CN101306086A - Broussonetia papyrifera leaves health obesity attenuation capsule and its preparation method - Google Patents

Broussonetia papyrifera leaves health obesity attenuation capsule and its preparation method Download PDF

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CN101306086A
CN101306086A CNA2007101075240A CN200710107524A CN101306086A CN 101306086 A CN101306086 A CN 101306086A CN A2007101075240 A CNA2007101075240 A CN A2007101075240A CN 200710107524 A CN200710107524 A CN 200710107524A CN 101306086 A CN101306086 A CN 101306086A
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precipitate
folium nelumbinis
diluent
leaf
extract
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CN101306086B (en
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刘尚文
刘畅
汪红
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Liu Chang International Co Ltd
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Liu Chang International Co Ltd
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Abstract

The invention relates to a broussonetia papyrifera leaf health protection and slimming gelatine capsule and a method for preparing the lotus leaf health protection and slimming gelatine capsule. The broussonetia papyrifera leaf health protection and slimming gelatine capsule comprises 50 to 70 parts of broussonetia papyrifera leaf extract and 30 to 50 parts of lotus leaf extract. The broussonetia papyrifera leaf extract is generated by fermenting powdered broussonetia papyrifera leaves with aspergillus and microzyme; the lotus leaf extract is generated by fermenting powdered lotus leaves with aspergillus and microzyme. After the powdered broussonetia papyrifera leaves are fermented, protein is resolved into polypeptide and amino acid, and can activate lipolytic enzymes. After the lipolytic enzymes are activated, the breakdown rate of excess fat in human bodies is significantly improved, and the excess fat is converted into adenosine triphosphate which is the bioenergy necessary for movement of human beings. The broussonetia papyrifera leaf health protection and slimming gelatine capsule can resist cellular oxidation, senility, reduce blood fat, slim and improve the immunity of human bodies.

Description

Broussonetia papyrifera leaves health obesity attenuation capsule and preparation method thereof
Technical field
The present invention relates to a kind of broussonetia papyrifera leaves health obesity attenuation capsule and preparation method thereof, the present invention is fermented leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder and Folium Nelumbinis powder respectively and is made extract, make capsule after then two kinds of extracts being mixed, this capsule contains multiple functional peptide and aminoacid, energy human activin lipolytic enzyme, but anti-cell oxidation, defying age, blood fat reducing fat-reducing strengthen body immunity.
Technical background
Broussonetia papyrifera (Broussonetia papyrifera Vant) deciduous tree, or shrub are the liana shape sometimes, dioecism, well developed root system, leaf alternate, width egg shape is to apart from the circle shape, and is avette, long 7-10 centimetre, wide 6-15 centimetre, edge tool rough sawn tooth does not split or irregular 3-5 drastic crack, above close by short stalk hair, coarse, below close villosity, be distributed in province surplus Ji, Shanxi, Shan, sweet, Hubei and Hunan Provinces, Guangdong and Guangxi Provinces, cloud, expensive, river etc. 20.Scientific research confirms, leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. not only can be used for producing good animal and fowl fodder (is 02104092.3 disclosed description referring to the patent No.), can also human consumption and as medical material, has health care, but, also do not have a kind of processing mode can make protein, vitamin, trace element and polyphenols in the leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. be easy to absorption by human body at present.Therefore, need to propose a kind of broussonetia papyrifera leaves health obesity attenuation capsule and preparation method thereof.
Summary of the invention
The object of the present invention is to provide a kind of broussonetia papyrifera leaves health obesity attenuation capsule, the present invention is fermented leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder and Folium Nelumbinis powder respectively and is made extract, make capsule after then two kinds of extracts being mixed, this capsule contains protein, multiple functional peptide, aminoacid, vitamin, trace element and polyphenols such as flavonoid, tannin, energy human activin lipolytic enzyme, accelerated the decomposition rate to superabundant fats in the human body greatly, making it metabolic conversion is necessary bio-energy three phosphorus of physical activity three adenosines.Take this capsule, but not only anti-cell oxidation, defying age, blood fat reducing fat-reducing, also favourable sleep and rest, enhancing body immunity.
