fructus Schisandrae Chinensis, 20 parts of Olibanums, 40 parts of Ramulus Uncariae Cum Uncis, 40 parts of Radix Polygalaes, 40 parts of Fructus Corni, 40 parts of Poria cum Radix Pinis, 40 parts of Radix Angelicae Sinensis, 40 parts of Semen Platycladi, 40 parts of Caulis Polygoni Multiflori, 40 parts of Radix Ophiopogonis, 30 parts of Arillus Longans, 40 parts in the Radix Rehmanniae.
Preparation method may further comprise the steps: get described raw material, be mixed in proportion, add 8 times water, decoct 3 times, each 2h, collecting decoction filters, and filtrate is concentrated into clear paste, and relative density is 1.0, add 20 parts of microcrystalline Cellulose, 10 parts of starch, 10 parts of carboxymethylstach sodium, 10 parts of 75% ethanol.Wave granulator and granulate, drying, granulate incapsulates, promptly.
Claims (7)
1. a Chinese traditional compound medicine that is used for the treatment of and improves insomnia is characterized in that making the raw materials of effective components medicine and mainly consists of by weight: Radix Ginseng 20-30 part, Os Draconis 40-50 part, Cortex Albiziae 40-50 part, Radix Salviae Miltiorrhizae 40-50 part, Radix Scrophulariae 40-50 part, Concha Ostreae 40-50 part, Radix Glycyrrhizae Preparata 30-40 part, Medulla Junci 140-160 part, Fructus Schisandrae Chinensis 40-50 part, Olibanum 20-30 part, Ramulus Uncariae Cum Uncis 40-50 part, Radix Polygalae 40-50 part, Fructus Corni 40-50 part, Poria cum Radix Pini 40-50 part, Radix Angelicae Sinensis 40-50 part, Semen Platycladi 40-50 part, Caulis Polygoni Multiflori 40-50 part, Radix Ophiopogonis 40-50 part, Arillus Longan 30-40 part, Radix Rehmanniae 40-50 part.
2. Chinese traditional compound medicine according to claim 1 is characterized in that the raw material of following weight parts in addition: microcrystalline Cellulose 10-20 part, starch 10-20 part, carboxymethylstach sodium 10-20 part, 75% ethanol 10-50 part.
3. Chinese traditional compound medicine according to claim 1 is characterized in that being made up of the raw material of following weight portion: 20 parts of Radix Ginsengs, 45 parts of Os Draconis, 45 parts of Cortex Albiziaes, 45 parts of Radix Salviae Miltiorrhizaes, 45 parts of Radix Scrophulariaes, 45 parts of Concha Ostreaes, 45 parts of Radix Glycyrrhizae Preparatas, 150 parts of Medulla Juncies, 45 parts of Fructus Schisandrae Chinensis, 27 parts of Olibanums, 45 parts of Ramulus Uncariae Cum Uncis, 45 parts of Radix Polygalaes, 45 parts of Fructus Corni, 45 parts of Poria cum Radix Pinis, 45 parts of Radix Angelicae Sinensis, 45 parts of Semen Platycladi, 45 parts of Caulis Polygoni Multiflori, 45 parts of Radix Ophiopogonis, 36 parts of Arillus Longans, 45 parts in the Radix Rehmanniae, 15 parts of microcrystalline Cellulose, 15 parts of starch, 15 parts of carboxymethylstach sodium, 30 parts of 75% ethanol.
4. preparation method that is used for the treatment of and improves the Chinese traditional compound medicine of insomnia, it is characterized in that may further comprise the steps: will make the raw materials of effective components medicine earlier and be mixed in proportion, the water that adds 8-12 times of weight, decoct 3 times, each 2 hours, collecting decoction, filter back gained concentrating filter liquor to clear paste, add microcrystalline Cellulose 10-20 part, starch 10-20 part, carboxymethylstach sodium 10-20 part and 75% ethanol 10-50 part again, then through granulate, dry, granulate and incapsulate operation, promptly get described Chinese traditional compound medicine;
Making the raw materials of effective components medicine mainly consists of by weight: Radix Ginseng 20-30 part, Os Draconis 40-50 part, Cortex Albiziae 40-50 part, Radix Salviae Miltiorrhizae 40-50 part, Radix Scrophulariae 40-50 part, Concha Ostreae 40-50 part, Radix Glycyrrhizae Preparata 30-40 part, Medulla Junci 140-160 part, Fructus Schisandrae Chinensis 40-50 part, Olibanum 20-30 part, Ramulus Uncariae Cum Uncis 40-50 part, Radix Polygalae 40-50 part, 40 50 parts of Fructus Corni, Poria cum Radix Pini 40-50 part, Radix Angelicae Sinensis 40-50 part, Semen Platycladi 40-50 part, Caulis Polygoni Multiflori 40-50 part, Radix Ophiopogonis 40-50 part, Arillus Longan 30-40 part, Radix Rehmanniae 40-50 part.
5. the preparation method of Chinese traditional compound medicine according to claim 4 is characterized in that being made up of the raw material of following weight portion: 20 parts of Radix Ginsengs, 45 parts of Os Draconis, 45 parts of Cortex Albiziaes, 45 parts of Radix Salviae Miltiorrhizaes, 45 parts of Radix Scrophulariaes, 45 parts of Concha Ostreaes, 45 parts of Radix Glycyrrhizae Preparatas, 150 parts of Medulla Juncies, 45 parts of Fructus Schisandrae Chinensis, 27 parts of Olibanums, 45 parts of Ramulus Uncariae Cum Uncis, 45 parts of Radix Polygalaes, 45 parts of Fructus Corni, 45 parts of Poria cum Radix Pinis, 45 parts of Radix Angelicae Sinensis, 45 parts of Semen Platycladi, 45 parts of Caulis Polygoni Multiflori, 45 parts of Radix Ophiopogonis, 36 parts of Arillus Longans, 45 parts in the Radix Rehmanniae, 15 parts of microcrystalline Cellulose, 15 parts of starch, 15 parts of carboxymethylstach sodium, 30 parts of 75% ethanol.
6. the preparation method of Chinese traditional compound medicine according to claim 4, it is characterized in that: the relative density of described clear paste is 1.0~1.35.
7. the preparation method of Chinese traditional compound medicine according to claim 4 is characterized in that: granulate with waving granulator.
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CN103550701A (en) * | 2013-11-06 | 2014-02-05 | 葛晓云 | Traditional Chinese medicinal capsules for treating insomnia |
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