CN103127297A - Traditional Chinese medicine compound for treatment of fear neuroses and preparation method thereof - Google Patents

Traditional Chinese medicine compound for treatment of fear neuroses and preparation method thereof Download PDF

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CN103127297A
CN103127297A CN201310094430XA CN201310094430A CN103127297A CN 103127297 A CN103127297 A CN 103127297A CN 201310094430X A CN201310094430X A CN 201310094430XA CN 201310094430 A CN201310094430 A CN 201310094430A CN 103127297 A CN103127297 A CN 103127297A
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李艳
张敏
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Abstract

The invention discloses a traditional Chinese medicine compound for treatment of fear neuroses and a preparation method thereof. The traditional Chinese medicine compound comprises the following components according to certain weight ratio: poria with hostwood, spina date seed, polygala tenuifolia, platycladi seed, schisandra chinensis, processed fleece-flower root, coptis root, dried rehmannia root, angelica sinensis, Chinese rose, concha haliotidis, cinnabar, raw dragon bone and honey-fried licorice root. The traditional Chinese medicine compound has the effects of nourishing the liver and tonifying the kidney and calming the nerves, and can treat the fear neuroses effectively.

Description

A kind of Chinese medicine composition for the treatment of phobic neurosis and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of phobic neurosis and preparation method thereof.
Background technology
Phobic neurosis, namely phobia, phobia, be a kind of too and unreasonably to fear extraneous object or situation as main neurosis.Patient knows perfectly well and there is no need, but still can not prevent frightened outbreak, during frightened outbreak often with significant anxiety and autonomic nerve symptom.Patient does one's utmost to avoid object or the situation of fearing, or goes to stand with fear.Doctor trained in Western medicine thinks that the cause of disease is inherited genetic factors, predisposing factor, physiologic factor and socio-psychological factors.Drug therapy is mainly for the caused anxiety of phobia and depressive emotion, can alleviate terrified symptom, but withdrawal has higher relapse rate and easily produces drug dependence.The traditional Chinese medical science is referred to as " probably card ", thinks that this disease is many because of damaged by excess of seven emotions, undermines due to the Liver and kidney heart and gallbladder.Phobia is in the majority with deficiency syndrome, is the disease of asthenia of essence and blood.The major lesions position is at liver, kidney, the heart, gallbladder.Timidness due to deficiency of the heart, blood stored in the liver, its property master liter, the master considers, and gallbladder is the fu-organ that contains refined juice, main resolution.Liver and gall timidness due to deficiency of QI liver loses the duty of hiding soul, as takes fright, the mind fall, and QI and blood is disorderly contrary, and causes fear.As " Plain Questions lift pain opinion " day: " frightened refreshing lean on without institute, god's nothing is returned, and the worry nothing is decided, therefore disturbance of QI." deficiency of kidney-essence, natural endowment is not enough, and kidney yin is deficient; Prolonged illness day after tomorrow consumption of essence, kidney essense consumption wound causes damage of kidney-YIN, asthenia of essence and blood.Kidney storing essence is that probably deficiency of kidney-essence causes the brains deficiency in will, therefore cause probably card outbreak.Chinese medicine adopts the dialectical method that treats, determined curative effect, and double taking stopgap measures originally overcomes the dependent shortcoming of Western medicine, and be safe and reliable, has no side effect.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition, it is good, rapid-action that this Chinese medicine composition has a therapeutic effect for the treatment phobic neurosis, the characteristics that have no side effect.
The present invention selects Poria cum Radix Pini, Semen Ziziphi Spinosae, Radix Polygalae, Semen Platycladi, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Coptidis, Radix Rehmanniae, Radix Angelicae Sinensis, Flos Rosae Chinensis, Concha Haliotidis, Cinnabaris, Os Draconis, Radix Glycyrrhizae Preparata to make up, make each efficacy of drugs produce synergism these drug regimens, make it to have nourishing liver, invigorating kidney, the effect of calming the nerves and calming the frightened, thus phobic neurosis can effectively be treated.