The objective of the invention is to realize by following technical proposals: a kind of broussonetia papyrifera leaves health obesity attenuation capsule, comprise structure leaf extract, Folium Nelumbinis extract, the weight portion proportioning of described extract is:
Structure leaf extract 50-70 part
Folium Nelumbinis extract 30-50 part;
Described structure leaf extract is generated through aspergillosis and yeast fermentation by the leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder, and described Folium Nelumbinis extract is generated through aspergillosis and yeast fermentation by Folium Nelumbinis powder.
Another object of the present invention provides a kind of preparation method of broussonetia papyrifera leaves health obesity attenuation capsule, utilizes microbial fermentation technology that leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder and Folium Nelumbinis are prepared into capsule, material in the raw material is changed into multiple functional peptide and the aminoacid that is easy to absorption of human body.
Another object of the present invention is realized by following technical proposals: a kind of preparation method of broussonetia papyrifera leaves health obesity attenuation capsule is a raw material by leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder, Folium Nelumbinis powder, and preparation process is as follows:
The preparation of I, structure leaf extract:
A, with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. dry in the sun, oven dry, the pulverizing cleaned, cross 300 mesh sieves and make the leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder;
B, with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder inoculation aspergillosis liquid and yeast liquid, 25-40 ℃ of condition bottom fermentation 12-48 hour, obtain leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. yeast powder;
C, with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. yeast powder with 50-60 ℃ of warm water soaking 24 hours, in soak, add hydrochloric acid then, make the pH value of this soak reach 1-2, the continuous stirring soak was handled soak acidolysis under 50-60 ℃ of temperature conditions 20-30 hour;
After D, acidolysis are finished dealing with, in described soak, add sodium hydroxide, make the pH value of this soak reach 4.5-5.0, leave standstill more than 8 hours, remove supernatant, obtain structure leaf precipitate one time;
E, described structure leaf precipitate is added 3-5 pure water doubly part by volume be diluted to the precipitate diluent,, make the pH value of this diluent reach 1-2, this diluent is carried out centrifugal treating, remove precipitate, obtain structure leaf supernatant again to wherein adding hydrochloric acid;
F, in described structure leaf supernatant, add sodium hydroxide, make the pH value of this supernatant reach 4.5-5.0, leave standstill more than 8 hours, this structure leaf supernatant is carried out centrifugal treating, obtain secondary structure leaf precipitate;
G, described secondary structure leaf precipitate is added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, this precipitate diluent is carried out centrifugal dehydration treatment, obtain structure leaf precipitate three times;
H, described three structure leaf precipitate are added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, and in this diluent, add sodium hydroxide, make the pH value of this diluent reach 4.5-5.0, leave standstill more than 8 hours, this precipitate diluent is carried out centrifugal dehydration treatment, obtain the structure leaf extract, then with the structure leaf extract through 60-65 ℃ of oven dry, be ground into the capsule granule; Mainly contain structure leaf protein matter, polypeptide and ispol in this structure leaf extract;
The preparation of II, Folium Nelumbinis extract:
A, with Folium Nelumbinis dry in the sun, oven dry, the pulverizing cleaned, cross 300 mesh sieves and make Folium Nelumbinis powder;
B, Folium Nelumbinis powder is inoculated aspergillosis liquid and yeast liquid,, obtain Folium Nelumbinis yeast powder 25-40 ℃ of condition bottom fermentation 12-48 hour;
