CN101327231B - Chinese medicinal composition for treating psoriasis - Google Patents
Chinese medicinal composition for treating psoriasis Download PDFInfo
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- CN101327231B CN101327231B CN2008100171160A CN200810017116A CN101327231B CN 101327231 B CN101327231 B CN 101327231B CN 2008100171160 A CN2008100171160 A CN 2008100171160A CN 200810017116 A CN200810017116 A CN 200810017116A CN 101327231 B CN101327231 B CN 101327231B
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Abstract
The invention relates to a traditional Chinese medicine composition for treating psoriasis, in particular to a traditional Chinese medicine composition for treating recurrent psoriasis. The main characteristic is to adopt fir oleoresin, cypress resin crystal, shrubalthea bark, pine nut oil, angelica dahurica and nutgall as raw meterials to prepare paste and atomizing inhalant; aiming at the characteristic of the high recurrence rate of psoriasis, following the theory of traditional Chinese medicine, taking the principles of strengthening resistance and solidifying health, addressing both the symptoms and root causes, removing pathogenic heat from blood, killing insect and relieving itching, dissipating bruise and detoxicating, the resistance of the sufferer to the psoriasis is enhanced through improving immunity of the body, the psoriasis will not recur after being healed.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, the psoriasic Chinese medicine composition of especially a kind of treatment.
Background technology
Psoriasis is " psoriasis " again, is a kind of common chronic inflammatory disease dermatoses, has the characteristics of intractable and recurrent, its skin lesion feature is to be covered with the silvery white squama of multilamellar on red pimple or the speckle, obvious seasonal is arranged, and the most of patients state of an illness increased the weight of in spring and winter, and alleviate summer.Whole nation total prevalence rate is 0.72 ‰, and the male is more than the women, and the north is more than south, and the city is higher than the rural area.Just send out an age male and be 20-39 year, the women is maximum for 15-39 year.Sickness rate is on the rise over past ten years.Though psoriasis does not directly influence life, but healthy and physical and mental health are had a direct impact.Many young boys and girls psoriatics are arranged, and the flesh table is ashamed of exposing, and directly influences attractive in appearancely, and more painful is to cause love to be broken.Psoriasis is outbreak repeatedly all the year round, and the course of disease is delayed with the passing of time hematozemia wound essence, failure of skin and muscle to be nourished, and uninteresting pruritus, health is wrecked in the insomnia of overtaxing one's nerves.If treatment is bad, disorderly seek medical advice and abuse medicine, not only disease is not cured, on the contrary health is caused direct poisoning, and outbreak is more serious repeatedly, directly injures healthy.The delay recurrence increases the weight of year by year, and desquamation blood stasis, pruritus due to dryness bring great misery to body and mind unbearably.
The medicine for external use commonly used for the treatment of this disease clinically is the auspicious pine of piperazine, three nine-day periods after the winter solstice dermatitis equality, but often cure the symptoms, not the disease; Oral medicine has cortisone, chlorphenamine, vitamin c and corticosteroids medicine.But because of psoriasis morbidity has obvious seasonal, patient's course of disease length to be in a bad way and recurrence easily, oral medicine need continue to take and side effect big, patient body is caused further infringement.
Summary of the invention
Technical problem to be solved by this invention is the deficiency at above-mentioned treatment psoriasis medicine, a kind for the treatment of both the principal and secondary aspects of a disease is provided, strong drug action and Chinese medicine composition of having no side effect and preparation method thereof, especially a kind of Chinese medicine composition for the treatment of the recurrent psoriasis, playing tinea, eczema ulcer and seborrheic keratosis.The present invention includes medicine for external use and oral medicine.
The present invention follows the traditional theory of the traditional Chinese medical science, is principle with strengthening the body resistance, clearing away heat and cooling blood, killing parasites for relieving itching, dissipating blood stasis detoxifcation, strengthens the patient to psoriasic resistance by improving body immunity.
Choice of drug Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil of the present invention, Resina Cupressi resin crystal, the Cortex Hibisci powder, propolis, Semen pini koraiensis oil, Radix Angelicae Dahuricae powder and Chinese Gall make up.The externally used paste of these drug regimen preparations is had quickly-healing skin lesion and keratinized tissue, repair the effect of skin self-healing function.