The effect of Chinese medicine of the present invention:
Wherein:
Poria cum Radix Pini: for (Poria) in the middle of poria cocos sclerotium entertains Radix Pini massonianae or fine core person's part.Nature and flavor are sweet, light, and are flat.GUIXIN, spleen channel.Function: mind tranquilizing and the heart calming, diuretic.Poria cum Radix Pini's decoct can make the people enter quiet sleepy state, and sedation is arranged." property of medicine opinion ": main infantile convulsion, tranquilizing the mind is mended tired; Main acute pain in the epigastrium is hard full, and small intestinal is unfavorable.
Semen Ziziphi Spinosae: be the seed of Rhamnaceae plant Ziziphi Spinosae.Nature and flavor are sweet, sour, and are flat.The GUIXIN warp; Spleen channel; Liver Channel; Gallbladder meridian.Effect: nourishing the liver, mind calming is calmed the nerves, arresting sweating.The calmness of Semen Ziziphi Spinosae water solubility extract, hypnosis, anticonvulsant action.
Radix Polygalae: be the dry root of milk wort Radix Polygalae Polygala tenuifolia Willd. or ovum leaf Radix Polygalae Polygala sibirica L..Nature and flavor are bitter, hot, tepor.GUIXIN, kidney, lung meridian.Effect: the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, detumescence.The natural prerequisite medicine that contains TMCA in the Radix Polygalae water extract plays sedation.
Semen Platycladi: be the dry mature kernal of Cupressaceae plant Cacumen Platycladi Platycladus orientalis (L.) Franco.Nature and flavor are sweet, and are flat.GUIXIN, kidney, large intestine channel.Effect: tranquilizing by nourishing the heart, loosening bowel to relieve constipation.Semen Platycladi has calmness, syngignoscism.Shennong's Herbal: " cypress is real, and sweet in the mouth is flat, main palpitation with fear, and settling five organs, QI invigorating, except rheumatism numbness, clothes make us moist, beauty, normal hearing and eyesight for a long time.”
Fructus Schisandrae Chinensis: be the dry mature fruit of magnoliaceae schisandra Schisandra chinensis (Turcz.) Baill..The nature and flavor temperature; Sour, sweet; Return lung, the heart, kidney channel.Effect: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Fructus Schisandrae Chinensis has obvious sedation and good sedative action to the central nervous system.
Radix Polygoni Multiflori Preparata: be the dried root of polygonum multiflorum thunb Polygonum multiflorum Thunb..Nature and flavor are bitter, sweet, puckery, tepor.Return liver, kidney channel.Effect: nourishing the blood and yin; Loosening bowel to relieve constipation.But Radix Polygoni Multiflori Preparata extract concentration dependent ground suppresses interleukin and nitric oxide production generation, thus the performance neuroprotective.
Rhizoma Coptidis: be the dry rhizome of cohosh Rhizoma Coptidis (Coptis chinensis Franch.), Coptis deltoidea C.Y.Cheng et Hsiao (Coptis deltoidea C. Y. Cheng et Hsiao) and Coptis Teeta Wall (Coptis teeta Wall.).Nature and flavor are bitter, and are cold, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication." Japan hanako materia medica ": control five kinds of strain and seven kinds of impairment, QI invigorating is stopped cardiac and abdominal pain, palpitation with fear, agitation, profit cardiopulmonary, is put on flesh, stops blooding and the skin ulcer scabies, night sweat, day hot disease of row.Gaster Sus domestica steams for ball, controls children's's infantile malnutrition gas.
Radix Rehmanniae: be the root of dicotyledon medicine scrophulariaceae rehmannia glutinosa plant or bosom celebrating Radix Rehmanniae.Nature and flavor are sweet, and hardship is cool.Enter the heart, liver, kidney channel.Effect: heat clearing away is nourished blood, the YIN nourishing of promoting the production of body fluid.Radix Rehmanniae is joined Cortex Phellodendri, replenishing YIN and removing heat; Radix Rehmanniae has obvious sedation, and its site of action is at cerebral cortex, and its aqueous extract can suppress autonomic activities, and can strengthen the syngignoscism of HD pentobarbital sodium and penthiobarbital, also can resist the excitation of caffeine and sodium benzoate simultaneously.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor are sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Effect: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Radix Angelicae Sinensis volatile oil has the effects such as calmness, hypnosis, analgesia, anesthesia to the central nervous system.