C, with Folium Nelumbinis yeast powder with 50-60 ℃ of warm water soaking 24 hours, in soak, add hydrochloric acid then, make the pH value of this soak reach 1-2, the continuous stirring soak was handled soak acidolysis under 50-60 ℃ of temperature conditions 20-30 hour;
After D, acidolysis are finished dealing with, in described soak, add sodium hydroxide, make the pH value of this soak reach 4.5-5.0, leave standstill more than 8 hours, remove supernatant, obtain one time the Folium Nelumbinis precipitate;
E, described Folium Nelumbinis precipitate is added 3-5 pure water doubly part by volume be diluted to the precipitate diluent,, make the pH value of this diluent reach 1-2, this diluent is carried out centrifugal treating, remove precipitate, obtain the Folium Nelumbinis supernatant again to wherein adding hydrochloric acid;
F, in described Folium Nelumbinis supernatant, add sodium hydroxide, make the pH value of this supernatant reach 4.5-5.0, leave standstill more than 8 hours, this Folium Nelumbinis supernatant is carried out centrifugal treating, obtain secondary Folium Nelumbinis precipitate;
G, described secondary Folium Nelumbinis precipitate is added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, this precipitate diluent is carried out centrifugal dehydration treatment, obtain three times the Folium Nelumbinis precipitate;
H, described three Folium Nelumbinis precipitate are added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, and in this diluent, add sodium hydroxide, make the pH value of this diluent reach 4.5-5.0, leave standstill more than 8 hours, this diluent is carried out centrifugal dehydration treatment, obtain Folium Nelumbinis extract, then with Folium Nelumbinis extract through 60-65 ℃ of oven dry, be ground into the capsule granule; Mainly contain Folium Nelumbinis protein, polypeptide and ispol in this Folium Nelumbinis extract;
III, with described structure leaf extract and described Folium Nelumbinis extract according to 50-70 part: the weight portion proportioning of 30-50 part is mixed, divide behind the mix homogeneously encapsulated, every capsules packing 0.2-0.3 gram.
Compared with the prior art the present invention has following advantage:
1, primary raw material wide material sources of the present invention utilize microbial fermentation technology, low processing cost.
2, be rich in protein, polypeptide, aminoacid, vitamin, trace element and the polyphenols that is easy to absorption of human body in the capsule of the present invention, have anti-cell oxidation, defying age, blood fat reducing antiobesity action, have various health-care.
3, contain multiple functional peptide and aminoacid in the capsule of the present invention, energy human activin lipolytic enzyme, accelerated decomposition rate greatly, made it to be converted into necessary bio-energy three phosphorus, three adenosines of physical activity (ATP), strengthened body immunity superabundant fats in the human body.
The specific embodiment
Embodiment one:
A kind of broussonetia papyrifera leaves health obesity attenuation capsule comprises structure leaf extract, Folium Nelumbinis extract, and the weight portion proportioning of described extract is:
Structure leaf extract 50-70 part
Folium Nelumbinis extract 30-50 part;
Described structure leaf extract is generated through aspergillosis and yeast fermentation by the leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder, and described Folium Nelumbinis extract is generated through aspergillosis and yeast fermentation by Folium Nelumbinis powder.
In the present embodiment, divide encapsulated according to the weight portion proportioning behind structure leaf extract and the Folium Nelumbinis extract mix homogeneously, every capsules packing 0.2-0.3 gram, the structure leaf extract can be chosen arbitrarily in 50-70 part scope, and Folium Nelumbinis extract can be chosen arbitrarily in 30-50 part scope.Take mode: every day the 2-4 grain, body weight surpasses 90 kilograms of persons suitably increases the 1-2 grains every day.
The capsular preparation method that relates in the present embodiment can be referring to embodiment two.