Wherein select Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil for use, because its acrid in the mouth, slightly warm in nature, but wind-expelling pain-stopping, dissipating blood stasis hemostasis are used for the treatment of allergic dermatitis and repair the damaged skin tissue.
Resina Cupressi resin crystal: property is flat, and puckery is light, and main effect is for the heating of easing pain, separate, except that dampness.
Cortex Hibisci: sweet in the mouth, slightly warm in nature, but clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, external can be controlled eczema tinea corporis and tinea pedis.
Propolis: acrid in the mouth, slightly warm in nature can soften keratinized tissue, anti-inflammatory and antalgic, and the regenerated effect of the psoriasis histiocyte of promotion is arranged.
Semen pini koraiensis oil: sweet in the mouth, slightly warm in nature can be tonified Qi of the kidney, enriching blood for moistening the intestine, and the effect of [Japan hanako materia medica] record Semen pini koraiensis be " by a migratory arthralgia cold, the empty weak breath of winning, tonifying for the deficiency moistens skin, fertile the five internal organs ", with improving patient's immunity in the present invention.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature, return lung stomach warp, but clearing away heat and cooling blood, expelling wind and cold, understand things pain-stopping, the pus toxin expelling that disappears are used to control ulcer sores, skin dampness, scabies.
Galla Chinensis: sour-puckery flavor, cold in nature, return lung, large intestine, kidney channel, the pathogenic fire reducing of can astringing the lung, relieving diarrhea with astringents, arresting sweating hemostasis, removing dampness are held back skin ulcer, are used for the treatment of carbuncle sore tumefacting virus, Skin wet and rotten.
With the Chinese medicine ointment of this Six-element medicine combined preparation, in removing heat from blood, detoxifcation, dissipating blood stasis, can tonify Qi of the kidney again, the large intestines that nourish blood treating the psoriasic internal organs that are unlikely to simultaneously to damage, make drug effect more firm, comprehensive, thorough.
Can also add vinegar in the crude drug of the present invention, because of its sour in the mouth, property is flat, returns the stomach Liver Channel, has digesting and appetizing, loose congestion and antidotal effect.
The component of medicine of the present invention all has curative effect in following amount ranges: Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 10-30g, Resina Cupressi resin crystal 50-80g, Cortex Hibisci 5-10g, propolis 40-60g, Semen pini koraiensis oil 0.3-1.5g, Radix Angelicae Dahuricae 1-6g, Galla Chinensis 20-30g
Be preferably:
Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 20g, Resina Cupressi resin crystal 65g, Cortex Hibisci 8g, propolis 50g, Semen pini koraiensis oil 0.9g, Radix Angelicae Dahuricae 4g and Galla Chinensis 25g.
Medicine of the present invention can be prepared into any conventional external-applied ointment, the cold compress affected part, and the skin that festers can be coated with directly outward, repeats external application and reaches till the certain thickness, need not aviod certain food.
Amount of drug of the present invention can also be:
Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 10-30g, Resina Cupressi resin crystal 50-80g, Cortex Hibisci 5-10g, propolis 40-60g, Semen pini koraiensis oil 0.3-1.5g, Radix Angelicae Dahuricae 1-6g, Galla Chinensis 20-30g, vinegar 10-20g
Be preferably:
Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 20g, Resina Cupressi resin crystal 65g, Cortex Hibisci 8g, propolis 50g, Semen pini koraiensis oil 0.9g, Radix Angelicae Dahuricae 4g, Galla Chinensis 25g, vinegar 16g.
Medicine of the present invention with vinegar and above-mentioned Six-element medicine mix homogeneously after, the volatile oil that extracts this Chinese medicine composition is prepared into atomized inhalation.Suck the period of the day from 5 p.m. to 7 p.m every day, makes medicine go into lung by nose, and through focus is removed paathogenic factor from the source, and with Chinese medicine lotion for external use agent synergy of the present invention, treating both the principal and secondary aspects of a disease, the treatment psoriasis does not recur.