Flos Rosae Chinensis: claim again " Fols Rosae ", Rosaceae for spending middle queen.Evergreen or half evergreen low brushwood, opening the how red color ﹐ idol of colored ﹐ four seasons has white color ﹐ to can be used as ornamental plant, can be used as medicinal plants.Nature and flavor are sweet, temperature.Enter Liver Channel.Effect: promoting blood circulation and detumescence, eliminating inflammation and expelling toxin.
Concha Haliotidis: be the shell of Bao Ke animal Haliotis diversicolor, haliotis discus hannai Ino, ear Bao, sheep Bao etc.Nature and flavor are salty, cold.Enter liver, kidney channel.Effect: calming liver and clearing heat, removing nebula makes eye bright." Shandong Chinese herbal medicine handbook: the town liver, make eye bright, control dizzy.
Cinnabaris: claiming again cinnabar, cinnabar, Chi Dan, hydrargyrum sand, is cinnabar (chemical name: natural crystal HgS).Nature and flavor are sweet, and are cool; Poisonous.The GUIXIN warp.Effect: calm the nerves, arresting convulsion makes eye bright, detoxifcation.Cinnabaris can reduce the irritability of brain nervus centralis, and sedative-hypnotic property is arranged." herbal classic ": support spirit, the peace soul, QI invigorating makes eye bright.
Os Draconis: for ancient times mammal as if the fossil of the skeleton of class, rhinoceros class, Hippocampal cortex etc.Nature and flavor are sweet, puckery, flat.Enter the heart, liver, kidney channel.Effect: subduing hyperactive YANG to ease mental disorders.Os Draconis mainly contain calcium carbonate, calcium phosphate, and a small amount of ferrum, magnesium, aluminum, potassium, sodium, chlorine, sulfate radical etc. have the effect of calmness, convergence, astringent or styptic treatment for spontaneous sweating, antidiarrheal.
Radix Glycyrrhizae Preparata: be the dry root and rhizome of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Radix Glycyrrhizae Preparata is that the honey of Radix Glycyrrhizae is smoked processed goods.Nature and flavor are sweet, and are flat.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery.
Medicine material consumption of the present invention is groped to sum up to draw through the inventor in a large number, and each raw material consumption is for all to have curative effect preferably in the following weight parts scope: Poria cum Radix Pini 15-25 part, Semen Ziziphi Spinosae 25-35 part, Radix Polygalae 19-29 part, Semen Platycladi 10-20 part, Fructus Schisandrae Chinensis 7-17 part, Radix Polygoni Multiflori Preparata 19-29 part, Rhizoma Coptidis 3-9 part, Radix Rehmanniae 25-35 part, Radix Angelicae Sinensis 13-23 part, Flos Rosae Chinensis 7-17 part, Concha Haliotidis 25-35 part, Cinnabaris 1-3 part, Os Draconis 25-35 part, Radix Glycyrrhizae Preparata 6-12 part.
Wherein be preferably: 20 parts of Poria cum Radix Pinis, 30 parts of Semen Ziziphi Spinosaes, 24 parts of Radix Polygalaes, 15 parts of Semen Platycladi, 12 parts of Fructus Schisandrae Chinensis, 24 parts of Radix Polygoni Multiflori Preparata, 6 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae, 18 parts of Radix Angelicae Sinensis, 12 parts of Flos Rosae Chinensiss, 30 parts of Concha Haliotidis, 2 parts, Cinnabaris, 30 parts of Os Draconis, 9 parts of Radix Glycyrrhizae Preparatas.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into decoction.