Embodiment two:
A kind of preparation method of broussonetia papyrifera leaves health obesity attenuation capsule is a raw material by leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder, Folium Nelumbinis powder, and preparation process is as follows:
The preparation of I, structure leaf extract:
A, the leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. of gathering 70 kilograms are cleaned, and with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. dry in the sun, oven dry, the pulverizing of cleaning, cross 300 mesh sieves and make the leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder;
B, with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder inoculation aspergillosis liquid and yeast liquid, per 100 gram leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder inoculation 1-5 milliliter bacterium liquid placed wooden or bamboo koji tray then, 25-40 ℃ of condition bottom fermentation 12-48 hour, obtain leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. yeast powder, present embodiment can use conventional Zymolysis Equipment;
C, with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. yeast powder with 50-60 ℃ of warm water soaking 24 hours, in soak, add hydrochloric acid then, make the pH value of this soak reach 1-2, use conventional blender continuous stirring soak, soak acidolysis under 50-60 ℃ of temperature conditions was handled 20-30 hour; Use conventional container handling;
After D, acidolysis are finished dealing with, in described soak, add sodium hydroxide, make the pH value of this soak reach 4.5-5.0, leave standstill more than 8 hours, remove supernatant, obtain structure leaf precipitate one time;
E, described structure leaf precipitate is added 3-5 pure water doubly part by volume be diluted to the precipitate diluent,, make the pH value of this diluent reach 1-2, this diluent is carried out centrifugal treating, remove precipitate, obtain structure leaf supernatant again to wherein adding hydrochloric acid;
F, in described structure leaf supernatant, add sodium hydroxide, make the pH value of this supernatant reach 4.5-5.0, leave standstill more than 8 hours, this structure leaf supernatant is carried out centrifugal treating, obtain secondary structure leaf precipitate;
G, described secondary structure leaf precipitate is added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, this precipitate diluent is carried out centrifugal dehydration treatment, obtain structure leaf precipitate three times;
H, described three structure leaf precipitate are added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, and in this diluent, add sodium hydroxide, make the pH value of this diluent reach 4.5-5.0, leave standstill more than 8 hours, this precipitate diluent is carried out centrifugal dehydration treatment, obtain the structure leaf extract, then with the structure leaf extract through 60-65 ℃ of oven dry, be ground into the capsule granule; Mainly contain structure leaf protein matter, polypeptide and ispol in this structure leaf extract;
The preparation of II, Folium Nelumbinis extract:
A, the Folium Nelumbinis of gathering 50 kilograms are cleaned, and with Folium Nelumbinis dry in the sun, oven dry, the pulverizing of cleaning, cross 300 mesh sieves and make Folium Nelumbinis powder;
B, Folium Nelumbinis powder is inoculated aspergillosis liquid and yeast liquid, per 100 gram Folium Nelumbinis powder inoculation 1-5 milliliter bacterium liquid place wooden or bamboo koji tray then, 25-40 ℃ of condition bottom fermentation 12-48 hour, obtain Folium Nelumbinis yeast powder; Present embodiment can use conventional Zymolysis Equipment;
C, with Folium Nelumbinis yeast powder with 50-60 ℃ of warm water soaking 24 hours, in soak, add hydrochloric acid then, make the pH value of this soak reach 1-2, use conventional blender continuous stirring soak, soak acidolysis under 50-60 ℃ of temperature conditions was handled 20-30 hour; Use conventional container handling;
After D, acidolysis are finished dealing with, in described soak, add sodium hydroxide, make the pH value of this soak reach 4.5-5.0, leave standstill more than 8 hours, remove supernatant, obtain one time the Folium Nelumbinis precipitate;
E, described Folium Nelumbinis precipitate is added 3-5 pure water doubly part by volume be diluted to the precipitate diluent,, make the pH value of this diluent reach 1-2, this diluent is carried out centrifugal treating, remove precipitate, obtain the Folium Nelumbinis supernatant again to wherein adding hydrochloric acid;
F, in described Folium Nelumbinis supernatant, add sodium hydroxide, make the pH value of this supernatant reach 4.5-5.0, leave standstill more than 8 hours, this Folium Nelumbinis supernatant is carried out centrifugal treating, obtain secondary Folium Nelumbinis precipitate;
G, described secondary Folium Nelumbinis precipitate is added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, this precipitate diluent is carried out centrifugal dehydration treatment, obtain three times the Folium Nelumbinis precipitate;
H, described three Folium Nelumbinis precipitate are added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, and in this diluent, add sodium hydroxide, make the pH value of this diluent reach 4.5-5.0, leave standstill more than 8 hours, this precipitate diluent is carried out centrifugal dehydration treatment, obtain Folium Nelumbinis extract, then with Folium Nelumbinis extract through 60-65 ℃ of oven dry, be ground into the capsule granule; Mainly contain Folium Nelumbinis protein, polypeptide and ispol in this Folium Nelumbinis extract;
III, with described structure leaf extract and described Folium Nelumbinis extract according to 50-70 part: the weight portion proportioning of 30-50 part is mixed, divide behind the mix homogeneously encapsulated, every capsules packing 0.2-0.3 gram.