The specific embodiment
Embodiment one:
(a) take by weighing Cortex Hibisci 8g, Radix Angelicae Dahuricae 4g and Galla Chinensis 25g, pulverize adds Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 20g, Resina Cupressi resin crystal 65g, propolis 50g, Semen pini koraiensis oil 0.9g more altogether, mix homogeneously, and common the decoction is prepared into ointment.
(b) psoriasis, object for appreciation tinea eczema ulcer and seborrheic keratosis patient, with above-mentioned ointment cold compress affected part, the skin that festers can be coated with directly outward, repeats external application and reaches certain thickness, once a day.
(c) use the patient of Chinese medicine composition ointment of the present invention to aviod certain food.
Embodiment two:
(a) take by weighing Cortex Hibisci 8g, Radix Angelicae Dahuricae 4g and Galla Chinensis 25g, pulverize adds Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 20g, Resina Cupressi resin crystal 65g, propolis 50g, Semen pini koraiensis oil 0.9g, mix homogeneously, the common decoction more altogether.
(b) when upper solution and the obvious different oil reservoirs of lower floor's solution occurring floating over, promptly during volatile oil, stop heating,, be sealed in the container slowly with its sucking-off with syringe or other instruments.
Volatile oil can be put into the atomizing bottle that small nozzle is arranged general commonly used of pressurization when (c) packing.
(d) psoriasis, eczema ulcer and seborrheic keratosis patient use the atomized inhalation of Chinese medicine composition of the present invention every day in the period of the day from 5 p.m. to 7 p.m, and via intranasal application sucks, once a day.
(e) use the patient of the atomized inhalation of Chinese medicine composition of the present invention to aviod certain food.
The clinical observation on the therapeutic effect experiment of Chinese medicine composition of the present invention
1, physical data
Accept clinical psoriatic's 40 examples for medical treatment, male's 30 examples, women's 10 examples.
Age: 15-25 year 10 examples, 25-40 year 20 examples, 40-60 year 10 examples.
Medical history: 3-6 10 examples, 6-10 20 examples, 10-25 and above 10 examples, the ill position of patient is mostly at collare, extremity, the back, 10 years above patients of medical history, bigger red pimple of area or silvery white squama appear in abdominal part.
2, diagnostic criteria
(1) homeliness type psoriasis: erythra generally occurs in scalp, trunk, extremity are stretched side, are to occur red pimple on skin, and flaring is fused into patch or speckle greatly, there are thicker silvery white phosphorus bits on the surface, out-of-shape, and what have has map or an island sample outward appearance, the skin lesion that has is less, more, be the Caulis et folium pavettae hongkongensis outward appearance, squama layer one deck comes off, wipe scurf gently off and can see the red film of very thin one deck, strike off red film and can see slight petechia, have person to reveal, medically make the sieve shape hemorrhage again for blood.
(2) erythrodermic psoriasis: this kind of is meant and is the diffusivity redness more than 70% at about whole skin, kermesinus wellability skin lesion, there are a large amount of bran skin sample scurfs on the surface, sometimes in the oxter, thigh root and umbilical part make exfoliation because of swelling and ooze out, oropharynx nose and eye conjunctiva can be congested rubescent, and the patient often has heating fear of cold, symptoms such as headache and general malaise.
(3) pustule type psoriasis: mostly be acute onset, can be in a few days to several weeks general whole body of pustule, the intensive potential pimple of needle point size is arranged earlier, be fused into the pus lake very soon, often with hyperpyrexia, arthralgia and general malaise, routine blood test is chemically examined visible leukocytosis, after abscess is dry, desquamation after scurf comes off, has new abscess to occur again immediately.
(4) psoriasis arthropathica: can betide big or small joint simultaneously, but common be the little joint of wrist, finger and toes, joint of vertebral column also can take place.The joint of pathological changes has redness, pain, serious articular cavity that hydrops is arranged, juxtra-articular skin turgor limitation of activity, joint stiffness of a specified duration, the ruined situation in visible joint under X line when serious, erythrocyte sedimentation rate is fast, General Symptomies such as the heat that often occurs together, but rheumatoid agglutinating factor is negative, how psoriasis arthropathica, skin lesion also can only have the skin lesion of homeliness type psoriasic erythema and silver bits with the ostraceous skin lesion of thick picture.