Step 1, at first first put into container according to weight proportion weighing Concha Haliotidis, Os Draconis and boiled 20 minutes;
Step 2, then put into the step 1 container according to weight proportion weighing Poria cum Radix Pini, Semen Ziziphi Spinosae, Radix Polygalae, Semen Platycladi, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Coptidis, Radix Rehmanniae, Radix Angelicae Sinensis, Flos Rosae Chinensis, Radix Glycyrrhizae Preparata and fry in shallow oil again and got final product in 25-30 minute;
Step 3, directly take after mixing it with hot water according to weight proportion weighing Cinnabaris at last;
Medicine of the present invention has nourishing liver, invigorating kidney, and the effects such as arresting convulsion of calming the nerves, and therapeutic effect is good, rapid-action, has no side effect according to clinical 60 routine patients are observed statistics, are used 86%, two of one of the medicine of the present invention total effective rate course for the treatment of total effective rate course for the treatment of 95%.
The specific embodiment
Embodiment one, 15 parts of Poria cum Radix Pinis, 25 parts of Semen Ziziphi Spinosaes, 19 parts of Radix Polygalaes, 10 parts of Semen Platycladi, 7 parts of Fructus Schisandrae Chinensis, 19 parts of Radix Polygoni Multiflori Preparata, 3 parts of Rhizoma Coptidis, 25 parts of Radix Rehmanniae, 13 parts of Radix Angelicae Sinensis, 7 parts of Flos Rosae Chinensiss, 25 parts of Concha Haliotidis, 1 part, Cinnabaris, 25 parts of Os Draconis, 6 parts of Radix Glycyrrhizae Preparatas.
Embodiment two, 20 parts of Poria cum Radix Pinis, 30 parts of Semen Ziziphi Spinosaes, 24 parts of Radix Polygalaes, 15 parts of Semen Platycladi, 12 parts of Fructus Schisandrae Chinensis, 24 parts of Radix Polygoni Multiflori Preparata, 6 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae, 18 parts of Radix Angelicae Sinensis, 12 parts of Flos Rosae Chinensiss, 30 parts of Concha Haliotidis, 2 parts, Cinnabaris, 30 parts of Os Draconis, 9 parts of Radix Glycyrrhizae Preparatas.
Embodiment three, 25 parts of Poria cum Radix Pinis, 35 parts of Semen Ziziphi Spinosaes, 29 parts of Radix Polygalaes, 20 parts of Semen Platycladi, 17 parts of Fructus Schisandrae Chinensis, 29 parts of Radix Polygoni Multiflori Preparata, 9 parts of Rhizoma Coptidis, 35 parts of Radix Rehmanniae, 23 parts of Radix Angelicae Sinensis, 17 parts of Flos Rosae Chinensiss, 35 parts of Concha Haliotidis, 3 parts, Cinnabaris, 35 parts of Os Draconis, 12 parts of Radix Glycyrrhizae Preparatas.
The below is the clinical statistics data that the patient uses medicine of the present invention:
One, physical data
Accept patient's totally 60 examples for medical treatment, male's 19 examples wherein, women's 41 examples, M-F 0.5:1,25 years old mean age.
Two, diagnostic criteria
1, meet neurosal diagnostic criteria.
2, take fear as main, need meet following 4:
1. some object or situation are had strong fear, frightened degree and actual danger are unbecoming;
Anxiety and autonomic nerve symptom are arranged when 2. showing effect;
3. the elusive behavior that has repeatedly or continue;
4. it is frightened undue, unreasonable to know, or unnecessary, but uncontrollable;
3, to the avoidance of frightened sight and things must be or be once outstanding symptom;
4, get rid of anxiety neurosis, Split disease, hypochondria.
Three, Therapeutic Method
According to drug weight proportioning of the present invention, weighting raw materials (daily dose), decocting, filter and remove residue services once sooner or later, and 10 is a course for the treatment of.
Four, efficacy assessment standard
Cure: transference cure.
Take a turn for the better: sx↓, attack times reduces, and the intermission extends.