In the present embodiment, the weight portion proportioning of described structure leaf extract and described Folium Nelumbinis extract can be 50-70 part: choose arbitrarily in 30-50 part proportion, do not exemplify one by one at this.
Leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder, Folium Nelumbinis powder by fermentation after, protein is decomposed into polypeptide and aminoacid, wherein, contain multiple functional peptide, as contain the little peptide of 10-15 amino acid molecular, can activate lipolytic enzyme, after these lipolytic enzymes are activated, accelerated decomposition rate greatly, made it to be converted into necessary bio-energy three phosphorus, three adenosines of physical activity (ATP) superabundant fats in the human body.Simultaneously, human body has absorbed a large amount of necessary aminoacid again, consequently, takes this kind slimming capsule, not only can not make the people feel weak, and can not lack necessary nutrition again.
Result of use of the present invention is observed:
Participate in test crowd woman surname 10 people, male surname 10 people, age group is 20-40 year, 41-60 year.Do not have a routine untoward reaction and a side effect, the obvious effective rate of fat-reducing effect reaches more than 95%, and concrete data are as follows:
1.61 meters of Mries Fang, 42 years old, height, body weight is 68 kilograms before the test, takes the present invention's 58 kilograms of body weight after six months, takes twice every day, and it is slightly rare to take three days stool, and it is soft to defecate later on, once a day; Taking January conscious mottle on the face obviously goes down.
Body weight is 69 kilograms before Ms Zhang, 54 years old, 1.58 meters of heights, the test, takes the present invention's 54 kilograms of body weight after six months, and take 2-3 every day, take first week stool slightly rare, later on stool normally, once a day; Take all abdominal part proud flesh and obviously reduce, it is normal to have a meal, the sensation spiritedness.
1.62 meters of Mries Lin, 21 years old, height, body weight is 69 kilograms before the test, takes the present invention's 53.5 kilograms of body weight after six months, takes every day 2 times, and it is slightly rare to take two days stool, twice of every day; Stool is soft later on, once a day; Take abdominal part deliquescing in the January waist of trousers and obviously fluff, appetite descends, and it is normal to have a meal, and does not want to have eaten a piece.
1.62 meters of Mries Yang, 33 years old, height, body weight is 72 kilograms before the test, takes the present invention's 63 kilograms of body weight after six months, takes every day 1 time, and it is slightly rare to take three days stool, every day 2-3 time; Stool is soft later on, once a day; Take all abdominal part proud flesh and obviously reduce, the tight lattice of belt; Take most of disappearance of abdominal part proud flesh in March; The normal spiritedness of having a meal.
1.61 meters of Mries Han, 26 years old, height, body weight is 70 kilograms before the test, takes the present invention's 55 kilograms of body weight after six months, takes every day 1 time, and it is rare to take three days stool, every day 2-3 time; Stool is soft later on, once a day; Take January abdominal part proud flesh and obviously reduce, appetite reduces; Take half a year abdominal part proud flesh and disappear substantially, the sensation health is easily in high spirits.
1.58 meters of Mries Huang, 55 years old, height, body weight is 69 kilograms before the test, takes the present invention's 57 kilograms of body weight after six months, takes every day 2 times, take first week stool rare, every day 3 times; Stool is soft later on, every day 2-3 time; Take all abdominal part deliquescing waist of trousers and obviously fluff, take most of disappearance of abdominal part proud flesh half a year, the sensation health is easily in high spirits.
1.59 meters of Mries Lin, 48 years old, height, body weight is 72 kilograms before the test, takes the present invention's 58 kilograms of body weight after six months, take every day 2 times, in the past, appetrol both domestic and external were eaten many, or did not have effect, react uncomfortable greatly, begin also not embrace much hope specifically, I had never expected and take abdominal part deliquescing in three days, lost weight 8 jin after one month, and health do not have uncomfortable feeling, and belly has not risen again gas yet.