3, Therapeutic Method
Differently with medical history length be equally divided into two groups with above-mentioned 40 routine patients are age-based, experimental group and matched group, M-F is 3/1,
Experimental group uses the unguentum and the atomized inhalation of Chinese medicine composition of the present invention: with the unguentum cold compress of this Chinese medicine composition or smear the affected part once a day; With the atomized inhalation of this Chinese medicine composition, via intranasal application sucks, and use once period of the day from 5 p.m. to 7 p.m every day.
Matched group adopts routine clinical Therapeutic Method to treat, and does not use Chinese medicine composition provided by the present invention.
Two months is a course of treatment, observes four courses of treatment continuously, and experimental group is cured the back and continued two courses of treatment of after treatment.
4, curative effect determinate standard
(1) cure: after medication four courses of treatment, the complete obiteration of silver bits speckle, the skin ulcer healing replaces the skin with normal color, after patient's pustule ulceration that medical history is long disappears, no longer repeats new pustule, consolidate medication two courses of treatment after, no longer recurrence.
(2) effective: after medication three courses of treatment, disappearances that begin to come off of skin silver bits, the petechia disappears, and the skin affected part takes on a red color, and limb vessel recovers elasticity, and blood fortune is enriched.
(3) produce effects: after medication two courses of treatment, former affected part and medication are got rid of the position and can be eliminated more than the 90%-95%, and other positions are primary lesion.
(4) invalid: the medication course of treatment or a longer time person, skin does not have improvement, and arthritis is without any improvement, and the psoriasis symptom does not have and alleviates even increase the weight of.
5, therapeutic outcome sees Table 1
The comparison (example) of table 1 clinical treatment psoriasis effect
| Group | First course of treatment of produce effects | Effective second course of treatment | Cured for the 4th course of treatment | Invalid | Cure rate (%) |
| Experimental group | 18 | 19 | 19 | 1 | 95 |
| Matched group | 8 | 10 | 10 | 10 | 50 |
After medication course of treatment, the obvious effective rate of experimental group is 90%, and the obvious effective rate of matched group is 40%.
Two courses of treatment of medication, the original psoriasis of the patient of the experimental group position 90%-95% that disappears, and no longer include new site of pathological change and occur; Matched group only has 10 routine patients improvement situations such as psoriasis desquamation to occur, and effective percentage is 50%.
The cure rate of experimental group is 95% after medication four courses of treatment, and the cure rate of using the matched group of conventional therapy only is 50%.The experimental group continuous use is after six courses of treatment, cures and the patient that do not have a recurrence symptom is 19 examples, and cure rate is 95%.It is longer that the reason of failing to respond to any medical treatment mostly is medical history, is in a bad way or influenced psoriasis treatment with other diseases.
After above-mentioned 40 routine psoriatics cure again clinical trail paid a return visit 1 year, experimental group is used the 19 routine patients that Chinese medicine composition of the present invention cures and is not all recurred, psoriasis is thoroughly cured, relapse rate is 0.
In the matched group to the 10 routine patients that cured after the clinical trail in 1 year is paid a return visit, have 8 routine patients to recur psoriasis spring or the winter in 1 year, relapse rate is 80%.
Claims (6)
1. the psoriasic Chinese medicine composition of treatment is characterized in that this Chinese medicine composition is made up of following raw materials by weight proportions: Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 10-30g, Resina Cupressi resin crystal 50-80g, Cortex Hibisci 5-10g, propolis 40-60g, Semen pini koraiensis oil 0.3-1.5g, Radix Angelicae Dahuricae 1-6g, Galla Chinensis 20-30g.
2. the psoriasic Chinese medicine composition of treatment according to claim 1 is characterized in that wherein the consumption of each component is: Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 20g, Resina Cupressi resin crystal 65g, Cortex Hibisci 8g, propolis 50g, Semen pini koraiensis oil 0.9g, Radix Angelicae Dahuricae 4g, Galla Chinensis 25g.