Do not heal: cardinal symptom is without change.
Five, therapeutic outcome statistics
Figure 201310094430X100002DEST_PATH_IMAGE001
Wherein: total effective rate=cure rate+improvement rate
Model case and curative effect:
Case one, Liu, the female, 25 years old age, phobia, serious over the past two years, dare not associate with the people, dare not contact with stranger's sight, fear, anxiety, alarmed, have a strong impact on live and work.The patient takes Chinese medicine of the present invention after course for the treatment of, and symptom all disappears, recovery from illness.
Case two, Chen, female, patient age 27 years old.Phobia is feared others expression in the eyes, and nervous, hands is trembled, and escapes doings, has a dinner party together and picks up chopsticks, and when hold wineglass, hands is just trembled, and heart beating is very fast, and present hands also has slight shake in not frightened, becomes thin, and emotion is very low.The patient takes Chinese medicine of the present invention after two courses for the treatment of, and symptom disappears substantially, takes a turn for the better.
Case three, high certain, man, 30 years old.Have a delicate constitution since the childhood, timid, because dying to go back home, grandmother hastens home for the funeral the year before, and the first time in one's life is seen the dead person, situation is at that time felt deeply feared, as long as nowadays there is the people to mention " dead person " two words, just shivers convulsively, and gallbladder is quivered unbearably.The patient takes Chinese medicine of the present invention after two courses for the treatment of, and symptom is obviously improved.

Claims (3)

1. Chinese medicine composition for the treatment of phobic neurosis, it is characterized in that, this Chinese medicine composition is the ingredients by following weight portion: Poria cum Radix Pini 15-25 part, Semen Ziziphi Spinosae 25-35 part, Radix Polygalae 19-29 part, Semen Platycladi 10-20 part, Fructus Schisandrae Chinensis 7-17 part, Radix Polygoni Multiflori Preparata 19-29 part, Rhizoma Coptidis 3-9 part, Radix Rehmanniae 25-35 part, Radix Angelicae Sinensis 13-23 part, Flos Rosae Chinensis 7-17 part, Concha Haliotidis 25-35 part, Cinnabaris 1-3 part, Os Draconis 25-35 part, Radix Glycyrrhizae Preparata 6-12 part.
2. the Chinese medicine composition for the treatment of phobic neurosis described according to claims 1, it is characterized in that, by the ingredients of following weight portion: 20 parts of Poria cum Radix Pinis, 30 parts of Semen Ziziphi Spinosaes, 24 parts of Radix Polygalaes, 15 parts of Semen Platycladi, 12 parts of Fructus Schisandrae Chinensis, 24 parts of Radix Polygoni Multiflori Preparata, 6 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae, 18 parts of Radix Angelicae Sinensis, 12 parts of Flos Rosae Chinensiss, 30 parts of Concha Haliotidis, 2 parts, Cinnabaris, 30 parts of Os Draconis, 9 parts of Radix Glycyrrhizae Preparatas.
3. according to the preparation method of the Chinese medicine composition of claims 1 or 2 described treatment phobic neurosises, it is characterized in that: step 1, at first first put into container according to weight proportion weighing Concha Haliotidis, Os Draconis and boiled 20 minutes; Step 2, then put into the step 1 container according to weight proportion weighing Poria cum Radix Pini, Semen Ziziphi Spinosae, Radix Polygalae, Semen Platycladi, Fructus Schisandrae Chinensis, Radix Polygoni Multiflori Preparata, Rhizoma Coptidis, Radix Rehmanniae, Radix Angelicae Sinensis, Flos Rosae Chinensis, Radix Glycyrrhizae Preparata and fry in shallow oil again and got final product in 25-30 minute; Step 3, directly take after mixing it with hot water according to weight proportion weighing Cinnabaris at last.
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CN103705628B (en) * 2013-12-30 2015-06-10 田生华 Traditional Chinese medicinal composition for treating palpitation and insomnia and dreamful sleep and preparation method thereof

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Application publication date: 20130605