1.64 meters of Mries Hu, 28 years old, height, body weight is 71 kilograms before the test, takes the present invention's 60 kilograms of body weight after six months, takes every day 1 time, and it is rare to take three days stool, twice of every day; Stool is soft later on, once a day; Take January abdominal part proud flesh and obviously reduce, appetite is normal; Take half a year abdominal part proud flesh and disappear substantially, the light skin of sensation health is good.
1.60 meters of Mries Lin, 52 years old, height, body weight is 74.5 kilograms before the test, takes the present invention's 57.5 kilograms of body weight after six months, takes every day 1 time, takes multiple appetrol, feels that this slimming capsule effect is best! Do not have the reaction of diarrhoea, it is unaffected to eat, and proud flesh obviously reduces, and skin shows gloss.
1.64 meters of Mries Tan, 38 years old, height, body weight is 71 kilograms before the test, take the present invention's 57 kilograms of body weight after six months, take every day 1 time, just get fat always, take multiple fat-reducing measure since the back of giving birth to a child, all not quite do not adhere to getting off because of effect, it is obvious to take effect specifically, loses weight tens jin, and does not have uncomfortable feeling in one month.
Turn round and look at 1.78 meters of men, 17 years old, height, body weight is 102 kilograms before the test, takes the present invention's 79 kilograms of body weight after six months, takes every day 1 time, takes January abdominal part proud flesh and obviously reduces tight two lattice of belt; Taking March abdominal part proud flesh disappears substantially; The normal psyche of having a meal is good.
1.75 meters of Li men, 40 years old, height, body weight is 98 kilograms before the test, takes the present invention's 78 kilograms of body weight after six months, takes every day 1 time, and it is slightly rare to take three days stool, twice of every day; Stool is soft later on, once a day; Take January abdominal part proud flesh and obviously reduce tight two lattice of belt; Taking March abdominal part proud flesh disappears substantially; The normal psyche of having a meal is good.
1.68 meters of Mr.s Tian, 58 years old, height, body weight is 93 kilograms before the test, takes the present invention's 76 kilograms of body weight after six months, takes every day 1 time, take first week stool slightly rare, every day 3 times; The back stool is soft, once a day; Take all abdominal part deliquescing waist of trousers and obviously fluff the tight lattice of belt; Take most of disappearance of abdominal part proud flesh in March; Spiritedness, face is good, the appetite no change, aerofluxus increases, the sensation complete obiteration that tripe expands.
1.75 meters of Mr. Lius, 48 years old, height, body weight is 91 kilograms before the test, takes the present invention's 69 kilograms of body weight after six months, takes every day 1 time, and it is rare to take three days stool, twice of every day; Later on stool is soft, every day secondary; Take January abdominal part proud flesh and obviously reduce the abdominal part deliquescing; Take most of disappearance of abdominal part proud flesh in March; The normal spiritedness of having a meal.
1.80 meters of Mr.s Xu, 38 years old, height, body weight is 99.5 kilograms before the test, takes the present invention's 76.5 kilograms of body weight after six months, takes every day 2 times, takes abdominal part deliquescing in the January waist of trousers and obviously fluffs, and appetite descends; It is tight to take abdominal muscles change in March, and waistline reduces 3 cun, the light spiritedness of conscious health.
1.72 meters of Mr.s Luo, 54 years old, height, body weight is 85 kilograms before the test, takes the present invention's 68.5 kilograms of body weight after six months, takes every day 2 times, takes all abdominal part deliquescing waist of trousers and obviously fluffs; Take and lose weight more than 30 jin half a year, conscious healthy in high spirits.
1.73 meters of Mr. Lius, 37 years old, height, body weight is 88 kilograms before the test, takes the present invention's 68 kilograms of body weight after six months, takes every day 1 time, and it is rare to take two days stool, twice of every day; Stool is soft later on, every day 2 times; Take abdominal part deliquescing in the January waist of trousers and obviously fluff, appetite descends; It is tight to take abdominal muscles change in March, and waistline reduces 3 cun, the light spiritedness of conscious health.