3. the psoriasic Chinese medicine composition of treatment according to claim 1 and 2, it is characterized in that the method for preparing this Chinese medicine composition is: each crude drug that takes by weighing above-mentioned weight proportion, raw material Cortex Hibisci, the Radix Angelicae Dahuricae and Galla Chinensis are ground to form powdery, add Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil, Resina Cupressi resin crystal, propolis and Semen pini koraiensis oil, the common decoction is prepared into ointment and gets final product.
4. the psoriasic Chinese medicine composition of treatment is characterized in that this Chinese medicine composition also can be made up of following raw materials by weight proportions: Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 10-30g, Resina Cupressi resin crystal 50-80g, Cortex Hibisci 5-10g, propolis 40-60g, Semen pini koraiensis oil 0.3-1.5g, Radix Angelicae Dahuricae 1-6g, Galla Chinensis 20-30g, vinegar 10-20g.
5. the psoriasic Chinese medicine composition of treatment according to claim 4 is characterized in that wherein the consumption of each component is: Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil 20g, Resina Cupressi resin crystal 65g, Cortex Hibisci 8g, propolis 50g, Semen pini koraiensis oil 0.9g, Radix Angelicae Dahuricae 4g, Galla Chinensis 25g, vinegar 16g.
6. according to claim 4 or the psoriasic Chinese medicine composition of 5 described treatments, it is characterized in that the method for preparing this Chinese medicine composition comprises:
(a) take by weighing each crude drug of above-mentioned weight proportion, raw material Cortex Hibisci, the Radix Angelicae Dahuricae and Galla Chinensis are ground to form powdery, add Lignum seu Ramulus Cunninghamiae Lanceolatae resin oil, Resina Cupressi resin crystal, propolis, Semen pini koraiensis oil and white vinegar, the common decoction;
(b) when upper solution and the obvious different oil reservoirs of lower floor's solution occurring floating over, promptly during volatile oil, stop heating,, be sealed in the container slowly with its sucking-off with syringe or other instruments;
When (c) packing volatile oil is put into the atomizing bottle that small nozzle is arranged of pressurization.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100171160A CN101327231B (en) | 2008-06-20 | 2008-06-20 | Chinese medicinal composition for treating psoriasis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100171160A CN101327231B (en) | 2008-06-20 | 2008-06-20 | Chinese medicinal composition for treating psoriasis |
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| CN101327231A CN101327231A (en) | 2008-12-24 |
| CN101327231B true CN101327231B (en) | 2010-12-29 |
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| CN2008100171160A Expired - Fee Related CN101327231B (en) | 2008-06-20 | 2008-06-20 | Chinese medicinal composition for treating psoriasis |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772541B (en) * | 2012-07-31 | 2016-03-02 | 富阳原野生物科技有限公司 | A kind of oil preparation medicine for the treatment of tinea versicolor |
| CN107095989A (en) * | 2017-05-31 | 2017-08-29 | 王滋东 | One kind treats psoriasic Chinese medicine and preparation method thereof |
| CN107670026A (en) * | 2017-10-25 | 2018-02-09 | 界首市菁华科技信息咨询服务有限公司 | One kind is used to prevent antipsoriatic spray and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1174064A (en) * | 1997-07-18 | 1998-02-25 | 迟经惠 | Eczema ointment |
| CN1273111A (en) * | 2000-03-30 | 2000-11-15 | 朱江 | Ointment for treating skin tinea |
| CN1280853A (en) * | 1999-07-20 | 2001-01-24 | 罗国栋 | Baicao skin lotion and its preparing process |
-
2008
- 2008-06-20 CN CN2008100171160A patent/CN101327231B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1174064A (en) * | 1997-07-18 | 1998-02-25 | 迟经惠 | Eczema ointment |
| CN1280853A (en) * | 1999-07-20 | 2001-01-24 | 罗国栋 | Baicao skin lotion and its preparing process |
| CN1273111A (en) * | 2000-03-30 | 2000-11-15 | 朱江 | Ointment for treating skin tinea |
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