1.76 meters of Wu men, 32 years old, height, body weight is 89 kilograms before the test, takes the present invention's 74 kilograms of body weight after six months, takes every day 1 time, takes abdominal part deliquescing in the January waist of trousers and obviously fluffs, and appetite slightly subtracts; Take the March abdominal muscles and become tight, belt is tight three lattice, the light spiritedness of conscious health.
1.70 meters of Wang men, 45 years old, height, body weight is 87 kilograms before the test, takes the present invention's 72 kilograms of body weight after six months, takes every day 2 times, takes all abdominal part deliquescing waist of trousers and obviously fluffs, and takes most of disappearance of abdominal part proud flesh half a year, and the sensation health is easily in high spirits.
1.71 meters of Mr.s Yu, 47 years old, height, body weight is 87 kilograms before the test, takes the present invention's 65 kilograms of body weight after six months, takes every day 2 times, and it is rare to take two days stool, twice of every day; Stool is soft later on, every day 2 times; Take abdominal part deliquescing in the January waist of trousers and obviously fluff, take abdominal muscles change in March tightly, the light spiritedness of conscious health.

Claims (2)

1, a kind of broussonetia papyrifera leaves health obesity attenuation capsule is characterized in that: comprise structure leaf extract, Folium Nelumbinis extract, the weight portion proportioning of described extract is:
Structure leaf extract 50-70 part
Folium Nelumbinis extract 30-50 part;
Described structure leaf extract is generated through aspergillosis and yeast fermentation by the leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder, and described Folium Nelumbinis extract is generated through aspergillosis and yeast fermentation by Folium Nelumbinis powder.
2, a kind of preparation method of broussonetia papyrifera leaves health obesity attenuation capsule is characterized in that: by leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder, Folium Nelumbinis powder is raw material, and preparation process is as follows:
The preparation of I, structure leaf extract:
A, with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. dry in the sun, oven dry, the pulverizing cleaned, cross 300 mesh sieves and make the leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder;
B, with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. powder inoculation aspergillosis liquid and yeast liquid, 25-40 ℃ of condition bottom fermentation 12-48 hour, obtain leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. yeast powder;
C, with leaf of Broussonetia papyrifera (L.) L.Her.ex Vent. yeast powder with 50-60 ℃ of warm water soaking 24 hours, in soak, add hydrochloric acid then, make the pH value of this soak reach 1-2, the continuous stirring soak was handled soak acidolysis under 50-60 ℃ of temperature conditions 20-30 hour;
After D, acidolysis are finished dealing with, in described soak, add sodium hydroxide, make the pH value of this soak reach 4.5-5.0, leave standstill more than 8 hours, remove supernatant, obtain structure leaf precipitate one time;
E, described structure leaf precipitate is added 3-5 pure water doubly part by volume be diluted to the precipitate diluent,, make the pH value of this diluent reach 1-2, this diluent is carried out centrifugal treating, remove precipitate, obtain structure leaf supernatant again to wherein adding hydrochloric acid;
F, in described structure leaf supernatant, add sodium hydroxide, make the pH value of this supernatant reach 4.5-5.0, leave standstill more than 8 hours, this structure leaf supernatant is carried out centrifugal treating, obtain secondary structure leaf precipitate;
G, described secondary structure leaf precipitate is added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, this precipitate diluent is carried out centrifugal dehydration treatment, obtain structure leaf precipitate three times;
H, described three structure leaf precipitate are added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, and in this diluent, add sodium hydroxide, make the pH value of this diluent reach 4.5-5.0, leave standstill more than 8 hours, this precipitate diluent is carried out centrifugal dehydration treatment, obtain the structure leaf extract, then with the structure leaf extract through 60-65 ℃ of oven dry, be ground into the capsule granule; Mainly contain structure leaf protein matter, polypeptide and ispol in this structure leaf extract;
The preparation of II, Folium Nelumbinis extract:
A, with Folium Nelumbinis dry in the sun, oven dry, the pulverizing cleaned, cross 300 mesh sieves and make Folium Nelumbinis powder;
B, Folium Nelumbinis powder is inoculated aspergillosis liquid and yeast liquid,, obtain Folium Nelumbinis yeast powder 25-40 ℃ of condition bottom fermentation 12-48 hour;
C, with Folium Nelumbinis yeast powder with 50-60 ℃ of warm water soaking 24 hours, in soak, add hydrochloric acid then, make the pH value of this soak reach 1-2, the continuous stirring soak was handled soak acidolysis under 50-60 ℃ of temperature conditions 20-30 hour;
After D, acidolysis are finished dealing with, in described soak, add sodium hydroxide, make the pH value of this soak reach 4.5-5.0, leave standstill more than 8 hours, remove supernatant, obtain one time the Folium Nelumbinis precipitate;
E, described Folium Nelumbinis precipitate is added 3-5 pure water doubly part by volume be diluted to the precipitate diluent,, make the pH value of this diluent reach 1-2, this diluent is carried out centrifugal treating, remove precipitate, obtain the Folium Nelumbinis supernatant again to wherein adding hydrochloric acid;
F, in described Folium Nelumbinis supernatant, add sodium hydroxide, make the pH value of this supernatant reach 4.5-5.0, leave standstill more than 8 hours, this Folium Nelumbinis supernatant is carried out centrifugal treating, obtain secondary Folium Nelumbinis precipitate;
G, described secondary Folium Nelumbinis precipitate is added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, this precipitate diluent is carried out centrifugal dehydration treatment, obtain three times the Folium Nelumbinis precipitate;
H, described three Folium Nelumbinis precipitate are added 3-5 deionized water doubly part by volume be diluted to the precipitate diluent, and in this diluent, add sodium hydroxide, make the pH value of this diluent reach 4.5-5.0, leave standstill more than 8 hours, this diluent is carried out centrifugal dehydration treatment, obtain Folium Nelumbinis extract, then with Folium Nelumbinis extract through 60-65 ℃ of oven dry, be ground into the capsule granule; Mainly contain Folium Nelumbinis protein, polypeptide and ispol in this Folium Nelumbinis extract;
III, with described structure leaf extract and described Folium Nelumbinis extract according to 50-70 part: the weight portion proportioning of 30-50 part is mixed, divide behind the mix homogeneously encapsulated, every capsules packing 0.2-0.3 gram.
CN2007101075240A 2007-05-18 2007-05-18 Broussonetia papyrifera leaves health obesity attenuation capsule and its preparation method Expired - Fee Related CN101306086B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103037880A (en) * 2010-07-02 2013-04-10 株式会社爱茉莉太平洋 Composition containing paper mulberry extracts
CN103652307A (en) * 2013-12-03 2014-03-26 山西医科大学 Method for extracting leaf proteins from broussonetia papyrifera leaf dry powder and comprehensive utilization of waste
CN103931866A (en) * 2014-04-24 2014-07-23 陈华 Process for producing high-grade nutrition powder by using paper mulberry leaves
CN110974869A (en) * 2020-01-03 2020-04-10 吉林大学 Application of broussonetia papyrifera leaf crude extract in preparation of medicine for treating non-alcoholic fatty liver disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1237990C (en) * 2003-01-17 2006-01-25 南京大学 Spartina capsules for reducing blood fat and its prodn. technique

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103037880A (en) * 2010-07-02 2013-04-10 株式会社爱茉莉太平洋 Composition containing paper mulberry extracts
CN103037880B (en) * 2010-07-02 2015-09-16 株式会社爱茉莉太平洋 The compositions of the extract containing Broussonetia papyrifera
CN103652307A (en) * 2013-12-03 2014-03-26 山西医科大学 Method for extracting leaf proteins from broussonetia papyrifera leaf dry powder and comprehensive utilization of waste
CN103652307B (en) * 2013-12-03 2015-06-17 山西医科大学 Method for extracting leaf proteins from broussonetia papyrifera leaf dry powder and comprehensive utilization of waste
CN103931866A (en) * 2014-04-24 2014-07-23 陈华 Process for producing high-grade nutrition powder by using paper mulberry leaves
CN110974869A (en) * 2020-01-03 2020-04-10 吉林大学 Application of broussonetia papyrifera leaf crude extract in preparation of medicine for treating non-alcoholic fatty liver disease

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